Kooperativer Bibliotheksverbund

Berlin Brandenburg

and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Language
Year
  • 1
    Language: English
    In: Transmission & Distribution World (Online Exclusive), Jan 19, 2010
    Keywords: Power Grids – Standards ; Electric Utilities – Standards ; Electric Utilities – Technology Application ; Electric Utilities – Services
    Source: Cengage Learning, Inc.
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    In: Journal of Advanced Nursing, February 2017, Vol.73(2), pp.349-360
    Description: Byline: Marliese Dion Nist Keywords: biological embedding; concept analysis; life course theory; nursing; toxic stress Abstract Aim The purpose of this paper was to report the analysis of the concept of biological embedding. Background Research that incorporates a life course perspective is becoming increasingly prominent in the health sciences. Biological embedding is a central concept in life course theory and may be important for nursing theories to enhance our understanding of health states in individuals and populations. Before the concept of biological embedding can be used in nursing theory and research, an analysis of the concept is required to advance it towards full maturity. Design Concept analysis. Data sources PubMed, CINAHL and PsycINFO were searched for publications using the term 'biological embedding' or 'biological programming' and published through 2015. Methods An evaluation of the concept was first conducted to determine the concept's level of maturity and was followed by a concept comparison, using the methods for concept evaluation and comparison described by Morse. Results A consistent definition of biological embedding - the process by which early life experience alters biological processes to affect adult health outcomes - was found throughout the literature. The concept has been used in several theories that describe the mechanisms through which biological embedding might occur and highlight its role in the development of health trajectories. Biological embedding is a partially mature concept, requiring concept comparison with an overlapping concept - biological programming - to more clearly establish the boundaries of biological embedding. Conclusions Biological embedding has significant potential for theory development and application in multiple academic disciplines, including nursing.
    Keywords: Biological Embedding ; Concept Analysis ; Life Course Theory ; Nursing ; Toxic Stress
    ISSN: 0309-2402
    E-ISSN: 1365-2648
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Language: English
    In: Journal of Pediatric Nursing, August 2012, Vol.27(4), pp.293-293
    Keywords: Medicine ; Nursing
    ISSN: 0882-5963
    E-ISSN: 1532-8449
    Source: ScienceDirect Journals (Elsevier)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Language: English
    In: Journal of Power Sources, 15 September 2017, Vol.362, pp.308-314
    Description: While homoleptic magnesium dialkoxides (MgR , R = alkoxide) have shown promise as precursors for magnesium-ion electrolytes, the effect of ligand steric bulk on the performance of electrolytes based on these compounds is not fully understood. Increasing steric hindrance, studied via R groups with additional phenyl moieties, produces electrolytes with sequentially lower deposition overpotentials (less than −90 mV), higher purity Mg deposits (ca. 100% Mg), and lower overall cell impedances. The two largest alkoxide ligands show consistent cycling behavior and low stripping and plating overpotentials over 200 constant-current plating/stripping cycles. A deep-red visual change and the presence of large solubilized magnesium particulates above 450 nm in size is observed in an electrolyte containing magnesium bis(triphenylmethoxide) and aluminum chloride in contact with an abraded magnesium anode. Further morphological and impedance characterization show that this electrolyte system rapidly activates the magnesium metal anode surface to produce low overpotentials and, as such, is a candidate for further investigation.
    Keywords: Magnesium-Ion Batteries ; Electrodeposition ; Electrolytes ; Alkoxides ; Engineering
    ISSN: 0378-7753
    E-ISSN: 1873-2755
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Language: English
    In: The Journal of biological chemistry, 14 December 2018, Vol.293(50), pp.19250-19262
    Description: Different transcription factors operate together at promoters and enhancers to regulate gene expression. Transcription factors either bind directly to their target DNA or are tethered to it by other proteins. The transcription factor Sp2 serves as a paradigm for indirect genomic binding. It does not require its DNA-binding domain for genomic DNA binding and occupies target promoters independently of whether they contain a cognate DNA-binding motif. Hence, Sp2 is strikingly different from its closely related paralogs Sp1 and Sp3, but how Sp2 recognizes its targets is unknown. Here, we sought to gain more detailed insights into the genomic targeting mechanism of Sp2. ChIP-exo sequencing in mouse embryonic fibroblasts revealed genomic binding of Sp2 to a composite motif where a recognition sequence for TALE homeoproteins and a recognition sequence for the trimeric histone-fold domain protein nuclear transcription factor Y (Nf-y) are separated by 11 bp. We identified a complex consisting of the TALE homeobox protein Prep1, its partner PBX homeobox 1 (Pbx1), and Nf-y as the major partners in Sp2-promoter interactions. We found that the Pbx1:Prep1 complex together with Nf-y recruits Sp2 to co-occupied regulatory elements. In turn, Sp2 potentiates binding of Pbx1:Prep1 and Nf-y. We also found that the Sp-box, a short sequence motif close to the Sp2 N terminus, is crucial for Sp2's cofactor function. Our findings reveal a mechanism by which the DNA binding-independent activity of Sp2 potentiates genomic loading of Pbx1:Prep1 and Nf-y to composite motifs present in many promoters of highly expressed genes.
    Keywords: Pbx1 ; Prep1 ; Tale Homeoproteins ; Chromatin Immunoprecipitation (Chip) ; Gene Regulation ; Nuclear Factor Y (Nf-Y) ; Specificity Protein 1 (Sp1) ; Transcription Factor ; Transcription Factor Sp2 ; Transcription Target Gene
    ISSN: 00219258
    E-ISSN: 1083-351X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Language: English
    In: Journal of Obstetric, Gynecologic & Neonatal Nursing, June 2014, Vol.43, pp.S29-S30
    Description: Purpose for the ProgramAvoiding skin injury is critical to optimizing outcomes in hospitalized patients. High rates of pressure injuries have been reported among patients in pediatric and adult intensive care units (ICUs), but less data on incidence or prevention are available for neonatal ICU patients. The aim of this quality improvement program is to standardize the skin care of patients in our neonatal intensive care unit (NICU). Proposed ChangeAn interdisciplinary team was formed in an acute care, Level IIIC, all referral NICU. This team is responsible for weekly rounds on patients to assess and document skin injuries, collect demographic information, provide education to bedside caregivers, and provide recommendations for skin care. Implementation, Outcomes, and EvaluationThe team underwent standardized training over a 4-week period to detect and stage pressure injuries. Weekly skin rounds began in July 2011. Initial staff resistance to the change in routine was overcome by education via in-services and self-studies on skin injury prevention; this led to a gradual shift in perception and skin rounds are now an accepted routine. There was also tremendous support from administration and nursing, respiratory, and medical leadership, which helped integrate skin rounds into the unit culture.Between July 2011 and August 2013, the skin injury team rounded on a median of 47 patients per week for 100 weeks, for a total of 4,672 patient assessments. The overall incidence of Stage II or greater pressure injuries was 2.79 injuries per 1,000 patient days. Stage II pressure injuries accounted for 64.5% of the injuries assessed. Stage III pressure injuries accounted for 2.8% of the injuries. Suspected deep tissue injuries accounted for 21.5% of the injuries. Injuries that could not be staged accounted for 3.7% of the injuries. Mucosal injuries accounted for 7.5% of the injuries. No Stage IV pressure injuries were detected. The greatest cause of pressure injuries was respiratory devices followed by immobility. The incidence of pressure injuries after the formation of the unit-based skin team increased significantly (from a baseline of 0.49 injuries per 1,000 patient days), which demonstrated an improved detection of injuries with standardized skin rounds. Implications for Nursing PracticeWe have created the largest database of skin injury in the NICU by means of an interdisciplinary team focused on skin injury prevention, education, and regular skin assessments of all infants. This database provides a stable platform upon which to build and measure prevention strategies. This skin care approach could serve as a model for other institutions.
    Keywords: Pressure Ulcer ; Skin Injury ; Neonate ; Medicine ; Nursing
    ISSN: 0884-2175
    E-ISSN: 1552-6909
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Language: English
    In: European Journal of Cancer, July 2016, Vol.61, pp.S67-S67
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/S0959-8049(16)61233-9 Byline: A. Nist, A.M. Krampitz, K. Schlereth, M. Mernberger, M.C. Mo[sz]ner, T. Muley, R. Dammann, T. Stiewe
    Keywords: Medicine
    ISSN: 0959-8049
    E-ISSN: 1879-0852
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    In: 中国物理C:英文版 - Chinese Physica C, 2016, Issue 10, pp.124-125
    Description: The electronic configurations and the ionization energies are from the NIST database, "Ground Levels and Ionization Energies for the Neutral Atoms," W.C. Martin, A. Musgrove, S. Kotochigova, and J.E. Sansonetti, http://www.nist .gov/pml/data/ion_energy. cfm. The electron configuration for, say, iron indicates an argon electronic core (see argon) plus six 3d electrons and two 4s electrons.
    ISSN: 1674-1137
    Source: 维普数据 (Chongqing VIP Information Co.)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Language: English
    In: School Psychology Review, 2008, Vol.37(3), p.294
    Description: This investigation built upon previous studies that compared effectiveness and efficiency among instructional methods. Instructional effectiveness and efficiency were compared among three conditions: an incremental rehearsal, a more challenging ratio of known to unknown interspersal word procedure,...
    Keywords: Reading Difficulties ; Reading Instruction ; Word Recognition ; Instructional Effectiveness ; Teaching Methods ; Instructional Materials ; Grade 1 ; Urban Schools ; Cues ; Drills (Practice) ; Generalization ; Comparative Analysis ; Education ; Psychology
    ISSN: 0279-6015
    E-ISSN: 2372-966X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Language: English
    In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 24 January 2018, Vol.38(4), pp.858-877
    Description: Schwann cell differentiation and myelination depends on chromatin remodeling, histone acetylation, and methylation, which all affect Schwann cell proliferation. We previously reported that the deletion of the POZ (POxvirus and Zinc finger) domain of the transcription factor Miz1 (Myc-interacting zinc finger protein; encoded by ) in mouse Schwann cells (Δ) causes a neuropathy at 90 d after birth [postnatal day (P) 90], with a subsequent spontaneous regeneration. Here we show that RNA sequencing from Δ and control animals at P30 revealed a set of upregulated genes with a strong correlation to cell-cycle regulation. Consistently, a subset of Schwann cells did not exit the cell cycle as observed in control animals and the growth fraction increased over time. From the RNAseq gene list, two direct Miz1 target genes were identified, one of which encodes the histone H3K36 demethylase Kdm8. We show that the expression of is repressed by Miz1 and that its release in Δ cells induces a decrease of H3K36, especially in deregulated cell-cycle-related genes. The linkage between elevated expression, hypomethylation of H3K36 at cell-cycle-relevant genes, and the subsequent re-entering of adult Schwann cells into the cell cycle suggests that the release of repression in the absence of a functional Miz1 is a central issue in the development of the Δ phenotype. The deletion of the Miz1 (Myc-interacting zinc finger protein 1) POZ (POxvirus and Zinc finger) domain in Schwann cells causes a neuropathy. Here we report sustained Schwann cell proliferation caused by an increased expression of the direct Miz1 target gene , encoding a H3K36me2 demethylase. Hence, the demethylation of H3K36 is linked to the pathogenesis of a neuropathy.
    Keywords: Kdm8 ; Miz1 ; Schwann Cell ; Histone Demethylation ; Peripheral Neuropathy ; Proliferation ; Demyelinating Diseases -- Metabolism ; Jumonji Domain-Containing Histone Demethylases -- Metabolism ; Nuclear Proteins -- Metabolism ; Peripheral Nervous System Diseases -- Metabolism ; Protein Inhibitors of Activated Stat -- Metabolism ; Schwann Cells -- Metabolism
    ISSN: 02706474
    E-ISSN: 1529-2401
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages