Kooperativer Bibliotheksverbund

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Format: 1 streaming video file (47 min.) : , digital, mono, SWF file, sound, color , 004637

Content: Audio-visual presentation : Pregnancy and the immune system ; SLE flares during pregnancy ; Gestational outcome in SLE ; Predictors of obstetrical and neonatal complications in SLE ; Autoantibodies that can affect pregnancy outcome: antiphospholipid antibodies ; Obstetrical complications and newborns outcome in antiphospholipid syndrome ; Autoantibodies that can affect pregnancy outcome: anti-Ro/SS-A antibodies ; Neonatal lupus ; Congenital heart block and in utero exposure to dexamethasone.

Note: Retrieved April 7, 2024, from https://hstalks.com/bs/200/. , Introduction -- Pregnancy and the immune system -- SLE and flares during pregnancy -- Pregnancies and patients studied -- Flare definition applied in pregnancy -- Physician judgement and disease activity index -- Flare definition -- Timing of SLE flares in pregnancy -- Flare frequency by timing of pregnancy -- ECLAM score / estrogen levels during pregnancy -- Can we know flare occurrences in advance ? -- Significant predictors of flares -- Pregnant women with SLE can have flares -- Gestational outcome in SLE -- Impact of lupus activity on obstetric outcome -- Gestational outcome in SLE: example -- Gestational outcome in renal SLE -- Identifying patients with a high risk of baby loss -- Predictors of adverse pregnancy outcome -- Predictors of obstetrical /neonatal complications -- Factors that predict prematurity and preeclampsia -- Autoantibodies that affect pregnancy outcome -- Antiphospholipid (APL) antibody definition -- Antiphospholipid (APL) antibody associations -- Beta-2 glycoprotein I (beta-2GPI) -- Two-hit theory in APS -- Placenta: the target of aPL -- Beta-2GPI binds the trophoblast cell membranes -- Revised classification for APS syndrome -- Antiphospholipid antibodies and autoimmunity -- APS is treatable cause of prgnancy loss -- Obstetrical complications -- Newborns from mothers with primary APS (1) -- Newborns from mothers with primary APS (2) -- Thrombosis in the offspring of APS patients -- Transplacental passage of IgG aPL (1) -- Transplacental passage of IgG aPL (2) -- aPL in 12 month old babies -- The influence on fetal development -- Mental developement and maternal autoAbs (1) -- Mental developement and maternal autoAbs (2) -- Clinical success and open questions -- Register of infants from mothers with APS -- IgG isotope can influence pregnancy -- Ro complex -- Anti-Ro/anti-La and autoimmunity -- Anti Ro/SS-A and gestational outcome -- Neonatal lupus model -- Anti Ro/SS-A and congenital heart block (CHB) -- Proposed mechanism of cardiac damage -- The diagnosis of CHB -- In utero detection of first-degree heart block -- Management of CHB -- Antenatal and postnatal exposure to DEX -- 11 CHB children with/without exposure to DEX -- T-cell evaluation in eight DEX exposed children -- Heteroduplex analysis on TCRBV chains -- Oligoclonal expansions of TCR repertoire -- Alessa - case study -- Second pregnancy - case study -- Acknowledgements and contacts.

Language: English