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  • 1
    UID:
    almahu_9949586949602882
    Format: 1 online resource (x, 171 pages) : , digital, PDF file(s).
    ISBN: 9781316335208 (ebook)
    Content: The volume and complexity of biological and biomedical research continues to grow exponentially with cutting-edge technologies such as high-throughput sequencing. Unfortunately, bioinformatics analysis is often considered only after data have been generated, which significantly limits the ability to make sense of complex big data. This unique book introduces the idea of No-Boundary Thinking (NBT) in biological and biomedical research, which aims to access, integrate, and synthesize data, information, and knowledge from bioinformatics to define important problems and articulate impactful research questions. This interdisciplinary volume brings together a team of bioinformatics specialists who draw on their own experiences with NBT to illustrate the importance of collaborative science. It will help stimulate discussion and application of NBT, and will appeal to all biomedical researchers looking to maximize their use of bioinformatics for making scientific discoveries.
    Note: Title from publisher's bibliographic system (viewed on 18 Sep 2023).
    Additional Edition: Print version: ISBN 9781107114302
    Language: English
    Subjects: Biology
    RVK:
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 2
    UID:
    almahu_9949251376002882
    Format: 1 online resource (X, 350 p. 61 illus., 17 illus. in color.)
    Edition: 1st ed. 2015.
    ISBN: 1-4939-2155-X
    Series Statement: Methods in Molecular Biology, 1253
    Content: This volume presents a valuable and readily reproducible collection of established and emerging techniques on modern genetic analyses. Chapters focus on statistical or data mining analyses, genetic architecture, the burden of multiple testing, genetic variance, measuring epistasis, multifactor dimensionality reduction, and ReliefF. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Epistasis: Methods and Protocols aids scientists in continuing to study elucidate epistasis in the context of modern data availability.
    Note: Bibliographic Level Mode of Issuance: Monograph , Long Term Selection Experiments: Epistasis and The Response To Selection -- Finding the Epistasis Needles in the Genome-Wide Haystack -- Biological Knowledge-Driven Analysis of Epistasis in Human GWAS with Application to Lipid Traits -- Epistasis for Quantitative Traits in Drosophila -- Epistasis In The Risk Of Human Neuropsychiatric Disease -- On the Partitioning of Genetic Variance with Epistasis -- Measuring Gene Interactions -- Two Rules for the Detection and Quantification of Epistasis and other Interaction Effects -- Direct Approach to Modeling Epistasis -- Capacitating Epistasis  - Detection and Role in the Genetic Architecture of Complex Traits -- Compositional Epistasis: An Epidemiologic Perspective -- Identification Of Genome—Wide SNP—SNP and SNP—Clinical Boolean Interactions In Age—Related Macular Degeneration -- Epistasis Analysis Using Information Theory -- Genome-Wide Epistasis and Pleiotropy Characterized by the Bipartite Human -- Network Theory for Data-Driven Epistasis Networks --  Epistasis Analysis Using Multifactor Dimensionality Reduction --  Epistasis Analysis Using ReliefF -- Epistasis Analysis Using Artificial Intelligence. , English
    Additional Edition: ISBN 1-4939-2154-1
    Language: English
    Keywords: Laboratory Manuals. ; Handbooks, manuals, etc. ; Laboratory Manuals. ; Handbooks, manuals, etc. ; Laboratory Manuals. ; Handbooks, manuals, etc. ; Laboratory Manuals. ; Handbooks, manuals, etc.
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  • 3
    Online Resource
    Online Resource
    New York ; Heidelberg ; Dordrecht ; London : Springer
    UID:
    b3kat_BV043209819
    Format: 1 Online Ressource (XIV, 227 Seiten) , Illustrationen
    ISBN: 9781493903757
    Series Statement: Genetic and Evolutionary Computation
    Additional Edition: Erscheint auch als Druckausgabe ISBN 978-1-4939-0374-0
    Language: English
    Subjects: Computer Science
    RVK:
    RVK:
    Keywords: Genetische Programmierung ; Aufsatzsammlung ; Konferenzschrift
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing, | Cham :Springer.
    UID:
    edocfu_BV049442602
    Format: 1 Online-Ressource (VI, 285 p. 80 illus., 58 illus. in color).
    Edition: 1st ed. 2023
    ISBN: 978-3-031-36678-9
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-031-36677-2
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-031-36679-6
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-031-36680-2
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 5
    UID:
    almahu_BV045215431
    Format: XIV, 227 Seiten : , Illustrationen, Diagramme.
    ISBN: 978-1-4939-0374-0
    Series Statement: Genetic and evolutionary computation
    Note: Aus dem Vorwort: "The work described in this book was first presented at the Eleventh Workshop on Genetic Programming, Theory and Practice, organized by the Center for the Study of Complex Systems at the University of Michigan, Ann Arbor, held on March 9-11.2013."
    Additional Edition: Erscheint auch als Online-ausgabe, eBook ISBN 978-1-4939-0375-7
    Language: English
    Subjects: Computer Science
    RVK:
    RVK:
    Keywords: Genetische Programmierung ; Aufsatzsammlung ; Konferenzschrift
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  • 6
    UID:
    almahu_BV045215401
    Format: XXVI, 242 Seiten : , Diagramme.
    ISBN: 978-1-4614-6845-5
    Series Statement: Genetic and evolutionary computation
    Additional Edition: Erscheint auch als Online-Ausgabe, eBook ISBN 978-1-4614-6846-2
    Language: English
    Subjects: Computer Science
    RVK:
    Keywords: Genetischer Algorithmus
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  • 7
    UID:
    almahu_BV049011616
    Format: x, 171 Seiten : , Illustrationen, Diagramme.
    ISBN: 9781107114302
    Language: English
    Subjects: Biology
    RVK:
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  • 8
    UID:
    almahu_9947364036402882
    Format: XI, 302 p. , online resource.
    ISBN: 9783540717836
    Series Statement: Lecture Notes in Computer Science, 4447
    Note: Identifying Regulatory Sites Using Neighborhood Species -- Genetic Programming and Other Machine Learning Approaches to Predict Median Oral Lethal Dose (LD50) and Plasma Protein Binding Levels (%PPB) of Drugs -- Hypothesis Testing with Classifier Systems for Rule-Based Risk Prediction -- Robust Peak Detection and Alignment of nanoLC-FT Mass Spectrometry Data -- One-Versus-One and One-Versus-All Multiclass SVM-RFE for Gene Selection in Cancer Classification -- Understanding Signal Sequences with Machine Learning -- Targeting Differentially Co-regulated Genes by Multiobjective and Multimodal Optimization -- Modeling Genetic Networks: Comparison of Static and Dynamic Models -- A Genetic Embedded Approach for Gene Selection and Classification of Microarray Data -- Modeling the Shoot Apical Meristem in A. thaliana: Parameter Estimation for Spatial Pattern Formation -- Evolutionary Search for Improved Path Diagrams -- Simplifying Amino Acid Alphabets Using a Genetic Algorithm and Sequence Alignment -- Towards Evolutionary Network Reconstruction Tools for Systems Biology -- A Gaussian Evolutionary Method for Predicting Protein-Protein Interaction Sites -- Bio-mimetic Evolutionary Reverse Engineering of Genetic Regulatory Networks -- Tuning ReliefF for Genome-Wide Genetic Analysis -- Dinucleotide Step Parameterization of Pre-miRNAs Using Multi-objective Evolutionary Algorithms -- Amino Acid Features for Prediction of Protein-Protein Interface Residues with Support Vector Machines -- Predicting HIV Protease-Cleavable Peptides by Discrete Support Vector Machines -- Inverse Protein Folding on 2D Off-Lattice Model: Initial Results and Perspectives -- Virtual Error: A New Measure for Evolutionary Biclustering -- Characterising DNA/RNA Signals with Crisp Hypermotifs: A Case Study on Core Promoters -- Evaluating Evolutionary Algorithms and Differential Evolution for the Online Optimization of Fermentation Processes -- The Role of a Priori Information in the Minimization of Contact Potentials by Means of Estimation of Distribution Algorithms -- Classification of Cell Fates with Support Vector Machine Learning -- Reconstructing Linear Gene Regulatory Networks -- Individual-Based Modeling of Bacterial Foraging with Quorum Sensing in a Time-Varying Environment -- Substitution Matrix Optimisation for Peptide Classification.
    In: Springer eBooks
    Additional Edition: Printed edition: ISBN 9783540717829
    Language: English
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  • 9
    UID:
    almahu_9947364179702882
    Format: X, 213 p. , online resource.
    ISBN: 9783540787570
    Series Statement: Lecture Notes in Computer Science, 4973
    Note: A Hybrid Random Subspace Classifier Fusion Approach for Protein Mass Spectra Classification -- Using Ant Colony Optimization-Based Selected Features for Predicting Post-synaptic Activity in Proteins -- Generating Linkage Disequilibrium Patterns in Data Simulations Using genomeSIMLA -- DEEPER: A Full Parsing Based Approach to Protein Relation Extraction -- Improving the Performance of Hierarchical Classification with Swarm Intelligence -- Protein Interaction Inference Using Particle Swarm Optimization Algorithm -- Divide, Align and Full-Search for Discovering Conserved Protein Complexes -- Detection of Quantitative Trait Associated Genes Using Cluster Analysis -- Frequent Subsplit Representation of Leaf-Labelled Trees -- Inference on Missing Values in Genetic Networks Using High-Throughput Data -- Mining Gene Expression Patterns for the Discovery of Overlapping Clusters -- Development and Evaluation of an Open-Ended Computational Evolution System for the Genetic Analysis of Susceptibility to Common Human Diseases -- Gene Selection and Cancer Microarray Data Classification Via Mixed-Integer Optimization -- Detection of Protein Complexes in Protein Interaction Networks Using n-Clubs -- Learning Gaussian Graphical Models of Gene Networks with False Discovery Rate Control -- Enhancing Parameter Estimation of Biochemical Networks by Exponentially Scaled Search Steps -- A Wrapper-Based Feature Selection Method for ADMET Prediction Using Evolutionary Computing -- On the Convergence of Protein Structure and Dynamics. Statistical Learning Studies of Pseudo Folding Pathways.
    In: Springer eBooks
    Additional Edition: Printed edition: ISBN 9783540787563
    Language: English
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  • 10
    UID:
    almahu_9947363939202882
    Format: XXIV, 816 p. , online resource.
    ISBN: 9783540332381
    Series Statement: Lecture Notes in Computer Science, 3907
    Note: EvoBIO Contributions -- EvoCOMNET Contributions -- EvoHOT Contributions -- EvoIASP Contributions -- EvoINTERACTION Contributions -- EvoMUSART Contributions -- EvoSTOC Contributions.
    In: Springer eBooks
    Additional Edition: Printed edition: ISBN 9783540332374
    Language: English
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