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  • 1
    Conference Proceeding
    Conference Proceeding
    Editorial Universitat Politècnica de València
    Language: English
    Description: [EN] Since October 2015 the government of the federal republic of Germany is developing a national dialogue on the future development of the National Strategy for Sustainability made in 2016. The development is marked by the Agenda 2030 which was adopted by the United Nations for Sustainable Development in 2015. Therefore, the major global challenges must be addressed by all means of sustainable development, trying to reduce hunger, poverty, lack of education as well as environmental and climate issues. All these objectives are addressed to all member states of the European Union, which raises the question: How can the new global sustainability goals be implemented at the national level? What has to happen in Germany to further promote sustainable development? The article focuses on the objective of sustainable urban development in Germany, exemplifying the case oft he oldtown of Berlin-Spandau, a istrict of the City of Berlin. Firstly, the priority objectives will be demonstrated, later on implementation strategies will be explained. The practical application will be demonstrated after a short, theoretical introduction. Thie project itself was realized under the supervision of the author at the University of Hamburg and demonstrates strategies of greening that not only improve the climate of the city but also reinforce social cohesion through its planning measures.
    Keywords: Urban Greening ; Urban Planning ; Berlin ; Sustainability ; Germany
    Source: Universitat Politècnica de València
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  • 2
    Language: English
    In: Soil Biology and Biochemistry, September 2018, Vol.124, pp.168-178
    Description: Substantial amounts of organic matter are mobilized from upper soil layers during extreme precipitation events. This results in considerable fluxes of carbon from plant-associated topsoil to deeper mineral soil and to groundwater. Microbes constitute an important part of this mobile organic matter (MOM) pool. Previous work has shown that specific bacteria associated with the rhizosphere of decaying maize roots were selectively transported with seepage water upon snowmelt in winter. However, effective mechanisms of mobilization and also possible distinctions to microbial transport for living root systems remain poorly understood. In the present study, bacteria in seepage water were sampled from lysimeters at an experimental maize field after extreme rain events in summer. We show that a distinctive subset of rhizoplane-associated bacterial populations was mobilized after summer rain, especially including abundant members of the , representing a microbial conduit for fresh plant-derived carbon inputs into deeper soil layers. Marked distinctions of seepage communities were not observed between lysimeters with a different relative contribution of preferential vs. matrix flow. Time-resolved analyses of seepage water during an artificial rain event revealed temporal patterns in the mobilization of certain lineages, with members of the , , and preferentially mobilized in early and late seepage fractions, and members of the candidate phyla and mobilized mostly in intermediate fractions. While average bacterial cell counts were at ∼10  ml in seepage water, the recovery of amended fluorescently labeled cells of was low (0.2–0.6%) over seepage events. Still, mobilized bacteria clearly have the potential to influence bacterial activities and communities in subsoils. These findings demonstrate that dynamic hydraulic events must be considered for a better understanding of the connectivities between microbial populations and communities in soil, as well as of the links between distinct carbon pools over depth.
    Keywords: Natural Rain ; Artificial Rain ; Preferential Flow ; Seepage Water ; Soil Bacterial Communities ; Agriculture ; Chemistry
    ISSN: 0038-0717
    E-ISSN: 1879-3428
    Source: ScienceDirect Journals (Elsevier)
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  • 3
    In: it - Information Technology, 01/28/2014, Vol.56(5)
    Description: Complex network analysis is concerned with identifying statistically significant patterns in large and complex networks. A complex network is an abstract model of a complex system; it represents a well-chosen set of entities as nodes and one or more types of relationships between them as edges. Methods from complex network analysis have been used to identify small molecules called miRNAs that are able to stop breast cancer [13], to understand possible privacy breaches [9], or to analyze how humans solve complex problems [10]. As many areas in our globalized world tend to get more interconnected, the methods from complex network analysis became more important: for complex systems with an underlying network structure, the framework of complex network analysis provides the potential to identify central nodes, to describe deviating substructures, and to reveal the interaction between structure and function of complex networks. Based on this potential impact of network analysis on many fields of society, my work concentrates on understanding when to use which kind of network measure to analyze complex networks and where their limits are, a field I call network analysis literacy. This question can easily be generalized to data analysis literacy which can be even more generalized to the influence of our modern IT-systems on the individual, on organizations, and on society at large, which culminates in a new field of study called socioinformatics.
    Keywords: Datenanalyse ; Komplexes System ; Brustkrebs ; Konzentrat ; Engineering;
    ISSN: 1611-2776
    E-ISSN: 2196-7032
    Source: Walter de Gruyter (via CrossRef)
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  • 4
    Language: English
    In: Geoderma, 01 September 2018, Vol.325, pp.37-48
    Description: Organic particles including microorganisms are a significant fraction of the mobile organic matter (MOM) pool that contributes to initial pedogenesis. Still, the dynamics and the interplay of the multitude of processes that control the mobilization, transport, and retention of MOM are vastly unclear. We studied this interplay using an ‘artificial soil’ as model for a young, unstructured soil with defined initial composition employing a novel two-layer column experiment. The upstream layer was composed of a mixture of well-defined mineral phases, a sterile organic matter source and a diverse, natural microbial inoculant mimicking an organic-rich topsoil. The downstream layer, mimicking the subsoil, was composed of the mineral phases, only. Columns were run under water-unsaturated flow conditions with multiple flow interruptions to reflect natural flow regimes and to detect possible non-equilibrium processes. Pore system changes caused by flow were inspected by scanning electron microscopy and computed micro-tomography. MOM-related physicochemical effluent parameters and bacterial community diversity and abundance were assessed by molecular analysis of the effluent and the solid phase obtained after the long-term irrigation experiment (75 d). Tomographic data showed homogeneous packing of the fine-grained media (sandy loam). During flow, the initially single-grain structured artificial soil showed no connected macropores. In total, 6% of the initial top layer organic matter was mobile. The release and transport of particulate (1.2%) and dissolved organic matter (4.8%) including bacteria were controlled by non-equilibrium conditions. Bacterial cells were released and selectively transported to downstream layer resulting in a depth-dependent and selective establishment of bacterial communities in the previously sterile artificial soil. This study underlines the importance of bacterial transport from the surface or topsoil for colonization and maturation of downstream compartments. This initial colonization of pristine surfaces is the major step in forming biogeochemical interfaces - the prominent locations of intensive biological activity and element turnover that seem to play a major role for the functioning of soil.
    Keywords: Mobile Organic Matter ; Unsaturated Two-Layer Column Experiment ; Experimental Pedogenesis ; Artificial Soil ; Computed Micro-Tomography ; Molecular Analysis ; Agriculture
    ISSN: 0016-7061
    E-ISSN: 1872-6259
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  • 5
    Conference Proceeding
    Conference Proceeding
    Editorial Universitat Politècnica de València
    Language: English
    Description: [EN] The project "DiverCity" observes spatial diversity in cities from an intersectional point of view and analyzesdifferent forms of urban life with an interdisciplinary approach. The main reason for this research is given by raising sociocultural coexistences living together in urban spaces; a subject that occupies the man from the beginning of his settlements, actually since the early development of cities. In spite of the social changes that are produced within modern urban lifes, the debate about social life very often seems more a matter rooted in politics than in everyday life itself. Societies generate solutions and create its own concept of coexistence, very since allowing joint relationships between different spheres and social groups. But how is this actually done? These dynamics are precisely the main object of investigation in the "DiverCity" project. It therefore focuses its study on socio-cultural minorities and their perception of urban space. This is basically examined in two cities of different dimensions, a small and larger city in Germany, Lüneburg and Hamburg. The investigated minority groups are Muslims, people with disabilities, homeless people and homosexuals. Using empirical social research methods, especially based on semi-structured interviews and participant observation, the urban and spatial perception of the mentioned groups was examined and compared to each other. The presentation shows the first results of the analyzes carried out in Hamburg and Lüneburg as well as the planned extension of the project and its realization in Argentina.
    Keywords: Urban Diversity ; Interculturality ; Urban Spatial Perception ; Participatory Observation
    Source: Universitat Politècnica de València
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  • 6
    Language: German
    In: Psychotherapeut, 2011, Vol.56(5), pp.386-393
    Description: Byline: Susanne Singer (1,859,5,859), Sylvia Hohlfeld (2,859), Daniel Muller-Briel (3,859), Andreas Dietz (4,859), Elmar Brahler (5,859), Katharina Schroter (5,859), Antje Lehmann-Laue (5,859) Keywords: Gewebsneubildung; Versorgungsforschung; Universitatskrankenhauser; Beratung; Konsil-/Liaisondienst; Neoplasm; Health services research; University hospitals; Counseling; Consultation-Liaison-Service Abstract (German): Ziel Ziel dieser Studie war es, Daten zur psychoonkologischen Versorgungssituation von Krebspatienten im ambulanten und im stationaren Bereich unter Routinebedingungen zu gewinnen. Dabei interessierten vorrangig die Versorgungsdichte sowie der Bedarf an und der Wunsch nach psychosozialer Versorgung. Methode Die Versorgungsdichte wurde anhand des Vergleichs von Inzidenzzahlen des Tumorregisters Leipzig, der Zahl der durch den psychoonkologischen Konsil-/Liaisondienst des Universitatsklinikums Leipzig betreuten Patienten und der Zahl der Ratsuchenden in der an der Universitat angesiedelten ambulanten Krebsberatungsstelle im Jahr 2008 ermittelt. Bedarf an und Wunsch nach psychosozialer Hilfe wurden anhand von Daten einer Patientenbefragung am gleichen Klinikum untersucht. Ergebnisse Im stationaren und im ambulanten Bereich wurden jeweils 11% der Krebspatienten psychoonkologisch betreut. Demgegenuber stehen ein sozialer Hilfebedarf bei 37% und ein psychologischer Hilfebedarf bei 52% der Patienten wahrend des Krankenhausaufenthalts (1/2 Jahr spater: je 42%). Insgesamt 41% der Befragten wunschten sich zu Beginn des Krankenhausaufenthalts Hilfe von einem Sozialarbeiter und 29% von einem Psychologen. Zwischen Patienten verschiedener Tumorentitaten bestanden grosse Unterschiede hinsichtlich der Versorgungssituation. Schlussfolgerung Im Vergleich zum Hilfebedarf und ihren Versorgungswunschen waren die Krebspatienten unter Routinebedingungen in einem Krankenhauses der Maximalversorgung als psychoonkologisch deutlich unterversorgt einzuschatzen. Abstract: Objectives The aim of this study was to determine rates of psychooncological care for cancer inpatients and outpatients under routine conditions in a large University hospital. The percentage of patients who received care was analyzed and compared with self-rated and expert rated supportive care needs. Methods The percentage of inpatients who received psychooncological care was calculated by comparing the number of cancer patients treated at the hospital as documented by the local tumor registry (n=1,979) with the number of patients treated by a psychooncologist in that hospital as documented by the hospital's psychooncological consultation liaison service. The percentage of outpatients who received psychooncological care was calculated by comparing the number of incident cancer cases as documented by the local tumor registry (n=5,886) with the number of patients who received at least one consultation at the local tumor counseling centre. Supportive care needs were estimated by analyzing data of a prospective patient survey in the same hospital (n=1,803) using the Hospital Anxiety and Depression Scale and single items to determine social burden and the wish for emotional support. Results The results showed that 11% of inpatients and outpatients (n=234 and n=638, respectively) received psychooncological care. Social care needs were prevalent in 37% and psychological care needs in 52% of the patients during the stay in hospital and in 42% (social and psychological) 6 months later. Of the patients 41% expressed the need to see a social worker and 29% to see a psychologist. Large differences were found between patients with different tumor entities. Conclusion Psychooncological care delivered to cancer patients under routine conditions was below the actual rate required as estimated by screening instruments and as expressed by the patients. Author Affiliation: (1859) Abt. Gesundheitspsychologie und Angewandte Diagnostik, Bergische Universitat Wuppertal, Gaussstr. 20, 42119, Wuppertal, Deutschland (2859) Tumorzentrum, Universitatsklinikum Leipzig, Leipzig, Deutschland (3859) Bereich Informationsmanagement, Universitatsklinikum Leipzig, Leipzig, Deutschland (4859) Klinik und Poliklinik fur Hals-Nasen-Ohrenheilkunde, Universitatsklinikum Leipzig, Leipzig, Deutschland (5859) Abteilung Medizinische Psychologie und Medizinische Soziologie, Universitat Leipzig, Leipzig, Deutschland Article History: Registration Date: 04/08/2011 Online Date: 27/08/2011
    Keywords: Neoplasm ; Health services research ; University hospitals ; Counseling ; Consultation-Liaison-Service
    ISSN: 0935-6185
    E-ISSN: 1432-2080
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  • 7
    In: International Journal of Urology, June 2013, Vol.20(6), pp.585-592
    Description: Byline: Sandra Steffens, Kristina I Ringe, Katharina Schroeer, Rieke Lehmann, Julia Rustemeier, Gerd Wegener, Mark Schrader, Rainer Hofmann, Markus A Kuczyk, Andres J Schrader, Keywords: body mass index; body surface area; obesity; prognosis; renal cell carcinoma; risk factors; visceral fat Objectives To assess the impact of overweight on prognosis of renal cell carcinoma patients. Patients And Methods A total of 2030 patients who underwent surgery for renal cell carcinoma from 1990 to 2011 in three University Medical Centers were included in this retrospective analysis. For all patients, height and weight measurements at the time of diagnosis were available for review. The median (mean) follow up was 56.6 months (66.0 months). Results A low body mass index was significantly associated with poor tumor differentiation, histology, microscopic vascular invasion and metastatic disease at the time of diagnosis. A lower-than-average body surface area - stratified according to the European average for men (1.98m.sub.2) and women (1.74m.sub.2) - was significantly related to older age, poor tumor differentiation, the histological subtype and microscopic vascular invasion. In addition, a low visceral fat area calculated in a subgroup of 133 evaluable patients was associated with a higher risk of advanced disease (pT3-4 and/or N/M+) at diagnosis. The tumor-specific 5-year survival rate was 71.3, 78.7 and 80.1%, for patients with a body mass index of, 〈25, 25-30 and a[yen]30. Multivariate analysis confirmed body mass index as an independent prognostic factor. Conclusion Our findings suggest that overweight represents an independent prognostic factor in renal cell carcinoma patients. Further research should address the question of why obese people have a higher incidence of renal cell carcinoma, but at the same time a significantly better prognosis than other patients, particularly in the case of localized disease. Author Affiliation:
    Keywords: Body Mass Index ; Body Surface Area ; Obesity ; Prognosis ; Renal Cell Carcinoma ; Risk Factors ; Visceral Fat
    ISSN: 0919-8172
    E-ISSN: 1442-2042
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  • 8
    Language: English
    In: BMC medical education, 17 April 2014, Vol.14, pp.82
    Description: Nursing staff are often involved in counseling patients with regard to health behavior. Although care promoting healthy lifestyle choices is included in the curriculum of nursing students in Germany, several studies of nursing students have reported a high prevalence of unhealthy behavior. This paper focuses on the behavior of female nursing students with regard to body mass index (BMI), physical activity, and cigarette and alcohol consumption. It describes trends through the comparison of results from 2008 and 2013. Data was collected in two waves at a regional medical training college. First, 301 nursing students were asked to fill out a 12 page questionnaire on health behavior in 2008. The questioning was repeated in 2013 with 316 participating nursing students using the previous questionnaire. 259 female nursing students completed the questionnaire in 2013. 31.6% of them were either overweight or obese, 28.5% exercised less than once a week, 42.9% smoked between 10 and 20 cigarettes a day and 72.6% drank alcohol, wherefrom 19.7% consumed alcohol in risky quantities. In comparison to the data of 266 female nursing students from 2008, there were significant differences in the BMI and alcohol consumption: The percentage of overweight and obese students and the percentage of alcohol consumers at risk increased significantly. Health behavior of female nursing students is often inadequate especially in regard to weight and cigarette and alcohol consumption. Strategies are required to promote healthy lifestyle choices.
    Keywords: Body Mass Index ; Sedentary Behavior ; Alcohol Drinking -- Epidemiology ; Smoking -- Epidemiology ; Students, Nursing -- Statistics & Numerical Data
    E-ISSN: 1472-6920
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  • 9
    Language: English
    In: Physical review. E, Statistical, nonlinear, and soft matter physics, May 2006, Vol.73(5 Pt 2), pp.056108
    Description: In this paper we formalize the small-world effect which describes the surprising fact that a hybrid graph composed of a local graph component and a very sparse random graph has a diameter of O(ln n) whereby the diameter of both components alone is much higher. We show that a large family of these hybrid graphs shows this effect and that this generalized family also includes classic small-world models proposed by various authors although not all of them are captured by the small-world definition given by Watts and Strogatz. Furthermore, we give a detailed upper bound of the hybrid's graph diameter for different choices of the expected number of random edges by applying a new kind of proof pattern that is applicable to a large number of hybrid graphs. The focus in this paper is on presenting a flexible family of hybrid graphs showing the small-world effect that can be tuned closely to real-world systems.
    Keywords: Physics;
    ISSN: 1539-3755
    E-ISSN: 15502376
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  • 10
    Language: English
    In: The Journal of cell biology, 16 February 2004, Vol.164(4), pp.501-7
    Description: During the past years, yeast has been successfully established as a model to study mechanisms of apoptotic regulation. However, the beneficial effects of such a cell suicide program for a unicellular organism remained obscure. Here, we demonstrate that chronologically aged yeast cultures die exhibiting typical markers of apoptosis, accumulate oxygen radicals, and show caspase activation. Age-induced cell death is strongly delayed by overexpressing YAP1, a key transcriptional regulator in oxygen stress response. Disruption of apoptosis through deletion of yeast caspase YCA1 initially results in better survival of aged cultures. However, surviving cells lose the ability of regrowth, indicating that predamaged cells accumulate in the absence of apoptotic cell removal. Moreover, wild-type cells outlast yca1 disruptants in direct competition assays during long-term aging. We suggest that apoptosis in yeast confers a selective advantage for this unicellular organism, and demonstrate that old yeast cells release substances into the medium that stimulate survival of the clone.
    Keywords: Aging -- Physiology ; Apoptosis -- Physiology ; Saccharomyces Cerevisiae -- Physiology
    ISSN: 0021-9525
    E-ISSN: 15408140
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