Kooperativer Bibliotheksverbund

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Format: 1 online resource (xxi, 390 pages) : , illustrations

ISBN: 3527603840 , 9783527603848 , 3527603751 , 9783527603756 , 1280519487 , 9781280519482

Content: Nitric oxide is a highly potent regulatory molecule with great pharmaceutical potential. This handbook fills a real gap in combining the chemistry of nitric oxide releasing substances with their practical applications in biology and drug design. It covers all classes of nitric oxide donors, from organic nitrates to nitroso compounds, guanidines and metal-NO complexes. In addition to a detailed treatment of the chemistry of NO donors, numerous examples of successful diagnostic and pharmacological applications are discussed, as well as further therapeutic targets for these substances.

Note: Nitric Oxide Donors; Contents; Preface; List of Contributors; Part 1 Chemistry of NO Donors; 1 NO and NO Donors; 2 Organic Nitrates and Nitrites; 3 N-Nitroso Compounds; 4 The Role of S-Nitrosothiols in the Biological Milieu; 5 Metal-NO complexes: Structures, Syntheses, Properties and NO-releasing Mechanisms; 6 The NO-releasing Heterocycles; 7 C-Nitroso Compounds, Oximes, N-Hydroxyguanidines and N-Hydroxyureas; Part 2 NO Donors' Applications in Biological Research; 8 Vasodilators for Biological Research; 9 NO Donors as Antiplatelet Agents; 10 Control of NO Production.

Additional Edition: Print version: Nitric oxide donors. Weinheim : Wiley-VCH, ©2005 ISBN 3527310150

Language: English

Keywords: Electronic books. ; Electronic books. ; Electronic books.

DOI: 10.1002/3527603751

URL: https://onlinelibrary.wiley.com/doi/book/10.1002/3527603751

URL: https://onlinelibrary.wiley.com/doi/book/10.1002/3527603751

URL: https://onlinelibrary.wiley.com/doi/book/10.1002/3527603751

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Format: 1 Online-Ressource (223 pages) , illustrations

ISBN: 9780841237919

Series Statement: ACS symposium series 1346

Note: Distributed in print by Oxford University Press , Includes bibliographical references and index , Recent Advancements in Arrayed Technologies and Emerging Themes in the Identification of Glycan-Protein Interactions / , Insights into Antibody-Carbohydrate Recognition from Neoglycoprotein Microarrays / , Generation of a Heparan Sulfate Mutant Cell Library and Its Application to Determine the Structure-Function Relationship of Heparan Sulfate in Facilitating FGF2-FGFR1 Signaling / , Polyvalent Glycan-Quantum Dots as Multifunctional Structural Probes for Multivalent Lectin-Carbohydrate Interactions / , Automated Identification of Lectin Fine Specificities from Glycan-Array Data / , Label-Free Biosensors for Studying Carbohydrate-Protein Interaction / , Sketching the Glycan Hallmark of Intact Cells Using Lectin Microarray / , Methods to Investigate Innate Immune Receptors and Their Carbohydrate-Based Ligands / , Morphogenesis of the Mammalian Tectorial Membrane: Unveiling the Surface Roles of a Matrix Organizer, Alpha Tectorin / , Mass Spectrometric Analysis of Protein Glycosylation / , Editors’ Biographies /

Additional Edition: ISBN 9780841298989

Additional Edition: Erscheint auch als ISBN 9780841298989

Language: English

DOI: 10.1021/bk-2020-1346

URL: lizenzpflichtig

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Format: 1 Online-Ressource (195 pages) , illustrations

ISBN: 9780841219786

Series Statement: ACS symposium series 873

Note: Distributed in print by Oxford University Press , Includes bibliographical references and index , Approaches to the Enzymatic Carbohydrate Synthesis / , Exploring Carbohydrate Diversity through Automated Synthesis / , Glycosynthesis for Drug Discovery: Globo H Synthesis by OPopS / , Probing the Antigenic Diversity of Sugar Chains / , Chemoenzymatic Synthesis of Lactosamine and (α2→3)Sialylated Lactosamine Building Blocks / , Synthesis of Bioactive Glycopeptides through Endoglycosidase-Catalyzed Transglycosylation / , Strategies for Synthesis of an Oligosaccharide Library Using a Chemoenzymatic Approach / , Artificial Golgi Apparatus: Direct Monitoring of Glycosylation Reactions on Automated Glycosynthesizer / , Sugar Engineering with Glycosaminoglycan Synthases / , Production of Oligosaccharides Using Engineered Bacteria: Engineering of Exopolysaccharides from Lactic Acid Bacteria / , Production of Oligosaccharides by Coupling Engineered Bacteria / , Synthesis of Glycoconjugates through Biosynthesis Pathway Engineering /

Additional Edition: ISBN 9780841238657

Additional Edition: ISBN 0841238650

Additional Edition: Erscheint auch als ISBN 9780841238657

Additional Edition: Erscheint auch als ISBN 0841238650

Language: English

DOI: 10.1021/bk-2004-0873

URL: lizenzpflichtig

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Format: 1 Online-Ressource (344 pages) , illustrations

ISBN: 9780841221338

Series Statement: ACS symposium series 990

Note: "The 2-day Chemical Glycobiology Symposium in the 232rd American Chemical Society National Meeting in San Francisco ... "--Preface , Distributed in print by Oxford University Press , Includes bibliographical references and index , De Novo Synthesis in Carbohydrate Chemistry: From Furans to Monosaccharides and Oligosaccharides / , Chemical Syntheses of Hyaluronic Acid Oligosaccharides / , Synthetic Efforts in Preparations of Components of the Bacterial Cell Wall / , New Glycosyl Thio-carboamino Peptides as New Tools for Glycobiology / , Chemoenzymatic Synthesis of Sialosides and Their Applications / , Convergent Chemoenzymatic Synthesis of Complex N-Glycopeptides / , Synthesis of Glycolipid Antigens / , Chemical Glycobiology of Glycosphingolipids / , Clinical Outcome of Breast and Ovarian Cancer Patients Treated after High-Dose Chemotherapy and Autologous Stem Cell Rescue with Theratope (STn-KLH) Cancer Vaccine: Theratope (STn-KLH) Cancer Vaccine following Autologous Transplant / , Synthesis and Evaluation of Anticancer Vaccine Candidates, C-Glycoside Analogs of STn and PSA / , An Automated Method for Determining Glycosylation and Site Diversity in Glycoproteins / , Chemical Approaches to Glycobiology / , Automated Solution-Phase Oligosaccharide Synthesis and Carbohydrate Microarrays: Development of Fluorous-Based Tools for Glycomics / , Polypeptide-Based Glycopolymers for the Study of Multivalent Binding Events /

Additional Edition: ISBN 9780841274402

Additional Edition: ISBN 0841274401

Additional Edition: Erscheint auch als ISBN 9780841274402

Additional Edition: Erscheint auch als ISBN 0841274401

Language: English

DOI: 10.1021/bk-2008-0990

URL: lizenzpflichtig

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Format: XXI, 390 Seiten , graph. Darst. , 25 cm

Edition: 1

ISBN: 3527310150

Note: Literaturangaben , Text engl.

Language: English

Keywords: Stickstoffmonoxidradikal ; Donorgruppe ; Arzneimitteldesign

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Format: 1 Online-Ressource (xvii, 469 Seiten) , Illustrationen, Diagramme

ISBN: 9781788016575 , 9781788017770

Series Statement: Chemical biology 11

Content: Introduction: Glycome and the Glyco-toolbox; Methodologies in Chemical Syntheses of Carbohydrates; Synthetically Useful Glycosyltransferases for the Access of Mammalian Glycomes; Chemical Synthesis of N-Glycans; Chemoenzymatic Synthesis of N-glycans; Chemoenzymatic Synthesis of #xF061;-Dystroglycan O-Mannose Glycans; Chemical Synthesis of Glycopeptides and Glycoproteins; Synthesis of Chondroitin Sulfate Oligosaccharides and Chondroitin Sulfate Glycopeptides; Chemoenzymatic Synthesis of Heparan Sulfate and Heparin; One-pot Multienzyme (OPME) Synthesis of Glycosphingolipids (GSLs); Enzymatic and Chemoenzymatic Synthesis of Human Milk Oligosaccharides (HMOS); Synthesis of Marine Polysaccharides/Oligosaccharides and Their Derivatives; Glycan Production by Bacterial Fermentation; Solid-phase Glycan Synthesis; Reverse Synthesis of Natural Glycans; Novel Technologies for Quantitative O-glycomics and Amplification/Preparation of Cellular O-glycans; Current Stage of Commercially Available Glycans to Support Realization of Biologic Drugs; Glycan Microarrays with Semi-synthetic Neoglycoconjugate Probes in Understanding Glycobiology; Current Stage of Commercial Glycan Microarrays

Content: Synthetic Glycomes aims to provide a comprehensive review of the current state of the synthetic glycome, synthetic strategies toward generating glycans with comprehensive structures, as well as the glycoarrays to unveil the glycan functions

Additional Edition: ISBN 9781788011648

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 1788011643

Additional Edition: ISBN 9781788011648

Language: English

DOI: 10.1039/9781788016575

URL: Volltext

URL: Volltext

URL: lizenzpflichtig

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Format: x, 213 Seiten : , Illustrationen, Diagramme.

ISBN: 978-0-8412-9898-9

Series Statement: ACS symposium series 1346

Additional Edition: Erscheint auch als Online-Ausgabe ISBN 978-0-8412-3791-9

Language: English

Subjects: Biology

Keywords: Glykoproteine ; Polysaccharide ; Zellkontakt ; Zellkommunikation ; Konferenzschrift

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032864710&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

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Format: XVI, 682 S , graph. Darst

ISBN: 0824705386

Note: Includes bibliographical references and index

Language: English

Subjects: Chemistry/Pharmacy , Biology

Keywords: Glykokonjugate ; Organische Synthese ; Physiologische Chemie ; Aufsatzsammlung

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Format: 1 online resource

ISBN: 9781788017770 , 1788017773 , 9781788016575 , 1788016572

Series Statement: Chemical biology

Content: Synthetic Glycomes aims to provide a comprehensive review of the current state of the synthetic glycome, synthetic strategies toward generating glycans with comprehensive structures, as well as the glycoarrays to unveil the glycan functions.

Note: Includes index. , Title from title details screen. , Introduction: Glycome and the Glyco-toolbox; Methodologies in Chemical Syntheses of Carbohydrates; Synthetically Useful Glycosyltransferases for the Access of Mammalian Glycomes; Chemical Synthesis of N-Glycans; Chemoenzymatic Synthesis of N-glycans; Chemoenzymatic Synthesis of #xF061;-Dystroglycan O-Mannose Glycans; Chemical Synthesis of Glycopeptides and Glycoproteins; Synthesis of Chondroitin Sulfate Oligosaccharides and Chondroitin Sulfate Glycopeptides; Chemoenzymatic Synthesis of Heparan Sulfate and Heparin; One-pot Multienzyme (OPME) Synthesis of Glycosphingolipids (GSLs); Enzymatic and Chemoenzymatic Synthesis of Human Milk Oligosaccharides (HMOS); Synthesis of Marine Polysaccharides/Oligosaccharides and Their Derivatives; Glycan Production by Bacterial Fermentation; Solid-phase Glycan Synthesis; Reverse Synthesis of Natural Glycans; Novel Technologies for Quantitative O-glycomics and Amplification/Preparation of Cellular O-glycans; Current Stage of Commercially Available Glycans to Support Realization of Biologic Drugs; Glycan Microarrays with Semi-synthetic Neoglycoconjugate Probes in Understanding Glycobiology; Current Stage of Commercial Glycan Microarrays

Additional Edition: Print version: ISBN 1788011643

Additional Edition: ISBN 9781788011648

Language: English

Keywords: Electronic books.

URL: https://doi.org/10.1039/9781788016575