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  • 1
    UID:
    almahu_BV045537592
    Format: 1 Online-Ressource (xi, 349 Seiten).
    ISBN: 978-981-132-977-7
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-132-976-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-132-978-4
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (URL des Erstveröffentlichers)
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    New York, NY : Springer New York
    UID:
    gbv_1657963462
    Format: Online-Ressource (XII, 494 p. 115 illus., 53 illus. in color, online resource)
    ISBN: 9781493906796
    Series Statement: Oxidative Stress in Applied Basic Research and Clinical Practice
    Content: This volume examines the role of oxidative stress in the pathology of numerous pediatric disorders. It covers a wide range of topics including the chemistry and biology of reactive oxygen species and nitric oxide, molecular biology of the enzymes generating these species, clinically useful biomarkers for evaluating oxidative stress status in humans, and the pathophysiology, clinical course and management of a variety of pediatric disorders, among others. The book also describes current diagnostic tools, laboratory methods and technology for treatment and prevention of pediatric disorders. It explores emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents. Written by an international team of experts in both pediatrics and free radical and antioxidant research, Studies on Pediatric Disorders is an invaluable addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series
    Note: Description based upon print version of record , Oxygen in health and diseaseReactive oxygen species and nitric oxide in vascular function -- Nitrite pathway: Another important nitric oxide production system -- Nitric oxide and beyond: New insights and therapies for endothelial targeting -- Multifunctional roles of nitric oxide in neurons -- Oxidative stress biomarkers: Future perspectives -- Urinary clinical biomarkers in critical care -- Rapid diagnostic tests for oxidative stress status -- Analytical procedures for nitrative/nitrosative stress -- Animal models of enhanced oxidative stress -- Antioxidant supplementation and therapies -- Edaravone therapy -- Melatonin therapy -- Thioredoxin therapy -- Allergic and immunological disorders -- Cardiac disorders -- Environmental pollution and health consequences -- Gastrointestinal disorders -- Genetic disorders -- Growth, puberty and nutritional disturbances -- Hematologic disorders -- Infectious and inflammatory disorders -- Metabolic disorders -- Neurological disorders -- Renal disorders -- Respiratory disorders -- Trauma -- Vascular disorders.
    Additional Edition: ISBN 9781493906789
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-149-390-678-9
    Language: English
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 3
    UID:
    edoccha_9959090529202883
    Format: 1 online resource (XI, 349 p. 167 illus., 113 illus. in color.)
    Edition: 1st ed. 2019.
    ISBN: 981-13-2976-1
    Content: This textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.
    Note: Part1. Metabolic Disorders -- 1. Citrin Deficiency -- 2. Aspartoacylase Deficiency (Canavan Disease, N-Acetylaspartic Aciduria) -- 3. Prominent Insulin Resistance in Congenital Generalized Lipoatrophy -- 4. Fabry Disease -- 5. Familial Hypercholesterolemia -- 6. Gaucher Disease -- 7. Heme Oxygenase-1 Deficiency -- 8. The Homocystinurias -- 9. Hypophosphatasia -- 10. Phenylketonuria -- 11. Triglyceride Deposit Cardiomyovasculopathy -- 12. Urea Cycle Disorders -- 13. Wilson Disease -- Part2. Genetics -- 14. Achondroplasia -- 15. Acute Myeloid Leukemia: Mutations Blocking Differentiation Lead to Distinct Leukemic Subtypes -- 16. α1-Antitrypsin Deficiency -- 17. Hereditary Anticoagulant Deficiencies -- 18. Cherubism -- 19. Cancer and Excess Iron -- 20. Fukuyama Congenital Muscular Dystrophy and Related Diseases -- 21. Hereditary Proteinuric Glomerular Disorders -- 22. Marfan Syndrome -- 23. When Materials Are at Fault: The Skeletal Collagens, Osteogenesis Imperfecta and Chondrodysplasias -- Part3. Others -- 24. Acute Kidney Injury: Transition to Chronic Kidney Disease -- 25. Type I Interferonopathies: Common Pathological Features Between Congenital Infections and Genetic Disorders -- 26. Epilepsy -- 27. Hemophagocytic Lymphohistiocytosis -- 28. Hepatitis C Virus Infection -- 29. Substance Abuse Emergencies.
    Additional Edition: ISBN 981-13-2977-X
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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