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  • 1
    Language: German
    Description: Mit einem Geleitwort von Prof. Dr. Dr. h. c. mult. Christian Homburg.
    Keywords: Economics/Management Science ; Marketing ; Business
    ISBN: 9783834923363
    ISBN: 3834923362
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  • 2
    Language: English
    In: Journal of Business Research, June 2014, Vol.67(6), pp.1114-1122
    Description: Marketing managers commonly employ complex price plans. Surprisingly, limited and conflicting evidence reports how customers perceive and react to complex prices. This study examines perceptions about price complexity and shows that customers tend to prefer simple prices. Two experimental studies show that perceived price complexity negatively affects customer perceptions of price fairness and influences product choice because customers negatively evaluate the transparency of the firm's pricing practices and infer higher total prices. Customers comparing alternate offerings may therefore prefer simple over complex prices, even when the latter are less expensive. Study results suggest limiting price plan variations positively affects customer inferences about transparency and fairness, and thus customer choice.
    Keywords: Behavioral Pricing ; Price Complexity ; Price Transparency ; Price Fairness ; Simplicity Bias ; Business ; Economics
    ISSN: 0148-2963
    E-ISSN: 1873-7978
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  • 3
    Language: English
    In: Addictive Behaviors, October 2013, Vol.38(10), pp.2586-2588
    Description: Social norms have been consistently shown to influence alcohol use among college students. Much of the research in this area is focused on mostly White samples. This study sought to expand our understanding of social norms theory by examining perceptions of normative alcohol use among Black students and determining the impact of the race of reference group members on personal alcohol use. Participants ( = 130; 73.8% female) completed an online questionnaire. Results of repeated measures of analysis of variance indicated that participants perceived all referent groups (i.e., White, same race, typical student) as drinking significantly more than they did. Results of hierarchical regression analysis indicated that perceptions of typical student drinking significantly predicted personal alcohol use. Implications for practice and research are discussed.
    Keywords: Social Norms ; Alcohol Use ; College Student Drinking ; African American ; Black ; Social Welfare & Social Work
    ISSN: 0306-4603
    E-ISSN: 1873-6327
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  • 4
    In: AIDS, 2010, Vol.24(2), pp.327-328
    Description: In adults, HIV-1 seroreversion following antiretroviral therapy is rare and has been reported only in patients who were treated shortly after primary HIV-1 infection [1-3]. In HIV-1 infected infants, seroreversion after suppression of viral replication appears to be more frequent than in adults [4,5]. However, these infants were asymptomatic or mildly symptomatic and were treated in the first 3 months of life. After this time period, especially when the clinical picture of AIDS has been developed, seroreversion following antiretroviral therapy has not been reported yet. Here, we report the unusual case of seroreversion following antiretroviral therapy in a child vertically infected with HIV initially presenting with AIDS defining conditions.
    Keywords: Human Immunodeficiency Virus 1 ; Human Immunodeficiency Virus 1 ; Antiretroviral Therapy ; Acquired Immune Deficiency Syndrome ; Infants ; Replication ; Infection ; Immunodeficiency ; Antiretroviral Therapy ; Acquired Immune Deficiency Syndrome ; Infants ; Replication ; Infection ; Immunodeficiency ; Microorganisms & Parasites ; AIDS and HIV;
    ISSN: 0269-9370
    E-ISSN: 14735571
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  • 5
    In: The Journal of Virology, 2010, Vol. 84(12), p.5909
    Description: The rat parvovirus H-1 (H-1PV) attracts high attention as an anticancer agent, because it is not pathogenic for humans and has oncotropic and oncosuppressive properties. The viral nonstructural NS1 protein is thought to mediate H-1PV cytotoxicity, but its exact contribution to this process remains undefined. In this study, we analyzed the effects of the H-1PV NS1 protein on human cell proliferation and cell viability. We show that NS1 expression is sufficient to induce the accumulation of cells in G(2) phase, apoptosis via caspase 9 and 3 activation, and cell lysis. Similarly, cells infected with wild-type H-1PV arrest in G(2) phase and undergo apoptosis. Furthermore, we also show that both expression of NS1 and H-1PV infection lead to higher levels of intracellular reactive oxygen species (ROS), associated with DNA double-strand breaks. Antioxidant treatment reduces ROS levels and strongly decreases NS1- and virus-induced DNA damage, cell cycle arrest, and apoptosis, indicating that NS1-induced ROS are important mediators of H-1PV cytotoxicity.
    Keywords: Biology;
    ISSN: 0022-538X
    ISSN: 0022538X
    E-ISSN: 10985514
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  • 6
    In: Homburg, Christian und Totzek, Dirk und Krämer, Melanie (2014) How price complexity takes its toll: The neglected role of a simplicity bias and fairness in price evaluations. Journal of Business Research : JBR 67 6 1114-1122 [Zeitschriftenartikel]
    Description: Marketing managers commonly employ complex price plans. Surprisingly, limited and conflicting evidence reports how customers perceive and react to complex prices. This study examines perceptions about price complexity and shows that customers tend to prefer simple prices. Two experimental studies show that perceived price complexity negatively affects customer perceptions of price fairness and influences product choice because customers negatively evaluate the transparency of the firm's pricing practices and infer higher total prices. Customers comparing alternate offerings may therefore prefer simple over complex prices, even when the latter are less expensive. Study results suggest limiting price plan variations positively affects customer inferences about transparency and fairness, and thus customer choice.
    Keywords: 650 Management
    Source: Mannheim University Library
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  • 7
    Language: English
    In: Memory, 02 January 2014, Vol.22(1), pp.51-64
    Description: Merely contemplating one's death improves retention for entirely unrelated material learned subsequently. This "dying to remember" effect seems conceptually related to the survival processing effect, whereby processing items for their relevance to being stranded in the grasslands leads to recall...
    Keywords: Adaptive Memory ; Survival Processing ; Mortality Salience ; Dying to Remember ; Item-Specific ; Death Processing ; Psychology
    ISSN: 0965-8211
    E-ISSN: 1464-0686
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  • 8
    Language: English
    In: Biosensors and Bioelectronics, 2009, Vol.24(6), pp.1563-1568
    Description: The proof of principle of a reusable surface plasmon resonance (SPR)-based immunosensor for the monitoring of isoproturon (IPU), a selective and systemic herbicide, is presented. The detecting rat monoclonal anti-isoproturon antibody (mAb IOC 7E1) was reversibly immobilized through the use of a capture mouse anti-rat (κ-chain) monoclonal antibody (mAb TIB 172), which was covalently immobilized on the sensor chip surface. Such strategy features a controlled binding of the captured detecting antibody as well as facilitates the surface regeneration. The capture of the anti-IPU mAb by the antibody (TIB 172) coated sensor surface could be carried out up to 120 times (immobilization/regeneration cycles) without any evidence of activity loss. With a high test midpoint and a low associated SPR signal, the direct detection format was shown to be unsuitable for the routine analysis of isoproturon. However, the limit of detection (LOD) could be easily enhanced by using a strategy based on a surface competition assay, which improved all immunosensor parameters. Moreover, the sensitivity and working range of the indirect format were found to be dependent on the surface density of the anti-IPU mAb IOC 7E1. As expected for competitive formats, the lowest surface coverage (0.5 ng/mm ) allowed a lower detection of the herbicide isoproturon with a calculated LOD of 0.1 μg/l, an IC (50% inhibition) of 5.3 ± 0.6 μg/l, and a working range (20–80% inhibition) of 1.3–16.3 μg/l.
    Keywords: Surface Plasmon Resonance ; Immunosensor ; Isoproturon ; Capture Antibody ; Competitive Format ; Engineering ; Biology
    ISSN: 0956-5663
    E-ISSN: 1873-4235
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  • 9
    Language: English
    In: Memory, 02 January 2014, Vol.22(1), pp.36-50
    Description: Processing items for their relevance to survival improves recall for those items relative to numerous other deep processing encoding techniques. Perhaps related, placing individuals in a mortality salient state has also been shown to enhance...
    Keywords: Adaptive Memory ; Survival Processing ; Mortality Salience ; Item-Specific ; Cumulative Recall ; Psychology
    ISSN: 0965-8211
    E-ISSN: 1464-0686
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  • 10
    Language: English
    In: Inorganic chemistry, 06 August 2012, Vol.51(15), pp.8385-93
    Description: Black single crystals of the new dodecahalogenotrimetallate In(4)Ti(3)Br(12) were obtained by reacting InBr(3) with Ti-wire at 450 °C in a silica tube sealed under vacuum. In(4)Ti(3)Br(12) (Pearson symbol hR57, space group R3m, Z = 3, a = 7.3992(8) Å, c = 36.673(6) Å, 643 refl., 25 param., R(1)(F) = 0.025; wR(2)(F(2)) = 0.046) is a defect variant of a 12 L-perovskite. In(+) cations are 12-fold coordinated in two different ways: In1 as an anticuboctahedron and In2 as a cuboctahedron. In both cases the 5s(2) configuration results in 3 short, 6 medium, and 3 long In-Br distances which might be explained as lone pair effect or second order Jahn-Teller instability. Furthermore there are isolated linear trimers [Ti(3)Br(12)](4-) consisting of facesharing octahedra similar to [Ru(3)Cl(12)](4-). The [Ti(3)Br(12)](4-)-unit has to be described as a mixed-valent d(1)-d(2)-d(1) system. According to magnetic measurements, the Ti-atoms in In(4)Ti(3)Br(12) show strong antiferromagnetic interactions (Θ = -1216(6) K) which might be addressed as weak Ti(3+)-Ti(2+)-Ti(3+) bonds. For comparison, single crystals of K(3)Ti(2)X(9) (X = Cl, Br) were synthesized and their structures refined. The rotation of the Ti(2)X(9)(3-) dimers reduced the symmetry of the well-known Cs(3)Cr(2)Cl(9) type from P6(3)/mmc to P6(3)/m and resulted in the formation of merohedral twins. According to the unit cell volumes In(+) is smaller than K(+) in all cases.
    Keywords: Antiferromagnetism -- Analysis ; Metal Bonding -- Analysis ; Molecular Rotation -- Analysis ; Molecular Structure -- Analysis ; Titanium Compounds -- Chemical Properties ; Titanium Compounds -- Magnetic Properties ; Titanium Compounds -- Structure;
    ISSN: 00201669
    E-ISSN: 1520-510X
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