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Berlin Brandenburg

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  • 1
    In: Critical Care Medicine, 2011, Vol.39(6), pp.1597-1598
    Keywords: Erythrocyte Transfusion ; Shock, Hemorrhagic -- Therapy ; Wounds and Injuries -- Complications;
    ISSN: 0090-3493
    E-ISSN: 15300293
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  • 2
    Language: English
    In: The Lancet, 22 September 2012, Vol.380(9847), pp.1099-1108
    Description: Most surgeons have adopted damage control surgery for severely injured patients, in which the initial operation is abbreviated after control of bleeding and contamination to allow ongoing resuscitation in the intensive-care unit. Developments in early resuscitation that emphasise rapid control of bleeding, restrictive volume replacement, and prevention or early management of coagulopathy are making definitive surgery during the first operation possible for many patients. Improved topical haemostatic agents and interventional radiology are becoming increasingly useful adjuncts to surgical control of bleeding. Better understanding of trauma-induced coagulopathy is paving the way for the replacement of blind, unguided protocols for blood component therapy with systemic treatments targeting specific deficiencies in coagulation. Similarly, treatments targeting dysregulated inflammatory responses to severe injury are under investigation. As point-of-care diagnostics become more suited to emergency environments, timely targeted intervention for haemorrhage control will result in better patient outcomes and reduced demand for blood products. Our Series paper describes how our understanding of the roles of the microcirculation, inflammation, and coagulation has shaped new and emerging treatment strategies.
    Keywords: Medicine
    ISSN: 0140-6736
    E-ISSN: 1474-547X
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  • 3
    Language: English
    In: The Lancet, 18 October 2014, Vol.384(9952), pp.1466-1475
    Description: Postinjury abdominal compartment syndrome (ACS) is an example of a deadly clinical occurrence that was eliminated by strategic research and focused preventions. In the 1990s, the syndrome emerged with the widespread use of damage control surgery and aggressive crystalloid-based resuscitation. Patients who previously exsanguinated on the operating made it to intensive care units, but then developed highly lethal hyperacute respiratory, renal, and cardiac failure due to increased abdominal pressure. Among many factors, delayed haemorrhage control and preload driven excessive use of crystalloid resuscitation were identified as modifiable predictors. The surrogate effect of preventive strategies, including the challenge of the 40-year-old standard of large volume crystalloid resuscitation for traumatic shock, greatly reduced cases of ACS. The discoveries were rapidly translated to civilian and military trauma surgical practices and fundamentally changed the way trauma patients are resuscitated today with substantially improved outcomes.
    Keywords: Medicine
    ISSN: 0140-6736
    E-ISSN: 1474-547X
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  • 4
    Language: English
    In: The Medical Journal of Australia, May 2, 2016, Vol.204(8), p.302(1)
    Description: WorkSafe initiative deals with occupational serious injuries caused due to fall from ladders. Non occupational ladder falls become difficult to control due to varied behavioural factors that contributes to the injury.
    Keywords: Occupational Safety And Health -- Management ; Injuries -- Care And Treatment ; Injuries -- Prevention
    ISSN: 0025-729X
    Source: Cengage Learning, Inc.
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  • 5
    In: The Journal of Trauma and Acute Care Surgery, 2012, Vol.72(5), pp.1452-1453
    ISSN: 0022-5282
    E-ISSN: 21630763
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  • 6
    In: Critical Care Medicine, 2010, Vol.38(9 Suppl, Current Management of the Critically Ill Surgical Patient), pp.S445-S451
    Description: Compartment syndrome is defined as the dysfunction of organs/tissues within the compartment due to limited blood supply caused by increased pressure within the compartment. The aim of this article is to introduce and discuss acute compartment syndromes that are essential for critical care physicians to recognize and manage. Various pathophysiological mechanisms (ischemia-reperfusion syndrome, direct trauma, localized bleeding) could lead to increased compartmental pressure and decreased blood flow through the intracompartmental capillaries. Although compartment syndromes are described in virtually all body regions, the etiology, diagnosis, treatment, and prevention are best characterized for three key body regions (extremity, abdominal, and thoracic compartment syndromes). Compartment syndromes can be classified as either primary (pathology/injury is within the compartment) or secondary (no primary pathology or injury within the compartment), and based on the etiology (e.g., trauma, burn, sepsis). A recently described phenomenon is the “multiple” compartment syndrome or “poly”-compartment syndrome, which is usually a complication of a severe shock and massive resuscitation. The prevention of compartment syndromes is based on preemptive open management of compartments (primary syndromes) in high-risk patients and/or careful fluid resuscitation (both primary and secondary syndromes) to limit interstitial swelling.
    Keywords: Compartment Syndromes;
    ISSN: 0090-3493
    E-ISSN: 15300293
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  • 7
    Language: English
    In: ANZ Journal of Surgery, July-August, 2014, Vol.84(7-8), p.499(2)
    Description: To purchase or authenticate to the full-text of this article, please visit this link: http://onlinelibrary.wiley.com/doi/10.1111/ans.12572/abstract Byline: Zsolt J. Balogh ***** No abstract is available for this article. *****
    ISSN: 1445-1433
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  • 8
    Language: English
    In: Journal of Paediatrics and Child Health, July, 2013, Vol.49(7), p.557(7)
    Description: Byline: Rebecca J Mitchell, Kate Curtis, Andrew JA Holland, Zsolt J Balogh, Julie Evans, Kellie L Wilson Keywords: cost; health economics; health service; injury; paediatric; trauma Aims To describe the costs of acute trauma admissions for children aged [less than or equal to]15 years in trauma centres; to identify predictors of higher treatment costs and quantify differences in actual and state-wide average cost in New South Wales (NSW), Australia. Method Admitted trauma patient data provided by 12 trauma centres was linked with financial data for 2008-2009. Demographic, injury details and injury severity scores (ISS) were obtained from trauma registries. Individual patient costs, Australian Refined Diagnostic Related Groups (AR-DRG) and state-wide average costs were obtained. Actual costs incurred by each hospital were compared with state-wide AR-DRG average costs. Multivariate multiple linear regression identified predictors of cost. Results There were 3493 patients with a total cost of AUD$20.2 million. Falls (AUD$6.7 million) and road trauma (AUD$4.4 million) had the highest total expenditure. The reduction in cost between ISS 12 was significant (P 〈 0.0001). The median cost of injury increased with every additional body region injured (P 〈 0.0001). For each additional day spent in hospital, there was an increased cost of AUD$1898 and patients admitted to an intensive care unit (ICU) cost AUD$7358 more than patients not admitted to ICU. The total costs incurred by trauma centres were AUD$1.4 million above the NSW peer group average cost estimates. Conclusions The high financial cost of paediatric patient treatment highlights the need to ensure prevention remains a priority in Australia. Hospitals tasked with providing trauma care should be appropriately funded and future funding models should consider trauma severity. Author Affiliation: Article Note: Conflict of interest: None declared.
    Keywords: Pediatrics -- Analysis ; Health Care Costs -- Analysis
    ISSN: 1034-4810
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  • 9
    In: ANZ Journal of Surgery, July 2014, Vol.84(7-8), pp.499-500
    Description: To purchase or authenticate to the full-text of this article, please visit this link: http://onlinelibrary.wiley.com/doi/10.1111/ans.12573/abstract Byline: Zsolt J. Balogh ***** No abstract is available for this article. *****
    Keywords: Quality of Health Care ; Trauma Centers;
    ISSN: 1445-1433
    E-ISSN: 1445-2197
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  • 10
    In: ANZ Journal of Surgery, June 2014, Vol.84(6), pp.399-400
    Keywords: Periodicals As Topic ; Publishing ; Wounds and Injuries;
    ISSN: 1445-1433
    E-ISSN: 1445-2197
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