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  • 1
    Language: English
    In: Nature, 28 September 2017, Vol.549(7673), pp.460-461
    Description: Efforts to treat brain tumours by targeting cancer cells have had only modest clinical success. It emerges that targeting a protein secreted from neurons adjacent to the tumour might be a useful alternative approach.
    Keywords: Glioma
    ISSN: 00280836
    E-ISSN: 1476-4687
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  • 2
    Language: English
    In: Cancer Research, 04/15/2012, Vol.72(8 Supplement), pp.SY25-02-SY25-02
    ISSN: 0008-5472
    E-ISSN: 1538-7445
    Source: CrossRef
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  • 3
    In: Nature, 2017
    Keywords: Gliomas -- Care And Treatment ; Gliomas -- Development And Progression ; Cellular Signal Transduction -- Health Aspects;
    ISSN: 0028-0836
    E-ISSN: 1476-4687
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  • 4
    Language: English
    In: Criminal Justice and Behavior, May 2011, Vol.38(5), pp.471-491
    Description: This study examines the extent to which cognitive ability, the Big Five factor personality dimensions, and emotional intelligence are related to training and job performance of U.S. federal criminal investigators. Training performance measures were collected during a 17-week training program. Job performance measures were collected 1 year after the investigators completed the training program. Conscientiousness was modestly related to training performance. Cognitive ability and emotional intelligence were positively correlated with job performance. Neuroticism was negatively correlated with job performance. The relative benefits of using emotional intelligence and the five-factor model to select law enforcement agents are discussed.
    Keywords: Cognitive Ability ; Emotional Intelligence ; Big Five ; Criminal Investigators ; Social Welfare & Social Work ; Psychology
    ISSN: 0093-8548
    E-ISSN: 1552-3594
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  • 5
    Language: English
    In: Journal of the American College of Cardiology, 29 November 2016, Vol.68(21), pp.2308-2310
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jacc.2016.09.922 Byline: Michael D. Taylor, Jeffrey A. Towbin Abstract: Display Omitted Author Affiliation: (a) Division of Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (b) Division of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee (c) Division of Cardiology, St. Jude Children's Research Hospital, Memphis, Tennessee (d) The Heart Institute, Le Bonheur Children's Hospital, Memphis, Tennessee Article Note: (footnote) Both authors have reported that they have no relationships relevant to the contents of this paper to disclose.
    Keywords: Atrial Fibrillation ; Cardiomyopathy ; Genetic ; Inherited ; Laminopathy ; Neuromuscular ; Medicine
    ISSN: 0735-1097
    E-ISSN: 1558-3597
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  • 6
    Language: English
    In: Cancer Research, 12/01/2015, Vol.75(23 Supplement), pp.PR03-PR03
    ISSN: 0008-5472
    E-ISSN: 1538-7445
    Source: CrossRef
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  • 7
    Language: English
    In: Nature medicine, May 2018, Vol.24(5), pp.534-535
    Description: Anti-GD2 chimeric antigen receptor (CAR)-modified T cells may be a new and innovative approach for the treatment of pediatric H3-K27M-mutant diffuse midline gliomas.
    Keywords: Children ; Lymphocytes T ; Lymphocytes;
    ISSN: 10788956
    E-ISSN: 1546-170X
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  • 8
    In: Nature Genetics, 2015, Vol.47(8), p.851
    Description: Relapsed neuroblastoma is common, frequently lethal and poorly studied and poses a major treatment challenge. Two new studies shed light on the genomic landscape of recurrent neuroblastoma and demonstrate profound differences between the disease at diagnosis and relapse.
    Keywords: Genomics ; Neoplasm Recurrence, Local -- Genetics ; Neuroblastoma -- Genetics;
    ISSN: 1061-4036
    E-ISSN: 15461718
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  • 9
    Language: English
    In: Cancer Research, 04/15/2012, Vol.72(8 Supplement), pp.1445-1445
    ISSN: 0008-5472
    E-ISSN: 1538-7445
    Source: CrossRef
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  • 10
    Language: English
    In: Journal of Biomechanics, 16 November 2018, Vol.81, pp.58-67
    Description: Congenital pulmonary artery (PA) stenosis is often associated with abnormal PA hemodynamics including increased pressure drop (Δ ) and reduced asymmetric flow ( ), which may result in right ventricular dysfunction. We propose functional diagnostic parameters, (CDP), ( ), and ( ) to characterize pulmonary hemodynamics, and evaluate their efficacy in delineating stenosis severity using experiments. Subject-specific test sections including the main PA (MPA) bifurcating into left and right PAs (LPA, RPA) with a discrete LPA stenosis were manufactured from cross-sectional imaging and 3D printing. Three clinically-relevant stenosis severities, 90% area stenosis (AS), 80% AS, and 70% AS, were evaluated at different cardiac outputs (COs). A benchtop flow loop simulating pulmonary hemodynamics was used to measure and Δ within the test sections. The experimental Δ - characteristics along with clinical data were used to obtain pathophysiologic conditions and compute the diagnostic parameters. The pathophysiologic decreased as the stenosis severity increased at a fixed CO. CDP , (absolute), and (absolute) increased with an increase in LPA stenosis severity at a fixed CO. Importantly, CDP and had reduced variability with CO, and distinct values for each LPA stenosis severity. Under variable CO, a) CDP values were 14.5–21.0 (70% AS), 60.7– 2.2 (80% AS), 261.6 (90% AS), and b) values (in mJ per ) were −501.9 to −1023.8 (70% AS), −1247.6 to −1773.0 (80% AS), −1934.5 (90% AS). Hence, CDP and are expected to assess the true functional severity of PA stenosis.
    Keywords: Pulmonary Artery Stenosis ; Congenital Heart Disease ; In Vitro Experiments ; Functional Diagnostic Parameters ; Subject-Specific ; Medicine ; Engineering ; Anatomy & Physiology
    ISSN: 0021-9290
    E-ISSN: 1873-2380
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