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  • 1
    Online Resource
    Online Resource
    Hoboken, NJ :Wiley-Blackwell,
    UID:
    almahu_9949320271102882
    Format: 1 online resource (767 pages)
    ISBN: 9781119432357 (e-book) , 9781119432432 (e-book)
    Additional Edition: Print version: Apoptosis and beyond : the many ways cells die. Hoboken, NJ : Wiley-Blackwell, 2018 ISBN 9781119432425
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books.
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    Hoboken, NJ :Wiley-Blackwell,
    UID:
    almahu_9948599060002882
    Format: 1 online resource (xxii, 249 pages)
    ISBN: 9781119432487 , 1119432480 , 9781119432494 , 1119432499 , 9781119432456 , 1119432456
    Content: "Most medical treatments have been designed for the "average patient." As a result of this "one-size-fits-all-approach," treatments can be very successful for some patients but not for others. This is changing with the emergence of precision medicine, an innovative approach to disease prevention and treatment that takes into account individual differences in people's genes, environments, and lifestyles. Precision medicine gives clinicians tools to better understand the complex mechanisms underlying a patient's health, disease, or condition, and to better predict which treatments will be most effective. Precision or personalized medicine in cancer treatment was once a buzzword, but it is finally becoming a reality with recent advances in imaging, genetic, and biological sciences. The importance of interpatient and intratumor variability has long been recognized, but realistic opportunities to take these into account in cancer care have emerged only recently. Innovations in patient characterization through genomics, proteomics, and metabolomics have opened new avenues to personalize cancer treatment in ways that were not possible before. Furthermore, advances in quantitative assessment of therapeutic response, as provided by functional and molecular imaging, have been critical in the implementation of precision medicine paradigm in radiation oncology. This book will be a comprehensive review of science and technology making precision medicine possible for radiation oncology, current examples and future direction"--
    Note: Genomic Strategies for Personalized Cancer Therapy -- Blood-based biomarkers for the diagnosis and prognosis of cancer -- Application of circulating cell free DNA for personalized cancer therapy -- Prognostic Implications of EGFR, p53, p16, cyclin D1, Bcl-2 in Head & Neck Squamous Cell Carcinoma (HNSCC) -- Predictive and prognostic markers for cancer medicine -- Dual Energy Imaging in Precision Radiation Therapy -- The role of Big Data in personalized medicine.
    Additional Edition: Print version: Precision medicine in oncology Hoboken, NJ : Wiley-Blackwell, 2021. ISBN 9781119432449
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books. ; Electronic books.
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  • 3
    Online Resource
    Online Resource
    Dordrecht : Springer
    UID:
    gbv_1651958505
    Format: Online-Ressource (V, 198 p. 31 illus., 26 illus. in color, digital)
    ISBN: 9789400754379 , 1283936127 , 9781283936125
    Series Statement: SpringerLink
    Content: “HPV and Cancer” is a concise read that covers all aspects of the Human Papilloma Virus as it relates to human cancers. While written by professionals, it design to be understandable by those that are not in the field, yet it has the technical details that professionals want to stay abreast of this changing field. The book starts out the history of HPV and progresses into the molecular biology of the virus and our current understand of the structure and functions of the proteins and genes it encodes. We then look at the dynamic trends of this infectious agent in the human population, how it interacts with human cells, and the role it plays with other organisms to produce both benign and malignant tumors. Lastly, there is a discussion about a new vaccine for HPV and the hopes that are held by many to change the trends with this virus and the associated cancers it produces.
    Note: Description based upon print version of record , HPV and Cancer; Contents; Human Papillomavirus: A Brief Overview; 1 Introduction; 2 Classification of HPV; 3 The genotype of HPV related to different cancers and diseases; 3.1 Alpha-type papillomavirus; 3.2 Beta-type papillomavirus; 3.3 Gamma, Mu and Nu types; 4 General structure of HPV; 4.1 Genome; 4.2 Capsids Structure; 5 Conclusions; References; Proteins Encoded by the Human Papillomavirus Genome and Their Functions; 1 E1 and E2 Proteins; 2 E6 and E7 Proteins; 3 E4 Proteins; 4 E5 Proteins; 5 L1 and L2 Proteins; 6 Conclusions; References; The Life Cycle of Human Papillomavirus , 1 Introduction2 Infection; 3 Genome Maintenance and Cell Proliferation; 4 Genome Amplification; 5 Virus Assembly and Release; 6 Integration and Tumor Progression; 7 Conclusion; References; Poly-Microbial Interaction with Human Papilloma Virus Leading to Increased Risk for Head and Neck Squamous Cell Carcinoma and Oral Squamous Cell Carcinomas; 1 Poly-Microbial Relationships with Human Papilloma Virus; 2 Poly-Microbial Characteristics and Relationship to Oral Cavity and Pharynx; 3 Poly-Microbial Distribution in Oropharynx and Hypopharynx Tissues , 4 Poly-Microbial Presence Leading to Mucosa Change5 Sites of Microbe Proliferation: Oropharynx and Hypopharynx Tissue and Host Response; 6 Microbial and HPV Invasion Through Mucosa; 7 Streptococci sp. and HPV Capacities for Mucosa Changes; 8 HPV Entry into Keratinocytes; 9 HPV Internalization and Initial Transformation Activity; 10 Microbial Infection and Attachment to HPV/HOK 16B Cells; 11 Microbial Epideminology Associated with Risk for OSCC; 12 Differences Between HPV Associated HNSCC and OSCC; 13 Other Evidence that Microbes Facilitate Cancer Induction: Use of HSGPs , 14 Metabolism of Ethyl Alcohol and Release of Acetaldehyde15 Molecular Changes in Keratinocytes Associated with Bacterial and HPV Infection; References; Patterns and Trends in HPV-Related Oral Cancer and Other HPV-Associated Cancers; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; 4.1 Observations from the Data; 4.2 Detection of HPV/Oral HPV; 5 Conclusions; References; Benign Diseases Associated with Human Papillomavirus Infection; 1 Introduction; 2 Benign HPV Conditions Of Skin; 2.1 Butcher´s Wart; 2.1.1 Clinical Features; 2.1.2 Diagnosis; 2.1.3 Treatment and Prognosis , 2.2 Cystic Wart (Plantar Epidermoid Inclusion Cyst)2.2.1 Clinical Features; 2.2.2 Diagnosis; 2.2.3 Treatment and Prognosis; 2.3 Filiform Wart; 2.3.1 Clinical Features; 2.3.2 Diagnosis; 2.3.3 Treatment and Prognosis; 2.4 Verruca Plana (Flat Wart); 2.4.1 Clinical Features; 2.4.2 Diagnosis; 2.4.3 Treatment and Prognosis; 2.5 Verruca Vulgaris, Including Oral Verruca Vulgaris, Verruca Plantaris, Mosaic Wart, and Periungual Wart; 2.5.1 Clinical Features; 2.5.2 Diagnosis; 2.5.3 Treatment and Prognosis; 3 Benign HPV Conditions of Mucosa and Peri-mucosal Skin; 3.1 Bowenoid Papulosis , 3.1.1 Clinical Features
    Additional Edition: ISBN 9789400754362
    Additional Edition: Buchausg. u.d.T. ISBN 978-94-007-5436-2
    Language: English
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 4
    Online Resource
    Online Resource
    Dordrecht : Springer Netherlands
    UID:
    gbv_1652402373
    Format: Online-Ressource (VII, 1070 p. 364 illus., 275 illus. in color, digital)
    ISBN: 9789400758278
    Series Statement: SpringerLink
    Content: This is a nearly complete collection of Chapters that provide an up to date overview of all aspects of Head and Neck cancer. It is written by professionals but is not only intended for other professionals, but students, patients, policy makers, etc. There are so many aspects to this group of diseases that even the most seasoned professional will learn something from having read this book.
    Content: This is a nearly complete collection of Chapters that provide an up to date overview of all aspects of Head and Neck cancer. It is written by professionals but is not only intended for other professionals, but students, patients, policy makers, etc. There are so many aspects to this group of diseases that even the most seasoned professional will learn something from having read this book
    Note: Includes index , Contents; Chapter 1: Overview of "Head & Neck Cancer: Current Perspectives, Advances, and Challenges"; 1.1 Introduction; Chapter 2: A Disease Without History? Evidence for the Antiquity of Head and Neck Cancers; 2.1 Introduction; 2.2 A First Approximation of the Antiquity of Cancer Writ Large; 2.3 Lines of Evidence; 2.3.1 Artistic Representations; 2.3.2 Historical Records; 2.3.3 Paleopathology; 2.4 Findings; 2.4.1 Artistic Representations of H&NC; 2.4.2 Historical Medical Records of H&NC; 2.4.3 Paleopathology of H&NC; 2.5 Discussion and Conclusion; References , Chapter 3: Head and Neck Cancer Epidemiology and Health Services Research3.1 Introduction; 3.2 Basic Epidemiological Descriptions; 3.2.1 Black Male Disparities; 3.2.2 Global Ranking; 3.3 Common Risk Factors of Head and Neck Cancers; 3.4 Prevention/Interventions; 3.4.1 Tobacco and Alcohol; 3.4.2 HPV; 3.4.3 Nutrition Overview; 3.5 The Cost of Head and Neck Cancer; 3.6 Health Care Professional Practices Regarding Head and Neck Cancer; 3.6.1 Knowledge/Education, Attitudes, and Practices of Healthcare Providers Involved in Prevention and Detection of HNC , 3.6.2 Issues of Delay, Referral and Survival3.7 Conclusions; References; Chapter 4: Challenges in Community-Based Head and Neck Cancer Prevention Programs; 4.1 Introduction; 4.2 Community Collaborative Interventions in Cancer Control; 4.2.1 Community/Academic Collaboration; 4.2.2 Sectors of Community and Channels of Influence; 4.3 Intervention Design; 4.4 Challenges in At-Risk Populations; 4.5 Challenges in Healthcare Provider Communities; 4.6 Practical Matters; 4.7 Summary and Conclusion; References; Chapter 5: Head and Neck Anatomy; 5.1 Nose and Paranasal Sinuses; 5.1.1 Nose , 5.1.1.1 External Nose5.1.1.2 Nasal Skeleton; 5.1.1.3 Vascular Supply and Innervation; 5.1.1.4 Nasal Cavity; 5.1.1.5 Lateral Wall of the Nose; 5.1.1.6 Floor and Roof; 5.1.2 Paranasal Sinuses; 5.1.2.1 Maxillary Sinus; 5.1.2.2 Vascular Supply and Innervation; 5.2 Oral Cavity; 5.2.1 Lips; 5.2.2 Tongue; 5.2.2.1 Musculature of the Tongue; 5.2.2.2 Innervation of the Tongue; 5.2.2.3 Vascular Supply; 5.2.3 Oral Mucosa; 5.2.3.1 Lining Mucosa; 5.2.3.2 Masticatory Mucosa and the Gingivae; 5.2.3.3 Specialized Oral Mucosa; 5.2.4 Floor of the Mouth; 5.2.5 Palate; 5.2.5.1 Hard Palate , Blood Supply and LymphaticsNerve Supply; 5.2.5.2 Soft Palate; 5.2.6 The Teeth; 5.2.7 Cheeks; 5.3 Neck; 5.3.1 Superficial Structures of the Neck; 5.3.1.1 Vascular Supply and Lymphatic Drainage; 5.3.1.2 Innervation; 5.3.2 Deep Fascia; 5.3.2.1 Investing Fascia; 5.3.2.2 Prevertebral Fascia; 5.3.2.3 Pretracheal Fascia; 5.3.2.4 Carotid Sheath; 5.3.3 Triangles of the Neck; 5.3.3.1 The Anterior Triangle; The Digastrics Triangle; The Submental Triangle; The Carotid Triangle; The Muscular Triangle; 5.3.3.2 The Posterior Triangle; The Occipital Triangle; The Subclavian Triangle , 5.3.4 Lymph Nodes of the Neck
    Additional Edition: ISBN 9789400758261
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-94-007-5826-1
    Language: English
    URL: Cover
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  • 5
    Online Resource
    Online Resource
    Hoboken, NJ :Wiley-Blackwell,
    UID:
    edoccha_9958970341402883
    Format: 1 online resource (xiii, 749 pages) : , colour illustrations
    ISBN: 1-119-43243-X , 1-119-43246-4 , 1-119-43235-9
    Content: These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death.-Covers all known processes that dying cells undergo -Provides extensive coverage of a topic not fully covered before -Offers chapters written by top researchers in the field -Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.
    Additional Edition: Print version: Apoptosis and beyond Hoboken, NJ : Wiley-Blackwell, 2018 ISBN 9781119432425
    Language: English
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  • 6
    Online Resource
    Online Resource
    Hoboken, NJ :Wiley-Blackwell,
    UID:
    edocfu_9959328440202883
    Format: 1 online resource
    ISBN: 9781119432432 , 111943243X , 9781119432357 , 1119432359 , 9781119432463 , 1119432464
    Content: These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death.-Covers all known processes that dying cells undergo -Provides extensive coverage of a topic not fully covered before -Offers chapters written by top researchers in the field -Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.
    Additional Edition: Print version: Apoptosis and beyond. Hoboken, NJ : Wiley-Blackwell, 2018 ISBN 9781119432425
    Language: English
    Keywords: Electronic books.
    Library Location Call Number Volume/Issue/Year Availability
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  • 7
    UID:
    almafu_9959242316202883
    Format: 1 online resource (371 p.)
    ISBN: 1-63321-093-6
    Series Statement: Physics Research and Technology
    Note: Description based upon print version of record. , A brief introduction to electromagnatic radiation and UV light / Bulent Aydogan (The University of Chicago: Department of Radiation and Cellular Oncology, Cancer Center, Committee on Medical Physics, Chicago, IL, US) -- Effects of UV pre-treatments on frozen vegetables quality / Filipa I.G. Neves, Margarida C. Vieira and Cristina L.M. Silva (CBQF--Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa/Porto, Rua Dr. António Bernardino Almeida, 4200-072 Porto, Portugal and others) -- Impacts of UV radiation on Caribbean coastal marine ecosystems / Juan L. Torres-Pérez, Roy A. Armstrong and Detrés Yasmín (NASA Ames Research Center, Moffett Field, CA, US and others) -- Melatonin : possible role as light-protector in plants / Marino B. Arnao and Josefa Hernández-Ruiz ( Department of Plant Physiology, University of Murcia, Spain) -- Role of hypoxia and oxidative stress in mutagenesis and metabolic reprogramming : driving forces which induce malignancy with UV-radiation resistance / Humberto De Vitto (University of Milano-Bicocca: Biotechnology and Biosciences Department, Milan, Italy) -- Co-carcinogen and bioenergetic modulation of UV-induced DNA damage / Benjamin C. Thompson, Diona L. Damian and Gary M. Halliday (Discipline of Dermatology, Royal Prince Alfred Hospital, Bosch Institute, University of Sydney, Sydney, Australia) -- Ultraviolet radiation effects on skin cells and immune system / Mariela L. Paz, Eliana M. Cela, Adrián D. Friedrich, Federico S. Weill, Juliana Leoni and Daniel H. González Maglio (Investigadora Asistente, Instituto de Estudios de la Inmunidad Humoral (IDEHU-CONICET) Jefa de Trabajos Prácticos) -- Mechanisms of nitric oxide mediated UV resistance in solid tumors / Madeeha Aqil1 and James A. Radosevich (Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois at Chicago, Chicago, IL, US and others) -- Ultraviolet vision / Kelly D. Garcia and James E. Artwohl (Biologic Resources Laboratory, UIC, University of Illinois at Chicago, Chicago, IL, USA) -- Degradation of emerging aromatic micropollutants by UV-based oxidation prosesses / M. Sánchez-Polo, J. Rivera-Utrilla, R. Ocampo-Perez, J.J. López-Peñalver, I. Velo-Gala and M. Mohamed Mohamed (Departamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Granada, España and others) -- The universe in ultraviolet light / Ana I. Gómez de Castro (Universidad Complutense de Madrid, Facultad de Ciencias Matemáticas, Madrid, Spain) -- The use of UV lasers in fluorescent activated cell sorter analysis / Berna Demircan, Zane Deliu, Ozan A. Alkoc and James A. Radosevich (Istanbul Medeniyet University, Medical School, Department of Medical Biology, Istabul, Turkey and others) -- Applications of ultraviolet radiation to analytical mass spectrometry / Alexandre Giuliani (Synchrotron SOLEIL, L'Orme des Merisiers - Saint Aubin, and CEPIA, Institut National de la Recherche Agronomique (INRA), Rue de la Geraudiere, Nantes, France) -- Effect of ultraviolet radiation induced crosslinking on natural fiber and biomaterials / M. Fizur Rahman, Jahid M.M. Islam and Mubarak A. Khan (Institute of Radiation and Polymer Technology, Bangladesh Atomic Energy Commission, Bangladesh). , Mode of access: Internet via the GPO Access web site. Address as of 9/14/02: http://www.epa.gov/sunwise/doc/uvrad8-26.pdf; current access is available via PURL. , English
    Additional Edition: ISBN 1-63321-090-1
    Language: English
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  • 8
    UID:
    almahu_BV045483930
    ISBN: 978-1-119-43242-5
    Additional Edition: Erscheint auch als Online-Ausgabe, PDF ISBN 978-1-119-43235-7
    Additional Edition: Erscheint auch als Online-Ausgabe, EPUB ISBN 978-1-119-43243-2
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Apoptosis ; Aufsatzsammlung
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