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  • 1
    Online Resource
    Online Resource
    The human genome : a user's guide (2011)
    Amsterdam ; : Elsevier Academic Press,
    Details
    UID:
    almahu_9948025404202882
    Format: 1 online resource (600 p.)
    Edition: 3rd ed.
    ISBN: 1-78402-032-X , 1-282-95392-3 , 9786612953927 , 0-08-091865-4
    Content: Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Hum
    Note: First ed. by R. Scott Hawley and Catherine A. Mori. , Front Cover; The Human Genome; Copyright Page; Contents; Acknowledgments; Prologue: The Answer in a Nutshell; SECTION I: HOW GENES SPECIFY A TRAIT; Chapter 1 The Basics of Heredity: How Traits Are Passed Along in Families; 1.1 Mendel's Laws; 1.2 Selection: Artificial, Natural, and Sexual; 1.3 Human Genetic Diversity; 1.4 Human Dominant Inheritance; 1.5 Human Recessive Inheritance; 1.6 Complementation; 1.7 Epistasis and Pleiotropy; 1.8 Complex Syndromes; 1.9 One Man's Disease Is Another Man's Trait; Chapter 2 The Double Helix: How Cells Preserve Genetic Information; 2.1 Inside the Cell , 2.2 DNA: The Repository of Genetic Information2.3 DNA and the Double Helix; 2.4 DNA Replication; 2.5 Chromatin; 2.6 What Are Chromosomes?; 2.7 Euchromatin and Heterochromatin; 2.8 The Mitochondrial Chromosome: The ""Other Genome"" in the Human Genome; 2.9 DNA in vitro; SECTION II: HOW GENES FUNCTION; Chapter 3 The Central Dogma of Molecular Biology: How Cells Orchestrate the Use of Genetic Information; 3.1 What Is RNA?; 3.2 What Is RNA For?; 3.3 Transcription of RNA; 3.4 Orchestrating Expression; 3.5 Monitoring Gene Expression; 3.6 Interaction of Transcription Factors; 3.7 Inducible Genes , 3.8 Epigenetic Control of Gene Expression3.9 What Constitutes Normal?; Chapter 4 The Genetic Code: How the Cell Makes Proteins from Genetic Information Encoded in mRNA Molecules; 4.1 The Genetic Code; 4.2 Moving Things In and Out of the Nucleus; 4.3 The Central Dogma of Molecular Biology; 4.4 Translation; 4.5 Messenger RNA Structure; 4.6 Splicing; 4.7 Modular Genes; 4.8 What Are Proteins?; 4.9 Gene Products and Development; Chapter 5 We Are All Mutants: How Mutation Alters Function; 5.1 What Is a Mutation?; 5.2 The Process of Mutation; 5.3 How We Detect Mutations; 5.4 Basic Mutations , 5.5 Mutations in DNA Sequences that Regulate Gene Expression5.6 Copy Number Variation: Too Much or Too Little of a Good Thing; 5.7 Expanded Repeat Traits; 5.8 The Male Biological Clock; 5.9 Mutation Target Size; 5.10 Absent Essentials and Monkey Wrenches; SECTION III: HOW CHROMOSOMES MOVE; Chapter 6 Mitosis and Meiosis: How Cells Move Your Genes Around; 6.1 The Cell Cycle; 6.2 Mitosis; 6.3 Gametogenesis: What Is Meiosis Trying to Accomplish?; 6.4 Meiosis in Detail; 6.5 Mechanisms of Chromosome Pairing in Meiosis; 6.6 The Chromosomal Basis of Heredity , 6.7 Aneuploidy: When Too Much or Too Little Counts6.8 Uniparental Disomy; 6.9 Partial Aneuploidies; 6.10 The Female Biological Clock; Appendix 6.1 Failed Meiotic Segregation (Nondisjunction) as Proof of the Chromosome Theory of Heredity; Chapter 7 The Odd Couple: How the X and Y Chromosomes Break the Rules; 7.1 Passing the X and Y Chromosomes between Generations; 7.2 How Humans Cope with the Difference in Number of Sex Chromosomes between Males and Females; 7.3 How X Inactivation Works; 7.4 Skewed X Inactivation - When Most Cells Inactivate the Same X; 7.5 Genes that Escape X-Inactivation , 7.6 Reactivation of the Inactive X Chromosome in the Female Germline , English
    Additional Edition: ISBN 0-12-333445-4
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    HU Berlin
    FU Berlin
    Charité
  • 2
    Book
    Book
    The human genome : a user's guide (2005)
    Amsterdam [u.a.] :Elsevier, Acad. Press,
    Details
    UID:
    almafu_BV025302629
    Format: XI, 465 S. : , Ill., graph. Darst.
    Edition: 2. ed.
    ISBN: 0-12-333462-4
    Language: English
    Subjects: Biology
    RVK:
    WG 7000
    Keywords: Genom ; Mensch ; Humangenetik
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    Book
    HU Berlin get availability status
    FU Berlin get availability status
  • 3
    Online Resource
    Online Resource
    The human genome : a user's guide (2011)
    London [u.a.] : Elsevier
    Details
    UID:
    gbv_662494539
    Format: Online-Ressource (585 S.) , Ill. , 24 cm
    Edition: Online-Ausg. Amsterdam Elsevier Science & Technology 2011 Electronic reproduction; Mode of access: World Wide Web
    ISBN: 0123334454 , 9780123334459 , 0080918654 , 9780080918655
    Series Statement: Elsevier science in society series
    Content: As genetic issues play a growing role in health practice and public policy, new knowledge in this field will continue to have significant implications for individuals and society. Written to communicate sound and modern science in an accessible way for professionals and students with various levels of scientific background, this thoroughly revised edition of The Human Genome contributes to creating a genetically literate research and clinical population. With case studies and introductory vignettes which illustrate a wide range of perspectives on complex topics in genetics and updated material on the latest research on disease-specific topics, this book serves as a valuable resource for students and working professionals alike. * Full-color illustrations enhance and reinforce key concepts and themes * Chapters include interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers * Companion website includes self tests, electronic artwork, and a guide to additional web resources to meet the developing needs of health care professionals and researchers
    Note: Previous ed.: 2004 , Includes bibliographical references and index , PART I: HOW GENES SPECIFY A TRAITChapter 1: The Basics of Heredity: How Traits Are Passed Along in Families -- Chapter 2: The Double Helix: How Cells Preserve Genetic Information -- PART II: HOW GENES FUNCTION -- Chapter 3: The Central Dogma of Molecular Biology: How Cells Orchestrate the Use of Genetic Information -- Chapter 4: The Genetic Code: How the Cell Makes Proteins from Genetic Information Encoded in mRNA Molecules -- Chapter 5: We Are All Mutants: How Mutation Alters Function -- PART III: HOW CHROMOSOMES MOVE -- Chapter 6: Mitosis and Meiosis: How Cells Move Your Genes Around -- Chapter 7: The Odd Couple: How the X and Y Chromosomes Break the Rules -- PART IV: HOW GENES CONTRIBUTE TO COMPLEX TRAITS -- Chapter 8: Sex Determination: How Genes Determine a Developmental Choice -- Chapter 9: Complexity: How Traits Can Result from Combinations of Factors -- Chapter 10: The Multiple-Hit Hypothesis: How Genes Play a Role in Cancer -- PART V: HOW GENES ARE FOUND -- Chapter 11: The Gene Hunt: How Genetic Maps Are Built and Used -- Chapter 12: The Human Genome: How the Sequence Enables Genome-wide Studies -- PART VI: HOW GENES PLAY A ROLE IN TESTING AND TREATMENT -- Chapter 13: Genetic Testing and Screening: How Genotyping Can Offer Important Insights -- Chapter 14: Magic Bullets: How Gene-based Therapies Personalize Medicine -- Chapter 15: Fears, Faith, and Fantasies: How the Past and Present Shape the Future of Genomic Medicine. , PART I: HOW GENES SPECIFY A TRAIT -- Chapter 1: The Basics of Heredity: How Traits Are Passed Along in Families -- Chapter 2: The Double Helix: How Cells Preserve Genetic Information -- PART II: HOW GENES FUNCTION -- Chapter 3: The Central Dogma of Molecular Biology: How Cells Orchestrate the Use of Genetic Information -- Chapter 4: The Genetic Code: How the Cell Makes Proteins from Genetic Information Encoded in mRNA Molecules -- Chapter 5: We Are All Mutants: How Mutation Alters Function -- PART III: HOW CHROMOSOMES MOVE -- Chapter 6: Mitosis and Meiosis: How Cells Move Your Genes Around -- Chapter 7: The Odd Couple: How the X and Y Chromosomes Break the Rules -- PART IV: HOW GENES CONTRIBUTE TO COMPLEX TRAITS -- Chapter 8: Sex Determination: How Genes Determine a Developmental Choice -- Chapter 9: Complexity: How Traits Can Result from Combinations of Factors -- Chapter 10: The Multiple-Hit Hypothesis: How Genes Play a Role in Cancer -- PART V: HOW GENES ARE FOUND -- Chapter 11: The Gene Hunt: How Genetic Maps Are Built and Used -- Chapter 12: The Human Genome: How the Sequence Enables Genome-wide Studies -- PART VI: HOW GENES PLAY A ROLE IN TESTING AND TREATMENT -- Chapter 13: Genetic Testing and Screening: How Genotyping Can Offer Important Insights -- Chapter 14: Magic Bullets: How Gene-based Therapies Personalize Medicine -- Chapter 15: Fears, Faith, and Fantasies: How the Past and Present Shape the Future of Genomic Medicine. , PART I: HOW GENES SPECIFY A TRAITChapter 1: The Basics of Heredity: How Traits Are Passed Along in Families -- Chapter 2: The Double Helix: How Cells Preserve Genetic Information -- PART II: HOW GENES FUNCTION -- Chapter 3: The Central Dogma of Molecular Biology: How Cells Orchestrate the Use of Genetic Information -- Chapter 4: The Genetic Code: How the Cell Makes Proteins from Genetic Information Encoded in mRNA Molecules -- Chapter 5: We Are All Mutants: How Mutation Alters Function -- PART III: HOW CHROMOSOMES MOVE -- Chapter 6: Mitosis and Meiosis: How Cells Move Your Genes Around -- Chapter 7: The Odd Couple: How the X and Y Chromosomes Break the Rules -- PART IV: HOW GENES CONTRIBUTE TO COMPLEX TRAITS -- Chapter 8: Sex Determination: How Genes Determine a Developmental Choice -- Chapter 9: Complexity: How Traits Can Result from Combinations of Factors -- Chapter 10: The Multiple-Hit Hypothesis: How Genes Play a Role in Cancer -- PART V: HOW GENES ARE FOUND -- Chapter 11: The Gene Hunt: How Genetic Maps Are Built and Used -- Chapter 12: The Human Genome: How the Sequence Enables Genome-wide Studies -- PART VI: HOW GENES PLAY A ROLE IN TESTING AND TREATMENT -- Chapter 13: Genetic Testing and Screening: How Genotyping Can Offer Important Insights -- Chapter 14: Magic Bullets: How Gene-based Therapies Personalize Medicine -- Chapter 15: Fears, Faith, and Fantasies: How the Past and Present Shape the Future of Genomic Medicine. , Electronic reproduction; Mode of access: World Wide Web
    Additional Edition: ISBN 9780123334459
    Additional Edition: Erscheint auch als Druck-Ausgabe Human genome
    Language: English
    Subjects: Biology
    RVK:
    WG 7000
    Keywords: Mensch ; Genom ; Electronic books
    URL: Volltext
    URL: lizenzpflichtig
    URL: Volltext  (An electronic book accessible through the World Wide Web; click for information)
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
    UB Potsdam
  • 4
    Online Resource
    Online Resource
    The human genome : a user's guide (2005)
    Amsterdam :Elsevier Academic Press,
    Details
    UID:
    almafu_9959231031602883
    Format: 1 online resource (478 p.)
    Edition: 2nd ed.
    ISBN: 1-280-96680-7 , 1-283-73474-5 , 9786610966806 , 0-08-051885-0 , 0-08-047458-6
    Series Statement: Elsevier science in society series
    Content: This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is becoming a commonplace scientific discussion on the evening news. Join authors Julia Richards and Scott Hawley as they examine the biological foundations of humanity, looking at the science behind the sensation and the current and potential impact of the study of the genome on our society. The Human Genome, Second Ed
    Note: First ed. by R. Scott Hawley and Catherine A. Mori. , Front cover; Title page; Coyright page; Table of Contents; Acknowledgments; Preface; Section 1 THE BASICS OF HEREDITY; 1 SLAYING MOLECULAR DRAGONS: BRENDA'S TALE; 2 THE ANSWER IN A NUT SHELL: GENES, PROTEINS, AND THE BASIS OF LIFE; 3 MENDEL AND THE CONCEPT OF THE GENE; 4 HUMAN MENDELIAN GENETICS; 5 ONE MAN'S TRAIT IS ANOTHER MAN'S DISEASE; Section 2 THE CENTRAL DOGMA OF MOLECULAR BIOLOGY; 6 DNA: THE GENETIC ALPHABET; 7 THE CENTRAL DOGMA OF MOLECULAR BIOLOGY: HOW GENES ENCODE PROTEINS; 8 SPLICING THE MODULAR GENE; 9 ORCHESTRATING THE HUMAN GENOME; Section 3 HOW CHROMOSOMES MOVE , 10 SO WHAT ARE CHROMOSOMES ANYWAY?11 HOW CELLS MOVE YOUR GENES AROUND; 12 PASSING GENES BETWEEN GENERATIONS; 13 THE CHROMOSOMAL BASIS OF HEREDITY; Section 4 MUTATION; 14 ABSENT ESSENTIALS AND MONKEY WRENCHES; 15 HOW WE DETECT MUTATIONS; 16 WE ARE ALL MUTANTS; 17 WHAT CONSTITUTES NORMAL?; 18 MUTATIONS IN MAMMOTH GENES; 19 EXPANDED REPEAT TRAITS; Section 5 GENES, CHROMOSOMES, AND SEX; 20 THE X AND Y CHROMOSOMES: THE ODD COUPLE; 21 GENETICS OF SEX, GENDER, AND ORIENTATION; 22 ANEUPLOIDY: WHEN TOO MUCH OR TOO LITTLE COUNTS; Section 6 BREAKING THE RULES; 23 IMPRINTING , 24 IMITATING HEREDITY: ONE TRAIT, MANY CAUSESSection 7 THE HUMAN GENOME LANDSCAPE; 25 THE HUMAN GENOME PROJECT; 26 THERE'S CLONING AND THEN THERE'S CLONING; 27 THE HUMAN GENOME SEQUENCE; 28 FINDING GENES IN THE HUMAN GENOME; Section 8 COMPLEX AND HETEROGENEOUS TRAITS; 29 GENOTYPE PHENOTYPE CORRELATIONS; 30 HOW COMPLEX CAN IT GET?; 31 QUANTITATIVE TRAITS; 32 THE MAOA GENE: IS THERE A GENETIC BASIS FOR CRIMINALITY?; 33 THE MULTIPLE-HIT HYPOTHESIS: THE GENETICS OF CANCER; Section 9 GENETIC TESTING AND THERAPY; 34 GENETIC TESTING AND SCREENING; 35 MAGIC BULLETS: THE POTENTIAL FOR GENE THERAPY , Section 10 FEARS, FAITH, AND FANTASIES36 HEROES AMONG US; 37 FEARS, FAITH, AND FANTASIES; Credits; Index , English
    Additional Edition: ISBN 0-12-333462-4
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    FU Berlin
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