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Berlin Brandenburg

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  • 1
    Language: English
    In: Science (New York, N.Y.), 22 April 2011, Vol.332(6028), pp.426-7
    Description: A common basis of human mortality is the heart, arising from morphogenetic defects of the organ at birth as well as from the chronic ravages of hypertension and coronary artery disease later in life . A key pathological mechanism is muscle cell death, mitigated by only a scant capacity for muscle cell renewal. Rescuing cardiac muscle cell number might underlie therapeutic strategies, such as the use of antagonists of muscle cell death, stem cell grafting (now pursued in clinical trials), and activating self-repair by dormant cardiac stem cells in the heart . However, the genetic networks that control cardiac muscle cell number are not completely understood. On page 458 of this issue, Heallen et al. provide insights into a signaling pathway that represses the cardiac cell division cycle in mice, and show that impairing this pathway can unleash cardiac cell proliferation.
    Keywords: Cell Proliferation ; Signal Transduction ; Myocytes, Cardiac -- Cytology ; Protein-Serine-Threonine Kinases -- Metabolism
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 2
    In: Nature, 2014, Vol.508(7497), p.465
    Keywords: Temperature ; Seawater -- Analysis;
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 3
    In: Nature, 2010, Vol.464(7292), p.1125
    Description: Abstract not available.
    Keywords: Public Policy and Climate ; Climatology (551.58);
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 4
    Language: English
    In: Nature, April 24, 2014, Vol.508(7497), p.465(2)
    Description: On page 477 of this issue, Rohling et al.1 present a convincing approach for calculating sea-level fluctuations over the past 5 million years (Myr). Their method depends on variations in the oxygen-isotope composition of shells produced by unicellular organisms called planktonic foraminifera (Fig. 1)....
    Keywords: Sea Level – Natural History ; Seawater – Natural History ; Oxygen Isotopes – Chemical Properties ; Oxygen Isotopes – Natural History
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 5
    Language: English
    In: Nature, May 16, 2013, Vol.497(7449), p.311(2)
    Keywords: Charities – Rites, Ceremonies and Celebrations
    ISSN: 0028-0836
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  • 6
    In: Journal of Marriage and Family, August 2011, Vol.73(4), pp.845-860
    Description: I examine the contested finding that men and women engage in gender performance through housework. Prior scholarship has found a curvilinear association between earnings share and housework that has been interpreted as evidence of gender performance. I reexamine these findings by conducting the first such analysis to use high‐quality time diary data for a U.S. sample in the contemporary period. Drawing on data on 11,868 married women and 10,770 married men in the American Time Use Survey (2003–2007), I find no evidence that married men “do gender” through housework. I do, however, find strong evidence of gender performance among women as evidenced by a curvilinear association between earnings share and women's housework time.
    Keywords: Family And Work ; Gender ; Housework/Division Of Labor
    ISSN: 0022-2445
    E-ISSN: 1741-3737
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  • 7
    Article
    Article
    Language: English
    In: Science, 08/15/2014, Vol.345(6198), pp.737-738
    Description: ![Figure][1] Henry David Thoreau spent much of 23 August 1853 walking the environs of Concord, Massachusetts. He noted the advancing of summer to autumn in no fewer than 27 species of plants and six species of animals while exhorting “Live in each season as it passes; breathe the air, drink
    Keywords: Sciences (General) ; Biology;
    ISSN: 0036-8075
    E-ISSN: 1095-9203
    Source: American Association for the Advancement of Science (via CrossRef)
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  • 8
    Language: English
    In: Journal of the American Chemical Society, 01 February 2012, Vol.134(4), pp.2407-13
    Description: We present evidence that specific material recognition by small peptides is governed by local solvent density variations at solid/liquid interfaces, sensed by the side-chain residues with atomic-scale precision. In particular, we unveil the origin of the selectivity of the binding motif RKLPDA for Ti over Si using a combination of metadynamics and steered molecular dynamics simulations, obtaining adsorption free energies and adhesion forces in quantitative agreement with corresponding experiments. For an accurate description, we employ realistic models of the natively oxidized surfaces which go beyond the commonly used perfect crystal surfaces. These results have profound implications for nanotechnology and materials science applications, offering a previously missing structure-function relationship for the rational design of materials-selective peptide sequences.
    Keywords: Peptides -- Chemistry
    ISSN: 00027863
    E-ISSN: 1520-5126
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  • 9
    Language: English
    In: American Journal of Sociology, 01 January 2012, Vol.117(4), pp.1029-1072
    Description: This article takes a new approach to gender and housework by identifying a new measure of gender deviancework in gender-atypical occupationsand by arguing that men who do womens work and women who do mens work in the labor market may seek to neutralize their gender deviance by doing male- and female-typed work at home. Analysis of data from the National Survey of Families and Households and the 20037 waves of the American Time Use Survey shows that men who do womens work in the market spend more time on male-typed housework relative to men in gender-balanced occupations and their wives spend more time on female-typed housework. Women in gender-atypical occupations also do more female-typed housework than women in gender-balanced occupations. The article provides clearer evidence about the important ways in which cultural conceptions of gender shape and are shaped by economic processes.
    Keywords: Sex ; Sex Roles ; Housework ; Occupations ; Gender ; Deviance ; Domestic Workers ; Labour Market ; Surveys ; U.S.A. ; Sociology;
    ISSN: 00029602
    E-ISSN: 15375390
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  • 10
    Language: English
    In: Proceedings of the National Academy of Sciences of the United States, Oct 16, 2012, Vol.109(42), p.17174(6)
    Description: Flies display transient social interactions in groups. However, whether fly-fly interactions are stochastic or structured remains unknown. We hypothesized that groups of flies exhibit patterns of social dynamics that would manifest as nonrandom social interaction networks. To test this, we applied a machine vision system to track the position and orientation of flies in an arena and designed a classifier to detect interactions between pairs of flies. We show that the vinegar fly, Drosophila melanogaster, forms nonrandom social interaction networks, distinct from virtual network controls (constructed from the intersections of individual locomotor trajectories). In addition, the formation of interaction networks depends on chemosensory cues. Gustatory mutants form networks that cannot be distinguished from their virtual network controls. Olfactory mutants form networks that are greatly disrupted compared with control flies. Different wild-type strains form social interaction networks with quantitatively different properties, suggesting that the genes that influence this network phenotype vary across and within wild-type populations. We have established a paradigm for studying social behaviors at a group level in Drosophila and expect that a genetic dissection of this phenomenon will identify conserved molecular mechanisms of social organization in other species. social network | emergent phenotypes | complex systems doi/10.1073/pnas.1121252109
    Keywords: Drosophila -- Social Aspects ; Drosophila -- Behavior ; Animal Behavior -- Social Aspects ; Biomathematics -- Research
    ISSN: 0027-8424
    Source: Cengage Learning, Inc.
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