Format:
1 Online-Ressource (121 Seiten, 3104 KB)
,
Illustrationen, Diagramme
Content:
Various ways of preparing enantiomerically pure 2-amino[6]helicene derivatives were explored. Ni(0) mediated cyclotrimerization of enantiopure triynes provided (M)- and (P)-7,8-bis(p-tolyl)hexahelicene-2-amine in 〉99% ee as well as its benzoderivative in 〉99% ee. The stereocontrol was found to be inefficient for a 2- aminobenzo[6]helicene congener with an embedded five-membered ring. Helically chiral imidazolium salts bearing one or two helicene moieties have been synthesized and applied in enantioselective [2+2+2] cyclotrimerization catalyzed by an in situ formed Ni(0)-NHC complex. The synthesis of the first helically chiral Pd- and Ru-NHC complexes and their application in enantioselective catalysis was demonstrated. The latter shows promising results in enantioselective olefin metathesis reactions. A mechanistic proposal for asymmetric ring closing metathesis is provided.
Note:
Dissertation Universität Potsdam 2018
Additional Edition:
Erscheint auch als Druck-Ausgabe Karras, Manfred Synthesis of enantiomerically pure helical aromatics such as NHC ligands and their use in asymmetric catalysis Potsdam, 2018
Language:
English
Keywords:
Asymmetrische Synthese
;
Katalyse
;
Heterocyclische Carbene
;
Hochschulschrift
URN:
urn:nbn:de:kobv:517-opus4-421497
URL:
Volltext
(kostenfrei)
URL:
https://nbn-resolving.org/urn:nbn:de:kobv:517-opus4-421497
URL:
https://d-nb.info/1218404248/34
Author information:
Schmidt, Bernd 1967-
Bookmarklink