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  • 1
    UID:
    gbv_1656292114
    Format: Online-Ressource (X, 215 p. 68 illus., 67 illus. in color, online resource)
    ISBN: 9783642548277
    Series Statement: Current Topics in Microbiology and Immunology 377
    Content: This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics; and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers
    Note: Description based upon print version of record , High Dimensional Single Cell Cancer BiologyStudying the Human Immunome: The Complexity of Comprehensive Leukocyte Immunophenotyping -- High-dimensional Analysis of Human CD8+ T Cell Phenotype, Function and Antigen-Specificity -- Mass Cytometry to Decipher the Mechanism of Non-genetic Drug Resistance in Cancer -- A Practical Guide to Multiplexed Mass Cytometry -- Analysis of Protein Interactions in situ by Proximity Ligation Assays -- Cytobank: Providing an Analytics Platform for Community Cytometry Data Analysis and Collaboration -- Computational Analysis of High-Dimensional Flow Cytometric Data for Diagnosis and Discovery -- Shooting Movies of Signaling Network Dynamics with Multiparametric Cytometry -- Hyperspectral Cytometry.
    Additional Edition: ISBN 9783642548260
    Additional Edition: Druckausg. High-dimensional single cell analysis Berlin : Springer, 2014 ISBN 3642548261
    Additional Edition: ISBN 9783642548260
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Cytometrie ; Einzelzellanalyse ; Immuncytochemie ; Bioinformatik ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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