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  • 1
    UID:
    gbv_1794552022
    Format: 1 Online-Ressource (408 p.)
    ISBN: 9780262314602 , 9780262019620
    Series Statement: Strüngmann Forum Reports 13
    Content: Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability. Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes
    Note: English
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    UID:
    gbv_371304210
    Format: XIV, 487 S , Ill., graph. Darst
    ISBN: 1573314765 , 1573314773
    Series Statement: Annals of the New York Academy of Sciences 1003
    Note: Papers from a conference held on Apr. 13-15, 2003 in New Haven, Conn. by the New York Academy of Sciences and cosponsored by the National Institute of Mental Health and Eli Lilly and Company - Includes bibliographical references and index
    Language: English
    Keywords: Motivation ; Störung ; Glutamate ; Kognitive Störung ; Glutamate ; Neurotransmitter ; Kognition ; Antrieb ; Konferenzschrift
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  • 3
    Online Resource
    Online Resource
    Cambridge, Massachusetts ; : The MIT Press,
    UID:
    almahu_9949253559402882
    Format: 1 online resource (390 pages).
    ISBN: 9781461952350 , 1461952352 , 9781306140652 , 130614065X , 9780262314602 , 0262314606
    Series Statement: Strüngmann Forum reports
    Content: Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last 50 years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cambridge, Massachusetts : MIT Press
    UID:
    b3kat_BV047300663
    Format: 1 Online-Ressource (xiv, 182 Seiten)
    ISBN: 9780262363600
    Series Statement: MIT press essential knowledge series
    Note: Bevorzugte Informationsquelle: Landingpage (The MIT Press Direct), da weder Titelblatt noch Impressum vorhanden
    Additional Edition: Erscheint auch als Druck-Ausgabe, Paperback ISBN 978-0-262-54224-1
    Language: English
    Subjects: Psychology
    RVK:
    RVK:
    Keywords: Ketamin
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 5
    Book
    Book
    Cambridge ; London :The MIT Press,
    UID:
    almahu_BV047156304
    Format: xiv, 182 Seiten : , Illustrationen, Diagramme.
    ISBN: 978-0-262-54224-1
    Series Statement: MIT press essential knowledge series
    Additional Edition: Erscheint auch als Online-Ausgabe ISBN 978-0-262-36360-0
    Language: English
    Subjects: Psychology
    RVK:
    RVK:
    Keywords: Ketamin
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  • 6
    Online Resource
    Online Resource
    Cambridge, Massachusetts ; : The MIT Press,
    UID:
    edocfu_9959236113002883
    Format: 1 online resource (403 p.)
    ISBN: 0-262-31460-6
    Series Statement: Strüngmann Forum reports
    Content: Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last 50 years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.
    Note: Description based upon print version of record. , Contents; The Ernst Strüngmann Forum; List of Contributors; 1 Schizophrenia; Heterogeneity; 2 What Kind of a Thing Is Schizophrenia?; 3 How the Diagnosis of Schizophrenia Impeded the Advance of Knowledge (and What to Do About It); 4 What Dimensions of Heterogeneity Are Relevant for Treatment Outcome?; 5 Which Aspects of Heterogeneity Are Useful to Translational Success?; Risk and Resilience; 6 How Should Resilience Factors Be Incorporated in Treatment Development?; 7 Insights into New Treatments for Early Psychosis from Genetic, Neurodevelopment,and Cognitive Neuroscience Research , 8 From Epidemiology to Mechanisms of Illness9 How Can Risk and Resilience Factors Be Leveraged to Optimize Discovery Pathways?; Models; 10 Human Cell Models for Schizophrenia; 11 How Can Animal Models Be Better Utilized?; 12 How Can Computational Models Be Better Utilized for Understanding and Treating Schizophrenia?; 13 How Can Models Be Better Utilized to Enhance Outcome?; Development and Treatment; 14 Why Kraepelin Was Right; 15 What Will the Next Generation of Psychosocial Treatments Look Like?; 16 Creative Solutions to Overcoming Barriers in Treatment Utilization , 17 What Is Necessary to Enhance Development and Utilization of Treatment?Bibliography; Subject Index , English
    Additional Edition: ISBN 0-262-01962-0
    Additional Edition: ISBN 1-306-14065-X
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 7
    Online Resource
    Online Resource
    Cambridge, Massachusetts ; : The MIT Press,
    UID:
    edoccha_9959236113002883
    Format: 1 online resource (403 p.)
    ISBN: 0-262-31460-6
    Series Statement: Strüngmann Forum reports
    Content: Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last 50 years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.
    Note: Description based upon print version of record. , Contents; The Ernst Strüngmann Forum; List of Contributors; 1 Schizophrenia; Heterogeneity; 2 What Kind of a Thing Is Schizophrenia?; 3 How the Diagnosis of Schizophrenia Impeded the Advance of Knowledge (and What to Do About It); 4 What Dimensions of Heterogeneity Are Relevant for Treatment Outcome?; 5 Which Aspects of Heterogeneity Are Useful to Translational Success?; Risk and Resilience; 6 How Should Resilience Factors Be Incorporated in Treatment Development?; 7 Insights into New Treatments for Early Psychosis from Genetic, Neurodevelopment,and Cognitive Neuroscience Research , 8 From Epidemiology to Mechanisms of Illness9 How Can Risk and Resilience Factors Be Leveraged to Optimize Discovery Pathways?; Models; 10 Human Cell Models for Schizophrenia; 11 How Can Animal Models Be Better Utilized?; 12 How Can Computational Models Be Better Utilized for Understanding and Treating Schizophrenia?; 13 How Can Models Be Better Utilized to Enhance Outcome?; Development and Treatment; 14 Why Kraepelin Was Right; 15 What Will the Next Generation of Psychosocial Treatments Look Like?; 16 Creative Solutions to Overcoming Barriers in Treatment Utilization , 17 What Is Necessary to Enhance Development and Utilization of Treatment?Bibliography; Subject Index , English
    Additional Edition: ISBN 0-262-01962-0
    Additional Edition: ISBN 1-306-14065-X
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 8
    Online Resource
    Online Resource
    Cambridge, Massachusetts ; : The MIT Press,
    UID:
    almahu_9949281767002882
    Format: 1 online resource (403 p.)
    ISBN: 0-262-31460-6
    Series Statement: Strüngmann Forum reports
    Content: Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last 50 years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.
    Note: Description based upon print version of record. , Contents; The Ernst Strüngmann Forum; List of Contributors; 1 Schizophrenia; Heterogeneity; 2 What Kind of a Thing Is Schizophrenia?; 3 How the Diagnosis of Schizophrenia Impeded the Advance of Knowledge (and What to Do About It); 4 What Dimensions of Heterogeneity Are Relevant for Treatment Outcome?; 5 Which Aspects of Heterogeneity Are Useful to Translational Success?; Risk and Resilience; 6 How Should Resilience Factors Be Incorporated in Treatment Development?; 7 Insights into New Treatments for Early Psychosis from Genetic, Neurodevelopment,and Cognitive Neuroscience Research , 8 From Epidemiology to Mechanisms of Illness9 How Can Risk and Resilience Factors Be Leveraged to Optimize Discovery Pathways?; Models; 10 Human Cell Models for Schizophrenia; 11 How Can Animal Models Be Better Utilized?; 12 How Can Computational Models Be Better Utilized for Understanding and Treating Schizophrenia?; 13 How Can Models Be Better Utilized to Enhance Outcome?; Development and Treatment; 14 Why Kraepelin Was Right; 15 What Will the Next Generation of Psychosocial Treatments Look Like?; 16 Creative Solutions to Overcoming Barriers in Treatment Utilization , 17 What Is Necessary to Enhance Development and Utilization of Treatment?Bibliography; Subject Index , English
    Additional Edition: ISBN 0-262-01962-0
    Additional Edition: ISBN 1-306-14065-X
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 9
    Online Resource
    Online Resource
    Cambridge, Massachusetts ; : The MIT Press,
    UID:
    edocfu_9961267983902883
    Format: 1 online resource (202 pages).
    ISBN: 0-262-36360-7 , 0-262-36266-X
    Series Statement: MIT Press Essential Knowledge Series
    Content: "A complete and authoritative guide to the science of ketamine, the controversial yet current drug of choice for treating depression, a drug whose efficacy and impact is not yet well-established"--
    Note: The Molecule Ketamine -- Uses of Ketamine -- Neuroscience of Ketamine -- Ketamine as an Antidepressant -- How Does Ketamine Produce Antidepressant Effects -- Safety Concerns with Ketamine and Esketamine -- Where Do We Go From Here.
    Additional Edition: ISBN 0-262-54224-2
    Language: English
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