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  • 1
    UID:
    edochu_18452_11996
    ISSN: 1619-3997 , 1619-3997
    Content: Objectives: To investigate whether a near infrared spectroscopy (NIRS) system is useful for evaluation of the placental function in cases of fetal growth restriction (FGR). Methods: Subjects included 282 delivered neonates of appropriate for gestational age (AGA) and 44 small for gestational age (SGA) babies. The measurement of the concentration of oxyhemoglobin (HbO2) and deoxyhemoglobin (HHb) was conducted using transabdominal NIRS targeting the placenta at around 20 weeks, 30 weeks and after 36 weeks of gestation and calculated tissue oxygen indexes (TOI=HbO2/total Hb). We correlated between TOIs and causes of FGR. Results: TOIs measured immediately before delivery in the SGA group with severe pre-eclampsia (79.2±3.8 (%±standard deviation (SD); P=0.002)) and placental abnormalities (78.2±3.6; P=0.043) were higher than in the AGA group (74.0±4.5). TOIs in the SGA group with umbilical cord abnormalities were lower (69.7±7.7; P=0.024) than in the AGA group. Conclusion: NIRS might provide information about blood oxygen level of the intervillous space and thus explain the cause of FGR.
    Content: Peer Reviewed
    In: Journal of Perinatal Medicine, : de Gruyter, 2010, 38,2009,1, Seiten 29-32, 1619-3997
    Language: Undetermined
    URL: Volltext  (kostenfrei)
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  • 2
    UID:
    edochu_18452_13210
    ISSN: 1619-3997 , 1619-3997
    Content: Aim: To study the relation of umbilical cord insertion (CI) site in early gestation and placental development from the chorion villosum. Methods: We ultrasonically measured the distance between the internal cervical Os and the CI site (CID), the distance between the internal cervical Os and lower placenta edge (PLD), and placental thickness at early (10–12 weeks) and mid-gestation (18–20 weeks). Results: CID in early gestation (CID-Early) correlated with CID in mid-gestation (r2=0.171; P<0.01). CID-Early correlated with PLD in mid-gestation (r2=0.093; P<0.01). Thickness of chorion villosum or placenta in early gestation did not correlate with that at mid-gestation. Increasing thickness of placenta was significantly higher in long CID-Early (≥20 mm) cases than short cases (<20 mm) (P<0.05). Conclusions: The process of placental development and the placental location are affected by CI location at early gestation, and suggests that this process might be affected by poor blood supply from the low uterine segment when CI site is close to the internal cervical Os.
    Content: Peer Reviewed
    In: Journal of Perinatal Medicine, : de Gruyter, 2009, 37,2009,5, Seiten 481-485, 1619-3997
    Language: Undetermined
    URL: Volltext  (kostenfrei)
    Library Location Call Number Volume/Issue/Year Availability
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