Format:
Online-Ressource (XI, 70 p, online resource)
ISBN:
9783540371076
Series Statement:
Advances in Anatomy Embryology and Cell Biology 190
Content:
This monograph reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.
Content:
Reviews the biology of Neuregulins and their receptors. This monograph summarizes research, which has established crucial functions of this signaling system during development and disease
Note:
Includes bibliographical references (p. [47]-65) and index
,
CONTENTS; 1 Introduction: Molecular Control of Development; 2 Biology of the Neuregulin/ErbB Signaling Network; 2.1 Neuregulins and Their Receptors; 2.1.1 The Ligands; 2.1.2 ErbB Receptors; 2.1.3 Receptor Activation; 2.1.4 Signal Processing; 2.1.5 Crosstalk with Other Signaling Networks; 2.2 Developmental Functions of the Neuregulin-1/ErbB Signaling Pathway; 2.2.1 Neural Crest Cells and Their Derivatives; 2.2.1.1 Sympathetic Nervous System Development; 2.2.1.2 Schwann Cell Development; 2.2.1.3 Development of the Neuromuscular Junction; 2.2.2 Central Nervous System Development
,
2.2.3 Heart Development2.2.4 Development of the Mammary Gland; 2.3 Interacting Molecules-the Sox10/ErbB3 Connection; 2.3.1 ErbB3-Dependent Functions of Sox10; 2.3.2 Sox10 and Glial Cell Development; 2.4 NRG-1/ErbB Signals and Disease; 2.4.1 ErbB Receptors in Cancer and Heart Disease; 2.4.2 Neuregulin-1 and Susceptibility to Schizophrenia; 3 Summary; References; Subject Index
Additional Edition:
ISBN 9783540371052
Additional Edition:
Druckausg. Britsch, Stefan M. The Neuregulin-I/ErbB signaling system in development and disease Berlin : Springer, 2007 ISBN 9783540371052
Additional Edition:
ISBN 3540371052
Language:
English
Subjects:
Biology
Keywords:
Neureguline
;
Epidermaler Wachstumsfaktor-Rezeptor
;
Signaltransduktion
;
Entwicklung
;
Neureguline
;
Epidermaler Wachstumsfaktor-Rezeptor
;
Signaltransduktion
;
Pathophysiologie
DOI:
10.1007/978-3-540-37107-6
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