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Format: XIII, 212 Seiten , Ill., graph. Darst.

ISBN: 9781461402039

Series Statement: Advances in experimental medicine and biology 719

Language: English

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Format: Online-Ressource (XIII, 212p. 29 illus., 18 illus. in color, digital)

Edition: 1

ISBN: 9781461402046

Series Statement: Advances in Experimental Medicine and Biology 719

Content: Andrew J. Pollard

Content: This book covers course with topics in infectious diseases in children and is intended for Pediatric Infectious disease clinical researchers, trainees, trainers, and all those who manage the research of children with infections and the children themselves. The conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc. ToC reflects the scientific program found at our associated website

Note: Description based upon print version of record , Hot Topics in Infection and Immunity in Children VIII; Preface; Acknowledgments; Contents; Contributors; Our Time of Pestilence: Purchasing Immunity and Ignoring the Misery of Others; 1 Prisoners of Life; 2 Purchasing Health; 3 The Deceptive Language of Risk; 3.1 The Obesity Epidemic; 3.2 Influenza and Pandemic Risk; 4 Beware the Forecast Epidemic; References; Neonatal Meningitis: Can We Do Better?; 1 Incidence; 2 Aetiology; 3 Mortality and Morbidity; 4 Presentation; 5 Diagnosis; 5.1 Should an LP Only Be Performed on Symptomatic Babies? , 5.2 Should an LP Be Performed Only When Blood Cultures are Positive?5.3 Making the Diagnosis; 5.4 Other Diagnostic Issues; 5.5 Does a Delay in the Laboratory Evaluation of the CSF Affect the Results?; 5.6 What Influences the Success of Obtaining an LP?; 6 Management; 6.1 Empiric Antibiotics; 6.2 Empiric Cover for Listeria Infection; 7 What are the Predictors for a Poor Outcome?; 8 Improving the Outcome of Neonatal Meningitis; 8.1 What is the Role of New or Different Antibiotics in the Management of Neonatal Bacterial Meningitis? , 8.2 What is the Role of Other Adjunctive Therapy in the Management of Bacterial Meningitis?8.2.1 What is the Role of Immunoglobulin in Neonatal Bacterial Sepsis/Meningitis?; 8.2.2 G- or GM: CSF; 8.2.3 The Use of Corticosteroids in Meningitis; 8.2.4 What About Oral Glycerol?; 9 Prevention; 10 Conclusions; 10.1 Improving the Outcome of Neonatal Meningitis…Can We Do Better?; References; Approaches Towards Avoiding Lifelong Antiretroviral Therapy in Paediatric HIV Infection; 1 Introduction; 2 How does Paediatric HIV Infection Differ from Adult Infection? , 2.1 Rate of Disease Progression, Timing of Infection2.2 Immune Activation and HIV Disease Progression; 2.3 Control of HIV viraemia; 2.4 Thymic Activity; Immune Reconstitution on ART; 3 CD8+ T-Cell Mediated Immune Control of HIV; 3.1 CD8+ T-Cell Mediated Immune Control of HIV in Adults; 3.2 CD8+ T-Cell Mediated Immune Control of HIV in Children; 4 ART Interruption Studies; 4.1 ART Interruption Studies in HIV-Infected Adults; 4.2 ART Interruption Studies in HIV-Infected Children; 5 Conclusion; References; How Short Is Long Enough for Treatment of Bone and Joint Infection?; 1 Introduction , 2 Role of Antimicrobials3 Risk of Reoccurrence; 4 Monitoring the Course of OM, SA, and OMSA; 5 Towards Shorter Antimicrobial Courses; 6 Lessons Learned from Prospective Studies in OM, SA, and OMSA; References; What's New in Diagnostic Testing and Treatment Approaches for Mycoplasma pneumoniae Infections in Children?; 1 Introduction; 2 Epidemiology of Mycoplasma Respiratory Infections; 3 Clinical Presentation and Basis for Pathogenesis; 3.1 Respiratory Disease; 3.2 Extrapulmonary Manifestations; 4 Diagnostic Approach; 4.1 Culture; 4.2 Serology; 4.3 Nucleic Acid Amplification Tests , 5 Macrolide Resistance and Treatment Alternatives

Additional Edition: ISBN 9781461402039

Additional Edition: Buchausg. u.d.T. ISBN 978-1-461-40203-9

Language: English

Subjects: Medicine

DOI: 10.1007/978-1-4614-0204-6

URL: Volltext

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URL: Cover

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Format: Online-Ressource (XIV, 318p. 47 illus., 22 illus. in color, digital)

ISBN: 9781441971852

Series Statement: Advances in Experimental Medicine and Biology 697

Content: Course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections.

Content: This course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections

Note: Description based upon print version of record , Preface; Acknowledgments; Contents; Contributors; The Value of Vaccination; References; Recent Trends in Global Immunisation; References; New Advances in Typhoid Fever Vaccination Strategies; References; Prevention of Vertical Transmission of HIVin Resource-Limited Countries; References; Pneumonia in Children in Developing Countries; References; Darwin, Microbes and Evolution by Natural Selection; References; Human Herpesvirus 6; References; Advances in the Diagnosis and Management of Central Venous Access Device Infections in Children; References , Moraxella catarrhalis -- Pathogen or Commensal?References; Anaerobic Infections in Children; References; Encephalitis Diagnosis and Management in the Real World; References; Toxic Shock Syndrome -- Evolution of an Emerging Disease; References; Dissection of B-Cell Development to Unravel Defectsin Patients with a Primary Antibody Deficiency; References; Mumps is Back: Why is Mumps EradicationNot Working?; References; Neonatal Herpes Simplex Virus Infections: Where Are We Now; References; Rational Approach to Pediatric Antifungal Therapy; References; Antiviral Therapy of CMV Disease in Children , ReferencesInfectious Hazards from Pets and Domestic Animals; References; Novel Technology to Study Co-Evolution of Humans StaphylococcusINTtie; aureus: Consequences for Interpreting theINTtie; Biology of Colonisation and Infection; References; A Practical Approach to Eosinophilia in a Child Arriving orINTtie; Returning From the Tropics; References; Subject Index;

Additional Edition: ISBN 9781441971845

Additional Edition: Buchausg. u.d.T. ISBN 978-1-441-97184-5

Language: English

Subjects: Medicine

DOI: 10.1007/978-1-4419-7185-2

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Cover

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Format: XIII, 318 Seiten , Ill., graph. Darst. , 235 mm x 155 mm

ISBN: 9781441971845

Series Statement: Advances in experimental medicine and biology 659

Note: Text engl.

Language: English

Keywords: Kind ; Infektionskrankheit ; Kongress ; Oxford 〈2009〉 ; Kind ; Infektionskrankheit ; Antimikrobieller Wirkstoff ; Kongress ; Oxford 〈2009〉 ; Kongress

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Format: Online-Ressource (digital)

ISBN: 9780387798387 , 9780387798370

Series Statement: Advances in Experimental Medicine and Biology 634

Content: Course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections. This conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc.

Content: Covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections

Note: Description based upon print version of record , Hot Topics in Infection and Immunityin Children V; Acknowledgments; Contents; Contributors; Shiga-Toxin Producing Escherichia coli and the Hemolytic Uremic Syndrome: What Have We Learned in the Past 25 Years?; 1 Introduction; 2 History; 3 Epidemiology of E. coli O157:H7 Infections and HUS; 4 Clinical Course of E. coli Infection; 5 Pathophysiology of E. coli O157:H7 Infections; 6 Diagnostic Considerations for Pathogenic STEC; 7 Management of Patients with Confirmed or Suspected E. coli O157:H7 Infection; 8 HUS and the Course of E. coli O157:H7 Infections; 9 Pathophysiology of HUS , 10 ConclusionsReferences; Global Epidemiology of Pneumococcal Disease-New Prospects for Vaccine Control; 1 Overview of the Pneumococcus and Pneumococcal Disease; 2 Pneumonia; 3 Invasive Pneumococcal Disease; 4 Acute Otitis Media; 5 Pneumococcal Vaccines; 6 The Power of Pneumococcal Conjugate Vaccines I: Effect of PCV-7 on Rates of IPD in the US after Introduction in 2000; 7 The Power of Pneumococcal Conjugate Vaccines II: Effect of the 11-Valent PHiD-Conjugate Vaccine on AOM in a Phase III Efficacy Trial; 8 Pneumococcal Vaccines for Adults; 9 Conclusions; References , Current Concepts of the Pathogenesis of RSV Bronchiolitis1 Introduction; 2 Genetic Determinants of RSV Bronchiolitis and Post-bronchiolitis Wheeze; 3 Pre-existent Airway Morbidity; 4 Immature Immune Responses; 5 Immunopathogenesis; 6 Parallel Versus Serial Hypothesis; 7 Conclusions; References; How Can We Eradicate Pertussis; 1 Introduction; 2 Bordetella pertussis: The Organism and Its Pathogenesis; 3 Clinical Disease; 3.1 Pertussis in Young Infants; 3.2 Adults; 4 Laboratory Diagnosis of B. pertussis Infection; 4.1 Culture; 4.2 Direct Detection of B. pertussis , 4.3 Serologic Diagnosis of B. pertussis Infection5 Epidemiology; 5.1 Reported Pertussis; 5.2 Epidemiology of B. pertussis Infections; 6 Vaccines; 7 Conclusions; References; Recognition and Management of Encephalitis in Children; 1 Introduction; 2 History; 3 Etiology; 4 Postimmunization Neurological Disease; 5 Postinfectious Encephalitis; 6 Chronic Encephalitic or Encephalopathic Illnesses (Slow Infections); 7 Encephalitis Epidemiology; 8 Clinical Manifestations; 9 Differential Diagnosis; 10 Specific Diagnosis; 11 Treatment; 12 Prognosis; 13 Prevention; References , Microbiology and Management of Pleural Empyema1 Introduction; 2 Epidemiology and Aetiology; 2.1 Epidemiology; 2.2 Aetiology; 2.3 Risk Factors for Progression to Empyema; 3 Potential Reasons for Increasing Incidence of Empyema; 3.1 Serotype 1; 3.2 Sequence Types; 4 Management; 4.1 Prevention; 4.2 Drainage of Fluid; 5 Summary; References; Pneumococcal Conjugate Vaccines Probe Studies: The Solution Points to the Problem; 1 Observed Versus Expected Effect of a Vaccine - The Vaccine Probe Concept; 2 Vaccine Probe-Derived Insights into PCVs - Selected Examples , 2.1 Probe Studies in Pneumonia - the 'pneumonia detective'

Additional Edition: ISBN 9780387798370

Additional Edition: Buchausg. u.d.T. ISBN 978-0-387-79837-0

Language: English

DOI: 10.1007/978-0-387-79838-7

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Cover

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Format: Online-Ressource , v.: digital

Edition: Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web

ISBN: 9781441909817

Series Statement: Advances in Experimental Medicine and Biology 659

Content: Course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections. Each of the chapters in this book is based on a lecture given at the sixth "Infection and Immunity in Children" course, held at the end of June 2008 at Keble College, Oxford. Thus, it is the sixth book in a series that provides succinct and readable updates on just about every aspect of the discipline of Pediatric Infectious Diseases

Note: Includes bibliographical references and index , Preface; Acknowledgments; Contents; Contributors; Infections in the Immunocompromised; 1 Introduction; 2 Types of Immunodeficiency and Infection; 3 Site of Infection; 4 Respiratory Tract; 4.1 Pneumocystis jiroveci Pneumonia (PCP); 4.2 Viruses; 5 Gut; 5.1 Viruses; 5.2 Cryptosporidium; 5.3 Giardia; 6 Disseminated Infection; 6.1 Adenovirus; 6.2 Cytomegalovirus; 6.3 Epstein Barr Virus; 6.4 Human Herpes Virus 6; 6.5 Varicella Zoster Virus; 7 Fungal Infections; 7.1 Candidiasis; 7.2 Aspergillosis; 8 Central Venous Catheter Infections; 9 Febrile Neutropenia; 10 Conclusions; References , Host Biomarkers and Paediatric Infectious Diseases: From Molecular Profiles to Clinical Application1 Introduction; 2 Molecular Profiling: Current Techniques; 2.1 Genomics; 2.2 Transcriptomics; 2.3 Proteomics; 3 Clinical Applications in Pediatric Infectious Diseases; 3.1 What Has Been Studied up to now?; 3.2 Current and Potential Clinical Applications of ''''omic'' Technologies; 3.3 Future Perspectives for Biomarker Development; 4 Conclusions; References; The Epidemiology and Management of Non Typhoidal Salmonella Infections; 1 Introduction; 2 Seasonality of NTS infections , 3 Malaria, Anemia and NTS infection4 Malnutrition and NTS Infection; 5 HIV and NTS infection; 6 NTS Recurrence and Relapse; 7 Treatment of NTS Infections; References; Where Does Campylobacter Come From? A Molecular Odyssey; 1 Introduction; 2 Campylobacter Typing and Population Structure; 3 Epidemiology of Human Infection; 4 Host Association Studies of Chickens, Geese and Starlings; 5 Genetics of Host Association and Speciation; 6 Conclusion Impact of Molecular Epidemiology on Control of Human Infection; References; Why Are Some Babies Still Being Infected with HIV in the UK? , 1 Introduction2 Risk Factors for Transmission; 3 British HIV Association Guidelines 2008; 4 Transmission in the Era of HAART; 5 Clinical Scenario Emergency Management of a New Diagnosis of Maternal HIV at Delivery; 5.1 What Should be Done Before the Baby Is Born?; 5.2 Which Antiretrovirals Should be Started for the Baby?; 5.3 What Should be Done if the Mother is in Premature Labour?; 5.4 How Should the Infant be Tested for HIV?; 5.5 When Should Cotrimoxazole Prophylaxis be Started? , 5.6 What Is the Appropriate Management of a Mother Diagnosed with HIV Antenatally Who Has R efused Any Interventions?6 Conclusions; References; The Use and Abuse of Antibiotics and the Developmentof Antibiotic Resistance; 1 Introduction; 2 Antibiotic Resistance Is Inevitable; 3 Antibiotic Overuse and Misuse Is a Major Problem; 4 Antibiotic Use (and Abuse) Drives the Development of Resistance; 5 The Role of Antibiotic Use and Overuse in Facilitating the Emergence and Spread of Antibiotic-Resistant Pathogens Is Complex , 6 The Role of Antibiotic Use and Overuse in Facilitating the Emergence and Spread of Specific Antibiotic-Resistant Gram-Positive Pathogens in Pediatrics Pneumococci, Staphylococci and Enterococci , Electronic reproduction; Available via World Wide Web

Additional Edition: ISBN 9781441909800

Language: English

DOI: 10.1007/978-1-4419-0981-7

URL: Volltext  (lizenzpflichtig)

UID:

Format: Online-Ressource (XVII, 252 p. 32 illus., 15 illus. in color, digital)

ISBN: 9781461447269

Series Statement: Advances in Experimental Medicine and Biology

Content: Hot Topics in Infection and Immunity IX

Content: Hot Topics in Infection and Immunity IX

Note: Description based upon print version of record , Preface; Acknowledgments; Contents; Contributors; Chapter-1; Innovation for the 'Bottom 100 Million': Eliminating Neglected Tropical Diseases in the Americas; 1.1 Introduction: Poverty in the Americas; 1.2 Neglected Tropical Diseases in the Americas; 1.3 Adverse Effects on Maternal and Child Health, Poverty, and Conflict; 1.3.1 Maternal and Child Health; 1.3.2 Poverty and Conflict; 1.4 Eliminating NTDs in the Americas; 1.5 New 'Anti-Poverty Vaccines' will be Required; 1.6 Hookworm and Chagas Disease Vaccines; 1.7 Concluding Statement; References; Chapter-2 , Non-typhoidal Salmonella in Children: Microbiology, Epidemiology and Treatment2.1 Introduction; 2.2 Classification and Microbiology; 2.3 Epidemiology; 2.4 Pathogenesis; 2.5 Clinical Syndromes; 2.5.1 Acute Gastroenteritis; 2.5.2 Extra-intestinal Infection; 2.5.3 Non-infectious Sequelae; 2.5.4 Salmonella Carriage; 2.5.4.1 Convalescent Carriage; 2.5.4.2 Chronic Carriage; 2.6 Treatment; 2.6.1 NTS Gastroenteritis; 2.6.2 Convalescent NTS Carriage; 2.6.3 Chronic NTS carriage; 2.7 NTS and Pregnancy; 2.8 Antibiotic Resistance; 2.9 Infection Control; References; Chapter-3 , Invasive Fungal Infections in Patients with Chronic Granulomatous Disease3.1 Introduction; 3.2 Methods; 3.2.1 Search Strategy; 3.2.2 Criteria for Inclusion of Case Reports; 3.2.2.1 Criteria for Diagnosis of Chronic Granulomatous Disease; 3.2.2.2 Documentation of Infection; 3.2.2.3 Localisation of Infection; 3.3 Results; 3.4 Fungal Infections in CGD: by Clinical Manifestation; 3.4.1 Pneumonia; 3.4.2 Osteomyelitis; 3.4.3 Other Organ Involvement; 3.5 Fungal Infections in CGD: by Organism; 3.5.1 Aspergillus Fumigatus; 3.5.2 Aspergillus nidulans; 3.5.3 Other Aspergillus Species , 3.5.4 Non-Aspergillus Species3.5.4.1 Zygomycetes; 3.5.4.2 Candida Species; 3.5.4.3 Paecilomyces Species; 3.5.4.4 Scedosporium Species; 3.5.4.5 Trichosporon Species; 3.5.4.6 Miscellaneous; 3.6 Diagnosis; 3.6.1 Culture and Biopsy of Clinical Specimens; 3.6.2 Nucleic Acid Amplification, Antigens and Serology; 3.6.3 Radiologic Findings; 3.7 Treatment; 3.8 Clinical Outcome; 3.9 Conclusion; References; Chapter-4; Clostridium difficile in Children: A Review of Existing and Recently Uncovered Evidence; 4.1 Introduction , 4.2 The Complexity of Testing for C. difficile and Diagnosing C. difficile Infection4.3 Epidemiology of C. difficile in Children; 4.3.1 Clostridium difficile in Children in the Community; 4.3.1.1 Explanations for High Levels of Asymptomatic Colonisation; 4.3.2 Clostridium difficile in Hospitalised Children; 4.3.3 Clostridium difficile in Neonates; 4.4 Burden of CDAD in Children; 4.5 When to Consider CDAD and How to Test for it; 4.5.1 Children Without Co-morbidities; 4.5.2 Children with Co-morbidities; 4.6 Treatment Strategies; 4.7 Conclusions , 4.8 Search Strategy and Selection Criteria , Innovation for the ‘bottom 100 million’: eliminating neglected tropical diseases in the Americas -- Non-typhoidal Salmonella in children: microbiology, epidemiology and treatment -- Invasive fungal infections in patients with chronic granulomatous disease -- Clostridium difficile in children: a review of existing and recently uncovered evidence -- Diarrhea among children in developing countries -- Building confidence in vaccines -- Chronic recurrent multifocal osteomyelitis -- Recognition and treatment of chlamydial infections from birth to adolescence -- Treatment of resistant bacterial infections in children: thinking inside and outside the box -- An encephalitis primer -- The evidence behind prophylaxis and treatment of wound infection after surgery -- Infectious risks associated with biologics -- Cat scratch disease and other Bartonella infections -- When to think of Immunodeficiency? -- Mycetoma by Madurella mycetomatis: A completely neglected medico-social dilemma -- Elucidation and clinical role of emerging viral respiratory tract infections in children -- Urinary tract infections in children: microbial virulence versus host susceptibility -- Preventing urinary tract infections in early childhood -- How to get and get rid of gonorrhoea -- Management of severe malaria: results from recent trials. When to think of Immunodeficiency? -- Mycetoma by Madurella mycetomatis: A completely neglected medico-social dilemma -- Elucidation and clinical role of emerging viral respiratory tract infections in children -- Urinary tract infections in children: microbial virulence versus host susceptibility -- Preventing urinary tract infections in early childhood -- How to get and get rid of gonorrhoea -- Management of severe malaria: results from recent trials..

Additional Edition: ISBN 9781461447252

Additional Edition: Buchausg. u.d.T. ISBN 978-1-461-44725-2

Language: English

Subjects: Medicine

DOI: 10.1007/978-1-4614-4726-9

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Cover