UID:
edoccha_9961427361302883
Format:
1 streaming video file (35 min.) :
,
color, sound
,
003444
Note:
Retrieved April 16, 2024, from https://hstalks.com/bs/1202/.
,
Introduction -- Overview -- Single nucleotide polymorphisms (SNPs) -- SNPs: a prominent source of genetic variation -- Linkage disequilibrium -- SNP arrays -- Genotyping technologies -- DNA preparation method: Affymetrix -- DNA preparation method: Illumina -- High resolution SNP array types: Affymetrix -- High resolution SNP array types: Illumina -- DNA requirements -- Uses of SNP arrays in cancer -- Loss of heterozygosity (LOH): mechanisms -- Determining LOH -- Determining LOH without control DNA -- Sources of error in LOH measurements -- Summary: LOH -- Copy number changes in cancer -- Signal intensities example -- Using signal intensity -- Limitations to copy number estimates -- Allele-specific copy number changes -- Uses of allele-specific copy numbers -- Identifying germline alleles -- A risk locus in lung cancer -- Reasons to identify germline risk alleles -- Summary -- Acknowledgements.
Language:
English
Bookmarklink
