UID:
almahu_9949737678002882
Format:
1 online resource (333 p.)
ISBN:
1-5231-0476-7
,
1-78262-241-1
Series Statement:
Issues in toxicology ; 26
Content:
This book provides an up-to-date treatise on the on-going research into the toxicology of chemical warfare agents, the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning.
Note:
Description based upon print version of record.
,
Cover; Chemical Warfare Toxicology Volume 1: Fundamental Aspects; Preface; References to Material in the National Archives; Contents; Chapter 1 - Development, Historical Use and Properties of Chemical Warfare Agents; 1.1 Introduction; 1.2 Brief History of CW; 1.2.1 Prior to 1914; 1.2.2 The 1914-18 War (WWI); 1.2.2.1 Overview; 1.2.2.2 Irritants; 1.2.2.3 Chlorine; 1.2.2.4 Phosgene; 1.2.2.5 Sulfur Mustard; 1.2.2.6 Other Agents; 1.2.3 The Inter-War Years; 1.2.4 The 1939-1945 War (WWII); 1.2.5 Post WWII and the Cold War Years; 1.2.6 The Middle East; 1.2.7 Terrorism
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1.2.8 Chemical Weapons Convention1.3 Classification, Properties and Modes of Use of CW Agents; 1.3.1 Classification; 1.3.2 Physicochemical Properties; 1.3.2.1 Gaseous and Liquid Agents; 1.3.2.2 Solid Agents; 1.3.3 Ease of Production; 1.4 Main Classes of Chemical Agents; 1.4.1 Lung Injurants (Choking Agents); 1.4.1.1 Chlorine; 1.4.1.2 Phosgene and Diphosgene; 1.4.1.3 Perfluoroisobutene; 1.4.2 Blood Agents; 1.4.2.1 Hydrogen Cyanide; 1.4.2.2 Cyanogen Chloride; 1.4.3 Vesicants (Blister Agents); 1.4.3.1 Sulfur Mustard; 1.4.3.2 Nitrogen Mustards; 1.4.3.3 Lewisite; 1.4.4 Nerve Agents
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1.4.4.1 Tabun and DFP1.4.4.2 Sarin, Soman, Cyclosarin and 2-Methyl GF; 1.4.4.3 V Agents; 1.4.4.4 Other Nerve Agents; 1.4.5 Riot Control Agents; 1.4.6 Incapacitants; 1.4.7 Future Developments; References; Chapter 2 - Toxicology of Vesicants; 2.1 Introduction; 2.2 Sulfur Mustard; 2.2.1 Mechanism of Action; 2.2.1.1 Chemical Reactivity; 2.2.1.2 Alterations to DNA; 2.2.1.3 Alterations to Other Cellular Components and Processes; 2.2.2 Toxicokinetics, Metabolism and Distribution; 2.2.2.1 Studies in Animals
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2.2.2.2.2 Other Routes of Exposure.No systematic studies describe the kinetics of SM following other routes of exposure in humans. In part...2.2.2.3 In vitro Studies; 2.2.3 Acute Toxicity; 2.2.3.1 Studies in Animals; 2.2.3.1.1 Oral Exposure.There are few reports on the oral toxicity of SM. In one study, the oral lethal dose, 50% (LD50) of SM [administer...; 2.2.3.1.2 Dermal Exposure.Since the first research efforts in 1917-1918, a large range of animal species have been exposed to SM liquid an...
Additional Edition:
ISBN 1-84973-969-2
Language:
English
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