Format:
1 Online-Ressource (XXVI, 1318 p)
,
Num. figs
Edition:
Reprint 2020
Edition:
[Online-Ausgabe]
ISBN:
9783112330029
Content:
Frontmatter -- Foreword -- Contents -- Chemistry, Structure, Function and Biological Assay -- Introduction -- Synthesis of Some Side Chain Analogues of Vitamin D3 Metabolites -- Structural Transformations on Vitamin D -- Distribution and Activity of a Vitamin D3 Compound in Trisetum Flavescens -- Synthesis and Biological Activity of 24R-Hydroxy-25-fluorocholecalciferol and 1a, 24R-Dihydroxy-25-fluorocholecalciferol -- The Synthesis and Biological Evaluation of Fluorinated Analoges as Probes of Vitamin Da Metabolism -- 19-Substituted-10,19-Dihydrovitamins via Hydrozirconation of Vitamin D3 -- The Synthesis of 1a, 3a-Dihydroxy-25Methylcholesta-5,7-Diene-24-OIC Acid, and of la, 3a-Dihydroxy-25 Methylcholesta-5,7-Diene -- Interconversion of Vitamin D and Trans-Vitamin D by Triplet-Sensitized Isomerization -- The Use of UV, CD, 2H-NMR Spectroscopy and Mass Spectrometry for the Investigation of Conformational Mobility of Vitamin D and Previtamin D and their Interconversion -- 25 (R), 26 and 25 (S), 26-(OH)2D3: Biological Activity in Intact and Nephrectomized Rats. Comparative Effects of 1, 25, 24 (R), 25-(OH)2D3 and I, 24 (R), 25-(OH)3D3 -- Inhibitors of Vitamin D Metabolism and Action -- C(1)-Hydroxylation of Vitamin D3 and Related Compounds -- Vitamin D3 Sulfate in Lactating normally fed Rats and Suckling Pups After Maternal Administration of 3H Vitamin D3 or 35S Vitamin D3 Sulfate -- Synthesis of Vitamin D Analogues and their Covalent Binding to Affinity Chromatographic Media -- Osteoporosis -- Calcium Absorption and Plasma 1,25 (OH)2D Levels in Post-Menopausal Osteoporosis -- Osteoporosis and Age-Related Osteopenia: Evaluation of Possible Role of Vitamin D Endocrine System in Pathogenesis of Intestinal Calcium Absorption -- Two Years Experience of Oral Treatment with 1a-Hydroxyvitamin D and Calcium in Patients with Senile or Postmenopausal Osteoporosis -- The Treatment of Osteoporosis with 24,25 Dihydroxycholecalciferol A Pilot Study -- Osteomalacic Factors in the Osteoporosis and the Treatment of Osteoporotic Patients with Vitamin D2 and 1aOHD3 -- Transcalciferan/D-Binding Protein(s) -- Biologic Significance of Genetic Variation in Human Gc (Vitamin D-Binding Protein) -- The Transport of Vitamin D -- Structure and Properties of Human Plasma Vitamin D Transport Protein (Group-Specific Component) -- Serum Vitamin D Binding and Gc Polymorphism -- Sunlight, Skin and Seasonal Effects -- Identification of in Vivo Generated Previtamin D3, Vitamin D3 and 25-Hydroxyvitamin D3 in the Vitamin D-Deficient Rats Irradiated by Ultraviolet Light -- Response of Plasma 250HD to Standardized Ultra Violet Radiation -- Effects of Sunlight Exposure on Blood Concentration of Vitamin D Derivatives in Healthy Japanese Adults -- Contribution of Skin Vitamin D3 Synthesis in Patients Receiving Total Parenteral Nutrition -- The Photo-Biochemistry of Vitamin D3 in Vivo in the Skin -- Assays for Vitamin D Metabolites -- Measurement of Plasma 1,25 (OH)2 Vitamin D by Protein Binding Assay and Radioimmunoassay -- Use of Isotope Dilution Mass Fragmentography in Vitamin D Research -- Assay of 1,25-Dihydroxyvitamin D and Other Active Vitamin D Metabolites in Serum: Application to Animals and Humans -- 24,25-Dihydoxyvitamin D in Human Serum -- Radioimmunoassay of Vitamin D Metabolites -- Assays for Vitamin D and its Metabolites -- Radioimmunoassay for Circulating 1,25- and 25,26-Dihydroxycholecaliferols in Man -- Hemisuccinates of Vitamin D3 and of its Metabolites -- Studies on Antisera against Vitamin D Metabolites -- The Measurement of Various Vitamin D Derivatives in Plasma Using High-Pressure Liquid Chromatography -- Assay of 1,25- and 24,25 Dihydoxycholecalciferol in Human Serum - some Technical Considerations -- Radiocompetitive Protein Binding Assays for 25-Hydroxy Vitamin D, 24,25-Dihydroxyvitamin D and 1,25-Dihydroxy-vitamin D in Human Serum -- Steroid Receptors: What do We not Know? -- Vitamin D - Parathyroid Hormone -- Cholecalcifediol suppression of PTH Secretion from Monolayer Culture of Human Parathyroid Carcinoma Cells -- The Effect of Human Growth Hormone Replacement on Parathyroid Function and Vitamin D Metabolism -- Serum Calcium Concentration: Possible Regulator of Renal Parathyroid Hormone Action -- Effects of Vitamin D3 Metabolites Injection into Thyro-parathyroidectomized Pregnant Rats on Fetal Weight and Liver Glycogen Stores in Mothers and Fetuses -- Effects of Vitamin Deficiency on Calcium-Binding Proteins and on Plasma Calcitonin and Parathyroid Hormone Levels in Growing Pigs -- 1,25 Dihydroxycholecalciferol effect on in Vitro Immunoreactive Human Parathyroid Hormone Secretion from Hyperplastic Glands -- Quantitative Changes of Rat Thyroid C Cell Population in Hyper- and Hypovitaminosis D -- The Interactions Between Vitamin D Metabolites, Parathyroid Hormone and Calcitonin -- In Vivo Suppression of Parathyroid Hormone Secretion by 24,25 Dihydroxy Cholecalciferol in Hyperparathyroid Dogs -- Renal Actions -- Acute and Chronic Effects of Vitamin D Metabolites on the Renal Handling of Phosphate -- Interaction of Vitamin D Metabolites with Parathyroid Hormone and Vasopressin -- Phosphaturie Effect of Parathyroid Hormone in Phosphate Depleted Man -- Vitamin D in Maternal, Fetal and Neonatal Conditions -- Long Term Effects of Low 25-Hydroxyvitamin D (25-OHD) Serum Concentrations in Premature infants: A Preliminary Report -- Vitamin D, Calcium and Phosphorus Requirements and Bone Mineralization in Preterm Infants -- The Transplacental Movement of Metabolites of Vitamin D in the Sheep -- The Effects of Solanum Glaucophyllum Ingestion by Pregnant Cows on Plasma Calcium Levels in Dams, Fetuses and Neonates and on the Mineral Composition of Colostrum -- The Vitamin D3 Requirement for Premature Infants -- Calcium Uptake and Binding by Membrane Fractions of Human Placenta: ATP Dependent Calcium Accumulation -- Skeletal Actions -- Influence of 1,25(OH)2D3 on Bone Surface Lining Cells and on cartilage mineralisation in vitro.
Content:
Ultrastructural studies -- The Role of Vitamin D Metabolites in Calcification of Chicken Epiphysis -- Bone Mineral Solubility and its Alteration by 1,25-Dihydroxyvitamin D3 -- Accelerated Bone Formation in End Stage Renal Disease -- 24,25-Dihydroxyvitamin D: The Preferred Metabolite for Bone -- Cellular Location and Regulation of the 24,25-Dihydroxyvitamin D3 Formation in Cultured Cells from Bone and Cartilage -- Comparison of the Histological Effect and Metabolism of 25-(OH)D and 1,25-(OH)2D in Rat Bone -- Action of Solanum Malacoxylon on Bone Histology of Vitamin D Deficient Rats -- Dual Action of Parathyroid Hormone on the Mineralization of Rat Incisor Dentin -- Influence of Diet on the Response of Bone Cells to 1,25-OH)2D3 in Thyroparathyroidectomized Rats -- Nuclear Binding of 24,25-(OH)2D3 and its Effect on DNA Polymerase Activities in Cultured Chondrocytes -- Effects and Interaction of 1,25 (OH)2Ds and 24,25 (OH)2D3 on Bone -- Effects on Mineral Homeostasis of 1,25 (OH)2D3 and 24,25 (OH)2D3, Alone and in Combination, in Rats -- Effect of Dihydroxylated Vitamin D Metabolites on Experimental Rickets -- Evidence for the Presence of 25-OH-D3 Binding Proteins in Embryonic Cartilage -- Glucocorticoid Dependence of Cytosol 1,25-Dihydroxycholecalciferol Receptors in Fetal Rat Calvaria -- Vitamin D Metabolism -- Recent Developments in the Metabolism of Vitamin D -- The Role of Systemic PH in the Bioactivation of Vitamin D -- The Site of Synthesis of 1,25(OH)2 Vitamin D3 in the Kidney A Microenzymatic Assay on Isolated Tubules -- Response of Chick Kidney Cell Cultures to 1,25-Dihydroxyvitamin D3 -- Growth Hormone and Prolactin Action on Vitamin D Metabolism in the Rat -- Effective Liver 25-Hydroxylation of Vitamin D under Chronic Ethanol Administration in the Rat -- Calcium Transport by Rat Colon: Response to 1a,25(OH)2D3 and Dietary Calcium Restriction -- Direct Vitamin D3-Metabolite Regulation of Kidney 25-Hydroxyvitamin D3 Metabolism -- The Regulation of 25-Hydroxylation by Vitamin D Intake in Man: A Theoretical Model -- Minimal Deprivation of Vitamin D Enables Parathyroid Hormone to Stimulate 25-OH Vitamin D - 1a-Hydroxylase -- Vitamin D Metabolism in Japanese Quail: Effects of Lead Exposure and Dietary Calcium -- Evidence for a Calcium-Dependent, PTH-lndependent Regulation of Plasma 1,25-Dihydroxyvitamin D in Rats -- Computer Modeling of Vitamin Metabolism -- Prolactin, Growth Hormone and Vitamin D Metabolism -- A Study of the Physiologic Significance of 24-Hydroxylation of 25-Hydroxyvitamin D -- Dynamic Aspects of Vitamin D Metabolism: Formation of Hydroxylated Metabolites from A Physiological Dose of Cholecalciferol in Vitamin D Depleted Man -- The Regulation of Plasma 1,25-(OH)2-D Concentrations in Healthy Adults -- The Role of the Liver in the Control of Vitamin D Metabolism -- Prostaglandins and 25-Hydroxyvitamin D-1a-Hydroxylase -- Regulation of Plasma Levels of 1,25 Dihydroxy Vitamin D in Growing Dogs with Thyroparathroidectomy and Varying Amounts of Parathyroid Hormone -- Both 24R,25-Dihydroxyvitamin D3 and 1a,25-Dihydroxyvitamin D3 are Indispensable for Normal Calcium and Phosphorus Homeostasis -- New Renal Metabolites of 24,25-Dihydroxyvitamin Ds in the Chick -- The 1a- and 24-Hydroxylases of 25-Hydroxycholecalciferol: one or two Enzymes? -- Regulation of 25-Hydroxycholecalciferol-1 and -24-Hydroxylases in Cultured Kidney Cells -- Possible Extra-Renal 25-OHD3-1a-Hydroxylase Activity in the Pregnant Rat -- The Absorption and Metabolism of Vitamin D3 from Parenteral Injection Sites -- 1,25-(OH)2 Vitamin D3 & 24,25-(OH)2 Vitamin D3 Synthesis by the Isolated Perfused Rat Kidney -- In Vitro Regulation of 25-Hydroxyvitamin D3 Metabolism by Avian Kidney Cells in Serum-Free Medium -- Comparative Studies on Mitochondrial and Microsomal NADPH-Cytochromec Reductases of Chick Tissues -- Effect of Pregnancy, Acromegaly, Primary Hyperparathyroidism and Prolactinoma on 1,25-Dihydroxyvitamin D in Man -- Relationship of Dietary Phosphorus Restriction to Calcium Absorption and Vitamin D Metabolism -- Intestinal Actions and Calcium Binding Protein: Meaning of Non-Parallel 1,25-Dihydroxycholecalciferol Mediated -- Response Relationship in Intestine and Bone to Dose and Time -- Cytoplasmic Localization of the Calcium Binding Protein in Rat Duodenal Absorptive Cells -- Visualization of Vitamin D-Dependent Calcium Binding Protein in Chick Intestine by Immuno-Scanning Electron Microscopy -- Influence of High Doses of Vitamin D3 on Broilers and Adult Hens -- Purification of the Intestinal Receptor for 1,25-Dihydroxyvitamin D -- Recent Progress on the Application of Affinity and Covalent Chromatography to the Purification of the 1,25-Dihydroxyvitamin D3 Receptor from Chick Intestinal Mucosa -- 1,25-Dihydroxycholecalciferol and the Prevention of Parturient Hypocalcemia and Paresis ("Milk Fever") in Pregnant Dairy Cows -- A Vitamin D-Induced, Calcium-Binding Protein from Rat Intestinal Brush Border -- Relationship of Intestinal Calcium Absorption to Intestinal and Plasma Calcium Binding Protein Measured by a Radioimmunoassay -- The Effect of 1,25-Dihydroxycholecalciferol and Hydrocortisone on the Development of the Embryonic Chick Duodenum -- Theories on the Mechanism of Action of 1,25(OH)3D3 on Active Intestinal Calcium and Inorganic Phosphate Absorption: are the Calcium and Phosphate Transport Processes Coupled, Uncoupled or Both? -- Fundamental Actions of 1,25 Dihydroxycholecalciferol on Intestinal Ion Transport do not Involve Gene Activation -- The Effect of Cholecalciferol on the Phosphorylation of Intestinal Membrane Proteins -- Some Biochemical Responses of Chick Intestine to 1,25- Dihydroxyvitamin D -- Induction of Metallothionein(s) in Organ-Cultured Duodenum: Relationship to 1a,25-(OH)2D3-lnduced CaBP Synthesis -- Vitamin D and Calcium Absorption: Computer Simulation -- Renal Osteodystrophy -- Clinical Assessments of Vitamin D3 - Therapy in Patients on Longterm Haemodialysis -- Adverse Effects of Vitamin D Metabolites on Osteitis Fibrosa in Patients on Chronic Hemodialysis: Critical Role of Induced Hyperphosphatemia -- Assessment of Long-Term Effects of 1a(OH)D3 on PTH Secretion, Intestinal Calcium Absorption and Bone in Chronic Renal Failure -- Hypergonadotropic Hypogonadism in Renal Failure - A Defect Responsive to 1,25(OH)2D3 -- Comparative Effects of 1,25-Dihydroxycholecalciferol and Cholecalciferol in non-Dialyzed Chronic Renal Failure -- Medium term Effects of 1,25-Dihydroxy-vitamin D in Patients with Renal Osteopathy -- The Early Detection and Treatment of Renal Osteodystrophy -- The Combined Use of Human Calcitonin and 1,25-Dihydroxycholecalciferol in the Treatment of Renal Osteodystrophy -- Intestinal Calcium Transport in Vitro as Influenced by Azotemia, Dietary Calcium, Parathyroidectomy and 1,25-Dihydroxycholecalciferol (1,25-DHCC) Treatment.
Content:
- Role of Calcium - ATPase -- Recurrence of Hyperparathyroidism from Autografted Parathyroid Fragments in Uremic Patients in Spite of Administration of 25(OH)D3 and 1a(OH)D3 -- 25 Hydroxycholecalciferol Plasma Levels in Anephric Patients After Oral Loading of Vitamin D -- The Histological Study on Experimental Renal Osteodystrophy in Rats -- Long Term Effects of Small Doses of 1,25 Dihydroxycholecalciferol in Dialysis Patients -- Clinical and Biological Efficiency of 1,25 Dihydrocholecalciferol in Chronic Dialysis Patients with Renal Osteodystrophy -- Histomorphometric Evaluation of the effect of 1,25-DHCC in Type II and III of Renal Bone Disorders -- Histomorphometry of Bone Changes in Renal Osteodystrophy After Treatment with 1,25-Dihydroxycholecalciferol -- The use of 5,6-trans-25-OH-Cholecalciferol in the Treatment of Patients with Fully Developed Renal Osteopathy Requiring Dialysis: Therapeutical Application and Treatment Results -- Clinical Experience in Long Term Treatment with 1,25-DHCC in Different Histological Forms of Renal Osteopathy -- Calcium-Phosphorus Metabolism and Renal Function During 1a-OH-D3 Vitamin Treatment of Patients with Chronic Renal Disease -- Newcastle Bone Disease -- The Measurement of 1,25-(OH)2-D by Competitive Protein Binding Assay in the Plasma of Anephric Patients: The Effects of Dihydrotachysterol Therapy -- 25-Hydroxycholecalciferol and 1,25 Dihydroxycholecalciferol in the Treatment of Renal Osteodystrophy -- Bone Histomorphometry in Children with Early Chronic Renal Failure Treated with 25 (OH)D3 -- Hypercalcemia During Treatment of Uremic Patients with 1,25(OH)2D3: Analysis of 43 Cases -- Renal Bone Disorder in Children: Therapy with Vitamin D3 or 1,25- Dihydroxycholecalciferol -- Treatment of Predialysis Renal Bone Disease with 1a-(OH) Vitamin D3 and 1.25-(OH)2 Vitamin D3. Initial Results of Balance Studies and the Effect on Intestinal Calcium Absorption, Serum PTH and Calcitonin Levels -- The Effect of 1-a-OHD3 on Bone Changes in Non-Dialysed Patients with Chronic Renal Insufficiency -- 25 Hydroxyvitamin D in Renal Osteodystrophy: Long Term Results of A Six-Center Trial -- Further Therapeutical Experience with the Vitamin D Analog 5,6-trans-25-OHCC in Renal Osteopathy -- A New Laboratory Model for Renal Osteodystrophy and Vitamin D -- The Influence of Uremia, Aluminiumhydroxide and Various Vitamin D Compounds on the Course of Nutritional Rickets in Rats -- Effect of Vitamin D Analogs in Rats with Experimental Renal Osteodystrophy -- Evaluation of Histological Procedures in the Investigation of Bone Disease Related to Vitamin D -- Pathophysiology of Vitamin D Related Diseases -- Effects of in Vitro and in Vivo Sodium Restriction on Corticosteroidinduced Intestinal Calcium Malabsorption -- Trisetum Calcinosis: Current Status of Clinical Research -- X-Linked Hypophosphatemia is a Disorder of Phosphate Transport in the Renal Brush Border Membrane in the Hypophosphatemic Mouse. Why is Serum 1,25-(OH)2D Low in the Human Homologue? -- The Effect of Vitamin D3 and Metabolites on Magnesium Metabolism -- Subnormal Serum 1,25-Dihydroxyvitamin D3 Levels in Children with Glomerular Disease Receiving Corticosteroids -- Regulation of Serum Phosphorus by 1,25(OH)2D3 -- Unexplained hypercalcemia:? Sarcoidosis sine Sarcoidosis: with Elevated Serum Level of 1,25 DHCC -- Vitamin D Metabolites in Hypercalcitoninemic States -- Target Cell Resistance in Pseudohypoparathyroidism: Single or Multiple? -- Vitamin D Metabolism In Patients with Nephrolithiasis -- Evidence for Abnormal Metabolism of Vitamin D in Sarcoidosis -- Effects of Experimental Diabetes in the Rat on Calcium Transport and Vitamin D Metabolism -- Absorption of Vitamin D and 25-OH Vitamin D in patients with Intestinal Malabsorption -- Effect of Diabetes in Rats on the Metabolism of Cholecalciferol and 25-Hydroxycholecalciferol -- Do Alkaline Phosphatases Have a Physiological Function? -- Clinical Application of the 1,25-(OH)2D Assay -- Elevated Plasma 1,25-(OH)2D Following Massive Dosing of Vitamin D3 in Dairy Cattle -- Vitamin D Metabolism in the Diabetic Rat -- The Effect of Chronic Excess or Deficiency of Growth Hormone on Plasma 1,25-Dihydroxyvitamin D Levels in man -- 25-Hydroxylation of Vitamin D in the Elderly -- Intestinal Absorption of Radiophosphate After Physiological Doses of 1,25-Dihydroxyvitamin D in Normals and Pathological Conditions -- Calcium Metabolism Following Proximal Gastric Vagotomy in Man -- 25-Hydroxyvitamin D Metabolism in Nontropical Sprue -- Circulating Vitamin D Metabolites in A Hypoparathyroid Patient Resistent to Vitamin D -- The Ability of 1a, 25-Dihydroxycholecalciferol to Alter the Fatty Acid Composition of Phosphoglycerides in Rat Intestinal Mucosa and Smooth Muscle -- Vitamin D Dependent Clinical Disorders - Bone Disease : Clinical Aspects - Unanswered Questions in Renal Osteodystrophy - Problems of Vitamin D Nomenclature - Addendum -- Author Index -- Subject Index -- Backmatter
Note:
Mode of access: Internet via World Wide Web.
,
In English
Additional Edition:
9783112330012
Additional Edition:
Erscheint auch als print 9783112330012
Language:
English
DOI:
10.1515/9783112330029
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