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  • 1
    Online Resource
    Online Resource
    Totowa, NJ : Humana Press
    UID:
    b3kat_BV035263132
    Format: 1 Online-Ressource (XVII, 618 S.) , Ill., graph. Darst.
    Edition: Online-Ausgabe Springer ebook collection. Medicine 2005-2008
    ISBN: 9781597450805
    Series Statement: The receptors
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 1-58829-568-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-1-58829-568-2
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
    RVK:
    RVK:
    Keywords: Serotoninrezeptor ; Molekularpharmakologie ; Physiologie ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press,
    UID:
    almahu_BV035263132
    Format: 1 Online-Ressource (XVII, 618 S.) : , Ill., graph. Darst.
    Edition: Online-Ausgabe Springer ebook collection. Medicine 2005-2008
    ISBN: 978-1-59745-080-5
    Series Statement: The receptors
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 1-58829-568-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-1-58829-568-2
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
    RVK:
    RVK:
    Keywords: Serotoninrezeptor ; Molekularpharmakologie ; Physiologie ; Aufsatzsammlung ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Online Resource
    Online Resource
    Totowa, N.J. :Humana Press,
    UID:
    edoccha_9958074056302883
    Format: 1 online resource (637 p.)
    Edition: 1st ed. 2006.
    ISBN: 1-280-83213-4 , 9786610832132 , 1-59745-080-4
    Series Statement: The receptors
    Content: The recent cloning and identification of a large number of serotonin (5-HT) receptors-a major family of therapeutic targets-holds out the possibility of developing novel, subtype-selective 5-HT receptor agonists and antagonists for use as psychiatric, cardiovascular, and neurological medications. In The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics, leading experts comprehensively examine our current understanding of the molecular and structural biology of 5-HT receptors and their pharmacological use. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction. Comprehensive and state of the art, The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics provides an illuminating "snapshot" of the 5-HT receptor field today and prospects for the future, taking it from the genomic to a systems level of understanding.
    Note: Description based upon print version of record. , Molecular Biology and Genomic Organization of G Protein-Coupled Serotonin Receptors -- Structure and Function Reveal Insights in the Pharmacology of 5-HT Receptor Subtypes -- Polymorphic and Posttranscriptional Modifications of 5-HT Receptor Structure -- Strategies for the Development of Selective Serotonergic Agents -- 5-HT Receptor Signal Transduction Pathways -- Agonist-Directed Trafficking of 5-HT Receptor-Mediated Signal Transduction -- Identification of 5-HT2 and 5-HT4 Receptor-Interacting Proteins -- 5-HT Receptor-Associated Proteins (FRAPs) -- Cellular and Subcellular Localization of Serotonin Receptors in the Central Nervous System -- Chemical Neuroanatomy of 5-HT Receptor Subtypes in the Mammalian Brain -- Modulation of the Neuronal Activity and Neurotransmitter Release by 5-HT1A and 5-HT1B/1D Receptors -- Electrophysiology of 5-HT2A Receptors and Relevance for Hallucinogen and Atypical Antipsychotic Drug Actions -- The Emergence of 5-HT2B Receptors as Targets to Avoid in Designing and Refining Pharmaceuticals -- The 5-HT3 Receptor -- 5-HT3 and 5-HT4 Receptors as Targets for Drug Discovery for Dementia -- Electrophysiological Properties of G?s-Coupled 5-HT Receptors (5-HT4, 5-HT6, 5-HT7) -- 5-HT6 Receptors as Targets for the Treatment of Cognitive Deficits in Schizophrenia -- 5-HT7 Receptors as Favorable Pharmacological Targets for Drug Discovery -- Serotonin System Gene Knockouts -- Effects of Serotonin-Related Gene Deletion on Measures of Anxiety, Depression, and Neurotransmission. , English
    Additional Edition: ISBN 1-61737-647-7
    Additional Edition: ISBN 1-58829-568-0
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press,
    UID:
    edocfu_BV035263132
    Format: 1 Online-Ressource (XVII, 618 S.) : , Ill., graph. Darst.
    Edition: Online-Ausgabe Springer ebook collection. Medicine 2005-2008
    ISBN: 978-1-59745-080-5
    Series Statement: The receptors
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 1-58829-568-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-1-58829-568-2
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
    RVK:
    RVK:
    Keywords: Serotoninrezeptor ; Molekularpharmakologie ; Physiologie ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press,
    UID:
    edoccha_BV035263132
    Format: 1 Online-Ressource (XVII, 618 S.) : , Ill., graph. Darst.
    Edition: Online-Ausgabe Springer ebook collection. Medicine 2005-2008
    ISBN: 978-1-59745-080-5
    Series Statement: The receptors
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 1-58829-568-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-1-58829-568-2
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
    RVK:
    RVK:
    Keywords: Serotoninrezeptor ; Molekularpharmakologie ; Physiologie ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
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