UID:
almahu_9949383628002882
Format:
1 online resource (xiv, 270 pages)
Edition:
Second edition.
ISBN:
9780429341441
,
042934144X
,
9781000680898
,
1000680894
,
9781000681161
,
1000681165
,
9781000681437
,
1000681432
Content:
The first edition of this book covered the basic treatment of the enzyme reaction using the overall reaction kinetics and stopped-flow method, the general properties of protein and cofactors, the control of enzyme reaction, and the preparation of enzyme protein. These topics are the basis of enzyme research and thus suitable for the beginner in the field. The second edition presents the cofactors produced via the post-translational modification of the enzyme's active site. These cofactors expand the function of enzymes and open a new research field. The carbonyl reagent phenylhydrazine and related compounds have been useful in finding some of the newly discovered cofactors and thus have been discussed in this edition. The topic of the control of enzyme activity through the channel of substrates and products in polyfunctional enzymes has also been expanded in this book.
Content:
For a long time, enzymes have been studied by measuring their activity, which has led to the advancement of 'enzyme kinetics'. In recent years, the mechanism of enzyme reaction has been explained in detail on the basis of the 3D structure. Genetic engineering and the 3D structural analysis of enzymes contribute to these advancements in enzymology. This book starts with an introduction to various enzymes to show how interesting enzymes are, which is followed by historical kinetic studies on enzymes and the overall and rapid-reaction kinetics. The subsequent topics describe the basics of protein structure, the control of enzyme activity, and the purification of enzymes.
Note:
1. Overall Reaction Kinetics 2. Facors that Affect Enzyme Activity 3. Effect of pH, Temperature, High pressure on the Enzymatic Activity 4. Measurement of Individual Rate Constants 5. Structure of Protein 6. Cofactors 7. Search of Active site 8. Control of Enzyme Activity 9. Channeling of Substrates and Products10. Preparation of Enzyme 11. A Case Study: L-Phenylalanine Oxidase (Deaminating and Decarboxylating)
Additional Edition:
Print version: Suzuki, Haruo. How Enzymes Work : From Structure to Function. Milton : Pan Stanford Publishing, ©2019 ISBN 9789814800662
Language:
English
Keywords:
Electronic books.
;
Electronic books.
URL:
https://www.taylorfrancis.com/books/9780429341441
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