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  • 1
    UID:
    almahu_9949251211002882
    Format: 1 online resource (XVIII, 718 p. 175 illus., 115 illus. in color.)
    Edition: 1st ed. 2012.
    ISBN: 1-61779-782-0
    Series Statement: Springer Protocols Handbooks,
    Content: The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.  Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system.  Volume 2 examines global cerebral ischemia, focal cerebral ischemia, and neonatal hypoxia-ischemia, as well as intensive sections covering traumatic brain injury and spinal cord injury.  Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used.   Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.
    Note: Bibliographic Level Mode of Issuance: Monograph , Introduction (Parts I-III) -- Morphological Assessments of Global Cerebral Ischemia: Viable Cells -- Morphological Assessments of Global Cerebral Ischemia: Degenerated Cells -- Morphological Assessments of Global Cerebral Ischemia: Electron Microscopy -- Biochemical and Molecular Biological Assessments of Global Cerebral Ischemia: mRNA -- Biochemical and Molecular Biological Assessments of Global Cerebral Ischemia: Protein -- Neurobehavioral Assessments of Global Cerebral Ischemia -- Assessment of Neurogenesis in the Dentate Gyrus after Global or Focal Ischemia -- Infarct Measurement in Focal Cerebral Ischemia: TTC Staining -- Morphological Assessments of Focal Cerebral Ischemia: White Matter Injury -- Blood Flow Reduction: Laser Doppler, 14C-IAP -- Biochemical and Molecular Biological Assessments of Focal Cerebral Ischemia: mRNA and MicroRNA -- Biochemical and Molecular Biological Assessments of Focal Cerebral Ischemia: Protein -- Assessments of Inflammation After Focal Cerebral Ischemia -- Neurobehavioral Assessments of Focal Cerebral Ischemia: Sensorimotor Deficit -- Neurobehavioral Assessments of Focal Cerebral Ischemia: Cognitive Deficit -- Assessment of Neurogenesis in Models of Focal Cerebral Ischemia -- Assessment of Angiogenesis in Models of Focal Cerebral Ischemia -- Morphological Assessments of Neonatal Hypoxia-Ischemia: In Situ Cell Degeneration -- Morphological Assessments of Neonatal Hypoxia-Ischemia: White Matter Injury -- Biochemical and Molecular Biological Assessments of Neonatal Hypoxia-Ischemia: Cell Signaling -- Biochemical and Molecular Biological Assessments of Neonatal Hypoxia-Ischemia: Inflammation -- Neurobehavioral Assessments of Neonatal Hypoxia-Ischemia -- Assessment of Neurogenesis and White Matter Regeneration -- Assessments for Traumatic Brain Injury:  An Introduction -- Morphological Assessments of Traumatic Brain Injury -- Assessment of Cerebral Vascular Dysfunction after Traumatic Brain Injury -- Assessment of Membrane Permeability After Traumatic Brain Injury -- Assessment of Neurogenesis by BrdU Labeling After Traumatic Brain Injury -- Electrophysiological Approaches in Traumatic Brain Injury -- Biochemical and Molecular Biological Assessments of Traumatic Brain Injury -- Assessments of Oxidative Damage and Lipid Peroxidation after Traumatic Brain Injury and Spinal Cord Injury -- Neurobehavioral Assessments of Traumatic Brain Injury -- Vestibular Assessments Following Traumatic Brain Injury -- Introduction on Assessments for Spinal Cord Injury -- Morphological Assessments Following Spinal Cord Injury -- Assessment of Lesion and Tissue Sparing Volumes Following Spinal Cord Injury -- Retrograde Axonal Tract Tracing -- Anterograde Axonal Tract Tracing -- Assessments of Gliogenesis After Spinal Cord Injury -- Assessing Microvessels After Spinal Cord Injury -- Physiological Assessment of Spinal Cord Injury -- Electrophysiological Assessment of Spinal Cord Function on Rodents Using tcMMEP and SSEP -- Operant Conditioning of Spinal Cord Reflexes in Rats -- Cellular and Molecular Biological Assessments of Inflammation and Autoimmunity After Spinal Cord Injury -- Neurobehavioral Assessments of Spinal Cord Injury -- Basso, Beattie, and Bresnahan (BBB) Scale Locomotor Assessment Following Spinal Cord Injury and Its Utility as a Criterion for Other Assessments -- High Speed Video Recording Used for the Analysis of Hand Shaping in Over Ground Walking, Cylinder Exploration, Skilled Reaching, and Rung Walking in Rats -- Automated Gait Analysis Following Spinal Cord Injury -- Forelimb Functional Assessments of Rats and Mice After Cervical Spinal Cord Injury -- Swimming as an Assessment of Hindlimb Function in Animals with Traumatic Spinal Cord Injury -- Neuroimaging Assessment of Spinal Cord Injury in Rodents. , English
    Additional Edition: ISBN 1-61779-781-2
    Language: English
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Singapore, | Beijing :Higher Edication Press,
    UID:
    almahu_BV045275022
    Format: 1 Online-Ressource (xvii, 267 Seiten) : , Illustrationen.
    ISBN: 978-981-130-875-8
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-130-874-1
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-130-876-5
    Language: English
    Keywords: Bildungspolitik
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 3
    Online Resource
    Online Resource
    Beijing, [China] ; : Science Press :
    UID:
    almahu_9948026300802882
    Format: 1 online resource (432 pages) : , illustrations (some color)
    ISBN: 0-12-801732-5
    Uniform Title: Neural regeneration (So)
    Content: Annotation
    Note: Bibliographic Level Mode of Issuance: Monograph , English
    Additional Edition: ISBN 0-12-801834-8
    Language: English
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  • 4
    Online Resource
    Online Resource
    Singapore :Springer,
    UID:
    almahu_BV047463372
    Format: 1 Online-Ressource (xxi, 389 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-981-1637-24-7
    Series Statement: Education in the Asia-Pacific region volume 60
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1637-23-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1637-25-4
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1637-26-1
    Language: English
    Keywords: Entrepreneurship ; Berufsausbildung
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 5
    UID:
    almahu_9949251693102882
    Format: 1 online resource (XVIII, 724 p. 167 illus., 125 illus. in color.)
    Edition: 1st ed. 2012.
    ISBN: 1-61779-576-3
    Series Statement: Springer Protocols Handbooks,
    Content: The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.  Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system.  Volume 1 examines general assessments in morphology, physiology, biochemistry and molecular biology, neurobehavior, and neuroimaging, as well as extensive sections on subarachnoid hemorrhage, cerebral vasospasm, and intracerebral hemorrhage.  Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used.   Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.
    Note: Bibliographic Level Mode of Issuance: Monograph , Histopathological Assessments of Animal Models of Cerebral Ischemia -- Assessment of Cell Death: Apoptosis, Necrosis, or In Between -- The Stereology and 3D Volume Analyses in Nervous Tissue -- Assessments of Reactive Astrogliosis Following CNS Injuries -- Physiological Assessment in Stroke Research -- EEG, Evoked Potential (EP), and Extracellular Single Unit Recordings In Vivo -- Intracellular Recording In Vivo and Patch-Clamp Recording on Brain Slices -- Electrophysiological Evaluation of Synaptic Plasticity in Injured CNS -- Characterization of RNA -- MicroRNA Expression Profiling of Rat Blood and Brain Tissues: TaqMan Real-Time PCR MicroRNA Assays -- Protein Analysis -- Application of Zymographic Methods to Study Matrix Enzymes Following Traumatic Brain Injury -- Rodent Behavioral Assessment in the Home Cage Using the SmartCageTM System -- Assessments of Cognitive Function Following Traumatic Brain Injury -- Assessment of Cognitive and Sensorimotor Deficits -- Emotional and Anxiety Assessments in CNS Disorders -- Neuroimaging Assessment of Traumatic Brain Injury -- Imaging of Myelin by Coherent Anti-Stokes Raman Scattering Microscopy -- Grading Scales for Subarachnoid Hemorrhage -- Acute Physiologic and Morphologic Assessment Following Subarachnoid Hemorrhage -- Aneurysmal Subarachnoid Hemorrhage Grading in Animal Models -- Physiological Assessments of Subarachnoid Hemorrhage -- Spreading Depolarization -- Assessment of Neurovascular Coupling -- Assessment of Global Ischemia -- Assessment of Microthromboembolism after Subarachnoid Hemorrhage -- Intracranial Pressure Assessments -- Assessment of Blood-Brain Barrier Breakdown -- Electrophysiology and Morris Water Maze to Assess Hippocampal Function after Experimental Subarachnoid Hemorrhage -- Biochemical and Molecular Biological Assessments of Subarachnoid Hemorrhage -- Neurobehavioral Assessments of Subarachnoid Hemorrhage -- Neuroimaging Assessment of Subarachnoid Hemorrhage -- Introduction to Problems of Post-Subarachnoid Hemorrhage Delayed Cerebral Vasospasm -- Morphological Assessments of Cerebral Vasospasm -- Vasospasm: Measurement of Diameter, Perimeter and Wall Thickness -- Light Microscopic Assessment -- Electron Microscopic Assessment -- Morphological Assessment of Microcirculation -- Electrophysiological Assessment of Cerebral Vasospasm -- Cranial Window Assessments in Experimental aSAH in Mice -- Laser Speckle Contrast Analysis (LASCA) Imaging -- Ion Channel Assessment -- Biochemical Assessments of Cerebral Vasospasm: Measurement of cGMP, PKC, and PTK in Cerebral Arteries -- Assessment of Intracellular Calcium in Cerebral Artery Myocytes -- Neurobehavioral Assessments of Cerebral Vasospasm -- Neuroimaging Assessment of Cerebral Vasospasm -- Morphological Assessment of Intracerebral Hemorrhage -- Immunological Response to Experimental Intracerebral Hemorrhage: Morphological Assessments -- Intracranial Pressure Assessment -- Hemoglobin Measurements -- Biochemical and Molecular Biological Assessments of Intracerebral Hemorrhage -- Neurobehavioral Assessments of Intracerebral Hemorrhage -- Corner Turning Test for Evaluation of Asymmetry after Intracerebral Hemorrhage in Rodents -- Forelimb Use Asymmetry Analysis of Vertical Exploratory Activity after Intracerebral Hemorrhage in Rats and Mice -- The Vibrissae-Elicited Forelimb Placing Test after Intracerebral Hemorrhage in Rodents -- Imaging of Hematoma and Perihematomal Edema in Experimental Intracerebral Hemorrhage. , English
    Additional Edition: ISBN 1-61779-575-5
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore, Singapore :Springer,
    UID:
    edoccha_BV049397440
    Format: 1 Online-Ressource (xix, 252 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-981-99-1835-5
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-99-1834-8
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-99-1836-2
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-99-1837-9
    Language: English
    Keywords: Wirtschaftspädagogik ; Entrepreneurship ; Internationaler Vergleich ; Aufsatzsammlung
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 7
    Online Resource
    Online Resource
    Singapore, Singapore :Springer,
    UID:
    almafu_BV049397440
    Format: 1 Online-Ressource (xix, 252 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-981-99-1835-5
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-99-1834-8
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-99-1836-2
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-99-1837-9
    Language: English
    Keywords: Wirtschaftspädagogik ; Entrepreneurship ; Internationaler Vergleich ; Aufsatzsammlung
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 8
    UID:
    almafu_9959151477402883
    Format: 1 online resource (x, 544 pages).
    Edition: 2nd ed. 2019.
    ISBN: 3-030-16082-3
    Series Statement: Springer Series in Translational Stroke Research,
    Content: Despite numerous recent studies and exciting discoveries in the field, only limited treatments are available today for the victims of acute brain and spinal cord injuries. Animal Models of Acute Neurological Injuries, Second Edition, provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that often inhibit advances in this specialized research field. In the 10 years since publication of the first edition of this book, some animal models have become obsolete, some have stood the test of time, and newer models have emerged to enhance our knowledge of acute neurological injuries. The second edition continues to offer the research community tested approaches for this area of investigation. As with the first edition, top experts have developed and contributed these animal models. The book’s focus remains hands-on, practical applications of the models, rather than a theoretical approach. Each chapter contains a proven procedure enhanced by clear figures, illustrations, or videos. This new edition presents its readily reproducible protocols with clarity and consistency to best aid neuroscientists and neurobiologists. As with the first edition, the second edition is comprehensive and cutting-edge. Animal Models of Acute Neurological Injuries, Second Edition, is an ideal guide for research professionals, at all stages of their careers, who wish to pursue this vital course of study with the proficiency and precision required by the field.
    Note: Preface -- Animal Protocol -- Anesthesia and Analgesia for Research Animals -- Rodent Surgical Procedures and Tissue Collection -- Brain Monitoring -- Veterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies: An Update -- Four Vessel-Occlusion Model in Rats -- Rat Model of Global Cerebral Ischemia: Two Vessel-Occlusion (2VO) Model of Forebrain Ischemia -- Rodent Model of Pediatric Asphyxial Cardiac Arrest -- Transient Middle Cerebral Artery Occlusion Model in Rodents -- Targeted Occlusion to Surface and Deep Vessels in Neocortex Via Linear and Nonlinear Optical Absorption -- Intraluminal Middle Cerebral Artery Occlusion Model in Mice -- Inducing Hemorrhagic Transformation following Middle Cerebral Artery Occlusion via Acute Hyperglycemia in Rats -- Cerebral Palsy Model of Uterine Ischemia -- Model of Neonatal Focal Cerebral Ischemia-Reperfusion -- Monofilament Perforation Subarachnoid Hemorrhage Rat Model -- Filament Perforation Subarachnoid Hemorrhage Mouse Model -- Non-Human Primate Model of Cerebral Vasospasm -- Blood Injection Intracerebral Hemorrhage Rat Model -- Collagenase Model of Intracerebral Hemorrhage in Rats -- A Rat Model of Cerebellar Hemorrhage using Bacterial Collagenase Injection -- Blood Injection Intracerebral Hemorrhage Mouse Model -- Blood Injection Intracerebral Hemorrhage Pig Model -- Collagenase Induced Pontine Hemorrhage in Rats -- Germinal Matrix Hemorrhage Neonatal Rat Model Using Bacterial Collagenase Injection -- Fluid Percussion Injury Model -- Controlled Cortical Impact Model of Experimental Brain Trauma -- Mild Blast-induced Traumatic Brain Injury Model -- Rat Model of Surgical Brain Injury -- MASCIS Spinal Cord Contusion Model -- ESCID Spinal Cord Contusion Model -- Cervical Hemicontusion Spinal Cord Injury Model -- Applications of the Infinite Horizon Spinal Cord Contusion Injury Model -- Clip Impact-Compression Model -- Method of Spinal Cord Contusion Injury Created by Tissue Displacement -- Experimental Laceration Spinal Cord Injury Model in Rodents -- Rodent Spinal Cord Demyelination Models -- Spinal Cord Lateral Hemisection and Implantation of Guidance Channels -- Spinal Root Avulsion and Repair -- Index.
    Additional Edition: ISBN 3-030-16080-7
    Language: English
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  • 9
    UID:
    almafu_9959326947502883
    Format: 1 online resource (xii, 308 pages, 16 unnumbered pages of plates) : , illustrations (some color)
    ISBN: 9780470119501 , 0470119500 , 9780470119495 , 0470119497
    Series Statement: Chemical analysis ;
    Content: An overview of current research and developments in ultrasensitive bioanalysis. New platforms of ultrasensitive analysis of biomolecules and single living cells using multiplexing, single nanoparticle sensing, nano-fluidics, and single-molecule detection are advancing every scientific discipline at an unprecedented pace.
    Note: Is one enough? / Andrew C. Beveridge, James H. Jett, and Richard A. Keller -- Dissecting cellular activity from single genes to single mRNAs / Xavier Darzacq, Robert H. Singer, and Yaron Shav-Tal -- Probing membrane transport of single live cells using single-molecule detection and single nanoparticle assay / Xiao-Hong Nancy Xu, Yujun Song, and Prakash Nallathamby -- Nanoparticle probes for ultrasensitive biological detection and imaging / Amit Agrawal, Tushar Sathe, and Shuming Nie -- Tailoring nanoparticles for the recognition of biomacromolecule surfaces / Mrinmoy De [and others] -- Nanoscale chemical analysis of individual subcellular compartments / Gina S. Fiorini and Daniel T. Chiu -- Ultra sensitive time-resolved near-IR fluorescence for multiplexed bioanalysis / Li Zhu and Steven A. Soper -- Ultrasensitive microarray detection of DNA using enzymatically amplified SPR imaging / Hye Jin Lee, Alastair W. Wark, and Robert M. Corn -- Ultrasensitive analysis of metal ions and small molecules in living cells / Richard B. Thompson -- Electrochemistry inside and outside single nerve cells / Daniel J. Eves and Andrew G. Ewing -- Electrochemiluminescence detection in bioanalysis / Xiao-Hong Nancy Xu and Yanbing Zu -- Single-cell measurements with mass spectrometry / Eric B. Monroe [and others] -- Outlooks of ultrasensitive detection in bioanalysis / Xiao-Hong Nancy Xu.
    Additional Edition: Print version: New frontiers in ultrasensitive bioanalysis. Hoboken, N.J. : Wiley-Interscience, ©2007 ISBN 9780471746607
    Additional Edition: ISBN 0471746606
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books.
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  • 10
    UID:
    gbv_277857635
    Format: 124 S , Ill., graph. Darst
    Note: Zürich, Univ., Diss
    Language: Undetermined
    Keywords: Hochschulschrift
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