Format:
Online-Ressource (X, 108 p. 65 illus, online resource)
ISBN:
9783540396178
Series Statement:
Advances in Anatomy Embryology and Cell Biology 191
Content:
The authors' results show that ischemia differentially activates endogenous neural precursors residing in diverse locations of the adult primate central nervous system. A limited endogenous potential for postischemic neuronal repair exists in neocortex and striatum, but not in the hippocampus proper of the adult macaque monkey brain. The presence of putative parenchymal progenitors and of sustained progenitors in germinative centers opens novel possibilities for precursor cell recruitment.
Content:
The authors` results show that ischemia differentially activates endogenous neural precursors residing in diverse locations of the adult primate central nervous system. A limited endogenous potential for postischemic neuronal repair exists in neocortex and striatum, but not in the hippocampus proper of the adult macaque monkey brain. The presence of putative parenchymal progenitors and of sustained progenitors in germinative centers opens novel possibilities for precursor cell recruitment to sites of injury. The molecular manipulation of this process may advance the ability to effectively apply brain progenitor cells in the treatment of human neurological diseases.
Note:
Includes bibliographical references (p. [97]-106) and indexes
,
Introduction; Materials and Methods; Results; Discussion; Summary
Additional Edition:
ISBN 9783540396130
Additional Edition:
Erscheint auch als Druck-Ausgabe Tonchev, Anton B. Distribution and phenotype of proliferating cells in the forebrain of adult Macaque monkeys after transient global cerebral ischemia Berlin : Springer, 2007 ISBN 9783540396130
Additional Edition:
ISBN 3540396136
Language:
English
Subjects:
Medicine
Keywords:
Hirnkrankheit
;
Ischämie
;
Vorderhirn
;
Proliferation
;
Tiermodell
;
Hirnkrankheit
;
Proliferation
;
Tiermodell
;
Ischämie
;
Vorderhirn
DOI:
10.1007/978-3-540-39617-8
URL:
Volltext
(lizenzpflichtig)
Author information:
Yamashima, Tetsumori
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