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  • 1
    Language: English
    In: The Open Magnetic Resonance Journal, 06/18/2010, Vol.3(1), pp.15-26
    Keywords: Physics;
    ISSN: 18747698
    Source: Bentham Science (via CrossRef)
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  • 2
    In: Journal of Analytical Atomic Spectrometry, 2011, Vol.26(2), pp.450-455
    Description: The demand to quantify the elemental composition of very small sample amounts and/or of samples which form artefacts during conventional sample preparations is increasing. Example applications are the quantification of engineered metal(loid) based nanomaterials in environmental samples, e.g. (i) the direct analyses of engineered nanoparticle (ENP) suspensions showing broad particle size distributions which are not suitable to be applied via the spray chamber in ICP-MS analyses, (ii) measurements of single invertebrates and tissue of selected organs which were exposed to ENPs, and (iii) whole plants or plant parts e.g. from Lemna sp. The use of imaging based high resolution methods like atomic force microscopy or environmental scanning electron microscopy creates the need to quantify the elemental composition of the visualised objects as directly and exactly as possible, at very low limits of detection. With this study the authors present a method/concept for the multi-element quantification of analytes from ENPs in complex matrices with different degrees of complexity by graphite furnace electrothermal vaporisation coupled to inductively coupled plasma quadrupole mass spectrometry equipped with collision/reaction cell (GF-ETV-ICP-QMS).
    Keywords: Demand ; Imaging ; Invertebrates ; Mathematical Analysis ; Matrices ; Matrix Methods ; Nanomaterials ; Nanoparticles ; Instruments and Measurements (So);
    ISSN: 0267-9477
    E-ISSN: 1364-5544
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  • 3
    Language: English
    In: The Open Magnetic Resonance Journal, 07/06/2010, Vol.3(2), pp.15-26
    ISSN: 18747698
    Source: Bentham Science (via CrossRef)
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  • 4
    Language: English
    In: Hydrological Processes, 15 August 2007, Vol.21(17), pp.2266-2275
    Description: The potential influence of pH on water repellency in soils has already been mentioned in some studies, but no clear correlation between these parameters has been found to date. In addition, although correlations of water content and water repellency have been found in numerous studies, the influence of drying and subsequent storage conditions on water repellency are still unclear. In this study, a series of samples showing water repellent and wettable conditions respectively at field moist states from two urban locations were compared regarding two main aspects: (i) the influence of artificial pH‐changes on their wetting behaviour and (ii) sample wettability changes during drying for different drying temperatures. The assumption made in a study by Hurraß and Schaumann (2006) on the same sample site, that differences in wettability of closely neighboured samples from one sample location can be interrelated with differences in pH, was confirmed. However, in contrast to the assumption that rising pH will improve the wettability and decreasing pH will intensify water repellency, we found a maximum in water repellency at a pH above the initial pH. The results from drying samples at different temperatures confirmed the dependence of water repellency development on the drying temperature. Additionally, we could confirm the conclusion from previous studies that the water content alone cannot explain the water content–WDPT (water drop penetration time) relationship. The results from drying and pH changes show that some location specific factors, like the number of pH active functional groups, may be relevant for sample wettability. As additional mechanism, which may be partly antagonistic to the influence of the water content, we assume temperature‐dependent conformational changes in SOM (Soil Organic Matter). It seems that aspects of these conformational changes may additionally be governed by pH in one of our two locations. Copyright © 2007 John Wiley & Sons, Ltd.
    Keywords: Soil Water Repellency ; Ph ; Drying Temperature ; Wdpt
    ISSN: 0885-6087
    E-ISSN: 1099-1085
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  • 5
    Language: English
    In: American Journal of Men's Health, July 2012, Vol.6(4), pp.266-272
    Description: The aim of this study was to analyze the rates of condom use among military and police populations in Peru, focusing on differences in use by type of partner. A Knowledge Attitudes and Practices survey was conducted among 6,808 military and police personnel in 18 Peruvian cities between August–September 2006 and September–October 2007. A total of 90.2% of the survey respondents were male; mean age was 37.8 years and 77.9% were married/cohabiting. In all, 99.5% reported having had sex; 89% of the participants had their last sexual contact with their stable partner, 9.7% with a nonstable partner, and 0.8% with a sex worker. Overall, 20.4% used a condom during their most recent sexual contact. Reasons for nonuse of condoms included the following: perception that a condom was not necessary (31.3%) and using another birth control method (26.7%). Prevention efforts against sexually transmitted diseases should focus on strengthening condom use, especially among individuals with nonstable partners.
    Keywords: Condom Use ; HIV/AIDS ; Military ; Risk Factors ; Sexually Transmitted Diseases/Infections ; Medicine ; Public Health
    ISSN: 1557-9883
    E-ISSN: 1557-9891
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  • 6
    Language: English
    In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, October 2011, Vol.20(10), pp.2222-31
    Description: The single-nucleotide polymorphism (SNP) 5p12-rs10941679 has been found to be associated with risk of breast cancer, particularly estrogen receptor (ER)-positive disease. We aimed to further explore this association overall, and by tumor histopathology, in the Breast Cancer Association Consortium. Data were combined from 37 studies, including 40,972 invasive cases, 1,398 cases of ductal carcinoma in situ (DCIS), and 46,334 controls, all of white European ancestry, as well as 3,007 invasive cases and 2,337 controls of Asian ancestry. Associations overall and by tumor invasiveness and histopathology were assessed using logistic regression. For white Europeans, the per-allele OR associated with 5p12-rs10941679 was 1.11 (95% CI = 1.08-1.14, P = 7 × 10(-18)) for invasive breast cancer and 1.10 (95% CI = 1.01-1.21, P = 0.03) for DCIS. For Asian women, the estimated OR for invasive disease was similar (OR = 1.07, 95%CI = 0.99-1.15, P = 0.09). Further analyses suggested that the association in white Europeans was largely limited to progesterone receptor (PR)-positive disease (per-allele OR = 1.16, 95% CI = 1.12-1.20, P = 1 × 10(-18) vs. OR = 1.03, 95% CI = 0.99-1.07, P = 0.2 for PR-negative disease; P(heterogeneity) = 2 × 10(-7)); heterogeneity by ER status was not observed (P = 0.2) once PR status was accounted for. The association was also stronger for lower grade tumors [per-allele OR (95% CI) = 1.20 (1.14-1.25), 1.13 (1.09-1.16), and 1.04 (0.99-1.08) for grade 1, 2, and 3/4, respectively; P(trend) = 5 × 10(-7)]. 5p12 is a breast cancer susceptibility locus for PR-positive, lower grade breast cancer. Multicenter fine-mapping studies of this region are needed as a first step to identifying the causal variant or variants.
    Keywords: Genetic Predisposition to Disease ; Breast Neoplasms -- Genetics ; Carcinoma, Ductal, Breast -- Genetics ; Carcinoma, Intraductal, Noninfiltrating -- Genetics ; Chromosomes, Human, Pair 5 -- Genetics ; Receptors, Progesterone -- Genetics
    ISSN: 10559965
    E-ISSN: 1538-7755
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  • 7
    Language: English
    In: BBA - Biomembranes, 2000, Vol.1468(1), pp.20-30
    Description: Bupivacaine, a local anesthetic and cationic amphiphile, forms stable liposomal-like structures upon direct mixing with plasmid DNA in aqueous solutions. These structures are on the order of 50–70 nm as determined by scanning electron microscopy, and are homogeneous populations as analyzed by density gradient centrifugation. The DNA within these structures is protected from nuclease degradation and UV-induced damage in vitro. Bupivacaine:DNA complexes have a negative zeta potential (surface charge), homogeneous nature, and an ability to rapidly assemble in aqueous solutions. Bupivacaine:DNA complexes, as well as similar complexes of DNA with other local anesthetics, have the potential to be a novel class of DNA delivery agents for gene therapy and DNA vaccines.
    Keywords: Bupivacaine ; DNA Delivery ; Local Anesthetic ; DNA Complex ; Genetic Immunization ; Chemistry
    ISSN: 0005-2736
    E-ISSN: 1879-2642
    E-ISSN: 00063002
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