Kooperativer Bibliotheksverbund

UID:

Format: xii, 257 Seiten : , Illustrationen, Diagramme.

ISBN: 978-0-674-97101-1

Language: English

Subjects: Biology

Keywords: Taufliege ; Genetik ; Physiologie ; Tiermodell

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030109075&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030109075&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

UID:

Format: xxii, 235 Seiten : , Illustrationen, Diagramme.

Edition: Second edition

ISBN: 978-0-12-809473-0

Note: Includes bibliographical references and index

Language: English

Subjects: Biology

Keywords: Drosophila ; Zellkultur

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030118376&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

UID:

Format: 1 online resource (270 p.) : , 21 line illustrations, 1 table

ISBN: 9780674984721

Content: A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.

Note: Frontmatter -- , Contents -- , Preface -- , Introduction -- , MAPS -- , CHANGE -- , COMMUNICATION -- , SIZE -- , DIRECTION -- , DIFFERENCE -- , DEFENSES -- , BEHAVIOR -- , COORDINATION -- , CONTINUITY -- , Epilogue -- , APPENDIX A. How to Make a Flytrap -- , APPENDIX B: Comparable Organs in Humans and Flies -- , APPENDIX C: Selected Genetic Screens Performed in Drosophila -- , Recommended Reading -- , Abbreviations -- , References -- , Acknowledgments -- , Index , In English.

Language: English

DOI: 10.4159/9780674984721

URL: https://doi.org/10.4159/9780674984721

URL: https://www.degruyter.com/isbn/9780674984721

UID:

Format: 1 online resource (258 pages) : , illustrations, maps

ISBN: 0-674-98473-0 , 0-674-98472-2

Content: A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.--

Note: Frontmatter -- , Contents -- , Preface -- , Introduction -- , MAPS -- , CHANGE -- , COMMUNICATION -- , SIZE -- , DIRECTION -- , DIFFERENCE -- , DEFENSES -- , BEHAVIOR -- , COORDINATION -- , CONTINUITY -- , Epilogue -- , APPENDIX A. How to Make a Flytrap -- , APPENDIX B: Comparable Organs in Humans and Flies -- , APPENDIX C: Selected Genetic Screens Performed in Drosophila -- , Recommended Reading -- , Abbreviations -- , References -- , Acknowledgments -- , Index , In English.

Additional Edition: ISBN 0-674-97101-9

Language: English

DOI: 10.4159/9780674984721

UID:

Format: 1 online resource (235 pages) : , illustrations

Edition: Second edition.

ISBN: 0-12-809473-7

Note: Composition of the body fluid of drosophila and the design of culture media for drosophila cells / Guy Echalier -- Primary cell cultures of drosophila embryonic cells / Guy Echalier -- Continuous drosophila cell lines established in vitro / Guy Echalier -- Cells or tissues in course of differentiation / Guy Echalier -- Hormonal control of development of insects: implications in organ or cell cultures of drosophila / Guy Echalier -- Directed genetic methods for establishing continuous cell lines / Amanda Simcox -- Organ culture methods for the drosophila wing imaginal disc / Jeremiah J. Zartman -- Functional genomics screens in drosophila cells / Stephanie E. Mohr and Norbert Perrimon -- CRISPR-based perturbation of gene function in drosophila cells / Benjamin E. Housden, Benjamin Ewen-Campen, Stephanie E. Mohr, and Norbert Perrimon -- Compendium of drosophila cell line resources and plasmid vectors at the drosophila genome resource center / Lei Gong, Kris Klueg, Lucy Cherbas, and Andrew C. Zelhof.

Language: English

UID:

Format: 1 online resource (235 pages) : , illustrations

Edition: Second edition.

ISBN: 0-12-809473-7

Note: Composition of the body fluid of drosophila and the design of culture media for drosophila cells / Guy Echalier -- Primary cell cultures of drosophila embryonic cells / Guy Echalier -- Continuous drosophila cell lines established in vitro / Guy Echalier -- Cells or tissues in course of differentiation / Guy Echalier -- Hormonal control of development of insects: implications in organ or cell cultures of drosophila / Guy Echalier -- Directed genetic methods for establishing continuous cell lines / Amanda Simcox -- Organ culture methods for the drosophila wing imaginal disc / Jeremiah J. Zartman -- Functional genomics screens in drosophila cells / Stephanie E. Mohr and Norbert Perrimon -- CRISPR-based perturbation of gene function in drosophila cells / Benjamin E. Housden, Benjamin Ewen-Campen, Stephanie E. Mohr, and Norbert Perrimon -- Compendium of drosophila cell line resources and plasmid vectors at the drosophila genome resource center / Lei Gong, Kris Klueg, Lucy Cherbas, and Andrew C. Zelhof.

Language: English

UID:

Format: 1 online resource (235 pages) : , illustrations

Edition: Second edition.

ISBN: 0-12-809473-7

Note: Composition of the body fluid of drosophila and the design of culture media for drosophila cells / Guy Echalier -- Primary cell cultures of drosophila embryonic cells / Guy Echalier -- Continuous drosophila cell lines established in vitro / Guy Echalier -- Cells or tissues in course of differentiation / Guy Echalier -- Hormonal control of development of insects: implications in organ or cell cultures of drosophila / Guy Echalier -- Directed genetic methods for establishing continuous cell lines / Amanda Simcox -- Organ culture methods for the drosophila wing imaginal disc / Jeremiah J. Zartman -- Functional genomics screens in drosophila cells / Stephanie E. Mohr and Norbert Perrimon -- CRISPR-based perturbation of gene function in drosophila cells / Benjamin E. Housden, Benjamin Ewen-Campen, Stephanie E. Mohr, and Norbert Perrimon -- Compendium of drosophila cell line resources and plasmid vectors at the drosophila genome resource center / Lei Gong, Kris Klueg, Lucy Cherbas, and Andrew C. Zelhof.

Language: English