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  • 1
    UID:
    almafu_9958058263402883
    Format: 1 online resource (232 p.)
    ISBN: 9783318003208 , 3318003204
    Series Statement: Contributions to microbiology ; vol. 2
    Content: Aspergillus fumigatus has become one of the most important fungal human pathogens in industrialized countries. It causes different diseases like allergic bronchopulmonary aspergillosis, aspergilloma, and invasive aspergillosis depending on the underlying disease as well as the immunological status of the host. A. fumigatus is today one of the most threatening aerial fungal pathogens because nosocomially acquired invasive aspergillosis typically occurs in the treatment setting for hematological malignancy. With the increasing number of immuno-compromised individuals such as AIDS and cancer patients or transplant recipients, systemic Aspergillus infections are often life-threatening with a very high mortality rate even after anti-mycotic therapy. This book provides a comprehensive overview of the classical and molecular techniques used in the isolation, analysis, diagnosis, and the identification of potential virulence factors of A. fumigatus. The pathogenesis and clinical presentation, the epidemiology and the therapy of A. fumigatus infections are discussed extensively. Compiling the most up-to-date information available, this volume will be a useful reference source for both clinical investigators and basic research scientists.
    Note: Description based upon print version of record. , ""Contents""; ""Preface""; ""Editorial Preface""; ""J.B. Georg W. Fresenius and the Description of the Species Aspergillus fumigatus""; ""The Genus Aspergillus with Special Regard to the Aspergillus fumigatus Group""; ""Pathogenesis and Clinical Presentation of Aspergillosis""; ""Epidemiology and Molecular Basis of the Involvement of Aspergillus fumigatus in Allergic Diseases""; ""Host Defense Mechanism in Aspergillus fumigatus Infections""; ""Antigen and DNA Patterns Characteristic of Aspergillus fumigatus""; ""Laboratory Diagnosis of Aspergillus fumigatus-Associated Diseases"" , ""Therapy of Aspergillus fumigatus-Related Diseases""""Animal Models of A. fumigatus Infections""; ""Problems of Antifungal in vitro Testing in Aspergillus fumigatus""; ""Transformation Systems of Aspergillus fumigatus""; ""Interactions between Aspergillus fumigatus and Host Matrix Proteins""; ""Aspergillus fumigatus-Secreted Proteases As Antigenic Molecules and Virulence Factors""; ""Chitin Synthase Genes of Aspergillus Species""; ""Pigment Biosynthesis and Virulence""; ""Author Index""; ""Subject Index"" , English
    Additional Edition: ISBN 9783805567145
    Additional Edition: ISBN 3805567146
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    UID:
    almafu_9961738648402883
    Format: 1 online resource (283 pages)
    Edition: 3rd ed. 2024.
    ISBN: 9783031648533 , 3031648536
    Series Statement: The Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research, 6
    Content: Estimates based on sequencing data suggest that there are around 5.1 million species of fungi. Yet only a small number of fungi are harmful to animals, including humans. In addition to host-pathogen interactions, there are also mutualistic interactions between fungi and animals. Diseases caused by pathogenic fungi range from allergic reactions and superficial infections to invasive mycoses, and have a significant impact on human and animal life. Fungi are also cultivated by animals as a food source in highly developed relationships or are even involved in gut mutualism. This 3rd edition of Volume 6 of The Mycota highlights exemplary interactions between fungal pathogens and their host(s). The book is organized in three parts: Part 1 summarizes our current understanding of important pathogenic fungi such as Candida species, Malassezia yeasts, Aspergillus fumigatus and fungi of the order Mucorales. Part 2 addresses the characterization of the host response towards pathogenic fungi. It focuses on RNA as a mediator of host-pathogen interactions, the human gut mycobiome, the role of the innate immune system in fighting infections, pattern recognition receptors involved in fungal infections, and a summary of established infection models for studying host-fungal-pathogen interactions. Part 3 provides insights into the impact transcriptomics and proteomics technologies have on the research of human-pathogenic fungi. The up-to-date reviews by experts in the field provide the reader with a comprehensive overview of the various research topics in the field of human and animal relationships with fungi and will hopefully help researchers to find inspiration for their own research.
    Note: Part I. Pathogens -- Chapter 1. Trinity of Environment, Animals, and Humans: A Résumé in the Case of the Fungal Order Mucorales -- Chapter 2. Pathogenicity Strategies of Candida Species During Interaction with Epithelial Cells -- Chapter 3. Malassezia Yeasts in Animals in the Next-Generation Sequencing Era -- Chapter 4. Extracellular Proteins and Their Roles in Aspergillus Fumigatus Pathogenesis -- Part II. Host-Pathogen Interaction -- Chapter 5. RNA as a Mediator of Host-Fungal Pathogenesis -- Chapter 6. The Human Gut Mycobiome and Its Potential as a Regulator of the Host’s Metabolic Health -- Chapter 7. The Host Innate Immune Response to Pathogenic Candida Albicans and Other Fungal Pathogens -- Chapter 8. Mammalian Pattern Recognition Receptors (Prrs) Involved in Recognition of Fungi -- Chapter 9. Infection Models for Human Pathogenic Fungi -- Part III. Techniques -- Chapter 10. Transcriptomic Analyses of Host Colonisation in Fungal Pathogens of Humans -- Chapter 11. Proteomics and Its Application to the Human-Pathogenic Fungus Aspergillus Fumigatus.
    Additional Edition: ISBN 9783031648526
    Additional Edition: ISBN 3031648528
    Language: English
    Keywords: Aufsatzsammlung
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Cover
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  • 3
    UID:
    gbv_1672336155
    Format: Online-Ressource
    Edition: Reproduktion Karger eBooks Collection 1997-2009
    ISBN: 3805567146 , 9783805567145 , 9783318003208
    Series Statement: Contributions to microbiology 2
    Content: Aspergillus fumigatus has become one of the most important fungal human pathogens in industrialized countries. It causes different diseases like allergic bronchopulmonary aspergillosis, aspergilloma, and invasive aspergillosis depending on the underlying disease as well as the immunological status of the host. A. fumigatus is today one of the most threatening aerial fungal pathogens because nosocomially acquired invasive aspergillosis typically occurs in the treatment setting for hematological malignancy. With the increasing number of immuno-compromised individuals such as AIDS and cancer patients or transplant recipients, systemic Aspergillus infections are often life-threatening with a very high mortality rate even after anti-mycotic therapy. This book provides a comprehensive overview of the classical and molecular techniques used in the isolation, analysis, diagnosis, and the identification of potential virulence factors of A. fumigatus. The pathogenesis and clinical presentation, the epidemiology and the therapy of A. fumigatus infections are discussed extensively. Compiling the most up-to-date information available, this volume will be a useful reference source for both clinical investigators and basic research scientists
    Note: Includes bibliographical references and indexes , ""Contents""; ""Preface""; ""Editorial Preface""; ""J.B. Georg W. Fresenius and the Description of the Species Aspergillus fumigatus""; ""The Genus Aspergillus with Special Regard to the Aspergillus fumigatus Group""; ""Pathogenesis and Clinical Presentation of Aspergillosis""; ""Epidemiology and Molecular Basis of the Involvement of Aspergillus fumigatus in Allergic Diseases""; ""Host Defense Mechanism in Aspergillus fumigatus Infections""; ""Antigen and DNA Patterns Characteristic of Aspergillus fumigatus""; ""Laboratory Diagnosis of Aspergillus fumigatus-Associated Diseases"" , ""Therapy of Aspergillus fumigatus-Related Diseases""""Animal Models of A. fumigatus Infections""; ""Problems of Antifungal in vitro Testing in Aspergillus fumigatus""; ""Transformation Systems of Aspergillus fumigatus""; ""Interactions between Aspergillus fumigatus and Host Matrix Proteins""; ""Aspergillus fumigatus-Secreted Proteases As Antigenic Molecules and Virulence Factors""; ""Chitin Synthase Genes of Aspergillus Species""; ""Pigment Biosynthesis and Virulence""; ""Author Index""; ""Subject Index""
    Additional Edition: ISBN 9783318003208
    Additional Edition: ISBN 9783805567145
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Aspergillus fumigatus ; Pathogenität ; Aspergillose
    Author information: Brakhage, Axel A. 1959-
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    UID:
    edocfu_9958058263402883
    Format: 1 online resource (232 p.)
    ISBN: 3-318-00320-4
    Series Statement: Contributions to microbiology ; vol. 2
    Content: Aspergillus fumigatus has become one of the most important fungal human pathogens in industrialized countries. It causes different diseases like allergic bronchopulmonary aspergillosis, aspergilloma, and invasive aspergillosis depending on the underlying disease as well as the immunological status of the host. A. fumigatus is today one of the most threatening aerial fungal pathogens because nosocomially acquired invasive aspergillosis typically occurs in the treatment setting for hematological malignancy. With the increasing number of immuno-compromised individuals such as AIDS and cancer patients or transplant recipients, systemic Aspergillus infections are often life-threatening with a very high mortality rate even after anti-mycotic therapy. This book provides a comprehensive overview of the classical and molecular techniques used in the isolation, analysis, diagnosis, and the identification of potential virulence factors of A. fumigatus. The pathogenesis and clinical presentation, the epidemiology and the therapy of A. fumigatus infections are discussed extensively. Compiling the most up-to-date information available, this volume will be a useful reference source for both clinical investigators and basic research scientists.
    Note: Description based upon print version of record. , ""Contents""; ""Preface""; ""Editorial Preface""; ""J.B. Georg W. Fresenius and the Description of the Species Aspergillus fumigatus""; ""The Genus Aspergillus with Special Regard to the Aspergillus fumigatus Group""; ""Pathogenesis and Clinical Presentation of Aspergillosis""; ""Epidemiology and Molecular Basis of the Involvement of Aspergillus fumigatus in Allergic Diseases""; ""Host Defense Mechanism in Aspergillus fumigatus Infections""; ""Antigen and DNA Patterns Characteristic of Aspergillus fumigatus""; ""Laboratory Diagnosis of Aspergillus fumigatus-Associated Diseases"" , ""Therapy of Aspergillus fumigatus-Related Diseases""""Animal Models of A. fumigatus Infections""; ""Problems of Antifungal in vitro Testing in Aspergillus fumigatus""; ""Transformation Systems of Aspergillus fumigatus""; ""Interactions between Aspergillus fumigatus and Host Matrix Proteins""; ""Aspergillus fumigatus-Secreted Proteases As Antigenic Molecules and Virulence Factors""; ""Chitin Synthase Genes of Aspergillus Species""; ""Pigment Biosynthesis and Virulence""; ""Author Index""; ""Subject Index"" , English
    Additional Edition: ISBN 3-8055-6714-6
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    UID:
    gbv_1604745029
    Format: XII, 221 S. , Ill., graph. Darst.
    ISBN: 3805567146
    Series Statement: Contributions to microbiology 2
    Note: Includes bibliographical references and indexes
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Aspergillus fumigatus ; Pathogenität ; Aspergillose ; Aufsatzsammlung
    Author information: Brakhage, Axel A. 1959-
    Author information: Schmidt, Axel 1962-
    Library Location Call Number Volume/Issue/Year Availability
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  • 6
    Online Resource
    Online Resource
    Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg
    UID:
    gbv_577107062
    Format: Online-Ressource (XXI, 296 S.) , Ill., graph. Darst.
    Edition: 2. ed.
    Edition: Online-Ausg. 2008 Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web
    ISBN: 9783540793076
    Series Statement: The mycota v. 6
    Note: Includes bibliographical references and indexes , Electronic reproduction; Available via World Wide Web
    Additional Edition: ISBN 9783540793069
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Mykotoxin ; Mykose ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    Author information: Brakhage, Axel A. 1959-
    Author information: Esser, Karl 1924-2019
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  • 7
    UID:
    gbv_744957478
    Format: Online-Ressource (XI, 284 p) , digital
    Edition: Springer eBook Collection. Chemistry and Materials Science
    ISBN: 9783540444060
    Series Statement: Advances in Biochemical Engineering 88
    Content: E.K. Schmitt, B. Hoff, U. Kück: Regulation of Cephalosporin Biosynthesis -- A.A. Brakhage, P. Spröte, Q. A.-Abdallah, A. Gehrke, H. Plattner, A. Tüncher: Regulation of Penicillin Biosynthesis in Filamentous Fungi -- J.F. Martin, R.V. Ullan, J. Casqueiro: Novel Genes Involved in Cephalosporin Biosynthesis: The Three-component Isopenicillin N epimerase System -- M.E. Evers, H. Trip, M.A. van den Berg, R.A.L. Bovenberg, A.J.M. Driessen: Compartmentalization and Transport in beta-lactam Antibiotics Biosynthesis -- N. Gunnarsson, A. Eliasson, J. Nielsen: Control of Fluxes Towards Antibiotics and the Role of Primary Metabolism in Production of Antibiotics -- M.S. Barber, U. Giesecke, A. Reichert, W. Minas: Industrial Enzymatic Production of Cephalosporin-Based beta-lactams -- H. von Döhren: Biochemistry and General Genetics of Nonribosomal Peptide Synthetases in Funghi.
    Note: E.K. Schmitt, B. Hoff, U. Kück: Regulation of Cephalosporin Biosynthesis -- A.A. Brakhage, P. Spröte, Q. A.-Abdallah, A. Gehrke, H. Plattner, A. Tüncher: Regulation of Penicillin Biosynthesis in Filamentous Fungi.- J.F. Martin, R.V. Ullan, J. Casqueiro: Novel Genes Involved in Cephalosporin Biosynthesis: The Three-component Isopenicillin N epimerase System.- M.E. Evers, H. Trip, M.A. van den Berg, R.A.L. Bovenberg, A.J.M. Driessen: Compartmentalization and Transport in beta-lactam Antibiotics Biosynthesis -- N. Gunnarsson, A. Eliasson, J. Nielsen: Control of Fluxes Towards Antibiotics and the Role of Primary Metabolism in Production of Antibiotics -- M.S. Barber, U. Giesecke, A. Reichert, W. Minas: Industrial Enzymatic Production of Cephalosporin-Based beta-lactams.- H. von Döhren: Biochemistry and General Genetics of Nonribosomal Peptide Synthetases in Funghi.
    Additional Edition: ISBN 9783540220329
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783642060359
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783540220329
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783662145326
    Language: English
    URL: Volltext  (lizenzpflichtig)
    Author information: Brakhage, Axel A. 1959-
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  • 8
    UID:
    kobvindex_ZLB13864026
    Format: X, 284 Seiten , Ill., graph. Darst. , 1 Beil.
    ISBN: 3540220321
    Series Statement: Advances in biochemical engineering, biotechnology 88
    Note: Text engl.
    Language: English
    Keywords: Cephalosporine ; Lactamantibiotikum 〈beta-〉 ; Chemische Synthese ; Biokatalysator ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
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  • 9
    UID:
    almahu_BV025777422
    Format: XXI, 296 S. : , Ill., graph. Darst.
    Edition: 2. ed.
    ISBN: 978-3-540-79306-9
    Note: Literaturangaben
    Language: English
    Subjects: Biology
    RVK:
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  • 10
    UID:
    almafu_BV025777422
    Format: XXI, 296 S. : , Ill., graph. Darst.
    Edition: 2. ed.
    ISBN: 978-3-540-79306-9
    Note: Literaturangaben
    In: The mycota.
    Language: English
    Subjects: Biology
    RVK:
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