UID:
kobvindex_HPB1285779364
Format:
1 online resource (590 p.).
ISBN:
1839162899
,
9781839162893
Series Statement:
ISSN
Content:
Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and will help the end users understand the practicalities of using different instruments for different ion mobility purposes.
Note:
Description based upon print version of record.
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4.2 TWIMS: Design and Operation.
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Intro -- Half title -- Title -- Copyright -- Preface -- Contents -- Chapter 1 Ion Mobility-Mass Spectrometry: an Overview -- 1.1 What is Ion Mobility Spectrometry? -- 1.1.1 Spectrometry -- 1.1.2 Ion Mobility -- 1.2 What is Ion Mobility Spectrometry Used For? -- 1.2.1 An Additional Method of Separation Coupled to Mass Spectrometry -- 1.2.2 To Identify Compounds Based on Their Ion Mobility -- 1.3 Key Definitions and Equations for Ion Mobility Spectrometry -- 1.3.1 What is Being Measured: the Mobility of an Ion in a Gas -- 1.3.2 Units of Ion Mobility -- 1.3.3 Reduced Ion Mobility (K0)
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1.3.4 Collision Cross-sections -- 1.4 How is Ion Mobility Measured? -- 1.4.1 Drift Tube IMS (DTIMS) -- 1.4.2 Traveling Wave IMS (TWIMS) -- 1.4.3 Differential Mobility Analyzer (DMA) -- 1.4.4 Field-asymmetric Waveform IMS (FAIMS) -- 1.4.5 Trapped Ion Mobility Spectrometry (TIMS) -- 1.5 Comparison Between Ion Mobility Measurement Techniques -- 1.5.1 Spatial and/or Temporal Separation -- 1.5.2 Linear vs. Non-linear Methods -- 1.5.3 Requirement for Calibration -- 1.5.4 IM-MS Hyphenation -- 1.6 Conclusion and Outlook -- Acknowledgements -- References
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Chapter 2 Calculation of Momentum Transfer Cross-sections -- 2.1 Introduction -- 2.2 The Momentum Transfer Cross-section -- 2.2.1 Momentum Transfer Cross-section, Defined -- 2.2.2 Deflection Function -- 2.3 Momentum Transfer Cross-sections and the Interaction Potential -- 2.3.1 Classical Deflection Function -- 2.3.2 Hard-sphere Interaction Potential -- 2.3.3 Attractive and Repulsive Interaction Potentials -- 2.3.4 Influence of the Size or Molecular Weight of the Analyte -- 2.3.5 Influence of the Ion Shape or Conformation -- 2.3.6 Influence of the Ion Charge Distribution
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2.4 Estimating Momentum Transfer Cross-sections for Molecular Models -- 2.4.1 Overview of the Methods -- 2.4.2 Projection Superposition Approximation (PSA) -- 2.5 Outlook and Concluding Remarks -- Acknowledgements -- References -- Chapter 3 Fundamentals of Uniform-field Drift Tube Ion Mobility and Collision Cross Section -- 3.1 Uniform-field Drift Tube Ion Mobility-Mass Spectrometry Introduction -- 3.2 Brief History of DTIMS Developments -- 3.3 Uniform-field Drift Tube Ion Mobility Separations -- 3.3.1 Ion Mobility -- 3.3.2 Ion Arrival Time, Resolving Power and Separation Efficiency
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3.4 Drift Tube Ion Mobility Instrumental Design -- 3.4.1 Atmospheric and Reduced Pressure Systems -- 3.4.2 Combining Ion Mobility and Time-of-flight Measurements -- 3.5 The Fundamental Low-field Ion Mobility Equation -- the Basis for Collision Cross Section Determination -- 3.5.1 Defining Collision Cross Section -- 3.5.2 Determining CCS from First Principles -- the Stepped-field Method -- 3.5.3 Achieving CCS Measurements via Calibration (Single Field) -- 3.6 Conclusions -- Acknowledgements -- References -- Chapter 4 Travelling Wave Ion Mobility Separation: Basics and Calibration -- 4.1 Introduction
Additional Edition:
Print version: Ashcroft, Alison E Ion Mobility-Mass Spectrometry Cambridge : Royal Society of Chemistry,c2021 9781839161667
Language:
English
Keywords:
Electronic books.
URL:
http://public.eblib.com/choice/PublicFullRecord.aspx?p=6804779
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