Format:
Online-Ressource (X, 408 p. 37 illus., 3 illus. in color)
,
digital
Edition:
Springer eBook Collection. Biomedical and Life Sciences
ISBN:
9783662062142
Series Statement:
Handbook of Experimental Pharmacology 160
Content:
This volume intends to provide a panorama of our current understanding of the role of genetic information in the management of cardiovascular disease. A recurring plea from the contributors is the need for more hypothesis-driven, rigorously conducted and analysed clinical research. Perhaps this compilation of knowledge will provide a springboard for the design of informative clinical studies
Note:
Preface -- The Role of Genotyping in Pharmacological Therapy -- Pharmacogenetics and the Treatment of Cardiovascular Disease.- Genetic Polymorphisms and Cardiovascular Drug Metabolism -- Genes that Modify Susceptibility to Atherosclerosis: Targets for Drug Action -- Lipid Lowering Responses Modified by Genetic Variation -- The Genetic Basis of Essential Hypertension and its Implications for Treatment -- Genetic Predisposition to Cardiac Hypertrophy -- Genetic Determinants of Susceptibility, Prognosis and Treatment in Heart Failure -- The Genetics of Cardiac Channelopathies: Implications for Therapeutics -- Insulin Resistance and Cardiovascular Disease - New Insights From Genetics -- Genetic Disruption of Nitric Oxide Synthases and Cardiovascular Disease - Lessons from a Candidate Gene -- Association of Thrombotic Disease with Genetic Polymorphism of Haemostatic Genes - Relevance to Pharmacogenetics -- Genetic Polymorphisms of Adhesion Molecules -- Genetic Regulation of Metalloproteinase Activity: Pathogenic and Therapeutic Implications -- Current Perspectives on Gene and Cell-based Therapies for Myocardial Protection, Rescue and Repair.
Additional Edition:
ISBN 9783642072918
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783642072918
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783540402046
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783662062159
Language:
English
DOI:
10.1007/978-3-662-06214-2
URL:
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