Format:
Online-Ressource (1 online resource (642 p.))
,
digital, PDF file(s).
Edition:
Fourth edition
ISBN:
9780511581281
Content:
Improvements in the detection of fetal and neonatal brain injuries, advances in our understanding of the pathophysiology, cellular and molecular bases of encephalopathy, and new treatment options have all combined to produce significant changes in the management of neonatal brain disorders in the past few years. This new edition of Fetal and Neonatal Brain Injury brings the reader fully up to date with all advances in clinical management and outcome assessment. New material includes pregnancy-induced hypertension, HELLP syndrome and chronic hypertension, complications of multiple gestation, neurogenic disorders of the brain, neonatal stroke and much more. An expanded, highly illustrated chapter on structural and functional imaging of the fetal and neonatal brain is also included. An outstanding international team of highly experienced neonatologists and maternal-fetal medicine clinicians have produced a practical, authoritative clinical text that gives clear management advice to all clinicians involved in the treatment of these patients
Content:
Section 1. Epidemiology, pathophysiology, and pathogenesis of fetal and neonatal brain injury -- Neonatal encephalopathy: epidemiology and overview -- Mechanisms of neurodegeneration and therapeutics in animal models of neonatal hypoxic-ischemic encephalopathy -- Cellular and molecular biology of hypoxic-ischemic encephalopathy -- The pathogenesis of preterm brain injury -- Section 2. Pregnancy , labor, and delivery complications causing brain injury -- Prematurity and complication s of labor and delivery -- Risks and complications of multiple gestations -- Intrauterine growth restriction -- Maternal diseases that affect fetal development -- Obstetrical conditions and practices that affect the fetus and newborn -- Fetal and neonatal injury as a consequence of maternal substance abuse -- Hypertensive disorders of pregnancy -- Complications of labor and delivery -- Fetal response to asphyxia -- Antepartum evaluation of fetal well-being -- Intrapartum evaluation of the fetus -- Section 3. Clinical manifestations of hypoxic-ischemic encephalopathy -- The use of EEG in assessing acute and chronic brain damage in the newborn -- Neuroimaging in the evaluation of pattern and timing of fetal and neonatal brain abnormalities -- Light-based functional assessment of the brain -- Placental pathology and the etiology of fetal and neonatal brain injury -- Correlations of clinical, laboratory, imaging, and placental findings as to the timing of asphyxial events --
Content:
Section 4. Specific conditions associated with fetal and neonatal brain injury -- Congenital malformation s of the brain -- Neurogenetic disorders of the brain -- Hemorrhagic lesions of the central nervous system -- Neonatal stroke -- Hypoglycemia in the neonate -- Hyperbilirubinemia and kernicterus -- Polycythemia and fetal-maternal bleeding -- Hydrops fetalis -- Bacterial sepsis in the neonate -- Neonatal bacterial meningitis -- Neurological sequelae of congenital perinatal infection -- Perinatal human immunodeficiency virus infection -- Inborn errors of metabolism with features of hypoxic-ischemic encephalopathy -- Acidosis and alkalosis -- Meconium staining and the meconium aspiration syndrome -- Persistent pulmonary hypertension of the newborn -- Pediatric cardiac surgery: relevance to fetal and neonatal brain injury -- Section 5. Management of the depressed or neurologically dysfunctional neonate -- Neonatal resuscitation: immediate management -- Improving performance, reducing error, and minimizing risk in the delivery room -- Extended management following resuscitation -- Endogenous and exogenous neuroprotective mechanisms after hypoxic-ischemic injury -- Neonatal seizures: and expression of fetal or neonatal brain disorders -- Nutritional support of the asphyxiated infant -- Section 6. Assessing outcome of the brain-injured infant -- Early childhood neurodevelopmental outcome of preterm infants -- Cerebral palsy: advances in definition, classification, management, and outcome -- Long-term impact of neonatal events on speech, language development, and academic achievement -- Neurocognitive outcomes of term infants with perinatal asphyxia -- Appropriateness of intensive care application -- Medicolegal issues in perinatal brain injury
Note:
Title from publisher's bibliographic system (viewed on 05 Oct 2015)
Additional Edition:
ISBN 9780521888592
Additional Edition:
Druckausg. ISBN 978-052-188-859-2
Additional Edition:
Print version ISBN 9780521888592
Language:
English
DOI:
10.1017/CBO9780511581281
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