Kooperativer Bibliotheksverbund

UID:

Format: 1 Online-Ressource (XXI, 364 Seiten) : , Illustrationen.

Edition: 1st ed. 2020

ISBN: 978-981-150-156-2

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-150-155-5

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-150-157-9

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-150-158-6

Language: English

DOI: 10.1007/978-981-15-0156-2

URL: Volltext  (URL des Erstveröffentlichers)

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031816088&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

URL: lizenzpflichtig

URL: Cover

URL: Volltext  (URL des Erstveröffentlichers)

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031816088&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

UID:

Format: 1 online resource (242 pages)

ISBN: 0-323-99378-8

Content: Principles of Genomics and Proteomics is the perfect reference for graduate students and researchers in these areas to understand its principles and execute precise and reproducible experiments. Following an introductory chapter, the book dives into proper research, including genome mapping. Experiments covered in the book span from Sangers Sequencing, Shotgun sequencing, SAGE analysis, DNA footprinting, Gel retardation, ChIP, and protein resolution methods, including PAGE, 2D gel electrophoresis and isoelectric focusing. Biophysical techniques are also described in detail, including ultraviolet and visible light spectroscopy, fluorescence spectroscopy, NMR and X-ray diffraction. A final proteome analysis is dedicated to functional analysis. Other chapters cover applications of omics technologies broadly. This book is the perfect reference for genetics labs around the world. Graduate students will benefit from the structured and detailed coverage of methods and established researchers will benefit from the book for staff training in research and may find it particularly helpful in enhancing reproducibility of experiments. --

Note: Understanding the OMICS techniques: an introduction to genomics and proteomics -- Genome mapping -- Analysis of genomes-I -- Analysis of genomes-II -- Nutrigenomics: Insights into the influence of nutrients on functional dynamics of genomes -- Analysis of proteomes-I -- Analysis of proteomes-II -- Analysis of proteomes-III -- Analysis of proteomes-IV -- Beyond genomics and proteomics

Additional Edition: Print version: Ahmad Mir, Rakeeb Principles of Genomics and Proteomics San Diego : Elsevier,c2023 ISBN 9780323990455

Language: English

UID:

Format: 1 Online-Ressource (XIV, 266 Seiten) : , Illustrationen.

ISBN: 978-981-1638-76-3

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-75-6

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-77-0

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-78-7

Language: English

DOI: 10.1007/978-981-16-3876-3

URL: Volltext  (URL des Erstveröffentlichers)

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XVIII, 350 p. 32 illus., 30 illus. in color)

ISBN: 9789811074790

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-10-7478-3

Language: English

Subjects: Biology

Keywords: Pflanzenzelle ; Abiotischer Faktor ; Stressor ; Signaltransduktion ; Aufsatzsammlung

DOI: 10.1007/978-981-10-7479-0

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XIV, 266 Seiten) , Illustrationen

ISBN: 9789811638763

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-75-6

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-77-0

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-78-7

Language: English

DOI: 10.1007/978-981-16-3876-3

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XXI, 364 Seiten) , Illustrationen

Edition: 1st ed. 2020

ISBN: 9789811501562

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-150-155-5

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-150-157-9

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-150-158-6

Language: English

DOI: 10.1007/978-981-15-0156-2

URL: Volltext  (URL des Erstveröffentlichers)

URL: Buchcover

UID:

Format: 1 online resource (258 pages)

Edition: 1st ed.

ISBN: 9780443219245

Note: Front Cover -- Concepts and Techniques in OMICS and System Biology -- Concepts and Techniques in OMICS and System Biology -- Copyright -- Dedication -- Contents -- About the authors -- Preface -- Acknowledgments -- 1 - Introduction to proteomics, metabolomics, and ionomics -- Introduction -- Proteomics techniques-Low throughput and high throughput techniques -- Low-throughput techniques -- High-throughput techniques -- Introduction to metabolomics -- Introduction to ionomics -- Applications of proteomics -- Agriculture -- Food science -- Medicine -- Systems biology -- Paleo-proteomics -- Applications of metabolomics -- Metabolomics in plant development -- Metabolomics during plant stress -- Application of metabolomics for genetically modified (GM) crops -- Metabolomics and crop improvement -- Applications of ionomics -- Ionomics in normal plant growth -- Ionomics and plant biotic stress -- Ionomics and abiotic stress in crops -- Quantitative trait loci (QTLs) regulating ionomics -- Conclusion -- References -- 2 - Proteomics and the techniques applicable -- Introduction -- Protein primary structure -- Protein secondary structure -- Hydrogen bond -- Psi and phi angles -- Unusual secondary structures -- Motifs -- Tertiary protein structure -- Protein domains -- Quaternary protein structure -- Protein structure determination by X-ray crystallography -- Requirements -- X-ray generation -- X-ray diffraction -- X-ray detector -- NMR -- Protein structure determination using NMR -- Principles and applications of mass spectrometry -- Principles of Mass spectrometry -- Applications of Mass spectrometry (Pukala & -- Robinson, 2022) -- Proteomics: Basic understanding -- Gel-Based proteomics -- Gel-free proteomics -- iTRAQ -- Conclusion -- References -- Further reading -- 3 - Advances in proteomics techniques -- Introduction -- MASCOT -- pQuant software. , Trans Proteomic Pipeline (TPP) software -- Census software -- MaxQuant software -- Advanced features -- Exploring proteome databases -- UniProt -- NCBI protein -- Ensembl -- Protein Data Bank -- PeptideAtlas -- Human protein Atlas -- PRIDE database -- Human proteome organization proteomics standards initiative repositories -- RefSeq -- SWISS-MODEL repository -- Conclusion -- References -- Further reading -- 4 - Aspects of protein interactions -- Coimmuno precipitation -- Antibody selection -- Cell lysis -- Preclearing -- Immunoprecipitation -- Washing -- Elution -- Analysis -- Applications -- Pull-down assays -- Analysis -- Cross-linking, label transfer and far-Western blot analysis -- Conclusion -- References -- 5 - Metabolomics and the techniques applicable -- Introduction -- Objective -- Methods of analysis -- Biological applications -- Challenges -- Use of 1D NMR in metabolomic analysis -- Quantitative analysis -- Structural elucidation -- Dynamic studies -- Metabolic profiling -- Biomarker discovery -- Stable isotope tracing -- Quality control in bioprocessing -- Environmental metabolomics -- Pharmacometabolomics -- Food and nutrition studies -- In vivo metabolic imaging -- Use of 2D NMR in metabolomic analysis -- Multivariate analysis -- Data Preprocessing -- Multivariate analysis techniques -- Variable selection -- Validation -- Biomarker identification -- Biological Validation -- Interpretation and reporting -- Identification of metabolites as biomarkers -- Biomarker selection -- Biomarker validation -- Biological Interpretation -- Clinical validation -- Conclusion -- References -- 6 - Advances in metabolomic techniques -- Basics of softwares used in metabolomics -- Preprocessing software -- Data analysis and visualization -- Statistical analysis -- Metabolite identification -- Quantification and pathway analysis -- NMR data analysis. , Machine learning tools -- Database search tools -- Database management -- Open source and commercial solutions -- XCMS and metaXCMS -- metaXCMS: Finding shared alterations among many sample classes -- Data processing workflow using metaXCMS -- MetAlign and LIMSA -- MetAlign -- LIMSA -- Discovers and integrates peaks -- Identifies peaks -- Corrects peak areas for overlap -- Quantifies identified species -- Instrument-independent processing -- Text-format MS spectra processing -- Conclusion -- References -- Further reading -- 7 - Ionomics and the techniques applicable -- Introduction -- Definition of ionomics -- Importance of ionomics in plant science -- Techniques for ionomics -- Applications of ionomics -- Ionome analysis for plant stress responses -- Ionome analysis for plant nutrition and soil-plant interactions -- Ionome analysis for breeding and crop improvement -- Limitations and challenges of ionomics -- Conclusion -- References -- 8 - An introduction to systems biology -- Introduction -- Definition of systems biology -- Historical overview of systems biology -- Importance of systems biology in modern biology -- Objectives of systems biology -- Tools, techniques, and approaches used in systems biology -- Experimental approach (high-throughput data generation techniques) -- Bioinformatics and computational approaches -- Network analysis -- Applications of systems biology -- Drug development and personalized medicine -- Understanding complex diseases -- Environmental and agricultural applications -- Synthetic biology and biotechnology -- Challenges and limitations of systems biology -- Future of systems biology -- Conclusion -- References -- 9 - System biological aspects related to binding and modeling pathways -- Introduction -- Enzyme kinetics -- Michaelis-menten kinetics -- Biological oscillators -- Principle of biological oscillators. , Genetic oscillators -- Cell-cell communication in bacteria -- Quorum sensing -- Steps involved in quorum sensing -- Quorum sensing in gram-positive bacteria -- Quorum sensing in gram-negative bacteria -- Application of quorum sensing -- Limitations of quorum sensing -- Systems approach to model pathways and networks -- Gene regulation at a single-cell level: An intricate dance of molecular control -- Network building analysis for biological processes -- Negative and positive autoregulation -- References -- Further reading -- 10 - Application of omics and systems biology in agriculture and other allied fields -- Metabolomics -- Interactomics -- Types of biomolecular interactions -- Techniques and approaches in interactomics -- Significance and applications -- Challenges and limitations in studying interactomics -- Ionomics -- Analytical techniques required to study ionomics -- Systems biology -- Challenges and limitations of systems biology -- References -- Index -- Back Cover.

Additional Edition: ISBN 9780443219238

Language: English

UID:

Format: 1 online resource (242 pages)

ISBN: 0-323-99378-8

Content: Principles of Genomics and Proteomics is the perfect reference for graduate students and researchers in these areas to understand its principles and execute precise and reproducible experiments. Following an introductory chapter, the book dives into proper research, including genome mapping. Experiments covered in the book span from Sangers Sequencing, Shotgun sequencing, SAGE analysis, DNA footprinting, Gel retardation, ChIP, and protein resolution methods, including PAGE, 2D gel electrophoresis and isoelectric focusing. Biophysical techniques are also described in detail, including ultraviolet and visible light spectroscopy, fluorescence spectroscopy, NMR and X-ray diffraction. A final proteome analysis is dedicated to functional analysis. Other chapters cover applications of omics technologies broadly. This book is the perfect reference for genetics labs around the world. Graduate students will benefit from the structured and detailed coverage of methods and established researchers will benefit from the book for staff training in research and may find it particularly helpful in enhancing reproducibility of experiments. --

Note: Understanding the OMICS techniques: an introduction to genomics and proteomics -- Genome mapping -- Analysis of genomes-I -- Analysis of genomes-II -- Nutrigenomics: Insights into the influence of nutrients on functional dynamics of genomes -- Analysis of proteomes-I -- Analysis of proteomes-II -- Analysis of proteomes-III -- Analysis of proteomes-IV -- Beyond genomics and proteomics

Additional Edition: Print version: Ahmad Mir, Rakeeb Principles of Genomics and Proteomics San Diego : Elsevier,c2023 ISBN 9780323990455

Language: English

UID:

Format: 1 online resource (242 pages)

ISBN: 0-323-99378-8

Content: Principles of Genomics and Proteomics is the perfect reference for graduate students and researchers in these areas to understand its principles and execute precise and reproducible experiments. Following an introductory chapter, the book dives into proper research, including genome mapping. Experiments covered in the book span from Sangers Sequencing, Shotgun sequencing, SAGE analysis, DNA footprinting, Gel retardation, ChIP, and protein resolution methods, including PAGE, 2D gel electrophoresis and isoelectric focusing. Biophysical techniques are also described in detail, including ultraviolet and visible light spectroscopy, fluorescence spectroscopy, NMR and X-ray diffraction. A final proteome analysis is dedicated to functional analysis. Other chapters cover applications of omics technologies broadly. This book is the perfect reference for genetics labs around the world. Graduate students will benefit from the structured and detailed coverage of methods and established researchers will benefit from the book for staff training in research and may find it particularly helpful in enhancing reproducibility of experiments. --

Note: Understanding the OMICS techniques: an introduction to genomics and proteomics -- Genome mapping -- Analysis of genomes-I -- Analysis of genomes-II -- Nutrigenomics: Insights into the influence of nutrients on functional dynamics of genomes -- Analysis of proteomes-I -- Analysis of proteomes-II -- Analysis of proteomes-III -- Analysis of proteomes-IV -- Beyond genomics and proteomics

Additional Edition: Print version: Ahmad Mir, Rakeeb Principles of Genomics and Proteomics San Diego : Elsevier,c2023 ISBN 9780323990455

Language: English

UID:

Format: 1 Online-Ressource (XIV, 266 Seiten) : , Illustrationen.

ISBN: 978-981-1638-76-3

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-75-6

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-77-0

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1638-78-7

Language: English

DOI: 10.1007/978-981-16-3876-3

URL: Volltext  (URL des Erstveröffentlichers)