Format:
Online-Ressource (online resource)
ISBN:
9783540887195
Series Statement:
Advances in Anatomy, Embryology and Cell Biology 203
Content:
Adult neurogenesis has been questioned for many years. In the early 1900s, a dogma was established that denied new neuron formation in the adult brain. In the last century however, new discoveries have demonstrated the real existence of proliferation in the adult brain, and in the last decade, these studies led to the identification of neural stem cells in mammals. Adult neural stem cells are undifferentiated cells that are present in the adult brain and are capable of dividing and differentiating into glia and new neurons. Newly formed neurons terminally differentiate into mature neurons in the olfactory bulb and the dentate gyrus of the hippocampus. Since then, a number of new research lines have emerged whose common objective is the phenotypical and molecular characterization of brain stem cells. As a result, new therapies are successfully being applied to animal models for certain neurodegenerative diseases or stroke. At present, and in years to come, this finding extends to the adult human brain, and gives reason and hope to all the previous studies.
Note:
Includes bibliographical references and index
,
Preliminary; Historic Overview; Research Methodologies for Adult Neurogenesis; Neurogenesis in the Intact Adult Mammalian Central Nervous System; Oncogenesis vs. Neurogenesis; Adult Neurogenesis Under Pathological Stimulation: Ischemia; Therapeutic Potential of Neural Stem Cells; Concluding Remarks; Back matter
Additional Edition:
ISBN 9783540887188
Additional Edition:
Druckausg. Gil-Perotín, Sara Identification and characterization of nNeural progenitor cells in the adult mammalian brain Berlin : Springer, 2009 ISBN 9783540887188
Language:
English
Subjects:
Medicine
Keywords:
Säugetiere
;
Gehirn
;
Nervenstammzelle
;
Adulte Stammzelle
;
Säugetiere
;
Gehirn
;
Nervenstammzelle
;
Adulte Stammzelle
DOI:
10.1007/978-3-540-88719-5
URL:
Volltext
(lizenzpflichtig)
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