Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Type of Medium
Language
Region
Subjects(RVK)
Access
  • 1
    UID:
    b3kat_BV025909246
    Format: XIV, 173 S. , Ill.
    ISBN: 3894122544
    Language: German
    Subjects: General works
    RVK:
    Keywords: Berliner Medizinhistorisches Museum ; Geschichte ; Ausstellungskatalog
    Author information: Dietel, Manfred 1949-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Online Resource
    Online Resource
    Berlin [u.a.] : Springer
    UID:
    b3kat_BV022867211
    Format: 1 Online-Ressource
    Edition: Online-Ausgabe Springer ebook collection. Medicine 2005-2008
    ISBN: 9783540460916
    Series Statement: Recent results in cancer research 176
    Additional Edition: Reproduktion von Targeted therapies in cancer 2007
    Additional Edition: Erscheint auch als Druck-Ausgabe, Hardcover ISBN 978-3-540-46090-9
    Additional Edition: Erscheint auch als Druck-Ausgabe, Hardcover ISBN 3-540-46090-X
    Language: English
    Keywords: Krebs ; Targeted drug delivery ; Aufsatzsammlung
    Author information: Dietel, Manfred 1949-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Online Resource
    Online Resource
    Berlin, Heidelberg : Springer Berlin Heidelberg
    UID:
    gbv_1649026080
    Format: Online-Ressource (XIV, 262 p. 57 illus, digital)
    ISBN: 9783540460916
    Series Statement: Recent Results in Cancer Research 176
    Content: From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body's non-neoplastic cells. Modern targeted therapies interact with defined molecules present on cancer cells, adding increased selectivity to their toxic effects. This book presents an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
    Content: From its introduction, oncological chemotherapy has been encumbered by its poor selectivity because most antiproliferative drugs are toxic not only to tumor cells but also to important populations of the bodys non-neoplastic cells. The resultant problems with unwanted side effects are compounded by difficulties in predicting the desired effectivity of chemotherapy in individual patients. This unsatisfactory situation has driven intensive research and development towards more specific and less toxic anticancer drugs over the last few decades. Several results of these efforts have reached the clinic and an even greater number are now in preclinical testing. Common to all these targeted therapies is their interaction with defined molecules present on cancer cells, which adds various degrees of increased selectivity to their toxic effects. As a consequence, detecting the target molecule on tumors before therapy holds great diagnostic potential for predicting the efficacy of the drug and personalizing therapy. This book aims to present translational scientists and clinicians with an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
    Note: Includes bibliographical references , Front Matter; Causality in Medicine; The Evolution of the Biomedical Paradigm in Oncology: Implications for Cancer Therapy; Anticancer Drug Discovery and Development; Beyond VEGF: Targeting Tumor Growth and Angiogenesis via Alternative Mechanisms; Aurora Kinases and Their Inhibitors: More Than One Target and One Drug; Signalling Pathways and Adhesion Molecules as Targets for Antiangiogenesis Therapy in Tumors; Developing T-Cell Therapies for Cancer in an Academic Setting; Anticancer Cell Therapy with TRAIL-Armed CD34+ Progenitor Cells , Linking Inflammation Reactions to Cancer: Novel Targets for Therapeutic StrategiesClinical Development of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors: What Lessons Have We Learned?; GIST As the Model of Paradigm Shift Towards Targeted Therapy of Solid Tumors: Update and Perspective on Trial Design; Monoclonal Antibodies in the Treatment of Malignant Lymphomas; Molecular Network Analysis using Reverse Phase Protein Microarrays for Patient Tailored Therapy; Back Matter
    Additional Edition: ISBN 9783540460909
    Additional Edition: Buchausg. u.d.T. Targeted therapies in cancer Berlin : Springer, 2007 ISBN 354046090X
    Additional Edition: ISBN 9783540460909
    Language: English
    Keywords: Krebs ; Targeted drug delivery ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Author information: Dietel, Manfred 1949-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    UID:
    gbv_1646654196
    Format: Online-Ressource (XV, 173 p. 16 illus, digital)
    ISBN: 9783540378617
    Series Statement: Ernst Schering Research Foundation Workshop Supplement 13 13
    Content: This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT. It focuses, however, on cancer risk and on risk of breast cancer in particular. The book advocates further epidemiological studies which incorporate pathobiological assessments.
    Content: Die Vor- und Nachteile der Hormonersatztherapie (HRT) werden von einer Expertengruppe hinsichtlich der epidemiologischen Beweislage diskutiert. Obwohl alle positiven und negativen Aspekte der HRT behandelt werden, liegt der Schwerpunkt der Diskussionen bei der Frage des Brustkrebsrisikos. Unter anderem wird gezeigt, dass die aus epidemiologischen Studien abgeleiteten Ergebnisse sich nicht mit den Wachstumseigenschaften dieser Tumoren decken so dass weiterführende Bevölkerungsuntersuchungen unter Einbeziehungen pathobiologischen Sachverstands notwendig erscheinen. This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of the current evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT, including issues concerning psychology, the cardiovascular system, bone structure, and carcinogenesis. It focuses, however, on cancer risk and on risk of breast cancer in particular. In doing so, it provides a detailed discussion of the pathobiological features of breast cancer, concluding that the evidence provided by epidemiological studies is in conflict with the biological growth features of breast cancer. It advocates further epidemiological studies which incorporate pathobiological assessments.
    Note: Includes bibliographical references , Proceedings of: "Women between biology and culture, a workshop held at Kloster Andechs from 27-29 August 2003, sponsored by Schering AG"--P. v
    Additional Edition: ISBN 9783540323419
    Additional Edition: Buchausg. u.d.T. Biologie und Epidemiologie der Hormonersatztherapie Berlin : Springer, 2006 ISBN 3540323414
    Additional Edition: ISBN 9783540323419
    Language: English
    Subjects: Medicine
    RVK:
    RVK:
    Keywords: Hormontherapie ; Hormontherapie ; Konferenzschrift
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Author information: Dietel, Manfred 1949-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    UID:
    b3kat_BV040606946
    Format: 1 Online-Ressource (XIV, 819 S.) , Ill.
    Edition: 3., neubearb. Aufl.
    ISBN: 9783642045646
    In: 6
    Additional Edition: Erscheint auch als Druckausgabe ISBN 978-3-642-04563-9
    Language: German
    Author information: Dietel, Manfred 1949-
    Author information: Remmele, Wolfgang 1930-2021
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    UID:
    b3kat_BV000235353
    Format: 167 S. , zahlr. Ill.
    ISBN: 343710778X
    Series Statement: Veröffentlichungen aus der Pathologie 119
    Note: PST: Functional morphology and pathology of parathyroid glands
    Language: German
    Subjects: Medicine
    RVK:
    Keywords: Epithelkörperchen ; Funktionsmorphologie ; Epithelkörperchenkrankheit ; Pathologie ; Epithelkörperchen
    Author information: Dietel, Manfred 1949-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    E-Resource
    E-Resource
    Berlin : Blackwell-Wiss.-Verl.
    UID:
    gbv_090054458
    Format: 1 CD-ROM , farb., mit Ton , Begleith. ([9] S.) , 12 cm
    ISBN: 3894122536
    Series Statement: Blackwell neue Medien
    Note: Systemvoraussetzungen: 486DX/66 (empfohlen Pentium); 4 MB Hauptspeicher (8 MB empfohlen), ca. 2 MB freier Festplattenspeicher; DOS ab 5.00 (empfohlen DOS 6.22), Windows 3.x oder 95, Video für Windows; Doublespeed-CD-ROM-Laufwerk (Quadspeed empfohlen); SVGA-Grafikkarte, 65000 Farben (Auflösung 800 x 600, 16-Bit-Soundkarte. - Titel auf dem Behältnis
    Language: Undetermined
    Keywords: Berliner Medizinhistorisches Museum ; Geschichte ; CD-ROM ; CD-ROM
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    UID:
    b3kat_BV046860735
    Format: 1 Online-Ressource
    Edition: 20. Auflage
    ISBN: 9783132435247 , 3132435244
    Uniform Title: Harrison's principles of internal medicine
    Note: In Zusammenarbeit mit der Charité , Erschienen: Band 1-4 und Register
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 3-13-243524-4
    Language: German
    Subjects: Medicine
    RVK:
    RVK:
    RVK:
    Keywords: Innere Medizin ; Lehrbuch
    Author information: Möckel, Martin
    Author information: Dietel, Manfred 1949-
    Author information: Suttorp, Norbert 1953-
    Author information: Siegmund, Britta 1971-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Image
    Image
    Berlin
    UID:
    b3kat_BV048475668
    Format: Foto (schwarz/weiß) , 8° / 16 x 11
    Additional Edition: Elektronische Reproduktion Berlin : Humboldt-Universität zu Berlin, Universitätsbibliothek, [zwischen 2000 und 2020]
    Language: Undetermined
    URL: Vollständiger Inhalt  (kostenfrei)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    UID:
    b3kat_BV025796714
    Format: Getr. Zählg. , Ill.
    Edition: 15. Aufl.
    Uniform Title: Harrison's principles of internal medicine
    In: 2
    Language: German
    Subjects: Medicine
    RVK:
    Author information: Braunwald, Eugene 1929-
    Author information: Dietel, Manfred 1949-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages