Kooperativer Bibliotheksverbund

Berlin Brandenburg

and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Language
Year
Person/Organisation
  • 1
    Article
    Article
    Language: French
    In: European Psychiatry, November 2014, Vol.29(8), pp.556-556
    Description: La présence d’hallucinations chez un patient souffrant d’un trouble de personnalité borderline (TPB), ou état limite, est une situation clinique courante qui peut mettre le psychiatre en difficulté. En effet, l’hallucination n’étant pas reconnue comme un symptôme appartenant au tableau clinique de ce trouble, sa présence pose la question du diagnostic différentiel avec la schizophrénie. Or l’histoire du concept de TPB est celle d’une progressive autonomisation vis-à-vis du groupe des psychoses, passant d’un trouble para-psychotique dans les années 1940 à une troisième voie structurelle, indépendante de la névrose et de la psychose, dans les années 1980. Dès lors, le constat clinique d’hallucinations dans le TPB vient rouvrir un débat de plus de 40ans sur la place de cette entité au sein de la nosologie psychiatrique. L’étude de la littérature scientifique récente sur ce sujet apporte des éclaircissements. Des hallucinations, essentiellement acoustico-verbales, sont retrouvées chez environ 30 % des patients souffrant de TPB. La plupart d’entre elles sont transitoires, déclenchées par des situations de stress, mais certaines durent plusieurs années. Sur le plan clinique, elles ont les mêmes caractéristiques que les hallucinations retrouvées dans la schizophrénie en termes de fréquence, de durée, de localisation spatiale, de niveau sonore et de contrôlabilité. Les seules différences sémiologiques sont un contenu plus négatifs (voix insultantes) et une détresse plus intense du sujet vis-à-vis de ces phénomènes hallucinatoires. Le terme de « pseudo-hallucinations », souvent utilisé à tord dans cette situation, devrait être abandonné car il disqualifie le vécu des patients et n’est pas cliniquement pertinent. En outre, l’attitude qui consiste à attribuer systématiquement les symptômes hallucinatoires du TPB à une comorbidité (prises de toxiques associées, troubles de l’humeur) n’est pas justifiée au regard de la littérature. Ainsi, dans l’état actuel des connaissances, les hallucinations peuvent être considérées comme un symptôme du TPB.
    Keywords: Trouble de Personnalité Borderline ; Etat Limite ; Hallucination ; Pseudo-Hallucination ; Medicine
    ISSN: 0924-9338
    E-ISSN: 1778-3585
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Language: English
    In: Journal of Business Venturing, May 2014, Vol.29(3), pp.392-404
    Description: Prior research is equivocal as to the performance implications of exploiting market-based opportunities by nonprofit organizations. We investigate an under-addressed measure of performance in this literature: organizational survival. Drawing upon resource dependence theory, we argue that performance is largely dependent upon the extent to which nonprofits focus on market-based opportunities. Through analysis of the population of Canadian charities, we find support for a U-shaped relationship indicating that low to moderate levels of market-based income decrease the likelihood of firm exit, whereas high levels increase this likelihood.
    Keywords: Social Entrepreneurship ; Resource Dependence Theory ; Nonprofit ; Opportunity Exploitation ; Business ; Economics
    ISSN: 0883-9026
    E-ISSN: 1873-2003
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Language: English
    In: Ecological Modelling, 2011, Vol.222(12), pp.1998-2010
    Description: ► The individual-based INDISIM-SOM model is far more sensitive to some parameters than to others. ► Key parameters for the evolution of C and N are microbial maintenance, energy, and death probability. ► The nitrification rate, in particular, appears highly affected by the death probability. ► The sensitivity analysis indicates what simplification of the model is possible. ► It also shows which parameters need to be evaluated with more accuracy than is currently achievable. The fate of soil carbon and nitrogen compounds in soils in response to climate change is currently the object of significant research. In particular, there is much interest in the development of a new generation of micro-scale models of soil ecosystems processes. Crucial to the elaboration of such models is the ability to describe the growth and metabolism of small numbers of individual microorganisms, distributed in a highly heterogeneous environment. In this context, the key objective of the research described in this article was to further develop an individual-based soil organic matter model, INDISIM-SOM, first proposed a few years ago, and to assess its performance with a broader experimental data set than previously considered. INDISIM-SOM models the dynamics and evolution of carbon and nitrogen associated with organic matter in soils. The model involves a number of state variables and parameters related to soil organic matter and microbial activity, including growth and decay of microbial biomass, temporal evolutions of easily hydrolysable N, mineral N in ammonium and nitrate, CO and O . The present article concentrates on the biotic components of the model. Simulation results demonstrate that the model can be calibrated to provide good fit to experimental data from laboratory incubation experiments performed on three different types of Mediterranean soils. In addition, analysis of the sensitivity toward its biotic parameters shows that the model is far more sensitive to some parameters, i.e., the microbial maintenance energy and the probability of random microbial death, than to others. These results suggest that, in the future, research should focus on securing better measurements of these parameters, on environmental determinants of the switch from active to dormant states, and on the causes of random cell death in soil ecosystems.
    Keywords: Individual-Based Model ; Soil Microbial Activity ; Soil Organic Matter ; C and N Mineralization ; Microbial Parameters ; Environmental Sciences ; Ecology
    ISSN: 0304-3800
    E-ISSN: 1872-7026
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Language: English
    In: European Journal of Inorganic Chemistry, 02 December 2013, Vol.2013(34), pp.5886-5895
    Description: The details of a synthesis method for biologically relevant hydrated calcium pyrophosphates (CPPs, CaPOHO) has been elucidated. Control of the pH (from 3.6 to 5.8) and the temperature (from 25 to 90 °C) during the synthesis enabled the preparation of four pure CPP phases within one hour without intermediates: monoclinic and triclinic calcium pyrophosphate dihydrate (CPPD, CaPO2HO), which are the two CPP phases detected in vivo in joints of arthritic patients, monoclinic tetrahydrate β (CPPT, CaPO4HO) and an amorphous phase (a‐CPP, CaPOHO). Four domains corresponding to the four different phases of hydrated calcium pyrophosphate were identified; a‐CPP was synthesised over a very wide pH and temperature range (up to 90 °C) within the domain of synthesis conditions explored, including physiological conditions (pH 7.4 and 37 °C). The as‐synthesised hydrated CPP phases were characterised by complementary techniques (powder X‐ray diffraction, FTIR and Raman spectroscopy, scanning electron microscopy and thermogravimetry) and chemical analyses. Rietveld refinement analyses of the as‐synthesised crystalline phases were performed, and there were significant differences between the m‐CPPD X‐ray diffraction pattern observed and previously published cell parameters. Vibrational spectroscopy allowed the crystalline and amorphous phases synthesised to be clearly distinguished and identified owing to the high flexibility of the pyrophosphate anion. Chemical analyses showed that the synthesis conditions used in this study did not allow significant hydrolysis of the pyrophosphate ions into phosphate ions, and the number of water molecules associated with each synthesised CPP phase was determined by thermogravimetric analysis. Different mechanisms of dehydration were also identified. The study of the formation of synthetic and well‐characterised hydrated calcium pyrophosphate phases and their availability in large amounts in vitro could allow progress to be made on the biological role of these phases and their possible transformations. This could also aid their detection in patients suffering from disease caused by calcium salt crystals and could clarify the mechanism by which CPP crystals form and evolve in vivo. Four forms of calcium pyrophosphate hydrate (CPP) have been synthesised and characterised by complementary techniques. There are no intermediates or other metal ions in the fast one‐step synthesis method, which is performed under controlled pH and temperature. This approach may help us to understand the formation of CPP crystals, which are involved in several types of arthritis.
    Keywords: Biological Calcification ; Physicochemical Characterization ; Calcium Pyrophosphate ; Synthetic Methods ; Hydrates ; Vibrational Spectroscopy
    ISSN: 1434-1948
    E-ISSN: 1099-0682
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Language: English
    In: Journal of Chromatography A, Oct 3, 2014, Vol.1362, p.43(6)
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.chroma.2014.08.055 Byline: K. Gras, J. Luong, R. Gras, H.J. Cortes, R.A. Shellie Abstract: acents Piston-cylinder extraction used for extracting furfurals from Manuka honey. acents Ultra-trace, practical GC analysis in less than 7min. acents No derivatisation required using a highly inert capillary column. acents 120x faster extraction compared to published result on SPME. acents 60x faster extraction compared to LLE with mechanical agitation. Author Affiliation: (a) University of Alberta, 116 Street and 85 Avenue, Edmonton, Alberta T6G 2R3, Canada (b) Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia (c) Dow Chemical Canada ULC, Highway 15, Fort Saskatchewan, Alberta T8L 2P4, Canada (d) HJ Cortes Consulting LLC, Midland, MI 48642, USA Article History: Received 8 April 2014; Revised 14 August 2014; Accepted 14 August 2014
    Keywords: Honey – Usage ; Honey – Analysis
    ISSN: 0021-9673
    Source: Cengage Learning, Inc.
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Language: English
    In: The Journal of Urology, September 2014, Vol.192(3), pp.850-855
    Description: Intraurethral injection of in vitro expanded autologous skeletal muscle derived cells is a new regenerative therapy for stress urinary incontinence. We examined the efficacy and safety of a simpler alternative strategy using freshly harvested, minced autologous skeletal muscle tissue with its inherent content of regenerative cells. A total of 20 and 15 women with uncomplicated and complicated stress urinary incontinence, respectively, received intraurethral injections of minced autologous skeletal muscle tissue and were followed for 1 year. Efficacy was assessed by the number of leakages in a 3-day diary and by ICIQ-SF scores. We calculated the rates of cure, defined as zero leaks in 3 days plus an ICIQ-SF score of 5 or less, and improvement, defined as simultaneous decreases in each outcome measure. Significant reductions were observed in each group in the mean number of leakages (p 〈0.01) and in ICIQ-SF scores (p 〈0.001). In the uncomplicated group cure and improvement were observed in 25% and 63% of patients, and in the complicated group they were noted in 7% and 57%, respectively. No voiding dysfunction developed and only minor adverse events were noted. Intraurethral injection of minced autologous muscle tissue is a simple surgical procedure that appears safe and moderately effective in women with uncomplicated stress urinary incontinence. It compares well to a more complicated regenerative strategy using in vitro expanded muscle derived cells.
    Keywords: Urethra ; Urinary Incontinence ; Stress ; Regeneration ; Quadriceps Muscle ; Stem Cells ; Medicine
    ISSN: 0022-5347
    E-ISSN: 1527-3792
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Language: English
    In: The Journal of Allergy and Clinical Immunology, May 2012, Vol.129(5), pp.1259-1266.e1
    Description: Structural changes to the airways are features of severe asthma. The bronchial epithelium facilitates this remodeling process. Learning about the changes that develop in the airway epithelium could improve our understanding of asthma pathogenesis and lead to new therapeutic approaches. We sought to determine the feasibility and relevance of air-liquid interface cultures of bronchial epithelium derived from endobronchial biopsy specimens of patients with different severities of asthma for studying the airway epithelium. Human bronchial epithelial cells derived from endobronchial biopsy specimens of patients with mild and severe asthma were maintained in culture for 21 days in an air-liquid interface to reproduce a fully differentiated airway epithelium. Initially, features of remodeling that included epithelial and subepithelial layers, as well as mucus production, were assessed in paraffin-embedded endobronchial biopsy specimens to evaluate morphologic characteristics of asthmatic patients’ epithelia. differentiated epithelia were then analyzed for morphology and function based on ultrastructural analysis, IL-8 release, lipoxin A generation, mucin production, and lipoxygenase gene expression. Morphologic and inflammatory imbalances initially observed in endobronchial biopsy specimens obtained from patients with severe or mild asthma persisted in the air-liquid interface reconstituted epithelium throughout the differentiation process to 21 days. Epithelium from patients with severe asthma produced greater levels of mucin, released more IL-8, and produced lower levels of lipoxin A than that from patients with mild asthma. Expression of 15-lipoxygenase 2 was increased in epithelium from patients with severe asthma, whereas expression levels of MUC5AC, MUC5B, 5-lipoxygenase, and 15-lipoxygeanse 1 were similar to those of patients with mild asthma. cultures of fully differentiated bronchial epithelium from endobronchial biopsy specimens maintain inherent phenotypic differences specifically related to the severity of asthma.
    Keywords: Epithelium ; Inflammation ; Resolution ; Asthma Severity ; Medicine
    ISSN: 0091-6749
    E-ISSN: 1097-6825
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Language: English
    In: International Journal of Food Microbiology, Nov 17, Vol.191, p.109(7)
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ijfoodmicro.2014.09.010 Byline: Lapo Mughini-Gras, Wilfrid van Pelt Abstract: Source attribution based on microbial subtyping is being performed in many countries to ascertain the main reservoirs of human salmonellosis and to assess the impact of food safety interventions. To account for differences in exposure, the amount of food available for consumption within a country is often included in Salmonella source attribution models along with the level of contamination. However, not all foods have an equal probability of serving as vehicles for salmonellas, as some foods are more likely to be consumed raw/undercooked than others, posing a relatively higher risk. Using Salmonella data from the Netherlands in 2001-2004, this study aims at elucidating whether and how the incorporation of food consumption data in two source attribution models - the (modified) Dutch and Hald models - affects their attributions. We also propose the incorporation of an additional parameter to weight the amount of food consumed by its likelihood to be consumed raw/undercooked by the population. Incorporating the amount of food consumed caused a drastic change in the ranking of the top reservoirs in the Dutch model, but not in the Hald model, which proved to be insensitive to additional weightings given that its source-dependent factor can account for both food consumption and the ability for foods to serve as vehicles for salmonellas. Compared to attributions without food consumption, the Dutch model including the amount of food consumed showed an increase in the percentage of cases attributable to pigs and a decrease in that of layers/eggs, which became the second reservoir, after pigs. This was not consistent with established knowledge indicating that layers/eggs, rather than pigs, were the main reservoir of human salmonellosis in that period. By incorporating the additional weight reflecting the likelihood for different foods to be consumed raw/undercooked, the attributions of the Dutch model were effectively adjusted, both in terms of ranking and percent contributions of the different reservoirs. We concluded that incorporating food consumption data in the Dutch model can significantly affect the results. Therefore, such data should be either excluded from this model or used together with an additional weight able to adjust the amount of food consumed by its likelihood to be consumed insufficiently cooked. This may help identifying the correct reservoirs, allowing attributions to more closely reflect the real chance for a given food to serve as a vehicle for salmonellas. Conversely, the Hald model works properly irrespective of inclusion of food consumption data. Article History: Received 16 December 2013; Revised 10 June 2014; Accepted 14 September 2014
    Keywords: Reservoirs (Water) – Analysis ; Food Consumption – Analysis ; Food Contamination – Analysis ; Salmonella – Analysis
    ISSN: 0168-1605
    Source: Cengage Learning, Inc.
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Language: English
    In: Journal of Chromatography A, 04 January 2013, Vol.1271(1), pp.185-191
    Description: ► Measurement of O , N , CO, CO and light hydrocarbons in one 12 min MDGC analysis. ► A practical, effective configuration employs of two 3-port planar microfluidic devices in series. ► PLOT capillary columns were employed for the separation of hydrocarbons. ► CO and CO were converted to methane using a post-column methanizer. ► CO, CO , and hydrocarbons were detected using FID. ► Flow modulated TCD was employed to measure O and N . An integrated gas chromatographic system has been successfully developed and implemented for the measurement of oxygen, nitrogen, carbon monoxide, carbon dioxide and light hydrocarbons in one single analysis. These analytes are frequently encountered in critical industrial petrochemical and chemical processes like catalytic cracking of naphtha or diesel fuel to lighter components used in gasoline. The system employs a practical, effective configuration consisting of two three-port planar microfluidic devices in series with each other, having built-in fluidic gates, and a mid-point pressure source. The use of planar microfluidic devices offers intangible advantages like in-oven switching with no mechanical moving parts, an inert sample flow path, and a leak-free operation even with multiple thermal cycles. In this way, necessary features such as selectivity enhancement, column isolation, column back-flushing, and improved system cleanliness were realized. Porous layer open tubular capillary columns were employed for the separation of hydrocarbons followed by flame ionization detection. After separation has occurred, carbon monoxide and carbon dioxide were converted to methane with the use of a nickel-based methanizer for detection with flame ionization. Flow modulated thermal conductivity detection was employed to measure oxygen and nitrogen. Separation of all the target analytes was achieved in one single analysis of less than 12 min. Reproducibility of retention times for all compounds were found to be less than 0.1% ( = 20). Reproducibility of area counts at two levels, namely 100 ppm and 1000 ppm over a period of two days were found to be less than 5.5% ( = 20). Oxygen and nitrogen were found to be linear over a range from 20 ppm to 10,000 ppm with correlation coefficients of at least 0.998 and detection limits of less than 10 ppm . Hydrocarbons of interest were found to be linear over a range from 200 ppb to 1000 ppm with correlation coefficients of greater than 0.999 and detection limits of less than 100 ppb .
    Keywords: Gas Chromatography ; Mdgc ; Planar Microfluidic Device ; Permanent Gases ; Light Hydrocarbons ; Chemistry
    ISSN: 0021-9673
    E-ISSN: 18733778
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Language: English
    In: Journal of Chromatography A, Oct 26, 2012, Vol.1261, p.136(6)
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.chroma.2012.06.087 Byline: J. Luong (a)(b), R. Gras (b), H.J. Cortes (a)(c), R.A. Shellie (a) Keywords: Ethylene oxide; Gas chromatography; Portable; Differential mobility detection; Air monitoring Abstract: a* Fast GC offers direct measurement of ppb level ethylene oxide in medical work places. a* Coupling a micromachined differential mobility detector improves analyte detectability. a* Method has no need for sample pre-treatment, pre-concentration or derivatization. a* Less than 5% RSD over a range from 5 to 500ppb (v/v) was obtained. Author Affiliation: (a) Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia (b) Dow Chemical Canada ULC, Highway 15, Fort Saskatchewan, Alberta T8L 2P4, Canada (c) HJ Cortes Consulting LLC, Midland, MI 48642, USA Article Note: (footnote) [star] Honouring Professor Dr. Milton Lee's 65th Birthday.
    Keywords: Silicon ; Ethylene Oxide ; Ethylene ; Gas Chromatography ; Heterocyclic Compounds
    ISSN: 0021-9673
    Source: Cengage Learning, Inc.
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages