Kooperativer Bibliotheksverbund

UID:

Format: XVIII, 285 S

ISBN: 0824814843 , 0824815017

Series Statement: School of Hawaiian Asian & Pacific studies

Uniform Title: Wo-de-sixiang-zizhuan 〈engl.〉

Note: Aus dem Chines. übers

Language: English

Keywords: Biografie

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Format: 1 Online-Ressource (X, 352 p. 47 illus., 45 illus. in color).

Edition: 1st ed. 2020

ISBN: 978-3-030-47682-3

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47681-6

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47683-0

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47684-7

Language: English

DOI: 10.1007/978-3-030-47682-3

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: X, 352 p. 47 illus., 45 illus. in color. , online resource.

Edition: 1st ed. 2020.

ISBN: 9783030476823

Content: This book provides a detailed review of how oncology drug development has changed over the past decade, and serves as a comprehensive guide for the practicalities in setting up phase I trials. The book covers strategies to accelerate the development of novel antitumor compounds from the laboratory to clinical trials and beyond through the use of innovative mechanism-of-action pharmacodynamic biomarkers and pharmacokinetic studies. The reader will learn about all aspects of modern phase I trial designs, including the incorporation of precision medicine strategies, and approaches for rational patient allocation to novel anticancer therapies. Circulating biomarkers to assess mechanisms of response and resistance are changing the way we are assessing patient selection and are also covered in this book. The development of the different classes of antitumor agents are discussed, including chemotherapy, molecularly targeted agents, immunotherapies and also radiotherapy. The authors also discuss the lessons that the oncology field has learnt from the development of hematology-oncology drugs and how such strategies can be carried over into therapies for solid tumors. There is a dedicated chapter that covers the specialized statistical approaches necessary for phase I trial designs, including novel Bayesian strategies for dose escalation. This volume is designed to help clinicians better understand phase I clinical trials, but would also be of use to translational researchers (MDs and PhDs), and drug developers from academia and industry interested in cancer drug development. It could also be of use to phase I trial study coordinators, oncology nurses and advanced practice providers. Other health professionals interested in the treatment of cancer will also find this book of great value. .

Note: Paradigm shift in oncology drug development -- Practicalities in setting up phase I trials -- Optimizing the preclinical development of antitumor agents for entry into phase I trials -- Considerations for the development of novel chemotherapies in phase I trials -- Considerations for the development of novel targeted agents in phase I trials -- Development of immunotherapeutic strategies in early phase clinical trials -- Assessment of radiotherapeutic strategies in phase I trials -- Development of combinatorial strategies in phase I trials -- Novel trial designs for early phase clinical trials -- Incorporating pharmacokinetic strategies for phase I trials -- Development of pharmacodynamic biomarkers for phase I trials -- Efficacy considerations for Phase I trials -- Incorporating precision medicine into Phase I clinical trials -- Molecular profiling of patients for clinical trials -- Incorporating circulating biomarkers into clinical trials -- Statistical considerations for early phase clinical trials -- Lessons from hematology for solid tumor drug development. .

In: Springer Nature eBook

Additional Edition: Printed edition: ISBN 9783030476816

Additional Edition: Printed edition: ISBN 9783030476830

Additional Edition: Printed edition: ISBN 9783030476847

Language: English

DOI: 10.1007/978-3-030-47682-3

URL: https://doi.org/10.1007/978-3-030-47682-3

UID:

Format: 1 Online-Ressource (X, 352 p. 47 illus., 45 illus. in color).

Edition: 1st ed. 2020

ISBN: 978-3-030-47682-3

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47681-6

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47683-0

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-47684-7

Language: English

DOI: 10.1007/978-3-030-47682-3

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: XIV, 292 S , graph. Darst

ISBN: 1858983916

Series Statement: New horizons in environmental economics

Note: Conference proceedings. - Includes bibliographies and index , Enth. 16 Beitr.

Language: English

Subjects: Geography

Keywords: Asien ; Energiewirtschaft ; Energiepolitik ; Kongress ; Taipeh ; Konferenzschrift ; Konferenzschrift

Author information: Kleindorfer, Paul R. 1940-

Author information: Kunreuther, Howard 1938-

UID:

Format: XVIII, 285 S.

ISBN: 0-8248-1484-3

Series Statement: SHAPS library of translations

Uniform Title: Wo-de-sixiang-zijuan

Note: Aus d. Chines. übers.

Language: English

Subjects: Political Science

Keywords: 1942- Yan, Jiaqi ; Autobiografie ; Biografie

UID:

Format: 1 videodisc (89 min.) ; , Flyer mit Übersicht über die Kapitel und die Interviewpartner , 12 cm

Edition: home use edition

Content: Documents the representation and involvement of the Chinese in American cinema from the silent era to the 21st century

Note: Originally produced in 2007. - Accompanying discussion guide entitled: Hollywood Chinese : study & discussion guide / written and edited by Arthur Dong ; contributing writers, Lorraine Dong, Gina Marchetti, Jun Xing. Harriman, NY : DeepFocus Productions, c2008 , Movie magic -- Cinematic memories -- Early Chinese images -- Chinatowns -- The curse of Quon Gwon -- Lotus blossom & Grandview films -- The good earth -- Anna May Wong -- Dragon seed -- Charlie Chan -- Fu Manchu -- Actor's dilemma -- World War II -- James Wong Howe -- Suzie Wong -- The last emperor -- Flower drum song -- Career paths -- Kung Fu -- James Hong -- Chan is missing -- The Joy Luck Club -- M. Butterfly -- The virility card -- Xiu Xiu -- Chinese from Asia -- Better luck tomorrow -- Progress and prospects , DVD-R, NTSC; 16 x 9 widescreen; Dolby digital 5.1 surround or stereo sound , This disc is a recorded DVD and may not play on all DVD equipment

Language: English

Keywords: DVD-Video ; Feature films / United States ; Documentary films ; Feature films ; Nonfiction films

URL: Connect to reviews of this title online

UID:

Format: 1 online resource (xx, 1143 pages) : , illustrations (some color), maps

ISBN: 981-4579-44-0

Series Statement: Gale eBooks

Content: China is emerging as one of the economic giants of the world, and is gaining international influence and global leadership that commensurate with its rise. China's performance will have far-reaching consequences on whether the economic awakening of the country, which began more than three decades ago, can become a good model to be emulated by other developing economies. This book is a collection of policy papers and data-sets for the 34 Greater China economies. With a comprehensive approach to competitiveness, the research by Asia Competitiveness Institute (ACI) at Lee Kuan Yew School of Publi

Note: "Lee Kuan Yew School of Public Policy, Asia Competitiveness Institute." , Contents; Foreword; Preface; Acknowledgements; List of Economies; List of Abbreviations; Directory of Tables and Figures; Chapter 1 Annual Analysis of Competitiveness, Simulation Studies and Development Perspective for 34 Greater China Economies: An Overview; 1. BACKGROUND; 2. METHODOLOGY; 2.1 Four Environments and Eleven Sub-Environments; 2.2 Indicators; 2.3 Data Sources; 2.4 Standardised Score; 2.5 What-if Competitiveness Simulation Analysis; 3. RESEARCH FINDINGS; 3.1 Overall Competitiveness Ranking and Score for 2010: Quantitative Spread , 3.2 Overall Competitiveness Ranking and Score: Evolution over Time (2000-2010)3.3 Overall Competitiveness Ranking and Score for 2010: Geographical Distribution; 3.4 Four Environment Ranking and Score 2010 - Geographical Distribution; 3.5 What-if Competitiveness Simulation Analysis Results; 4. CHINA TOWARDS BECOMING THE WORLD'S LARGEST ECONOMY: VALUABLE LESSONS, IMPACT AND IMPLICATIONS TO DEVELOPMENT STRATEGIES, GLOBAL TRADE AND REGION ECONOMIC INTEGRATION; 4.1 Becoming the World's Largest Economy: Is China Prepared and Ready for It? , 4.2 Valuable Lessons on Asia Pacific Growth Strategies, Free Trade Agreements and Regional Economic Integration4.3 China-ASEAN Connectivity, Comprehensive Strategic Partnerships and Regional Infrastructure Investments; 5. STRESSES, BOTTLENECKS AND CHALLENGES RESULTED FROM DECADES OF ECONOMIC EXPANSION: THE WAY FORWARD; References , Review 1: Working Hard to Further Improve Competitiveness by Dr Tang Min, Counsellor, the State Council & Executive Vice-Chairperson, YouChange China Social Entrepreneur Foundation & Council Member, China Council for International Cooperation on Environment and Development, People's Republic of ChinaReview 2: A Review of the "Annual Analysis of Competitiveness, Simulation Studies and Development Perspective for 34 Greater China Economies: 2000-2010" by Dr Zhang Jun, Director, China Center for Economic Studies & Vice Dean, Fudan Development Institute, University, People's Republic of China , GENERAL REVIEWSPECIFIC OPINIONS AND SUGGESTIONS; Review 3: Factor Endowments, Regional Transitions and Competitiveness Cycles - A review of the "Annual Analysis of Competitiveness, Simulation Studies and Development Perspective for 34 Greater China Economies: 2000-2010" by Dr Wei Houkai, Deputy Director, Institute for Urban and Environmental Studies, Chinese Academy of Social Sciences (CASS), People's Republic of China; 1. INTRODUCTION; 2. UNIQUE ASPECTS OF ACI'S COMPETITIVENESS REPORT; 3. FACTOR ENDOWMENTS, ECONOMIC SCALE AND REGIONAL COMPETITIVENESS , 4. THE HYPOTHESIS OF REGIONAL TRANSITION AND COMPETITIVENESS CYCLES , English

Additional Edition: ISBN 1-322-06375-3

Additional Edition: ISBN 981-4579-42-4

Language: English

UID:

Format: 1 online resource

ISBN: 9780824847296

Series Statement: SHAPS Library of Translations

Note: In English.

Language: English

URL: https://www.degruyter.com/isbn/9780824847296