Kooperativer Bibliotheksverbund

Berlin Brandenburg

and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Language
Year
  • 1
    Language: English
    In: PLoS ONE, 01 January 2015, Vol.10(11), p.e0142420
    Description: The evaluation of tools to accurately identify low birth weight (LBW) and/or premature newborns in resource-limited countries is a research priority. We explored the use of foot length, chest circumference, and mid-upper arm circumference (MUAC) measured within 24 h as diagnostic tools for identifying newborns who are LBW, premature, or both; and compared measurements taken at birth with those taken at five days of age.An observational study was undertaken in Hoa Binh Province General Hospital, Vietnam, in ethnic minority newborns. Birth weight, foot length, chest circumference, and MUAC were measured within 24 h of birth and in a subset of 200, were repeated on day five of life. Gestational age was estimated using the New Ballard Score. Receiver Operating Characteristic curves and optimal cut-points (the point with the highest sensitivity and specificity where the sensitivity was at least 0.8) were calculated, for predicting prematurity, LBW, and both. Measurements within 24 h and at five days of life were compared.485 newborns were recruited. Chest circumference and MUAC measured within 24 h of birth were found to be highly predictive of LBW (both yielding area under the curve [AUC] of 0.98, 95% confidence interval [CI] 0.96-0.99), and performed marginally better than foot length (AUC 0.94, 95%CI 0.92-0.96). The optimal cut-points for measurements within 24 h of birth were ≤ 7.4 cm for foot length; ≤ 30.4 cm for chest circumference; and ≤ 9.0 cm for MUAC. There was statistical evidence that anthropometric measurements taken within 24 h of birth were higher than measurements on day five (p〈0.02 for all anthropometric measurements) but the magnitude of these differences was small (at most 2mm).All measurements taken within 24 h of birth were good predictors of LBW, prematurity and both. Differences in measurements taken within 24 h and on day five were not clinically relevant. Further research will ensure that the application of these measures is reliable in community settings.
    Keywords: Sciences (General)
    E-ISSN: 1932-6203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Language: English
    In: The Journal of Allergy and Clinical Immunology, 2011, Vol.127(4), pp.1080-1081
    Description: References4 J Allergy Clin Immunol 123 2009 160 166 Efficacy and safety of 5-grass-pollen sublingual immunotherapy tablets in pediatric allergic rhinoconjunctivitis Wahn U. Tabar A. Kuna P. Halken S. Montagut A. de Beaumont O. 5 Allergy 59 2004 1285 1293 A prospective, randomized, double-blind, placebo-controlled multi-centre study on the efficacy and safety of sublingual immunotherapy (SLIT) in children with seasonal allergic rhinoconjunctivitis to grass pollen Rolinck-Werninghaus C. Wolf H. Liebke C. Baars J.C. Lange J. Kopp M.V. 6 Allergy 59 2004 498 504 Efficacy of sublingual swallow immunotherapy in children with severe grass pollen allergic symptoms: a double-blind placebo-controlled study Bufe A. Ziegler-Kirbach E. Stoeckmann E. Heidemann P. Gehlhar K. Holland-Letz T. 7 J Allergy Clin Immunol 123 2009 167 173 Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy Bufe A. Eberle P. Franke-Beckmann E. Funck J. Kimmig M. Klimek L. 8 J Allergy Clin Immunol 119 2007 892 898 Sublingual immunotherapy with grass pollen is not effective in symptomatic youngsters in primary care Röder E. Berger M.Y. Hop W.C. Bernsen R.M. de Groot H. Gerth van Wijk R. 9 Ann Allergy Asthma Immunol 99 2007 453 461 Sublingual-swallow immunotherapy with standardized 3-grass pollen extract: a double-blind, placebo-controlled study de Blay F. Barnig C. Kanny G. Purohit A. Leynadier F. Tunon de Lara J.M. 10 J Allergy Clin Immunol 120 2007 1338 1345 Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5-grass pollen tablet for seasonal allergic rhinitis Didier A. Malling H.J. Worm M. Horak F. Jäger S. Montagut A. 11 Acta Dermatovenerol Alp Panonica Adriat 16 2007 143 148 Sublingual immunotherapy in pollen-induced seasonal rhinitis and conjunctivitis: a randomized controlled trial Mösges R. Brüning H. Hessler H.J. Götz G. Knaussmann H.G. 12 Ann Allergy Asthma Immunol 100 2008 256 263 Efficacy and safety of specific immunotherapy with a high-dose sublingual grass pollen preparation: a double-blind, placebo-controlled trial Pfaar O. Klimek L. 13 Allergy 64 2009 1394 1401 Efficacy of grass pollen sublingual immunotherapy for three consecutive seasons and after cessation of treatment: the ECRIT study Ott H. Sieber J. Brehler R. Fölster-Holst R. Kapp A. Klimek L. 14 J Allergy Clin Immunol 124 2009 471 477 Early onset of action of a 5-grass-pollen 300-IR sublingual immunotherapy tablet evaluated in an allergen challenge chamber Horak F. Zieglmayer P. Zieglmayer R. Lemell P. Devillier P. Montagut A. 15 J Allergy Clin Immunol 114 2004 831 837 Randomized controlled trial of high-dose sublingual immunotherapy to treat seasonal allergic rhinitis Smith H. White P. Annila I. Poole J. Andre C. Frew A. 16 Allergol Immunopathol (Madr) 23 1995 224 230 Safety and efficacy of sublingual rush immunotherapy with grass allergen extracts: a double blind study Feliziani V. Lattuada G. Parmiani S. Dall’Aglio P.P. 17 Allergol Immunopathol (Madr) 26 1998 234 240 Sublingual immunotherapy with a standardised grass pollen extract; a double-blind placebo-controlled study Hordijk G.J. Antvelink J.B. Luwema R.A. 18 Allergy 54 1999 819 828 Sublingual-swallow immunotherapy (SLIT) with a standardized five-grass-pollen extract (drops and sublingual tablets) versus placebo in seasonal rhinitis Pradalier A. Basset D. Claudel A. Couturier P. Wessel F. Galvain S. André C. 19 Clin Exp Allergy 32 2002 507 514 Grass pollen sublingual immunotherapy for seasonal rhinoconjunctivitis: a randomized controlled trial Lima M.T. Wilson D. Pitkin L. Roberts A. Nouri-Aria K. Jacobson M. 20 J Allergy Clin Immunol 118 2006 434 440 Durham SR. Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhinoconjunctivitis Dahl R. Kapp A. Colombo G. de Monchy J.G. Rak S. Emminger W. 21 Allergy 61 2006 185 190 Specific immunotherapy with SQ standardized grass allergen tablets in asthmatics with rhinoconjunctivitis Dahl R. Stender A. Rak S. 22 J Allergy Clin Immunol 117 2006 802 809 Sublingual immunotherapy with once-daily grass allergen tablets: a randomized controlled trial in seasonal allergic rhinoconjunctivitis Durham S.R. Yang W.H. Pedersen M.R. Johansen N. Rak S.
    Keywords: Medicine
    ISSN: 0091-6749
    E-ISSN: 1097-6825
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Language: English
    In: The Journal of Allergy and Clinical Immunology, 2010, Vol.126(2), pp.395-397
    Description: Polysaccharide antigens, with bound complement C3d, are recognized directly by the B lymphocyte through CD21, which associates with CD19 to enhance and prolong antigen signaling.1 On the basis of a limited number of small studies, the ability to mount T-independent responses is considered to be absent...
    Keywords: Medicine
    ISSN: 0091-6749
    E-ISSN: 1097-6825
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Language: English
    In: The Journal of Allergy and Clinical Immunology, March 2012, Vol.129(3), pp.794-800.e2
    Description: Infections with (pneumococcus) are a cause of significant child mortality. Pneumococcal glycoconjugate vaccines are expensive and provide limited serotype coverage. The 23-valent pneumococcal polysaccharide vaccine (Pneumovax) might provide wider serotype coverage but is reported to be weakly immunogenic in children less than 2 years of age. We have previously reported that Pneumovax administered to healthy 12-month-old Fijian infants elicits significant serotype-specific IgG responses. However, the functional capacity of these responses in 12-month-old infants is not known. We sought to assess the functional, serotype-specific immune response of 12-month-old infants after immunization with Pneumovax. Functional responses of 12-month-old infants were assessed by using the opsonophagocytic and antibody avidity assay against 8 serotypes and 23 serotypes, respectively. Seventy-one percent of infants produced strong opsonophagocytic activity against 4 of 8 serotypes, and 30% produced high-avidity serotype-specific IgG antibodies to 10 of 23 serotypes at 2 weeks after Pneumovax. Responses were protective for most serotypes that cause disease in Western countries, whereas responses to most of the epidemiologically relevant serotypes for developing countries were low. This is the first comprehensive study evaluating the functional antibody response to Pneumovax in 12-month-old infants. Pneumovax induced functional antibody responses to several serotypes causing disease in Western countries but induced poorer responses to serotypes that are responsible for the majority of disease in developing countries. Pneumovax might be of benefit in some populations, but further studies are required before this can be recommended in developing countries.
    Keywords: Pneumococcal Polysaccharide Vaccine ; Antibody ; Opsonophagocytosis ; Avidity ; Function ; Serotype ; Pneumovax ; 23-Valent Pneumococcal Polysaccharide Vaccine (Pneumovax) ; Medicine
    ISSN: 0091-6749
    E-ISSN: 1097-6825
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Language: English
    In: PLoS ONE, 01 January 2017, Vol.12(3), p.e0173407
    Description: OBJECTIVE:To describe the cause-specific morbidity and mortality, and referral patterns of all neonates admitted to a tertiary referral hospital in the northern provinces of Vietnam. DESIGN:A prospective hospital based observational study. SETTING:The Neonatal Department, National Hospital of Pediatrics, Hanoi, Vietnam. PATIENTS:All admissions to the Neonatal Department over a 12 month period. MAIN OUTCOME MEASURES:Cause-specific morbidity and mortality; deaths. RESULTS:There were 5064 admissions with the commonest discharge diagnoses being infection (32%) and prematurity (29%). The case fatality ratio (CFR) was 13.9% (n = 703). Infection (38%), cardio/respiratory disorders (27%), congenital abnormalities (20%) and neurological conditions (10%) were the main causes of death. Of all the deaths, 38% had an admission weight ≥2500g. Higher CFR were associated with lower admission weights. Very few deaths (3%) occurred in the first 24 hours of life. Most referrals and deaths came from Hanoi and neighbouring provincial hospitals, with few from the most distant provinces. Two distant referral provinces had the highest CFR. CONCLUSIONS:The CFR was high and few deaths occurred in neonates 〈24 hours old. The high rates of infection call for an improvement in infection control practices and peripartum antibiotic use at provincial and tertiary level. Understanding provincial hospital capacity and referral pathways is crucial to improving the outcomes at tertiary centres. A quality of care audit tool would enable more targeted interventions and monitoring of health outcomes.
    Keywords: Sciences (General)
    E-ISSN: 1932-6203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Language: English
    In: Journal of Clinical Microbiology, 2010, Vol. 48(10), p.3770
    Description: The use of Mueller-Hinton agar supplemented with citrated human or citrated sheep blood was compared with the use of routinely used Mueller-Hinton agar supplemented with defibrinated sheep blood for antimicrobial susceptibility testing of Streptococcus pneumoniae. The alternate supplements were found to be unsatisfactory, particularly for testing resistant isolates, and therefore are not recommended.
    Keywords: Anti-Bacterial Agents -- Pharmacology ; Culture Media -- Chemistry ; Streptococcus Pneumoniae -- Drug Effects;
    ISSN: 0095-1137
    ISSN: 00951137
    E-ISSN: 1098660X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Language: English
    In: PLoS ONE, 01 January 2015, Vol.10(6), p.e0129199
    Description: Streptococcus pneumonia (the pneumococcus) is the leading vaccine preventable cause of serious infections in infants under 5 years of age. The major correlate of protection for pneumococcal infections is serotype-specific IgG antibody. More recently, antibody-independent mechanisms of protection have also been identified. Preclinical studies have found that IL-17 secreting CD4+ Th17 cells in reducing pneumococcal colonisation. This study assessed IL-17A levels in children from Fiji with high and low pneumococcal carriage density, as measured by quantitative real-time PCR (qPCR). We studied Th17 responses in 54 children who were designated as high density carriers (N=27, 〉8.21x10(5) CFU/ml) or low density carriers (N=27, 〈1.67x10(5) CFU/ml). Blood samples were collected, and isolated peripheral blood mononuclear cells (PBMCs) were stimulated for 6 days. Supernatants were harvested for cytokine analysis by multiplex bead array and/or ELISA. Th17 cytokines assayed included IL-17A, IL-21, IL-22 as well as TNF-α, IL-10, TGF-β, IL-6, IL-23 and IFNγ. Cytokine levels were significantly lower in children with high density pneumococcal carriage compared with children with low density carriage for IL-17A (p=0.002) and IL-23 (p=0.04). There was a trend towards significance for IL-22 (p=0.057) while no difference was observed for the other cytokines. These data provide further support for the role of Th17-mediated protection in humans and suggest that these cytokines may be important in the defence against pneumococcal carriage.
    Keywords: Sciences (General)
    E-ISSN: 1932-6203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Language: English
    In: Journal of Clinical Microbiology, 2010, Vol. 48(11), p.4298
    Description: Multilocus sequence typing (MLST) was applied to all unique serotype 6C and 6D isolates and a random selection of serotype 6B and 6A isolates from nasopharyngeal swabs from Fijian children enrolled in a recent vaccine trial. The results suggest that Fijian serotype 6D has arisen independently from both serotypes 6A/C and 6B.
    Keywords: Medicine ; Biology;
    ISSN: 0095-1137
    ISSN: 00951137
    E-ISSN: 1098660X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
  • 10
    Language: English
    In: Bulletin of the World Health Organization, 2003, Vol.81(5), pp.367-72
    Description: Antipyretics, including acetaminophen (paracetamol), are prescribed commonly in children with pyrexia, despite minimal evidence of a clinical benefit. A literature review was performed by searching Medline and the Cochrane databases for research papers on the efficacy of paracetamol in febrile illnesses in children and adverse outcomes related to the use of paracetamol. No studies showed any clear benefit for the use of paracetamol in therapeutic doses in febrile children with viral or bacterial infections or with malaria. Some studies suggested that fever may have a beneficial role in infection, although no definitive prospective studies in children have been done to prove this. The use of paracetamol in therapeutic doses generally is safe, although hepatotoxicity has occurred with recommended dosages in children. In developing countries where malnutrition is common, data on the safety of paracetamol are lacking. The cost of paracetamol for poor families is substantial. No evidence shows that it is beneficial to treat febrile children with paracetamol. Treatment should be given only to children who are in obvious discomfort and those with conditions known to be painful. The role of paracetamol in children with severe malaria or sepsis and in malnourished, febrile children needs to be clarified.
    Keywords: Acetaminophen -- Therapeutic Use ; Analgesics, Non-Narcotic -- Therapeutic Use ; Fever -- Drug Therapy
    ISSN: 0042-9686
    E-ISSN: 15640604
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages