Format:
1 Online-Ressource (129 Seiten, 13477 KB)
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Content:
The sequencing of the human genome in the early 2000s led to an increased interest in cheap and fast sequencing technologies. This interest culminated in the advent of next generation sequencing (NGS). A number of different NGS platforms have arisen since then all promising to do the same thing, i.e. produce large amounts of genetic information for relatively low costs compared to more traditional methods such as Sanger sequencing. The capabilities of NGS meant that researchers were no longer bound to species for which a lot of previous work had already been done (e.g. model organisms and humans) enabling a shift in research towards more novel and diverse species of interest. This capability has greatly benefitted many fields within the biological sciences, one of which being the field of evolutionary biology. Researchers have begun to move away from the study of laboratory model organisms to wild, natural populations and species which has greatly expanded our knowledge of evolution. NGS boasts a number of benefits over more traditional sequencing approaches. The main benefit comes from the capability to generate information for drastically more loci for a fraction of the cost. This is hugely beneficial to the study of wild animals as, even when large numbers of individuals are unobtainable, the amount of data produced still allows for accurate, reliable population and species level results from a small selection of individuals. [...]
Note:
Dissertation Universität Potsdam 2018
Additional Edition:
Erscheint auch als Druck-Ausgabe Westbury, Michael Unraveling evolution through next generation sequencing Potsdam, 2018
Language:
English
Keywords:
Hochschulschrift
URN:
urn:nbn:de:kobv:517-opus4-409981
URL:
https://nbn-resolving.org/urn:nbn:de:kobv:517-opus4-409981
URL:
https://d-nb.info/1218403586/34
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