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  • 1
    UID:
    b3kat_BV040237006
    Format: 1 Online-Ressource (XIV, 310 Seiten) , Diagramme
    ISBN: 9783805595674
    Series Statement: Progress in respiratory research Vol. 39
    Content: Asthma, allergy and chronic obstructive lung disease are common throughout the world and are increasing in incidence, particularly in the developing world. This volume provides a state-of-the-art account of the identification of new targets and the development of new therapies for these conditions. Some 40 chapters by clinical academics and senior members of the pharmaceutical industry detail the latest breakthroughs in research and development. In asthma, a promising approach is the use of therapy directed against specific Th2 responses through biological antagonists of IL-5, IL-4 and IL-13. There have also been major advances in our understanding of innate immune responses to pathogen-associated molecular patterns, and in the area of Toll-like receptors.〈br〉Up to date and comprehensive, this book will be of particular relevance to those working in the pharmaceutical industry (in preclinical research and clinical development), to academic researchers in the field of respiratory medicine, and to respiratory health care specialists
    Note: Reporting the latest progress
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-9566-7
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Bronchialasthma ; Obstruktive Ventilationsstörung ; Targeted drug delivery ; Arzneimittelentwicklung ; Aufsatzsammlung ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    URL: Volltext  (lizenzpflichtig)
    Author information: Barnes, Peter J. 1946-
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  • 2
    UID:
    b3kat_BV017448437
    Format: X, 376 S. , Ill., graph. Darst.
    ISBN: 3540004645
    Series Statement: Handbook of experimental pharmacology 161
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Bronchialasthma ; Pharmakotherapie ; Obstruktive Ventilationsstörung ; Pharmakotherapie ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
    Author information: Barnes, Peter J. 1946-
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  • 3
    Book
    Book
    New York u.a. : Acad. Pr.
    UID:
    b3kat_BV000297867
    Format: XI, 425 S. , Ill.
    ISBN: 0120790203
    Series Statement: Food science and technology
    Language: German
    Keywords: Lipide ; Getreideprodukt
    Author information: Barnes, Peter J. 1946-
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  • 4
    UID:
    b3kat_BV026090801
    Format: VI, 282 S. , Ill., graph. Darst., Kt.
    ISBN: 0333536053 , 0333515900
    Language: Undetermined
    Keywords: Tropen ; Kinderkrankheit ; Subtropen ; Kinderkrankheit
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  • 5
    UID:
    b3kat_BV005416650
    Format: XV, 203 S. , Ill., graph. Darst.
    ISBN: 3110136015
    Series Statement: Pneumologisches Kolloquium 7
    Note: Literaturangaben
    Language: German
    Subjects: Medicine
    RVK:
    Keywords: Bronchialasthma ; Konferenzschrift ; Kongress ; Konferenzschrift
    Author information: Dorow, Peter
    Author information: Barnes, Peter J. 1946-
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  • 6
    Book
    Book
    Oxford [u.a.] : Butterworth-Heinemann
    UID:
    b3kat_BV008331381
    Format: XIII, 282 S. , Ill., graph. Darst.
    Edition: 1. publ.
    ISBN: 0750607122
    Series Statement: Diseases of the heart and lung
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Atmungsorgan ; Krankheit
    Author information: Barnes, Peter J. 1946-
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  • 7
    Book
    Book
    Oxford [u.a.] : Blackwell Scientific Publ.
    UID:
    b3kat_BV009660280
    Format: XI, 364 S. , Ill., graph. Darst.
    Edition: 1. publ.
    ISBN: 0632033444
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Lungenkrankheit ; Molekularbiologie ; Aufsatzsammlung
    Author information: Barnes, Peter J. 1946-
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  • 8
    Book
    Book
    London : Academic Pr.
    UID:
    b3kat_BV024562186
    Format: XI, 425 S.
    ISBN: 0120790203
    Series Statement: Food science and technology
    Language: Undetermined
    Keywords: Lipide ; Getreideprodukt
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  • 9
    UID:
    kobvindex_GFZ20190618133333
    Format: 40 Seiten , Illustrationen, 1 Karte
    Series Statement: CRREL Report 83-21
    Content: The probability density function of the gouge depths into the sediment is represented by a simple negative exponential over four decades of gouge frequency. The exceedance probability function is, therefore, e to the -lambda d, where d is the gouge depth in meters and lambda is a constant. The value of lambda shows a general decrease with increasing water depth, from 9/m in shallow water to less than 3/m in water 30 to 35 m deep. The deepest gouge observed was 3.6 m, from a sample of 20,354 gouges that have depths greater than or equal to 0.2 m. The dominant gouge orientations are usually unimodal and reasonably clustered, with the most frequent alignments roughly parallel to the general trend to the coastline. The value of N(bar) sub 1, the mean number of gouges (deeper than 0.2 m) per kilometer measured normal to the trend of the gouges, varies from 0.2 for protected lagoons to 80 in water between 20 and 38 m deep in unprotected offshore regions. The distribution of the spacings between gouges as measured along a sampling track is a negative exponential. The form of the frequency distribution of N sub 1 varies with water depth and is exponential for lagoons and shallow offshore areas, previously skewed for 10 to 20 m depths off the barrier islands, and near-normal for deeper water. As a Poisson distribution gives a reasonable fit to the N sub 1 distributions for all water depths, it is suggested that gouging can be taken as approximating a Poisson process in both space and time. The distributions of the largest values per kilometer of gouge depths, gouge widths, and the heights of the lateral embankment of sediments plowed from the gouges are also investigated.
    Note: CONTENTS Abstract Preface Introduction Background and environmental setting Data collection and terminology Data analysis Gouge depths Gouge orientation Gouge frequency Extreme value analysis Applications to offshore design Gouge depth Extreme value statistics Burial depths Conclusion Literature cited Appendix A: Detailed bathymetric map of the Alaskan portion of the Beaufort Sea
    In: CRREL Report, 83-21
    Language: English
    Keywords: Forschungsbericht
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  • 10
    UID:
    gbv_1025199944
    Format: xxviii 800 Seiten , illustrations, portraits, maps, facsimiles , 25 cm
    ISBN: 0859056759 , 9780859056755
    Note: Includes a genealogical guide to the Clifton family and a list of Australind's settlers and immigrants , Includes bibliographical references
    Language: English
    Keywords: Clifton, Marshall Waller 1787-1861 ; Geschichte 1840-1859 ; Briefsammlung
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