Format:
Online-Ressource
ISSN:
1860-7314
Content:
Potential applications of extracellular vesicles (EVs) are attracting increasing interest in the fields of medicine, cosmetics, and nutrition. However, the manufacturing of EVs is currently characterized by low yields. This limitation severely hampers progress in research at the laboratory and clinical scales, as well as the realization of successful and cost‐effective EV‐based products. Moreover, the high level of heterogeneity of EVs further complicates reproducible manufacturing on a large scale. In this review, possible directions toward the scalable production of EVs are discussed. In particular, two strategies are considered: i) the optimization of upstream unit operations and ii) the exploitation of well‐established and mature technologies already in use in other industrial bioprocesses.
In:
volume:14
In:
number:10
In:
year:2019
In:
extent:10
In:
Biotechnology journal, Weinheim : Wiley-VCH, [2006]-, 14, Heft 10 (2019) (gesamt 10), 1860-7314
Language:
English
DOI:
10.1002/biot.201800528
URN:
urn:nbn:de:101:1-2022071210133725959731
URL:
https://doi.org/10.1002/biot.201800528
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2022071210133725959731
URL:
https://d-nb.info/1262327342/34
URL:
https://doi.org/10.1002/biot.201800528
Bookmarklink
