Kooperativer Bibliotheksverbund

UID:

Format: 1 Online-Ressource (XXII, 338 Seiten) : , 124 Illustrationen, 116 Illustrationen (farbig).

ISBN: 978-981-13-2267-9

Note: Titelrückseite: "Jointly published with Peking University Press, Beijing, China"

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-13-2266-2

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-132-268-6

Language: English

Subjects: Economics

Keywords: Technologieunternehmen ; Wirtschaftsentwicklung

DOI: 10.1007/978-981-13-2267-9

URL: Volltext  (URL des Erstveröffentlichers)

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (VIII, 437 p. 85 illus., 59 illus. in color).

ISBN: 978-94-024-1045-7

Series Statement: Translational Medicine Research

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-94-024-1043-3

Language: English

DOI: 10.1007/978-94-024-1045-7

URL: Volltext  (URL des Erstveröffentlichers)

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029661876&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

URL: Volltext  (URL des Erstveröffentlichers)

URL: Inhaltsverzeichnis

UID:

Format: 1 online resource (382 pages) : , illustrations

ISBN: 0-12-812745-7

Note: Front Cover -- Systems Biology and its Application in TCM Formulas Research -- Copyright -- Contents -- Contributors -- Introduction -- Section 1: Ideas and Methods for the Modern Research of TCM Formulas -- Chapter 1: Strategy for Modern Research of Traditional Chinese Medicine Formulae -- 1.1. Current Research on TCM Formulae -- 1.2. Principles for the Study of TCM Formulae -- 1.2.1. Holism and Reductionism -- 1.2.2. Macro- and Microstudies -- 1.2.3. In Vitro and in vivo Studies -- 1.3. Modern TCM Formulae Research -- 1.3.1. Research on Therapeutic Materials Basis -- 1.3.2. Modern Pharmacology -- 1.3.2.1. Top-Down: Holistic Pharmacology and Active Components Screening -- 1.3.2.2. Bottom-Up: Pharmacological Evaluation of Key Active Components and Multicomponent Compatibility -- 1.3.3. Systems Biology -- 1.3.3.1. Genomics -- 1.3.3.2. Proteomics -- 1.3.3.3. Metabolomics -- 1.3.3.4. Epigenomics -- 1.3.3.5. Metagenomics -- 1.4. Network Biology and TCM Network Pharmacology -- References -- Chapter 2: Theories and Methods for the Evaluation of the Pharmacodynamic Material Basis of Traditional Chinese Medicine -- 2.1. The Development of Research on the Pharmacodynamic Material Basis of TCM -- 2.2. New Methods for the Study of the Pharmacodynamic Material Basis of TCM -- 2.2.1. Combined Chemical Technologies for the Study of TCM -- 2.2.2. Serum Pharmacology and Serum Pharmacochemistry Method -- 2.2.3. Analysis of Spectrum-Effect Relationships -- 2.2.4. HTS of Multiple Targets -- 2.2.5. Molecular Biological Chromatography Technique -- 2.2.6. Metabolism Method -- 2.2.7. System Biology Method -- References -- Chapter 3: Application of Systems Biology in the Research of TCM Formulae -- Abstract -- Keywords -- 3.1. Omics in Systems Biology -- 3.1.1. Genomics -- 3.1.1.1. Pharmacogenomics -- 3.1.1.2. Metagenomics -- 3.1.1.3. Epigenomics. , 3.1.2. Transcriptomics -- 3.1.3. Proteomics -- 3.1.3.1. Phosphoproteomics -- 3.1.3.2. Glycoproteomics -- 3.1.3.3. Chemoproteomics -- 3.1.4. Metabolomics -- 3.1.4.1. Pharmacometabolomics -- 3.1.4.2. Lipidomics -- 3.1.5. Other "Omics" Technologies -- 3.1.5.1. Phenomics -- 3.1.5.2. Immunomics -- 3.1.5.3. Metallomics -- 3.1.5.4. Cytomics -- 3.1.5.5. Ionomics -- 3.1.5.6. Interactomics -- 3.2. Application of Systems Biology in the Research of TCM Formulae -- 3.2.1. Action Mechanisms of TCM Formulae -- 3.2.2. The Concept of a Syndrome in TCM -- 3.2.3. Active Component Compatibility (or Synergy) in TCM Formulae -- 3.2.4. Pharmacokinetic Studies of TCM Formulae -- 3.2.5. Discovery and Development of TCM-Based New Drugs -- References -- Chapter 4: Network Pharmacology in the Study of TCM Formulae -- 4.1. Identification of Therapeutically Effective TCM Compounds -- 4.2. Identification of the Targets of Active TCM Compounds -- 4.2.1. Proteomic Technologies -- 4.2.2. Computational Predictions -- 4.2.3. Database Searching -- 4.3. Identification of Disease-Associated Genes and Construction of Disease-Related Networks -- 4.3.1. Identification of Disease-Associated Genes -- 4.3.2. Construction of Disease Networks -- 4.4. Identification of TCM Formulae-Regulated Signaling Pathways and the Evaluation of the TCM Formulae on Disease-Relate ... -- 4.4.1. Identification of Drug Target-Rich Pathways -- 4.4.2. Construction of Subnetworks Influenced by Drugs and Evaluation of the Effects of TCM Formulae -- 4.4.2.1. Heuristic Algorithm -- 4.4.2.2. Steiner Minimum Tree Algorithm -- 4.4.2.3. Network Proximity Scoring Algorithm -- 4.5. Case Studies -- 4.5.1. Case Study 1: Antidepressant Activity of St. John's Wort -- 4.5.2. Case Study 2: The Effect of Realgar-Indigo Naturalis Formula on Acute Promyelocytic Leukemia -- 4.6. Perspectives -- References. , Chapter 5: Application of Intestinal Flora in the Study of TCM Formulae -- 5.1. Classification of Intestinal Flora -- 5.2. The Relationship Between Intestinal Dysbacteriosis and Disease -- 5.3. Influence of Intestinal Bacterial Metabolism on Effective TCM Ingredients -- 5.3.1. Enhanced Absorption and Elevated Efficacy of Intestinal Flora Metabolism on TCM Ingredients -- 5.3.2. Attenuated or Increased Toxicity of Intestinal Flora on TCM Ingredients -- 5.3.3. Confirmation of the Rationality of TCM Synergy and Compatibility -- 5.4. Modulation of the Intestinal Flora by TCM -- 5.4.1. Regulation of Intestinal Flora Composition by TCM -- 5.4.1.1. Effects of a Single Herb or Single Extract on Intestinal Flora Composition -- 5.4.1.2. Effects of TCM Formulae on Intestinal Flora Composition -- 5.4.2. Protecting the Intestinal Mucosa Barrier Function and Preventing the Intestinal Bacteria Translocation Penetration -- 5.4.2.1. Single TCM Herbs -- 5.4.2.2. TCM Formulae -- 5.4.2.3. Other TCM Preparations -- References -- Chapter 6: Application of Connectivity Map (CMAP) Database to Research on Traditional Chinese Medicines (TCMs) -- 6.1. Establishing the CMAP Database -- 6.1.1. Molecules Treating Cell Lines -- 6.1.2. The CMAP Concept -- 6.2. Application in TCM -- 6.2.1. Application in Components of TCM -- 6.2.2. Application in TCM Formulae -- 6.3. Perspectives -- References -- Section 2: Case Study on Shexiang Baoxin Pill -- Chapter 7: The Study of the Material Basis of the Shexiang Baoxin Pill -- 7.1. Identification of Nonvolatile Constituents in the TCM-Formula Shexiang Baoxin Pill by LC Coupled With DAD-ESI-MS-MS -- 7.1.1. Experimental -- 7.1.1.1. Materials and Chemicals -- 7.1.1.2. Preparation of Samples -- 7.1.1.3. LC-DAD-MS System -- 7.1.2. Results and Discussion -- 7.1.2.1. LC-DAD Analysis of SBP -- 7.1.2.2. ESI-MS(2) Analysis of Authentic Compounds. , 7.1.2.3. LC-DAD-MS-MS Analysis of SBP -- 7.1.3. Conclusion -- 7.2. The Study on Volatile Components in the Shexiang Baoxin Pill -- 7.2.1. Instrumentation and Materials -- 7.2.1.1. Instrumentation -- 7.2.1.2. Reagents -- 7.2.1.3. Chemicals -- 7.2.2. Method and Results -- 7.2.2.1. Preparation of the Standard Solution -- 7.2.2.2. Preparation of Sample Solution -- 7.2.2.3. Chromatographic Conditions -- 7.2.2.4. Identification of SBP -- 7.2.3. Conclusions -- References -- Chapter 8: Study on the Serum Pharmacochemistry of the Shexiang Baoxin Pill -- 8.1. Analysis of the Nonvolatile Constituents in Rat Plasma After Oral Administration of the Baoxin Pill by HPLC-ESI-MS/MS -- 8.1.1. Experimental -- 8.1.1.1. Chemicals and Reagents -- 8.1.1.2. Instrumentation and Conditions -- 8.1.1.3. Animals, Drug Administration, and Blood Sampling -- 8.1.1.4. Sample Preparation -- 8.1.2. Results and Discussion -- 8.1.2.1. LC-ESI-MS/MS Analysis of Shexiang Baoxin Pill Extracts and Plasma Samples -- 8.1.2.2. Method Validation -- 8.1.2.3. Identification of Prototype Components in Rat Plasma -- 8.1.2.4. Identification of Metabolites in Rat Plasma -- 8.1.3. Conclusion -- 8.2. Analysis of the Volatile Constituents in Rat Plasma After Oral Administration of the Shexiang Baoxin Pill by GC-MS -- 8.2.1. Instrument and Reagent -- 8.2.1.1. Mass Spectrometer -- 8.2.1.2. Reagent -- 8.2.1.3. Animal -- 8.2.1.4. Shexiang Baoxin Pill Analysis and Sample Preparation -- 8.2.1.5. Separate Condition -- 8.2.1.6. Mass Condition -- 8.2.2. Results and Discussion -- 8.2.3. Conclusion -- References -- Chapter 9: The Quality Study of the Shexiang Baoxin Pill -- 9.1. The Quality Study of Bovis Calculus in the SBP -- 9.1.1. Experimental -- 9.1.1.1. Reagents and Materials -- 9.1.1.2. Chromatographic System -- 9.1.1.3. Analytical Conditions -- 9.1.1.4. Sample Preparation -- 9.1.1.5. Calibration Curves. , 9.1.2. Results and Discussion -- 9.1.2.1. Chromatographic Analysis -- 9.1.2.2. Validation -- 9.1.2.3. Sample Analysis -- 9.1.3. Conclusions -- 9.2. The Quality Standard of the SBP -- 9.2.1. The Quality Standard of Nonvolatile Components in the SBP -- 9.2.1.1. Experimental -- Reagents and Materials -- Chromatographic System -- Analytical Conditions -- Sample Preparation -- 9.2.1.2. Results and Discussion -- Chemical Fingerprint of SBP -- Sample Analysis and Quality Evaluation -- 9.2.1.3. Conclusions -- 9.2.2. The Quality Standard of Volatile Components in the SBP -- 9.2.2.1. Experimental -- Instruments -- Reagents and Materials -- GC Analysis -- Sample Preparation -- 9.2.2.2. Results and Discussion -- Chemical Fingerprinting Analysis -- Validation -- 9.2.2.3. Conclusions -- References -- Chapter 10: Pharmacokinetic Study of the Shexiang Baoxin Pill -- 10.1. Pharmacokinetic Study of Five Ginsenosides Following Single and Multiple Oral Administrations of The Shexiang Baoxi ... -- 10.1.1. Experimental -- 10.1.1.1. Chemicals and Reagents -- 10.1.1.2. Animals -- 10.1.1.3. Preparation of the SBP Extract and the Determination of Five Ginsenosides in the Extract -- 10.1.1.4. Preparation of Calibration Standards and Quality Control (QC) Samples -- 10.1.1.5. Instruments and LC-MS/MS Conditions -- 10.1.1.6. Sample Preparation -- 10.1.1.7. Method Validation -- 10.1.1.8. PK Study -- Experimental Design for Animals -- PK Calculation and Statistics -- 10.1.2. Results and Discussion -- 10.1.2.1. Method Development -- 10.1.2.2. Method Validation -- 10.1.2.3. PK Study -- Single Dosing -- Mutiple Dosing -- 10.1.3. Conclusions -- 10.2. Pharmacokinetics and Tissue Distribution of Five Bufadienolides From the SBP in Mice -- 10.2.1. Experimental -- 10.2.1.1. Chemicals and Reagents -- 10.2.1.2. Animals -- 10.2.1.3. Instruments and Conditions -- Liquid Chromatography. , Mass Spectrometric Conditions.

Additional Edition: ISBN 0-12-812744-9

Language: English

UID:

Format: 184 S.

ISBN: 3-631-39000-9

Series Statement: Europäische Hochschulschriften : Reihe 1, Deutsche Sprache und Literatur 1824

Note: Zugl.: Beijing, Fremdsprachenuniv., Diss., 1997

Language: German

Subjects: German Studies

Keywords: 1883-1924 Kafka, Franz ; Rezeption ; Hochschulschrift ; Hochschulschrift

URL: Inhaltsverzeichnis

URL: Inhaltsverzeichnis

Author information: Ren, Weidong.

UID:

Format: 1 Online-Ressource (xv, 264 Seiten).

ISBN: 978-1-83916-603-7 , 978-1-83916-604-4

Series Statement: Theoretical and computational chemistry series no. 24

Note: Abweichend vom PDF, ist 2023 auf der Homepage als Erscheinungsjahr genannt

Additional Edition: Erscheint auch als Druck-Ausgabe, Hardcover ISBN 978-1-83916-162-9

Language: English

DOI: 10.1039/9781839166037

URL: Volltext  (URL des Erstveröffentlichers)

URL: lizenzpflichtig

URL: Inhaltsverzeichnis

UID:

Format: 184 Seiten , 21 cm

ISBN: 3631390009

Series Statement: Europäische Hochschulschriften

Language: German

Keywords: Kafka, Franz ; Rezeption ; China ; Geschichte 1979-1993 ; Hochschulschrift

Author information: Ren, Weidong

UID:

Format: 1, 2, 115 Seiten , 图片, 照片, 地图

Edition: 第1版

Original writing title: 发现黄帝城 : 涿鹿故城及周边遗址考古工作报告(2014-2018)

Original writing publisher: 上海 : 上海古籍出版社

ISBN: 9787573202079

Language: Chinese

URL: Inhaltsverzeichnis

UID:

Format: 16, 2, 2, 5, 290 Seiten , Illustrationen, Porträts, Faksimiles , 28 cm

Edition: Di 1 ban

Original writing edition: 第1版

Original writing title: 古涿州佛教刻石

Original writing person/organisation: 杨卫东

Original writing publisher: 石家庄市 : 河北教育出版社

ISBN: 9787543464872 , 754346487X

Content: 本书辑入古涿州辖境内的历代佛教刻石一百七十八件，包括造像、石塔、石柱、刻经、经幢、墓幢、碑碣及历代建筑中具有鲜明佛教文化的石制建筑构件

Note: 有附录 , Includes bibliographical references (p. 286-287) , SBB-PK Berlin

Language: Chinese

UID:

Format: 2, 221 Seiten ; , 20 cm.

Edition: Di yi ban

Original writing title: 关于"异"的研究 /

ISBN: 7-301-03435-0

Series Statement: Bei jing da xue jiang yan cong shu 9

Note: Includes bibliographical references

Language: Chinese

Subjects: Comparative Studies. Non-European Languages/Literatures

Author information: Kubin, Wolfgang, 1945-,

UID:

Format: 5 S. , Ill.

Note: Ausz. aus "Nachhaltige Stadtentwicklung in Dalian, China"

Language: Undetermined