Kooperativer Bibliotheksverbund

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Language: English

Keywords: Kallikreine ; Proteasen ; Tumormarker

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Format: 190 S , Ill., graph. Darst

Note: München, Univ., Diss., 1988

Language: Undetermined

Keywords: Hochschulschrift

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Format: 190 S. , Ill., graph. Darst.

Note: München, Univ., Diss., 1988

Language: German

Keywords: Saccharomyces cerevisiae ; Genanalyse ; Saccharomyces cerevisiae ; Transkription ; Hochschulschrift

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Format: 190 S. : Ill., graph. Darst.

Note: München, Univ., Diss., 1988

Language: German

Keywords: Saccharomyces cerevisiae ; Genanalyse ; Saccharomyces cerevisiae ; Transkription ; Hochschulschrift

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Format: xvii, 409 p. : , ill.

Edition: Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.

Note: Genomic structure of the KLK locus -- Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases -- Evolution of Kallikrein-related peptidases -- Structural aspects of Kallikrein-related peptidases -- Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates -- Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases -- Kallikrein-related peptidases as pharmaceutical targets -- Expression of Kallikrein-related peptidases under (patho) physiological conditions -- Kallikrein-related peptidases within the proteolytic web -- Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1) -- Role of KLK4 in dental enamel formation. , Kallikrein-related peptidases and semen -- Kallikrein-related peptidases and inhibitors of the skin -- Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system -- Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS) -- Pathophysiology of Kallikrein-related peptidases in lung cancer -- Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer -- Pathophysiology of Kallikrein-related peptidases in head and neck cancer -- PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer -- Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer -- Clinical relevance of Kallikrein-related peptidases in breast cancer -- Clinical relevance of Kallikrein-related peptidases in ovarian cancer -- MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers -- Genomic instability of the KLK-locus in cancer -- Kallikrein-related peptidases as biomarkers in personalized cancer medicine.

Language: English

Keywords: Electronic books.

URL: Click to View

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Format: xv, 226 p. : , ill. (some col.).

Edition: Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.

Series Statement: Kallikrein-related peptidases ; v. 2

Language: English

Keywords: Electronic books.

URL: Click to View

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Format: 190 S. : Ill., graph. Darst.

Note: München, Univ., Diss., 1988

Language: German

Keywords: Saccharomyces cerevisiae ; Genanalyse ; Saccharomyces cerevisiae ; Transkription ; Hochschulschrift

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Format: 1 online resource (242 p.)

Edition: 1st ed.

ISBN: 3-11-048153-7 , 3-11-030366-3

Series Statement: Kallikrein-related peptidases ; v. 2

Content: Various KLK proteins and their encoding genes have attracted increased attention among scientists and clinicians worldwide since they represent very interesting and functionally distinct biomarkers, particularly, in cancer. This book reviews the role of kallikrein-related peptidases (KLKs) in a wide range of cancers, including lung, prostate, breast and ovarian cancer. It provides clinicians, physician scientists and researchers with a comprehensive overview on the clinical relevance of KLK expression in various malignancies.

Note: Frontmatter -- , Preface -- , List of contributing authors -- , Table of Contents -- , Introduction to Volume 2: Kallikrein-related Peptidases. Novel Cancer-related Biomarkers / , 1 Pathophysiology of Kallikrein-related Peptidases in Lung Cancer / , 2 Clinical Relevance of Kallikrein-related Peptidases in Gastric and Colorectal Cancer / , 3 Pathophysiology of Kallikrein-related Peptidases in Head and Neck Cancer / , 4 PSA (Prostate-Specific Antigen) and other Kallikrein-related Peptidases in Prostate Cancer / , 5 Cellular Model Systems to Study the Tumor Biological Role of Kallikrein-related Peptidases in Ovarian and Prostate Cancer / , 6 Clinical Relevance of Kallikrein-related Peptidases in Breast Cancer / , 7 Clinical Relevance of Kallikrein-related Peptidases in Ovarian Cancer / , 8 microRNAs: A New Control Mechanism for Kallikrein-related Peptidases in Kidney and Other Cancers / , 9 Genomic Instability of the KLK-locus in Cancer / , 10 Kallikrein-related Peptidases as Biomarkers in Personalized Cancer Medicine / , Index , In English.

Additional Edition: ISBN 3-11-030358-2

Additional Edition: ISBN 1-299-71949-X

Language: English

Subjects: Biology

DOI: 10.1515/9783110303667

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Format: 1 online resource (428 p.)

Edition: 1st ed.

ISBN: 3-11-026037-9

Series Statement: Kallikrein-related peptidases ; Volume 1

Content: This handbook is the first comprehensive book of its kind reviewing the clinically relevant current status of tissue kallikrein and kallikrein-related peptidases research. Since several members of the KLK family are key players in (patho-)physiological processes, structural, functional, and regulatory studies are under way to develop new strategies to prevent and treat disorders to which individual members of the KLK protease family contribute significantly. The goal of this book is to inform clinicians, physician scientists and researchers about the prominent role of the multifaceted and interactive KLK system in normal physiology and pathological organ function.

Note: Description based upon print version of record. , Genomic structure of the KLK locus -- Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases -- Evolution of Kallikrein-related peptidases -- Structural aspects of Kallikrein-related peptidases -- Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates -- Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases -- Kallikrein-related peptidases as pharmaceutical targets -- Expression of Kallikrein-related peptidases under (patho) physiological conditions -- Kallikrein-related peptidases within the proteolytic web -- Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1) -- Role of KLK4 in dental enamel formation. , Kallikrein-related peptidases and semen -- Kallikrein-related peptidases and inhibitors of the skin -- Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system -- Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS) -- Pathophysiology of Kallikrein-related peptidases in lung cancer -- Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer -- Pathophysiology of Kallikrein-related peptidases in head and neck cancer -- PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer -- Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer -- Clinical relevance of Kallikrein-related peptidases in breast cancer -- Clinical relevance of Kallikrein-related peptidases in ovarian cancer -- MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers -- Genomic instability of the KLK-locus in cancer -- Kallikrein-related peptidases as biomarkers in personalized cancer medicine. , English

Additional Edition: ISBN 3-11-048151-0

Additional Edition: ISBN 3-11-026036-0

Language: English

Subjects: Biology

DOI: 10.1515/9783110260373

UID:

Format: 1 online resource (426p.)

ISBN: 9783110260373

Series Statement: Kallikrein-related peptidases ; Volume 1

Content: The KLK proteins and their encoding genes are increasingly attracting attention among scientists and clinicians worldwide as they represent interesting and functionally distinct biomarkers both under physiological and pathophysiological conditions. This volume on kallikrein-related peptidases (KLKs) reviews the characterization, regulation, and interactions of these proteases within the protease web.

Note: Frontmatter -- , Preface -- , List of contributing authors -- , Table of Contents -- , Introduction to Volume 1: Kallikrein-related Peptidases. Characterization, Regulation, and Interactions Within the Protease Web -- , 1 Genomic Structure of the KLK Locus -- , 2 Single Nucleotide Polymorphisms in the Human KLK Locus and Their Implication in Various Diseases -- , 3 Evolution of Kallikrein-related Peptidases -- , 4 Structural Aspects of Kallikrein-related Peptidases -- , 5 Molecular Recognition Properties of Kallikrein-related Peptidases on Synthetic and Endogenous Substrates -- , 6 Natural, Engineered and Synthetic Inhibitors of Kallikrein-related Peptidases -- , 7 Kallikrein-related Peptidases as Pharmaceutical Targets -- , 8 Expression of Kallikrein-related Peptidases under (Patho-)Physiological Conditions -- , 9 Kallikrein-related Peptidases within the Proteolytic Web -- , 10 Kallikrein-Kinin Cascade: Bioregulation by Human Tissue Kallikrein 1 (hK1, KLK1) -- , 11 Role of KLK4 in Dental Enamel Formation -- , 12 Kallikrein-related Peptidases and Semen -- , 13 Kallikrein-related Peptidases and Inhibitors of the Skin -- , 14 Physiological and Pathophysiological Roles of Kallikrein-related Peptidases in the Central Nervous System -- , 15 Kallikrein-related Peptidases (KLKs), Proteinase-mediated Signaling and Proteinase-activated Receptors (PARs) -- , Index , In English.

Additional Edition: ISBN 978-3-11-026036-6

Language: English

DOI: 10.1515/9783110260373

URL: https://doi.org/10.1515/9783110260373