UID:
almahu_9949838474902882
Format:
1 online resource (554 pages)
Edition:
1st ed.
ISBN:
9780443137891
Series Statement:
Micro and Nano Technologies Series
Note:
Intro -- Nanozymes: Approachable Bio-applications -- Copyright -- Contents -- Contributors -- Preface -- Chapter 1: An overview of nanozymes -- 1.1. Introduction -- 1.2. A brief history of nanozyme research and development -- 1.3. Definition of nanozymes -- 1.4. Types of nanozymes -- 1.4.1. Metal-based nanozymes -- 1.4.2. Metal oxide-based nanozymes -- 1.4.3. Carbon-based nanozymes -- 1.4.4. Hybrid nanozymes -- 1.5. Catalytic activities of nanozymes -- 1.6. Synthesis methods -- 1.7. Advantages of using nanozymes over traditional enzymes -- 1.7.1. Enhanced stability -- 1.7.2. Ease of synthesis -- 1.7.3. Large-scale production -- 1.7.4. Tunable properties -- 1.7.5. Versatility -- 1.8. Factors influencing the performance of nanozymes -- 1.8.1. Aggregation -- 1.8.2. Surface modification -- 1.8.3. Size and configuration -- 1.8.4. Environment -- 1.8.5. Chemical stability -- 1.8.6. Storage -- 1.9. Applications of nanozymes in bioapplications -- 1.9.1. Biomedical imaging -- 1.9.2. Biosensing -- 1.9.3. Immunoassays -- 1.9.4. Theragnostic -- 1.9.5. Drug delivery -- 1.9.6. Antibacterial therapy -- 1.9.7. Environmental applications of nanozymes -- 1.9.8. Industrial applications of nanozymes -- 1.9.8.1. Catalysis -- 1.9.8.2. Manufacturing processes -- 1.10. Limitations of nanozymes -- 1.10.1. Limited substrate specificity -- 1.10.2. Reproducibility challenges -- 1.10.3. Limited understanding -- 1.10.4. Regulatory hurdles -- 1.11. Future directions for nanozyme research and development -- 1.11.1. Smart nanozymes -- 1.11.2. Integration with other nanomaterials -- 1.11.3. In vivo applications -- 1.11.4. Environmental applications -- 1.12. Conclusion -- References -- Chapter 2: Classification of nanozymes -- 2.1. Introduction -- 2.2. Oxidoreductase-mimetic nanozymes -- 2.2.1. Oxidase-mimetic nanozymes -- 2.2.1.1. Laccase-mimetic nanozymes.
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2.2.1.2. Sulfite oxidase-mimetc nanozymes -- 2.2.1.3. Glucose oxidase-mimetic nanozymes -- 2.2.2. Catalase nanozymes -- 2.2.3. Peroxidase-mimetic nanozymes -- 2.2.3.1. Glutathione peroxidase-mimetic nanozymes -- 2.2.3.2. Haloperoxidase-mimetic nanozymes -- 2.2.4. Special oxidoreductase-mimetic nanozymes -- 2.2.5. Superoxide dismutase nanozymes -- 2.2.5.1. Cerium-based SOD-mimetic nanozymes -- 2.2.5.2. Carbon-based SOD nanozymes -- 2.2.5.3. Other metals -- 2.3. Hydrolase family -- 2.4. Conclusion -- References -- Chapter 3: A review on nanozymes mechanisms and kinetics -- 3.1. Introduction -- 3.2. Peroxidase-like activity -- 3.2.1. Free radical (Fenton) mechanism -- 3.2.2. Electron-transfer mechanism -- 3.2.3. Mechanisms of carbon systems -- 3.2.4. Mechanism of nanoceria -- 3.3. Superoxide dismutase-like activity -- 3.3.1. Mechanism of metal and metal oxides -- 3.3.2. Mechanism of nanoceria -- 3.3.3. Mechanism of carbon systems -- 3.4. Oxidase-like activity -- 3.4.1. Mechanism of metals -- 3.4.2. Mechanism of nanoceria -- 3.4.3. Mechanism of carbon systems -- 3.5. Catalase-like activity -- 3.5.1. Homolytic mechanism -- 3.5.2. Heterolytic mechanism -- 3.6. Hydrolase-like activity -- 3.7. Dehydrogenase-like activity -- 3.8. Kinetic modeling of nanozyme activity -- 3.9. Conclusions -- References -- Chapter 4: Recent progress in the synthesis of nanozymes and their functionalization -- 4.1. Introduction -- 4.2. Classification of nanozymes -- 4.2.1. Peroxidase mimics -- 4.2.1.1. Iron-based -- 4.2.1.2. Vanadium-based nanozymes -- 4.2.1.3. Manganese-based nanozymes -- 4.2.1.4. Other peroxidase-mimicking enzyme -- 4.2.2. Oxidase-mimic nanozymes -- 4.2.2.1. Gold-based nanozymes -- 4.2.2.2. Platinum-based nanozymes -- 4.2.2.3. Molybdenum-based nanozymes -- 4.2.2.4. Copper-based nanozymes -- 4.2.3. SOD mimics -- 4.2.3.1. Cerium-based nanozymes.
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4.2.3.2. Carbon-based nanozymes -- 4.2.4. Catalase mimics -- 4.2.5. Multifunctional nanozymes -- 4.3. Synthesis of nanozymes -- 4.3.1. Top-down synthesis -- 4.3.2. Bottom-up synthesis -- 4.4. The impact of surface modification on the activity of nanozymes -- 4.4.1. Functionalization gives rise to different nanozyme activity for a single nanoparticle: Case studies of Mn, Fe, and ... -- 4.5. Conclusion and future perspective -- Acknowledgment -- References -- Chapter 5: Construction of functionally specific nanozymes for cancer theragnostic -- 5.1. Introduction -- 5.2. Implementation of nanozymes for the preparation of theragnostics in cancer -- 5.3. Nanozymes in cancer bioimaging -- 5.4. Nanozymes in cancer diagnosis -- 5.5. Conclusion -- Acknowledgment -- References -- Chapter 6: Opportunities and trends in therapeutics application of nanozymes -- 6.1. Introduction -- 6.2. Classification of nanozymes -- 6.2.1. Oxidase-mimic nanozymes -- 6.2.2. Peroxidase-mimic nanozymes -- 6.2.3. Catalase-mimic nanozymes -- 6.2.4. Superoxidase-mimic nanozymes -- 6.3. Therapeutic applications of nanozymes -- 6.3.1. Nanozyme-based cancer therapy -- 6.3.2. Nanozyme-based infectious disease therapy -- 6.3.3. Nanozyme-based cardiovascular disease therapy -- 6.3.4. Nanozyme-based neurodegenerative disorders therapy -- 6.3.5. Nanozyme-based drug delivery -- 6.4. Future prospectives and challenges -- 6.4.1. Conclusion -- Acknowledgments -- References -- Chapter 7: Nanozyme-based antibacterials against bacterial infections -- 7.1. Introduction -- 7.2. Mechanism of antibacterial nanozymes -- 7.2.1. ROS regulation -- 7.2.2. HOBr/Cl generation -- 7.2.3. Extracellular DNA clearance -- 7.3. Design consideration in antibacterial nanozymes -- 7.3.1. Metal-based nanozymes -- 7.3.2. Carbon-based nanozymes -- 7.3.3. Single-atom nanozymes -- 7.3.4. MOFs-based nanozymes.
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7.3.5. Other classes of nanozymes -- 7.4. Biocompatibility of antibacterial nanozymes -- 7.5. Combinatorial applications of antibacterial nanozymes -- 7.5.1. Integration of nanozymes in multifunctional antibacterial biomaterial designs -- 7.5.2. Photodynamic and photothermal inactivation with nanozymes -- 7.6. Conclusion and future directions -- Acknowledgments -- References -- Chapter 8: Nanozymes-based detection of clinically important pathogens -- 8.1. Introduction -- 8.2. Types of nanozymes and the mechanisms of nanozyme catalysis -- 8.3. Nanozyme applications in pathogen detection -- 8.3.1. Detection of bacterial pathogens -- 8.3.2. Viral detection via nanozymes -- 8.3.3. Detection of fungi and parasites -- 8.4. Conclusion -- 8.5. Challenges and future perspectives -- References -- Chapter 9: Nanozyme for diabetes care -- 9.1. Introduction -- 9.1.1. Types of DM -- 9.2. Methods -- 9.2.1. Glucose detection technologies: From traditional to innovative methods -- 9.2.2. The development of biosensors and point-of-care devices for DM with nanoenzymes -- 9.2.3. Alternative diabetes care methods: Insulin delivery using nanozymes -- 9.2.4. Challenging diabetic wounds with nanozymes -- 9.2.4.1. Causes of diabetic wounds -- 9.2.5. Therapeutic approaches with nanozymes -- 9.3. Conclusion -- Acknowledgments -- References -- Chapter 10: Nanozymes-based multifunctional platforms for uric acid detection in patients -- 10.1. Introduction -- 10.2. Nanozymes: Concepts and properties -- 10.3. Uric acid detection using nanozymes -- 10.3.1. Colorimetric sensor -- 10.3.2. Electrochemical sensor -- 10.3.3. Fluorescence sensor -- 10.3.4. Surface-enhanced Raman scattering (SERS) sensors -- 10.4. Challenges and future directions -- 10.5. Conclusion -- Acknowledgments -- References.
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Chapter 11: Recent advances in the use of nanozymes for optical detection of biologically relevant small molecules -- Abbreviations -- 11.1. Introduction -- 11.2. Detection of small biomolecules utilizing the activity of nanozymes -- 11.2.1. Detection of amino acids -- 11.2.1.1. Cysteine and homocysteine -- 11.2.1.2. Arginine and tyrosine -- 11.2.2. Detection of peptides -- 11.2.2.1. Glutathione -- 11.2.2.2. Brain natriuretic peptide and amyloid-β-peptide -- 11.2.3. Detection of neurotransmitters -- 11.2.3.1. Epinephrine -- 11.2.3.2. Dopamine -- 11.2.3.3. Aldosterone -- 11.2.3.4. Acetylcholine -- 11.2.4. Detection of antioxidants -- 11.2.4.1. Detection of ascorbic acid -- 11.2.4.2. Detection of uric acid -- 11.2.5. Detection of glucose -- 11.3. Conclusion and future prospects -- References -- Chapter 12: Nanozyme-based tests for rapid diagnosis of SARS-COV-2 -- 12.1. Introduction -- 12.1.1. History and origin of SARS-CoV-2 -- 12.1.2. Idea of rapid diagnosis -- 12.1.3. Nanozyme-based platforms -- 12.2. Recent application of nanozyme-based rapid kit for the detection of SARS-CoV-2 -- 12.3. Conclusion and future perspective -- References -- Chapter 13: Colorimetric detection of hydrogen peroxide using nanozymes -- 13.1. Introduction -- 13.2. The importance of H2O2 detection for life sciences -- 13.3. Nanozymes for colorimetric hydrogen peroxide detection -- 13.3.1. Inorganic-based nanozymes -- 13.3.2. Carbon-based nanozymes -- 13.3.3. Hybrid/organic nanozymes -- 13.4. Challenges and future perspective -- References -- Chapter 14: Detection of adulteration in foods using functional nanozymes -- 14.1. A global overview of adulteration -- 14.2. Kinds of adulteration and adulterant types -- 14.3. Health issues related to adulteration -- 14.4. Common ways of detecting adulterants: A glimpse into the classical methods.
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14.5. Detection techniques employing nanotechnology vis-à-vis conventional methods.
Additional Edition:
ISBN 9780443137884
Language:
English
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