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  • 1
    UID:
    gbv_277669359
    Format: XVIII, 285 S
    ISBN: 0824814843 , 0824815017
    Series Statement: School of Hawaiian Asian & Pacific studies
    Uniform Title: Wo-de-sixiang-zizhuan 〈engl.〉
    Note: Aus dem Chines. übers
    Language: English
    Keywords: Biografie
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing, | Cham :Springer.
    UID:
    edocfu_BV046943793
    Format: 1 Online-Ressource (X, 352 p. 47 illus., 45 illus. in color).
    Edition: 1st ed. 2020
    ISBN: 978-3-030-47682-3
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47681-6
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47683-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47684-7
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 3
    UID:
    almahu_9948582029102882
    Format: X, 352 p. 47 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030476823
    Content: This book provides a detailed review of how oncology drug development has changed over the past decade, and serves as a comprehensive guide for the practicalities in setting up phase I trials. The book covers strategies to accelerate the development of novel antitumor compounds from the laboratory to clinical trials and beyond through the use of innovative mechanism-of-action pharmacodynamic biomarkers and pharmacokinetic studies. The reader will learn about all aspects of modern phase I trial designs, including the incorporation of precision medicine strategies, and approaches for rational patient allocation to novel anticancer therapies. Circulating biomarkers to assess mechanisms of response and resistance are changing the way we are assessing patient selection and are also covered in this book. The development of the different classes of antitumor agents are discussed, including chemotherapy, molecularly targeted agents, immunotherapies and also radiotherapy. The authors also discuss the lessons that the oncology field has learnt from the development of hematology-oncology drugs and how such strategies can be carried over into therapies for solid tumors. There is a dedicated chapter that covers the specialized statistical approaches necessary for phase I trial designs, including novel Bayesian strategies for dose escalation. This volume is designed to help clinicians better understand phase I clinical trials, but would also be of use to translational researchers (MDs and PhDs), and drug developers from academia and industry interested in cancer drug development. It could also be of use to phase I trial study coordinators, oncology nurses and advanced practice providers. Other health professionals interested in the treatment of cancer will also find this book of great value. .
    Note: Paradigm shift in oncology drug development -- Practicalities in setting up phase I trials -- Optimizing the preclinical development of antitumor agents for entry into phase I trials -- Considerations for the development of novel chemotherapies in phase I trials -- Considerations for the development of novel targeted agents in phase I trials -- Development of immunotherapeutic strategies in early phase clinical trials -- Assessment of radiotherapeutic strategies in phase I trials -- Development of combinatorial strategies in phase I trials -- Novel trial designs for early phase clinical trials -- Incorporating pharmacokinetic strategies for phase I trials -- Development of pharmacodynamic biomarkers for phase I trials -- Efficacy considerations for Phase I trials -- Incorporating precision medicine into Phase I clinical trials -- Molecular profiling of patients for clinical trials -- Incorporating circulating biomarkers into clinical trials -- Statistical considerations for early phase clinical trials -- Lessons from hematology for solid tumor drug development. .
    In: Springer Nature eBook
    Additional Edition: Printed edition: ISBN 9783030476816
    Additional Edition: Printed edition: ISBN 9783030476830
    Additional Edition: Printed edition: ISBN 9783030476847
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing, | Cham :Springer.
    UID:
    edoccha_BV046943793
    Format: 1 Online-Ressource (X, 352 p. 47 illus., 45 illus. in color).
    Edition: 1st ed. 2020
    ISBN: 978-3-030-47682-3
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47681-6
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47683-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47684-7
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 5
    UID:
    gbv_193408945
    Format: XIV, 292 S , graph. Darst
    ISBN: 1858983916
    Series Statement: New horizons in environmental economics
    Note: Conference proceedings. - Includes bibliographies and index , Enth. 16 Beitr.
    Language: English
    Subjects: Geography
    RVK:
    Keywords: Asien ; Energiewirtschaft ; Energiepolitik ; Kongress ; Taipeh ; Konferenzschrift ; Konferenzschrift
    Author information: Kleindorfer, Paul R. 1940-
    Author information: Kunreuther, Howard 1938-
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  • 6
    UID:
    almahu_BV007006262
    Format: XVIII, 285 S.
    ISBN: 0-8248-1484-3
    Series Statement: SHAPS library of translations
    Uniform Title: Wo-de-sixiang-zijuan
    Note: Aus d. Chines. übers.
    Language: English
    Subjects: Political Science
    RVK:
    RVK:
    Keywords: 1942- Yan, Jiaqi ; Autobiografie ; Biografie
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  • 7
    UID:
    almahu_BV044458595
    Format: 1 videodisc (89 min.) ; , Flyer mit Übersicht über die Kapitel und die Interviewpartner , 12 cm
    Edition: home use edition
    Content: Documents the representation and involvement of the Chinese in American cinema from the silent era to the 21st century
    Note: Originally produced in 2007. - Accompanying discussion guide entitled: Hollywood Chinese : study & discussion guide / written and edited by Arthur Dong ; contributing writers, Lorraine Dong, Gina Marchetti, Jun Xing. Harriman, NY : DeepFocus Productions, c2008 , Movie magic -- Cinematic memories -- Early Chinese images -- Chinatowns -- The curse of Quon Gwon -- Lotus blossom & Grandview films -- The good earth -- Anna May Wong -- Dragon seed -- Charlie Chan -- Fu Manchu -- Actor's dilemma -- World War II -- James Wong Howe -- Suzie Wong -- The last emperor -- Flower drum song -- Career paths -- Kung Fu -- James Hong -- Chan is missing -- The Joy Luck Club -- M. Butterfly -- The virility card -- Xiu Xiu -- Chinese from Asia -- Better luck tomorrow -- Progress and prospects , DVD-R, NTSC; 16 x 9 widescreen; Dolby digital 5.1 surround or stereo sound , This disc is a recorded DVD and may not play on all DVD equipment
    Language: English
    Keywords: DVD-Video ; Feature films / United States ; Documentary films ; Feature films ; Nonfiction films
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  • 8
    UID:
    edocfu_9959229998202883
    Format: 1 online resource (xx, 1143 pages) : , illustrations (some color), maps
    ISBN: 981-4579-44-0
    Series Statement: Gale eBooks
    Content: China is emerging as one of the economic giants of the world, and is gaining international influence and global leadership that commensurate with its rise. China's performance will have far-reaching consequences on whether the economic awakening of the country, which began more than three decades ago, can become a good model to be emulated by other developing economies. This book is a collection of policy papers and data-sets for the 34 Greater China economies. With a comprehensive approach to competitiveness, the research by Asia Competitiveness Institute (ACI) at Lee Kuan Yew School of Publi
    Note: "Lee Kuan Yew School of Public Policy, Asia Competitiveness Institute." , Contents; Foreword; Preface; Acknowledgements; List of Economies; List of Abbreviations; Directory of Tables and Figures; Chapter 1 Annual Analysis of Competitiveness, Simulation Studies and Development Perspective for 34 Greater China Economies: An Overview; 1. BACKGROUND; 2. METHODOLOGY; 2.1 Four Environments and Eleven Sub-Environments; 2.2 Indicators; 2.3 Data Sources; 2.4 Standardised Score; 2.5 What-if Competitiveness Simulation Analysis; 3. RESEARCH FINDINGS; 3.1 Overall Competitiveness Ranking and Score for 2010: Quantitative Spread , 3.2 Overall Competitiveness Ranking and Score: Evolution over Time (2000-2010)3.3 Overall Competitiveness Ranking and Score for 2010: Geographical Distribution; 3.4 Four Environment Ranking and Score 2010 - Geographical Distribution; 3.5 What-if Competitiveness Simulation Analysis Results; 4. CHINA TOWARDS BECOMING THE WORLD'S LARGEST ECONOMY: VALUABLE LESSONS, IMPACT AND IMPLICATIONS TO DEVELOPMENT STRATEGIES, GLOBAL TRADE AND REGION ECONOMIC INTEGRATION; 4.1 Becoming the World's Largest Economy: Is China Prepared and Ready for It? , 4.2 Valuable Lessons on Asia Pacific Growth Strategies, Free Trade Agreements and Regional Economic Integration4.3 China-ASEAN Connectivity, Comprehensive Strategic Partnerships and Regional Infrastructure Investments; 5. STRESSES, BOTTLENECKS AND CHALLENGES RESULTED FROM DECADES OF ECONOMIC EXPANSION: THE WAY FORWARD; References , Review 1: Working Hard to Further Improve Competitiveness by Dr Tang Min, Counsellor, the State Council & Executive Vice-Chairperson, YouChange China Social Entrepreneur Foundation & Council Member, China Council for International Cooperation on Environment and Development, People's Republic of ChinaReview 2: A Review of the "Annual Analysis of Competitiveness, Simulation Studies and Development Perspective for 34 Greater China Economies: 2000-2010" by Dr Zhang Jun, Director, China Center for Economic Studies & Vice Dean, Fudan Development Institute, University, People's Republic of China , GENERAL REVIEWSPECIFIC OPINIONS AND SUGGESTIONS; Review 3: Factor Endowments, Regional Transitions and Competitiveness Cycles - A review of the "Annual Analysis of Competitiveness, Simulation Studies and Development Perspective for 34 Greater China Economies: 2000-2010" by Dr Wei Houkai, Deputy Director, Institute for Urban and Environmental Studies, Chinese Academy of Social Sciences (CASS), People's Republic of China; 1. INTRODUCTION; 2. UNIQUE ASPECTS OF ACI'S COMPETITIVENESS REPORT; 3. FACTOR ENDOWMENTS, ECONOMIC SCALE AND REGIONAL COMPETITIVENESS , 4. THE HYPOTHESIS OF REGIONAL TRANSITION AND COMPETITIVENESS CYCLES , English
    Additional Edition: ISBN 1-322-06375-3
    Additional Edition: ISBN 981-4579-42-4
    Language: English
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  • 9
    UID:
    edocfu_9960739028002883
    Format: 1 online resource
    ISBN: 9780824847296
    Series Statement: SHAPS Library of Translations
    Note: In English.
    Language: English
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