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  • 1
    Online Resource
    Online Resource
    Functional endocrinology of aging (1998)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069140
    Format: 1 Online-Ressource (VIII, 245 Seiten) , Diagramme
    ISBN: 9783318003314
    Series Statement: Interdisciplinary topics in gerontology Vol. 29
    Content: One of the most demanding aspects regarding the endocrinology of aging is to determine the extent to which hormones change with age, independent of age-related pathologies, and the clinical significance of these changes.The emphasis of the present volume is on function, as it is of particular interest to many nonspecialists under what circumstances endocrine therapy may be useful in the elderly. For this purpose, leading investigators in their respective fields review the most important hormonal systems affected by aging. Furthermore, to facilitate the utility of the reviews particularly for nonspecialists, the book emphasizes the critical analysis of specific issues: The extent to which the hormones considered really do change with age, especially in humans; the physiological significance and the causes of these changes; and the prospects for treatment.Additionally, this volume also includes reviews on subjects such as cytokines, the sympathetic nervous system and leptin, which have not been traditionally considered in reviews of endocrine systems. However, while the concept of hormone replacement in the elderly is promising, as the chapters in the present volume indicate, much more research is necessary to determine under what circumstances such therapy is appropriate rather than counterproductive
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-6726-8
    Language: English
    Subjects: Medicine
    RVK:
    YC 3200
    Keywords: Altern ; Endokrinopathie ; Endokrinopathie ; Alter ; Altern ; Endokrinologie ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-00331-4
    URL: Volltext
    URL: Volltext
    URL: Volltext  (Deutschlandweit zugänglich)
    URL: lizenzpflichtig
    Author information: Mobbs, Charles V.
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  • 2
    Online Resource
    Online Resource
    Dementia in clinical practice (2009)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069096
    Format: 1 Online-Ressource (X, 184 Seiten) , Illustrationen, Diagramme
    ISBN: 9783805590167
    Series Statement: Frontiers of neurology and neuroscience Vol. 24
    Content: This publication summarizes the most recent advances in neurobiology, diagnostic approaches and therapeutics of the major dementing illnesses such as Alzheimer’s disease, frontotemporal dementia, Lewy body disease, and vascular dementia. In a succinct, practical and comprehensive manner, it provides an updated view of the disorders likely to be encountered in a daily practice. Each section is focused on a major form of dementia and is organized following the same scheme reviewing the pathophysiology of the disease, its diagnostic challenges, its characteristic neuroimaging features, therapeutic interventions and patient management issues. Avoiding an overspecialized approach, the book bridges the gap between clinical practice, advanced imaging, recent therapeutics and basic sciences. Thus, it serves as an excellent guide for mental health professionals working in the field of dementia as well as primary care physicians and students
    Note: latest developments in diagnostic tools and imaging modalities, and therapeutic perspectives
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-9015-0
    Language: English
    Subjects: Medicine
    RVK:
    YH 5403
    Keywords: Demenz ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-8055-9016-7
    URL: Volltext
    URL: Volltext
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  • 3
    Online Resource
    Online Resource
    Mechanisms of dietary restriction in aging and disease (2007)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069233
    Format: 1 Online-Ressource (VIII, 198 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318013900
    Series Statement: Interdisciplinary topics in gerontology Vol. 35
    Content: Dietary restriction uniquely and robustly increases maximum lifespan and greatly reduces age-related diseases in many species, including yeast, flies, nematodes, and mammals. To study mechanisms mediating the protective effects of dietary restriction, the National Institute of Aging convened a program involving several leading gerontological laboratories. Results from many of these, as well as from other leading research institutions in the field, are presented in this book. The first three papers address general molecular mechanisms, derived in part from recent DNA microarray studies, that may mediate protective effects of dietary restriction. The subsequent articles examine specific model systems, including flies, nematodes and non-human primates, that have provided exciting new information about these mechanisms. Finally, mechanisms of dietary restriction mediating protective effects against cancer and neurological diseases are discussed. In addition to gerontologists and geriatricians, many other medical and nonmedical professionals in the field will find a great wealth of information on possible interventions that may ameliorate age-related diseases
    Note: dietary interventions to expand lifespan
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8170-7
    Language: English
    Subjects: Medicine
    RVK:
    YB 5020
    RVK:
    YT 7025
    Keywords: Altern ; Ernährung ; Hormesis ; Krankheit ; Hunger ; Nahrungsaufnahme ; Reduktion ; Alterskrankheit ; Diät ; Stoffwechselphysiologie ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-01390-0
    URL: Volltext
    URL: Volltext
    URL: lizenzpflichtig
    Author information: Mobbs, Charles V.
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  • 4
    Online Resource
    Online Resource
    Autonomic nervous system in old age (2004)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069036
    Format: 1 Online-Ressource (X, 137 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318010510
    Series Statement: Interdisciplinary topics in gerontology Vol. 33
    Content: With the remarkable increase in life expectancy in recent years, overall numbers of older individuals living with disability and functional dependence are likely to increase. Age-related changes and diseases involving the peripheral nervous system, particularly its autonomic elements, frequently play determining roles in late life health and functional independence. While basal sympathetic activity increases with normative aging, there is evidence of considerable dysregulation of the ability of the aging sympathetic nervous system to respond to a variety of challenges.In this book, investigators from several different disciplines discuss aging of the autonomic nervous system from a variety of perspectives. Given the fact that aging of the parasympathetic elements of the autonomic nervous system is not nearly as well understood as that of its sympathetic portions, greater emphasis has been placed on the latter.The topics of this volume provide an excellent overview addressing a number of clinically important questions by highlighting key clinical and basic research studies. This book should be of great interest for general physicians, specialists in geriatrics, and neurologists
    Note: bridging basic and clinical perspectives
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7685-7
    Language: English
    Subjects: Biology
    RVK:
    WW 3724
    Keywords: Alter ; Vegetatives Nervensystem ; Pathophysiologie ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-01051-0
    URL: Volltext
    URL: Volltext
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  • 5
    Online Resource
    Online Resource
    Management of aging : the University of Geneva experience (1999)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069227
    Format: 1 Online-Ressource (X, 267 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318004229
    Series Statement: Interdisciplinary topics in gerontology Vol. 30
    Content: One of the world’s major geriatric departments is housed in the Geneva University Hospital and has a 36-year-old history behind it. Some of its developments are set out in this book.Care programs such as geriatric concepts of care, community based support, convalescent beds, memory clinics, palliative medicine and care and practice of clinical ethics are discussed. Research has focussed on 15 years of comparative cross-sectional studies on aging in an urban and a rural area of Switzerland, prevalence of dementia in Geneva and Zurich, clinico-neuropathological correlation, fall prevention, hip fracture outcomes and the impact of nutrition on the recovery of hip fractures. Teaching activities include interactive pre-graduate teaching of geriatrics, patient-centered medicine, post ethics, teaching the teachers by the European Academy for Medicine of Aging. Networking by the Interfaculty Center of Gerontology, Swiss Foundation for Research on Healthy Aging and the WHO program on ‘Aging and Health’ are in progress.This book will be of interest to geriatricians, administrators, gerontological researchers and public health managers as it gives an insight into the setting up of a geriatric team and the implementation of geriatric programs
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-6860-9
    Language: English
    Subjects: Medicine
    RVK:
    YB 4800
    RVK:
    YB 5000
    Keywords: Alterskrankheit ; Geriatrie ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-00422-9
    URL: Volltext
    URL: Volltext
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  • 6
    Online Resource
    Online Resource
    Primate reproductive aging : cross-taxon perspectives (2008)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069351
    Format: 1 Online-Ressource (VI, 200 Seiten)
    ISBN: 9783805585231
    Series Statement: Interdisciplinary topics in gerontology Vol. 36
    Content: Due to the unusually long post-reproductive lifespan characteristic of human females, primate reproductive aging receives a great deal of attention. Promoting and supporting discussion on comparative analyses of aging among diverse primate species, including humans, this publication highlights current research on female primate reproductive aging from both institutional-based as well as field studies. The contributions highlight the complex interaction between somatic and reproductive senescence. The latter is broadly manifested along a cross-taxonomic evolutionary continuum, with humans at one end of the spectrum exhibiting the lengthiest post-reproductive lifespan.Primatologists, anthropologists, evolutionary biologists, animal behaviorists, endocrinologists, neuroscientists, and all scholars interested in aging and reproduction will find this book a valuable source of information. Considering the increasing number of geriatric primates held in captivity, it will also be helpful to animal care professionals, as it calls attention to the special care that primates may require in order to monitor, maintain and improve their health as they age
    Note: Includes bibliographical references and indexes
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8522-4
    Language: English
    Subjects: Biology
    RVK:
    WX 5038
    RVK:
    WX 7538
    Keywords: Primaten ; Altern ; Fortpflanzung ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-8055-8523-1
    URL: Volltext
    URL: Volltext
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  • 7
    Online Resource
    Online Resource
    Aging in nonhuman primates (2002)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069021
    Format: 1 Online-Ressource (VIII, 239 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318007770
    Series Statement: Interdisciplinary topics in gerontology Vol. 31
    Content: As the number of elderly people in human populations increases, the study of normal aging, age-related disorders, and enhanced longevity is taking on new urgency. Fundamental research will provide means of preventing and effectively treating the most debilitating and distressing aspects of advanced age. Considerations of aging in non-human life forms do not aim at life extension, but at an increasing appreciation for the biological role of the aging process in populations, in addition to developing a more comprehensive understanding of the mechanisms of aging.The present volume focuses on primate aging because human characteristics that evolved during their evolution are homologous with those of other primates. Therefore, the research on nonhuman primates will decidedly also contribute to our understanding of the process of human aging.The topics of this volume include brain aging and neurodegenerative diseases, social behavior, cognition and aging, skeletal aging in natural and captive conditions, and consequences of caloric restriction for life and health extension. The great variety of contributions aim at providing a survey of the relevant work in progress and increasing the understanding of normal and pathological aging and life-span enhancement in a variety of nonhuman primate species
    Note: for a better understanding of normal and pathological aging
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7312-2
    Language: English
    Subjects: Biology , Medicine
    RVK:
    WX 7539
    RVK:
    YB 4800
    Keywords: Primaten ; Altern ; Aufsatzsammlung ; Electronic books
    DOI: 10.1159/isbn.978-3-318-00777-0
    URL: Volltext
    URL: Volltext
    URL: Volltext
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  • 8
    Online Resource
    Online Resource
    Vision in Alzheimer's disease (2004)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069426
    Format: 1 Online-Ressource (XII, 331 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318010916
    Series Statement: Interdisciplinary topics in gerontology Vol. 34
    Content: Visual dysfunction is prevalent in Alzheimer’s disease and in related disorders such as posterior cortical atrophy and Down syndrome. The neuropathology of these disorders affects brain areas that process low-level vision as well as higher-order cognition and attention. This volume spans the range of topics on vision, from structure (retinal and cortical) to function (cortical activation) to behavior (perception, cognition, attention, hallucinations, and everyday activities). The chapters together indicate that lower-level visual deficits can contribute to, or masquerade as, higher-order cognitive impairments. As important, they suggest that vision-based interventions may improve patients’ lives. An emerging theme is that the study of variations in visual-system pathology, behavior, and genetic risk will likely provide insights into typical Alzheimer’s disease as well as related conditions. The visual disorders of Alzheimer’s original case and its cousins of the 21st century have much to teach us about the changing visual system in aging and age-related neurodegenerative disease.This book is essential reading for neurologists, neuropsychologists, ophthalmologists and optometrists, geriatricians and gerontologists, psychiatrists, occupational therapists and other health professionals who provide diagnosis and clinical care to individuals with Alzheimer’s disease and related disorders
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7757-1
    Language: English
    Subjects: Medicine
    RVK:
    YG 4075
    RVK:
    YO 4300
    Keywords: Alzheimerkrankheit ; Sehstörung ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-01091-6
    URL: Volltext
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  • 9
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    Online Resource
    Body composition and aging (2010)
    Basel : Karger
    Details
    UID:
    b3kat_BV040232266
    Format: 1 Online-Ressource (VI, 198 Seiten) , Illustrationen, Diagramme
    ISBN: 9783805595223
    Series Statement: Interdisciplinary topics in gerontology Vol. 37
    Content: Increased adiposity and decreased muscle mass contribute substantially to age-dependent disease and disability. In particular age-related increase in adiposity is quickly becoming a major threat to public health throughout the world. Although the hypothesis that age-related changes in body composition are due to lifestyle choices alone is well accepted, it is a vast oversimplification. This volume reflects the current knowledge in this rapidly developing field of research. The first part of the book discusses the extent to which increased adiposity contributes to age-related diseases and longevity. The 'obesity paradox', describing the protective role of overweight in decreasing mortality while increasing pathology, is covered in depth. Further chapters address specific aspects of the regulation of energy balance during aging, including the effects of changes in food intake. Finally the causes and consequences of loss of muscle mass and age-related osteoporosis are examined.A valuable help for physicians treating elderly patients, this book will also be of great interest to researchers studying energy balance, muscle physiology, bone disease, and other aspects of aging
    Note: Causes and consequences of increased adiposity and decreased muscle and bone mass
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-9521-6
    Language: English
    Subjects: Medicine
    RVK:
    YC 8125
    Keywords: Alter ; Körperliche Entwicklung ; Muskelatrophie ; Gewichtszunahme ; Aufsatzsammlung ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-8055-9522-3
    URL: Volltext
    URL: lizenzpflichtig
    URL: Volltext
    URL: Inhaltsverzeichnis
    Author information: Mobbs, Charles V.
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  • 10
    Book
    Book
    Management of aging : the university of Geneva experience (1999)
    Basel [u.a.] : Karger
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    UID:
    gbv_300131054
    Format: x, 267 p , Ill., graph. Darst , 25 cm
    ISBN: 3805568606
    Series Statement: Interdisciplinary topics in gerontology vol. 30
    Note: Literaturangaben
    Language: English
    Keywords: Alterskrankheit ; Alterskrankheit ; Geriatrie ; Aufsatzsammlung
    URL: Inhaltsverzeichnis
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