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  • 1
    Language: English
    In: The American Journal of Surgery, December 2012, Vol.204(6), pp.988-995
    Description: Soft tissue infections have historically been diagnosed on the basis of clinical signs and symptoms. A trend toward the increased use of computed tomographic (CT) imaging in their evaluation has been noted. A retrospective review was performed of soft tissue infection admissions in 2003 and 2004 and in 2009 and 2010. Intracavitary abscesses (eg, intra-abdominal, pelvic) that would not be evident on physical examination were excluded. Demographic and outcome variables, number of CT scans by body region, and total effective radiation dose were recorded. Radiation exposure was stratified into low, moderate, high, and very high categories. There was a significant increase in the number of patients receiving ≥1 CT scan for initial diagnosis, from 36.7% in the early cohort to 50% in the later cohort ( 〈 .001). The mean cumulative effective dose increased from 5.46 to 7.82 mSv ( = .007). Greater proportions of patients fell into the moderate (32.9% vs 24.5%) and high (6.8% vs 10.6%) radiation exposure categories. CT scans are increasingly used in the evaluation of soft tissue infections, with resultant increase in radiation exposure.
    Keywords: Soft Tissue Infections ; Radiation Exposure ; Effective Dose ; Computed Tomographic Scan
    ISSN: 0002-9610
    E-ISSN: 1879-1883
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  • 2
    Language: English
    In: Journal of Theoretical Biology, 14 December 2018, Vol.459, pp.90-102
    Description: Many environmental factors, such as annual precipitation, temperature variations, and the embedded stochasticity of natural systems, affect resource availability from one region to the next, such that animal survival and reproduction rates differ by region. For species exhibiting phenotypic plasticity, embedding phenotypes in a model of population dynamics becomes important, as region–driven plastic responses play a significant role when estimating parameters values. In this paper, we discuss how to include observable characteristics and climate patterns in estimates of reproduction rates of whitetail deer ( ). Using many studies already available in the literature, we establish a strong correlation between reproduction rate and both body weight and USDA plant hardiness zone. We demonstrate the accuracy of the estimated whitetail deer fecundity rates for various geographical regions in North America and show that Bergmann’s rule is necessary to maintain similar biological fitness between various spatial distributions of deer populations. We demonstrate that the standard deviation of the weight distribution has almost no effect on reproduction rate estimates for adult deer populations. However, statistical analysis reveals sensitivity of fawn reproduction rates to environmental stochasticity. We incorporate the reproduction function in a stage– and gender–based model and prove the existence of a stable solution. Finally, we demonstrate a possible application of the model using harvested deer weights, without collecting reproduction data directly.
    Keywords: Phenotypes ; Fecundity ; Eviscerated Weight ; Usda Hardiness Zone ; Deer Management ; Biology
    ISSN: 0022-5193
    E-ISSN: 1095-8541
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  • 3
    Language: English
    In: Archives of otolaryngology--head & neck surgery, November 2011, Vol.137(11), pp.1141-5
    Description: To analyze the possible correlation between the location of the primary tumor within the thyroid gland and the patterns of central vs lateral compartment lymph node metastasis. Retrospective analysis of papillary thyroid carcinoma (PTC) treated in an academic university setting from July 1, 2004, through August 31, 2010. Head and neck oncology clinic. Those receiving surgical therapy for PTC at the University of Utah. Tumor characteristics of patients with central vs lateral nodal metastatic disease in PTC. Two hundred one patients with PTC met inclusion criteria. There were 136 females (67.7%), and the mean age was 44.8 years. Histologic subtypes included 68 follicular variants of PTC, 111 conventional variants of PTC, and 22 patients with both follicular and conventional PTC variants. Metastatic nodal disease was confirmed histologically in 81 patients (40.3%): 42 with central nodal disease only (20.9%), 10 with lateral disease only (5.0%), and 29 with both central and lateral nodal disease (14.4%). Positive lateral compartment nodal metastasis correlated with distant metastases (P 〈 .01), extrathyroid extension (P 〈 .05), histologic subtype (conventional PTC greater than follicular variant PTC) (P 〈 .05), and tumor location within the thyroid lobe (P 〈 .01). Tumors involving the superior aspect of the thyroid lobe were more likely to be associated with metastasis to the lateral cervical lymph nodes (P 〈 .01), and 76.9% of patients with lateral cervical lymph node disease had involvement of the superior aspect of the lobe. Thyroid microcarcinomas were not associated with lateral cervical compartments in this study. The intrathyroidal location of PTC predicts the pattern of nodal spread. Therefore, patients with PTC involving the superior aspect of the lobe should undergo specific imaging evaluation of the lateral neck compartments to determine the need for lateral compartment neck dissection.
    Keywords: Carcinoma, Papillary -- Secondary ; Lymph Nodes -- Pathology ; Thyroid Neoplasms -- Pathology
    ISSN: 08864470
    E-ISSN: 1538-361X
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  • 4
    Language: English
    In: Thyroid : official journal of the American Thyroid Association, May 2011, Vol.21(5), pp.551-3
    Description: Substernal goiters are frequently associated with compressive symptoms. Compression of the trachea and esophagus are common, whereas thoracic duct compression is a rare occurrence. We report a rare case of a 72-year-old woman with thoracic duct compression by a large substernal goiter that presented with shortness of breath. After undergoing thoracentesis multiple times, the patient was treated with thyroidectomy. Transcervical thyroidectomy was performed without sternotomy. This led to resolution of her symptoms. Confirmation of chylothorax resolution was obtained with postoperative computed tomography of the chest. Chylothorax is a rare sequela of substernal goiters. It can be managed with thyroidectomy. Sternotomy was avoided in this case.
    Keywords: Chylothorax -- Complications ; Goiter, Substernal -- Complications ; Thyroidectomy -- Methods
    ISSN: 10507256
    E-ISSN: 1557-9077
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  • 5
    Language: English
    In: Journal of Infectious Diseases, Sept 1, 2013, Vol.208(5), p.720(8)
    Keywords: Haemophilus Influenzae -- Genetic Aspects ; Haemophilus Influenzae -- Research ; Genetic Variation -- Research
    ISSN: 0022-1899
    Source: Cengage Learning, Inc.
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  • 6
    Language: English
    In: Desalination and Water Treatment, 01/2013, Vol.51(4-6), pp.759-765
    Description: Construction of mega RO facilities (train capacity of 5,000 m 3 /day and larger) faces many challenges including cost-effective utilization of energy recovery devices (ERDs) and high-pressure pumps. Recently, mega system owners and integrators have selected turbochargers with single train capacity exceeding 20,000 m 3 of daily permeate output. This study analyzes several ERD configurations in single- and two-stage arrays with a capacity of 20,000 m 3 /day. In particular, two-stage (brine staged) configurations are extensively explored to establish the limits of specific energy consumption (SEC) reduction under realistic operating scenarios. Commercially available membrane projection software was used to develop a mathematical model of membrane array performance including the effects of feed total dissolved solids, temperature, age, and polarization. Software was developed to evaluate tens of thousands of membrane configurations along with hundreds of operating conditions to identify ERD applications and array configurations that provide the lowest SECs. A figure of merit was defined to ensure unbiased comparison of results. The findings showed that two-stage arrays provide an SEC reduction of about 3% with optimal recovery around 47% relative to single-stage arrays with the same number of membrane elements. Perhaps the most interesting finding from a practical perspective is that turbochargers in an optimized two-stage array have an SEC about the same as isobaric chambers in optimized single-stage arrays. Article ahead-of-print.
    Keywords: Swro ; Erd ; Motor Assisted Turbocharger ; Energy Consumption ; Train Configuration;
    ISSN: 1944-3994
    E-ISSN: 1944-3986
    Source: Informa - Taylor & Francis (via CrossRef)
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  • 7
    Language: English
    In: Proceedings of the International Astronomical Union, 04/2017, Vol.12(S330), pp.222-224
    Description: I summarize two recent projects involving the Gaia-TGAS data. Firstly, I discuss a detection of a lack of disc stars in the Solar neighbourhood with velocities close to zero angular momentum. We use predictions of this effect to make a measurement of the Solar rotation velocity around the Galactic centre,...
    Keywords: Solar Rotation ; Galactic Rotation ; Angular Momentum ; Solar Rotation ; Galactic Structure ; Angular Velocity ; Angular Momentum ; Stellar Rotation ; Computer Simulation ; Solar Neighborhood ; Milky Way ; Velocity ; Milky Way Galaxy ; Galaxy: Kinematics and Dynamics ; Galaxy: Fundamental Parameters;
    ISSN: 1743-9213
    E-ISSN: 1743-9221
    Source: CrossRef
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  • 8
    Language: English
    In: Desalination and Water Treatment, 07/2011, Vol.31(1-3), pp.88-94
    Description: The high pressure hydraulic energy management integration (HP-HEMI) energy recovery device (ERD) centralizes brine hydraulic energy recovery, feed pressure and flow control and brine pressure and flow control into one compact and fully integrated unit. The objective is to dispense with feed pressure control valves (i.e. elimination of throttling losses) as well as a variable frequency drive (VFD) on the high pressure feed pump (HPP) resulting in the twin benefits of a substantial reduction in energy consumption and capital costs. This paper reports on test results of a production HP-HEMI coping with recoveries and pressures that accurately simulate an SWRO system dealing with typical feed temperature and membrane fouling variations. The paper further reports on development of a PLC control scheme that regulates feed flow and brine flow via adjustment of the HP-HEMI control features to meet a wide variety of membrane operating conditions. The paper also outlines future research concerning mitigation of equipment failure and further enhancements of system control.
    Keywords: Engineering;
    ISSN: 1944-3994
    E-ISSN: 1944-3986
    Source: CrossRef
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  • 9
    Language: English
    In: Journal of Neurological Surgery Reports, 2014, Vol.75(01)
    In: Journal of Neurological Surgery Reports, 2014, Vol.75(01), pp.e5-e10
    Description: Objectives Describe the use of the supraclavicular artery flap for reconstruction of lateral skull and scalp defects. Discuss advantages and potential limitations of the supraclavicular artery flap. Design Case series. Setting Tertiary care academic medical center. Participants Patients undergoing lateral scalp and skull base resections. Main Outcome Measures Effectiveness in reconstructing lateral skull base defects and complications. Results All three patients reconstructed with the supraclavicular artery flap had excellent reconstructive outcomes. There were no flap losses, either complete or partial. There were no major complications, but one patient had a significant donor site dehiscence requiring local wound care. Referred sensation to the shoulder was alleviated by division of the sensory innervations into the flap. Conclusions The supraclavicular artery flap is an excellent option for lateral skull and scalp defects, and donor site morbidity is limited. It should be considered as an alternative to free tissue transfer.
    Keywords: Supraclavicular flap ; Lateral skull base ; Reconstruction ; Regional flap
    ISSN: 2193-6358
    E-ISSN: 2193-6366
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  • 10
    In: PLoS ONE, 2018, Vol.13(5)
    Description: Nontypeable Haemophilus influenzae (NT Hi ) has been shown to form biofilms, comprised of extracellular DNA (eDNA), in the middle ear and bronchus during clinical infections. Studies in our laboratory have shown that NT Hi possesses a homolog of Staphylococcus aureus thermonuclease (staphylococcal thermonuclease), NT Hi nuclease (NT Hi Nuc, HI_1296). This enzyme had similar size, heat stability, and divalent cation requirements to those of the staphylococcal homolog as determined by light scattering and circular dichroism spectroscopy. Small angle X-ray scattering (SAXS) analysis suggested an overall shape and substrate-binding site comparable to those of staphylococcal nuclease. However, NT Hi Nuc was approximately 25-fold more active in fluorescence resonance energy transfer (FRET) activity assay than staphylococcal thermonuclease. Homology modeling implicates shorter NT Hi Nuc loops near the active site for this enhanced activity.
    Keywords: Research Article ; Biology And Life Sciences ; Biology And Life Sciences ; Medicine And Health Sciences ; Biology And Life Sciences ; Biology And Life Sciences ; Biology And Life Sciences ; Research And Analysis Methods ; Physical Sciences ; Biology And Life Sciences ; Biology And Life Sciences ; Biology And Life Sciences ; Biology And Life Sciences ; Medicine And Health Sciences ; Physical Sciences ; Physical Sciences ; Physical Sciences
    E-ISSN: 1932-6203
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