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  • 1
    Language: German
    In: Psychotherapeut, 2011, Vol.56(5), pp.386-393
    Description: Byline: Susanne Singer (1,859,5,859), Sylvia Hohlfeld (2,859), Daniel Muller-Briel (3,859), Andreas Dietz (4,859), Elmar Brahler (5,859), Katharina Schroter (5,859), Antje Lehmann-Laue (5,859) Keywords: Gewebsneubildung; Versorgungsforschung; Universitatskrankenhauser; Beratung; Konsil-/Liaisondienst; Neoplasm; Health services research; University hospitals; Counseling; Consultation-Liaison-Service Abstract (German): Ziel Ziel dieser Studie war es, Daten zur psychoonkologischen Versorgungssituation von Krebspatienten im ambulanten und im stationaren Bereich unter Routinebedingungen zu gewinnen. Dabei interessierten vorrangig die Versorgungsdichte sowie der Bedarf an und der Wunsch nach psychosozialer Versorgung. Methode Die Versorgungsdichte wurde anhand des Vergleichs von Inzidenzzahlen des Tumorregisters Leipzig, der Zahl der durch den psychoonkologischen Konsil-/Liaisondienst des Universitatsklinikums Leipzig betreuten Patienten und der Zahl der Ratsuchenden in der an der Universitat angesiedelten ambulanten Krebsberatungsstelle im Jahr 2008 ermittelt. Bedarf an und Wunsch nach psychosozialer Hilfe wurden anhand von Daten einer Patientenbefragung am gleichen Klinikum untersucht. Ergebnisse Im stationaren und im ambulanten Bereich wurden jeweils 11% der Krebspatienten psychoonkologisch betreut. Demgegenuber stehen ein sozialer Hilfebedarf bei 37% und ein psychologischer Hilfebedarf bei 52% der Patienten wahrend des Krankenhausaufenthalts (1/2 Jahr spater: je 42%). Insgesamt 41% der Befragten wunschten sich zu Beginn des Krankenhausaufenthalts Hilfe von einem Sozialarbeiter und 29% von einem Psychologen. Zwischen Patienten verschiedener Tumorentitaten bestanden grosse Unterschiede hinsichtlich der Versorgungssituation. Schlussfolgerung Im Vergleich zum Hilfebedarf und ihren Versorgungswunschen waren die Krebspatienten unter Routinebedingungen in einem Krankenhauses der Maximalversorgung als psychoonkologisch deutlich unterversorgt einzuschatzen. Abstract: Objectives The aim of this study was to determine rates of psychooncological care for cancer inpatients and outpatients under routine conditions in a large University hospital. The percentage of patients who received care was analyzed and compared with self-rated and expert rated supportive care needs. Methods The percentage of inpatients who received psychooncological care was calculated by comparing the number of cancer patients treated at the hospital as documented by the local tumor registry (n=1,979) with the number of patients treated by a psychooncologist in that hospital as documented by the hospital's psychooncological consultation liaison service. The percentage of outpatients who received psychooncological care was calculated by comparing the number of incident cancer cases as documented by the local tumor registry (n=5,886) with the number of patients who received at least one consultation at the local tumor counseling centre. Supportive care needs were estimated by analyzing data of a prospective patient survey in the same hospital (n=1,803) using the Hospital Anxiety and Depression Scale and single items to determine social burden and the wish for emotional support. Results The results showed that 11% of inpatients and outpatients (n=234 and n=638, respectively) received psychooncological care. Social care needs were prevalent in 37% and psychological care needs in 52% of the patients during the stay in hospital and in 42% (social and psychological) 6 months later. Of the patients 41% expressed the need to see a social worker and 29% to see a psychologist. Large differences were found between patients with different tumor entities. Conclusion Psychooncological care delivered to cancer patients under routine conditions was below the actual rate required as estimated by screening instruments and as expressed by the patients. Author Affiliation: (1859) Abt. Gesundheitspsychologie und Angewandte Diagnostik, Bergische Universitat Wuppertal, Gaussstr. 20, 42119, Wuppertal, Deutschland (2859) Tumorzentrum, Universitatsklinikum Leipzig, Leipzig, Deutschland (3859) Bereich Informationsmanagement, Universitatsklinikum Leipzig, Leipzig, Deutschland (4859) Klinik und Poliklinik fur Hals-Nasen-Ohrenheilkunde, Universitatsklinikum Leipzig, Leipzig, Deutschland (5859) Abteilung Medizinische Psychologie und Medizinische Soziologie, Universitat Leipzig, Leipzig, Deutschland Article History: Registration Date: 04/08/2011 Online Date: 27/08/2011
    Keywords: Neoplasm ; Health services research ; University hospitals ; Counseling ; Consultation-Liaison-Service
    ISSN: 0935-6185
    E-ISSN: 1432-2080
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  • 2
    Language: English
    In: PLoS ONE, Dec 26, 2014, Vol.9(12)
    Description: Background Systematic reviews of preclinical studies, in vivo animal experiments in particular, can influence clinical research and thus even clinical care. Dissemination bias, selective dissemination of positive or significant results, is one of the major threats to validity in systematic reviews also in the realm of animal studies. We conducted a systematic review to determine the number of published systematic reviews of animal studies until present, to investigate their methodological features especially with respect to assessment of dissemination bias, and to investigate the citation of preclinical systematic reviews on clinical research. Methods Eligible studies for this systematic review constitute systematic reviews that summarize in vivo animal experiments whose results could be interpreted as applicable to clinical care. We systematically searched Ovid Medline, Embase, ToxNet, and ScienceDirect from 1.sup.st January 2009 to 9.sup.th January 2013 for eligible systematic reviews without language restrictions. Furthermore we included articles from two previous systematic reviews by Peters et al. and Korevaar et al. Results The literature search and screening process resulted in 512 included full text articles. We found an increasing number of published preclinical systematic reviews over time. The methodological quality of preclinical systematic reviews was low. The majority of preclinical systematic reviews did not assess methodological quality of the included studies (71%), nor did they assess heterogeneity (81%) or dissemination bias (87%). Statistics quantifying the importance of clinical research citing systematic reviews of animal studies showed that clinical studies referred to the preclinical research mainly to justify their study or a future study (76%). Discussion Preclinical systematic reviews may have an influence on clinical research but their methodological quality frequently remains low. Therefore, systematic reviews of animal research should be critically appraised before translating them to a clinical context.
    Keywords: Animal Experimentation -- Research
    ISSN: 1932-6203
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  • 3
    Language: English
    In: PLoS ONE, Dec 26, 2014, Vol.9(12)
    Description: Background Systematic reviews of preclinical studies, in vivo animal experiments in particular, can influence clinical research and thus even clinical care. Dissemination bias, selective dissemination of positive or significant results, is one of the major threats to validity in systematic reviews also in the realm of animal studies. We conducted a systematic review to determine the number of published systematic reviews of animal studies until present, to investigate their methodological features especially with respect to assessment of dissemination bias, and to investigate the citation of preclinical systematic reviews on clinical research. Methods Eligible studies for this systematic review constitute systematic reviews that summarize in vivo animal experiments whose results could be interpreted as applicable to clinical care. We systematically searched Ovid Medline, Embase, ToxNet, and ScienceDirect from 1.sup.st January 2009 to 9.sup.th January 2013 for eligible systematic reviews without language restrictions. Furthermore we included articles from two previous systematic reviews by Peters et al. and Korevaar et al. Results The literature search and screening process resulted in 512 included full text articles. We found an increasing number of published preclinical systematic reviews over time. The methodological quality of preclinical systematic reviews was low. The majority of preclinical systematic reviews did not assess methodological quality of the included studies (71%), nor did they assess heterogeneity (81%) or dissemination bias (87%). Statistics quantifying the importance of clinical research citing systematic reviews of animal studies showed that clinical studies referred to the preclinical research mainly to justify their study or a future study (76%). Discussion Preclinical systematic reviews may have an influence on clinical research but their methodological quality frequently remains low. Therefore, systematic reviews of animal research should be critically appraised before translating them to a clinical context.
    Keywords: Animal Experimentation – Research
    ISSN: 1932-6203
    Source: Cengage Learning, Inc.
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  • 4
    Language: German
    Description: Ziel der Studie: Ziel dieser Studie war es, Daten zur psychoonkologischen Versorgungssituation von Krebspatienten im ambulanten und stationären Bereich unter Routinebedingungen zu gewinnen. Dabei interessierten vorrangig die Versorgungsdichte sowie der Bedarf an und der Wunsch nach psychosozialer[for full text, please go to the a.m. URL]...
    Keywords: Krebs; Versorgung; Versorgungsdichte; Psychoonkologie ; Medical Sciences; Medicine
    Source: DataCite
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