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  • 1
    Online Resource
    Online Resource
    Ancient DNA : Methods and Protocols (2012)
    Totowa, NJ :Humana Press :
    Details
    UID:
    almahu_9949251553402882
    Format: 1 online resource (XII, 247p. 26 illus., 12 illus. in color.)
    Edition: 1st ed. 2012.
    ISBN: 1-61779-516-X
    Series Statement: Methods in Molecular Biology, 840
    Content: Research into ancient DNA began more than 25 years ago with the publication of short mitochondrial DNA sequence fragments from the quagga, an extinct relative of the zebra. Ancient DNA research really gained momentum following the invention of PCR, which allowed millions of copies to be made of the few remaining DNA molecules preserved in fossils and museum specimens.  In Ancient DNA: Methods and Protocols expert researchers in the field describe many of the protocols that are now commonly used to study ancient DNA. These include instructions for setting up an ancient DNA laboratory, extraction protocols for a wide range of different substrates, details of laboratory techniques including PCR and NGS library preparation, and suggestions for appropriate analytical approaches to make sense of the sequences obtained. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Ancient DNA: Methods and Protocols seeks to aid scientists in the further study of ancient DNA and the methodological approaches in ancient research.
    Note: Bibliographic Level Mode of Issuance: Monograph , Setting up an ancient DNA laboratory / Tara L. Fulton -- A phenol-chloroform protocol for extracting DNA from ancient samples / Ross Barnett and Greger Larson -- DNA extraction of ancient animal hard tissue samples via adsorption to silica particles / Nadin Rohland -- Case study : recovery of ancient nuclear DNA from toe pads of the extinct passenger pigeon / Tara L. Fulton, Stephen M. Wagner, and Beth Shapiro -- Extraction of DNA from paleofeces / Melanie Kuch and Hendrik Poinar -- DNA extraction from keratin and chitin / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient sloth DNA recovered from hairs preserved in paleofeces / Andrew A. Clack, Ross D.E. MacPhee, and Hendrik N. Poinar -- Ancient DNA extraction from soils and sediments / James Haile -- DNA extraction from fossil eggshell / Charlotte L. Oskam and Michael Bunce -- Ancient DNA extraction from plants / Logan Kistler -- DNA extraction from formalin-fixed material / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient DNA recovered from Pleistocene-age remains of a Florida armadillo / Brandon Letts and Beth Shapiro -- Nondestructive DNA extraction from museum specimens / Michael Hofreiter -- Case study : using a nondestructive DNA extraction method to generate mtDNA sequences from historical chimpanzee specimens / Elmira Mohandesan, Stefan Prost, and Michael Hofreiter -- PCR amplification, cloning, and sequencing of ancient DNA / Tara L. Fulton and Mathias Stiller -- Quantitative real-time PCR in aDNA research / Michael Bunce, Charlotte L. Oskam, and Morten E. Allentoft -- Multiplex PCR amplification of ancient DNA / Mathias Stiller and Tara L. Fulton -- Preparation of next-generation sequencing libraries from damaged DNA / Adrian W. Briggs and Patricia Heyn -- Generating barcoded libraries for multiplex high-throughput sequencing / Michael Knapp, Mathias Stiller, and Matthias Meyer -- Case study : targeted high-throughput sequencing of mitochondrial genomes from extinct cave bears via direct multiplex PCR sequencing (DMPS) / Mathias Stiller -- Target enrichment via DNA hybridization capture / Susanne Horn -- Case study : enrichment of ancient mitochondrial DNA by hybridization capture / Susanne Horn -- Analysis of high-throughput ancient DNA sequencing data / Martin Kircher -- Phylogenetic analysis of ancient DNA using BEAST / Simon Y.W. Ho. , English
    Additional Edition: ISBN 1-61779-515-1
    Language: English
    Subjects: Biology
    RVK:
    WC 4150
    Keywords: Aufsatzsammlung. ; Aufsatzsammlung. ; Aufsatzsammlung. ; Aufsatzsammlung.
    DOI: 10.1007/978-1-61779-516-9
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  • 2
    Online Resource
    Online Resource
    Ancient DNA : Methods and Protocols (2019)
    New York, NY :Springer New York :
    Details
    UID:
    almahu_9949251678102882
    Format: 1 online resource (X, 216 p. 15 illus., 5 illus. in color.)
    Edition: 2nd ed. 2019.
    ISBN: 1-4939-9176-0
    Series Statement: Methods in Molecular Biology, 1963
    Content: This fully updated second edition explores protocols that address the most challenging aspects of experimental work in ancient DNA, such as preparing ancient samples for DNA extraction, the DNA extraction itself, and transforming extracted ancient DNA molecules for sequencing library preparation. The volume also examines the analysis of high-throughput sequencing data recovered from ancient specimens, which, because of the degraded nature of ancient DNA and common co-extraction of contaminant DNA, has challenges that are unique compared to data recovered from modern specimens.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Ancient DNA: Methods and Protocols, Second Edition aims to serve both experts and beginners by presenting protocols in a manner that makes them easily accessible for everyday use in the lab.
    Note: Setting Up an Ancient DNA Laboratory -- Pretreatment: Removing DNA Contamination from Ancient Bones and Teeth Using Sodium Hypochlorite and Phosphate -- Pretreatment: Improving Endogenous Ancient DNA Yields Using a Simple Enzymatic Pre-Digestion Step -- Extraction of Highly Degraded DNA from Ancient Bones and Teeth -- Sampling and Extraction of Ancient DNA from Sediments -- Extraction of Ancient DNA from Plant Remains -- DNA Extraction from Keratin and Chitin -- Double-Stranded Library Preparation for Ancient and Other Degraded Samples -- A Method for Single-Stranded Ancient DNA Library Preparation -- Sequencing Library Preparation from Degraded Samples for Non-Illumina Sequencing Platforms -- Whole-Genome Capture of Ancient DNA Using Homemade Baits -- Generating RNA Baits for Capture-Based Enrichment -- Hybridization Capture of Ancient DNA Using RNA Baits -- Application of Solid-State Capture for the Retrieval of Small-to-Medium Sized Target Loci from Ancient DNA -- Targeted PCR Amplification and Multiplex Sequencing of Ancient DNA for SNP Analysis -- Targeted Amplification and Sequencing of Ancient Environmental and Sedimentary DNA -- Authentication and Assessment of Contamination in Ancient DNA -- Assembly of Ancient Mitochondrial Genomes without a Closely Related Reference Sequence.
    Additional Edition: ISBN 1-4939-9175-2
    Language: English
    DOI: 10.1007/978-1-4939-9176-1
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  • 3
    Book
    Book
    Ancient DNA : methods and protocols (2019)
    New York :Humana Press,
    Details
    UID:
    almahu_BV046108949
    Format: X, 216 Seiten : , Illustrationen.
    Edition: Second edition
    ISBN: 978-1-4939-9175-4 , 978-1-4939-9176-1
    Series Statement: Methods in molecular biology 1963
    Additional Edition: Erscheint auch als Online-Ausgabe Shapiro, Beth Ancient DNA New York : Humana Press, [2019] ISBN 978-1-4939-9176-1
    Language: English
    Subjects: Biology
    RVK:
    WD 5360
    RVK:
    WC 4150
    Keywords: Fossil ; Genanalyse ; Paläobiologie ; DNS ; Methode ; Fossil ; DNS ; Methode ; Aufsatzsammlung
    Author information: Paijmans, Johanna L. A.
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  • 4
    Book
    Book
    Selection of library materials in applied and interdisciplinary fields / (1987)
    Chicago u.a. :American Libr. Assoc.,
    Details
    UID:
    almafu_BV000659030
    Format: XII, 287 S.
    ISBN: 0-8389-0466-1
    Note: Forts. von: Selection of library materials in the humanities, social sciences, and sciences
    Subjects: General works
    RVK:
    AN 71000
    Keywords: Interdisziplinäre Forschung ; Bibliothek ; Buchauswahl ; Angewandte Forschung ; Bibliothek ; Buchauswahl ; Bibliothek ; Erwerbung
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  • 5
    Book
    Book
    Life as we made it : how 50,000 years of human innovation refined - and redefined - nature (2021)
    New York : Basic Books
    Details
    UID:
    gbv_1785873253
    Format: vii, 340 Seiten , 24 cm
    Edition: First edition
    ISBN: 9781541644182
    Content: Prologue: Providence -- Bone mining -- Origin story -- Blitzkrieg -- Lactase persistence -- Lake cow bacon -- Polled -- Intended consequences -- Turkish delight.
    Content: "Humans seem to be destroying nature with incessant fiddling. We can use viruses to insert genes for pesticide resistance into plants, or to make the flesh of goldfish glow. We can turn bacteria into factories for millions of molecules, from vitamin A and insulin to diesel fuel. And this year's Nobel Prize went to the inventors of tool called CRISPR, which lets us edit genomes almost as easily as we can edit the text in a computer document. The potential for harm can seem both enormous and inevitable. In Life as We Made It, evolutionary biologist Beth Shapiro argues that our fears of new technologies aren't just mistaken, but they miss the big picture about human history: we've been remaking nature for as long as we've been around. As Shapiro shows, the molecular tools of biotechnology are just the latest in a long line of innovations stretching back to the extra food and warm fires that first brought wolves into the human fold, turning them into devoted dogs. Perhaps more importantly, Shapiro offers a new understanding of the evolution of our species and those that surround us. We might think of evolution as a process bigger than humans (and everything else). To the contrary, Shapiro argues that we have always been active participants in it, driving it both inadvertently and intentionally with our remarkable capacity for technological innovation. Shapiro shows that with each innovation and every plant and animal we touched, we not only shaped our own diets, genes, and social structures but we reset the course of evolution, both theirs and ours. Indeed, although we think of only modern technology as capable of gene editing, she shows that even the first stone tools could edit DNA, simply by changing the world in which all life lives. Recasting the history of biology and technology alike, Life as We Made It shows that the history of our species is essentially and inevitably a story of us meddling with nature. And that ultimately, our species' fate depends on how we do it in the future"--
    Note: Includes bibliographical references and index
    Additional Edition: ISBN 9781541644151
    Language: English
    Keywords: Anthropogener Einfluss ; Landschaftszerstörung ; Biotechnologie
    URL: Inhaltsverzeichnis
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  • 6
    Book
    Book
    Ancient DNA : methods and protocols (2012)
    New York, NY [u.a.] : Humana Press
    Details
    UID:
    kobvindex_ZLB15442973
    Format: XII, 247 Seiten , Ill., graph. Darst.
    ISBN: 9781617795152
    Series Statement: Springer protocols handbooks 840
    Language: English
    Keywords: Pleistozän ; DNS ; Genetischer Fingerabdruck ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
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  • 7
    Article
    Article
    The FACES project : an academic-community partnership to improve end-of-life care for families (2007)
    Show associated volumes
    Details
    UID:
    gbv_54976903X
    ISSN: 0163-4372
    In: Journal of gerontological social work, New York, NY : Haworth, 1978, 50(2007), 1/2, Seite 7-20, 0163-4372
    In: volume:50
    In: year:2007
    In: number:1/2
    In: pages:7-20
    Language: English
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  • 8
    Book
    Book
    How to clone a mammoth : the science of de-extinction (2015)
    Princeton, NJ [u.a.] :Princeton Univ Press,
    Details
    UID:
    almahu_BV042617037
    Format: XII, 220 S. : , Ill.
    ISBN: 978-0-691-15705-4
    Additional Edition: Erscheint auch als Online-Ausgabe How to Clone a Mammoth
    Language: English
    Subjects: Biology
    RVK:
    WG 3450
    Keywords: Ausgestorbene Tiere ; Genklonierung
    URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028049820&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
    URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028049820&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
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  • 9
    Book
    Book
    Ancient DNA : methods and protocols (2012)
    New York, NY [u.a.] : Humana Press
    Details
    UID:
    b3kat_BV039801150
    Format: XII, 247 S. , graph. Darst.
    ISBN: 9781617795152 , 9781617795169
    Series Statement: Methods in molecular biology 840
    Language: English
    Subjects: Biology
    RVK:
    WC 4150
    RVK:
    WD 5360
    Keywords: Paläobiologie ; DNS ; Methode ; Fossil ; DNS ; Methode ; Fossil ; Genanalyse ; Aufsatzsammlung
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  • 10
    Online Resource
    Online Resource
    How to Clone a Mammoth : The Science of De-Extinction (2015)
    Princeton, N.J. :Princeton University Press,
    Details
    UID:
    edocfu_9959051637402883
    Format: 1 online resource(240 p.) : , illustrations.
    Edition: Course Book.
    Edition: Electronic reproduction. Princeton, N.J. : Princeton University Press, 2015. Mode of access: World Wide Web.
    Edition: System requirements: Web browser.
    Edition: Access may be restricted to users at subscribing institutions.
    ISBN: 9781400865482
    Content: Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Pääbo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal? Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem. Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.
    Note: Frontmatter -- , CONTENTS -- , PROLOGUE -- , Chapter 1. Reversing Extinction -- , Chapter 2. Select a Species -- , Chapter 3. Find a Well-Preserved Specimen -- , Chapter 4. Create a Clone -- , Chapter 5. Breed Them Back -- , Chapter 6. Reconstruct the Genome -- , Chapter 7. Reconstruct Part of the Genome -- , Chapter 8. Now Create a Clone -- , Chapter 9. Make More of Them -- , Chapter 10. Set Them Free -- , Chapter 11. Should We? -- , ACKNOWLEDGMENTS -- , NOTES -- , INDEX , In English.
    Language: English
    DOI: 10.1515/9781400865482
    URL: https://doi.org/10.1515/9781400865482
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