Format:
1 online resource (256 pages)
ISBN:
9781493918300
Series Statement:
Molecular Pathology Library v.8
Content:
This book serves as a comprehensive guide to the rapidly evolving field of molecular neuropathology of nervous system tumors, as well as the underlying biology and emerging molecular targeted therapies. Special emphasis is given to already established and emerging molecular diagnostic tests in neuropathology, as well as molecular targeted therapies. The book is organized by clinico-pathologic disease entities, and each chapter is written by a team of experts in their field. Molecular Pathology of Nervous System Tumors is of great value and utility for physicians and scientists involved with or interested in the up-to-date diagnosis and treatment of patients with brain tumors.
Content:
Intro -- Foreword -- Preface -- Contents -- Contributors -- 1: Hereditary Predisposition to Primary CNS Tumors -- Syndromes Associated with Glioma -- Neurofibromatosis Type I (NF1, von Recklinghausen's Disease) -- Molecular Pathogenesis -- Gliomas -- Clinical Implications -- Molecular Targeted Therapies -- Li-Fraumeni Syndrome -- Molecular Pathogenesis -- Clinical Implications -- Constitutional Mismatch Repair Deficiency Syndrome -- Molecular Pathogenesis -- Brain Tumors -- Clinical Implications -- Melanoma Astrocytoma Syndrome -- Syndromes Associated with Medulloblastoma -- Gorlin Syndrome (Basal Cell Nevus Syndrome) -- Molecular Pathogenesis -- Medulloblastoma -- Meningioma -- Clinical Implications -- Brain Tumor-Polyposis Syndrome 2 (BTPS 2 or Turcot Type 2 -- Familial Adenomatosis Coli) -- Molecular Pathogenesis -- Clinical Implications -- Fanconi Anemia Cancer Predisposition Disorders -- Molecular Pathogenesis -- Clinical Implications -- Meningioma -- Tumor Specific Syndromes -- Subependymal Giant Cell Astrocytoma -- Molecular Pathogenesis -- Clinical Implications -- Atypical Teratoid Rhabdoid Tumor -- Molecular Pathogenesis -- Clinical Implications -- Hemangioblastoma -- Molecular Pathogenesis -- CNS Hemangioblastomas -- Clinical Implications -- Development of New Medications -- Cerebellar Dysplastic Gangliocytoma (Lhermitte-Duclos Disease) -- Brain Tumors -- Molecular Pathogenesis -- Clinical Implications -- Vestibular Schwannomas (Acoustic Neuromas) -- Molecular Pathogenesis -- Intracranial Tumors -- Spinal Tumors -- Clinical Implications -- Implications of Molecular Tumor Testing on Genetic Counseling -- Summary -- References -- 2: Brain Tumor Stem Cells -- Cancer Stem Cell Definition -- Brain Tumor Initiation -- Neurogenesis in the Adult Brain -- Gliomagenesis -- Identification of Brain Tumor Stem Cells.
Note:
Description based on publisher supplied metadata and other sources
Additional Edition:
9781493918294
Additional Edition:
Erscheint auch als Druck-Ausgabe 9781493918294
Language:
English
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