Format:
Online-Ressource (IX, 176 p)
,
online resource
Edition:
Springer eBook Collection. Biomedical and Life Sciences
ISBN:
9783709160169
Content:
Progress in basic and clinical immunology within the last two decades has provided profound insight into the immune system and its role in preventing endogenous and exogenous damage. In contrast, disbalances within this system can result in autoimmune disorders which may affect diverse organs and result in distinct clinical pictures. In many of these, however, the individual etiopathogenetic mechanisms are poorly understood and even more their clinical symptoms are hard to treat. The book offers insight into basic mechanisms of autoimmune disorders. It includes neurological, gastrointestinal, ophthalmological and skin diseases as well as current and future therapeutic options including immunomodulatory drugs and different vaccination strategies. By addressing diverse organ systems, both singular and shared features are elaborated. Thus an exchange of ideas is intended across research on single organ systems within a truly interdisciplinary setting
Note:
ForwordPreface -- Definitive T Cell epitope mapping for human disease: gluten challenge in coeliac disease identifies dominant transglutaminase-deamidated T Cell epitope -- On the extrapolation from animal models to human disease for the design of immunotherapy in autoimmune diabetes -- Use of olfactory ensheathing cells as candidates for transplant-mediated repair of central nervous system lesions -- Advances in understanding and use of autoantibodies as markers of diseases -- Leflunomide therapy for autoimmune diseases -- Immunotherapy for ocular inflammatory disease -- Advances in immunosuppressive treatment of juvenile idiopathic arthritis -- Significance of gamma-delta T lymphocytes in autoimmune diseases -- Treatment of autoimmune diseases by target DNA vaccines encoding pro-inflammatory mediators -- Immunosuppressive treatment of rheumatic diseases during pregnancy -- Persistence of maternal and fetal cells in autoimmune diseases -- Therapeutic aspects of autoimmune diseases of the skin -- Long term effects of T Cell vaccination in multiple sclerosis -- Plasmid-mediated delivery of antigens or biological response modifiers as means to suppress autoimmunity -- Intravenous immunoglobulins for the treatment of childhood autoimmune diseases.
Additional Edition:
ISBN 9783709172889
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783709172889
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783211837726
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783709160176
Language:
English
DOI:
10.1007/978-3-7091-6016-9
URL:
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