Format:
Online-Ressource (362 p)
,
113 b&w, ill
Edition:
Online-Ausg. RSC eBook Collection 1968-2009
ISBN:
1847558275
,
9781847558275
Series Statement:
RSC biomolecular sciences [12]
Content:
This book provides a compelling overall update on current status of RNA interference, This book provides a comprehensive overview of the development of therapeutic oligonucleotides for therapeutic applications, touching on a number of additional oligonucleotides including a number of small interfering RNAs currently in various phases of clinical development. Written by leading expert scientists from both academia and leading biotechnical companies, the authors provide a compelling update on current status of RNA interference with emphasis on fascinating topics including oligonucleotides: antisense oligonucleotides, ribozymes, siRNAs, decoy oligonucleotides and aptamers. This exceptional work will be a valid resource for researchers and students as well as academia, consultants and scientists
Note:
Ebook
,
9780854041169; i_iv; v_viii; ix_xviii; 001_022; 023_042; 043_079; 080_102; 103_141; 142_162; 163_188; 189_199; 200_225; 226_240; 241_266; 267_295; 296_315; 316_328; 329_343
,
Chapter 1: The Role of Backbone Modifications in Oligonucleotide-Based Strategies-- Chapter 2: Genasense (G3139): An Antisense Bcl-2 Oligodeoxyribonucleotide with Substantial Clinical Activity and a Complex Mechanism of Action-- Chapter 3: Antisense Morpholino Oligomers and Their Peptide Conjugates-- Chapter 4: Peptide-PNA Conjugates for Modulation of Gene Expression-- Chapter 5: Locked Nucleic Acid: Properties & Therapeutic Aspects-- Chapter 6: Immune Stimulatory Oligonucleotides-- Chapter 7: Decoy Oligonucleotides to Treat Inflammatory Diseases-- Chapter 8: AS1411: Development of an Anticancer Aptamer-- Chapter 9: Spielgelmer NOX-E36 for Renal Diseases-- Chapter 10: Strategies for the Delivery of Oligonucleotides In Vivo-- Chapter 11: Lipid-Mediated in vivo Delivery of Small Interfering RNAs-- Chapter 12: Vector-Mediated and Viral Delivery of Short Hairpin RNAs-- Chapter 13: Development of an RNAi Based Gene Therapy against HIV-1-- Chapter 14: RNA Based Therapies for Treatment of HIV Infection.
Additional Edition:
Print version Therapeutic Oligonucleotides
Language:
English
Subjects:
Chemistry/Pharmacy
Keywords:
Oligonucleotide
;
Pharmakologie
;
Pharmakotherapie
;
Electronic books
URL:
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